GABAergic neuronal lineage development determines clinically actionable targets in diffuse hemispheric glioma, H3G34-mutant

Authors: Liu, Ilon, Alencastro Veiga Cruzeiro, Gustavo, Bjerke, Lynn, Rogers, Rebecca F., Grabovska, Yura, Beck, Alexander, Mackay, Alan, Barron, Tara, Hack, Olivia A., Quezada, Michael A., Molinari, Valeria, Shaw, McKenzie L., Perez-Somarriba, Marta, Temelso, Sara, Raynaud, Florence, Ruddle, Ruth, Panditharatna, Eshini, Englinger, Bernhard, Mire, Hafsa M., Jiang, Li, Nascimento, Andrezza, LaBelle, Jenna, Haase, Rebecca, Rozowsky, Jacob, Neyazi, Sina, Baumgartner, Alicia-Christina, Castellani, Sophia, Hoffman, Samantha E., Cameron, Amy, Morrow, Murry, Nguyen, Quang-De, Pericoli, Giulia, Madlener, Sibylle, Mayr, Lisa, Dorfer, Christian, Geyeregger, Rene, Rota, Christopher, Ricken, Gerda, Ligon, Keith L., Alexandrescu, Sanda, Cartaxo, Rodrigo T., Lau, Benison, Uphadhyaya, Santhosh, Koschmann, Carl, Braun, Emelie, Danan-Gotthold, Miri, Hu, Lijuan, Siletti, Kimberly, Sundström, Erik, Hodge, Rebecca, Lein, Ed, Agnihotri, Sameer, Eisenstat, David D., Stapleton, Simon, King, Andrew, Bleil, Cristina, Mastronuzzi, Angela, Cole, Kristina A., Waanders, Angela J., Montero Carcaboso, Angel, Schüller, Ulrich, Hargrave, Darren, Vinci, Maria, Carceller, Fernando, Haberler, Christine, Slavc, Irene, Linnarsson, Sten, Gojo, Johannes, Monje, Michelle, Jones, Chris, Filbin, Mariella G.

Source: In Cancer Cell 9 September 2024 42(9):1528-1548

Automated software vulnerability detection with machine learning

Authors: Harer, Jacob A., Kim, Louis Y., Russell, Rebecca L., Ozdemir, Onur, Kosta, Leonard R., Rangamani, Akshay, Hamilton, Lei H., Centeno, Gabriel I., Key, Jonathan R., Ellingwood, Paul M., Antelman, Erik, Mackay, Alan, McConley, Marc W., Opper, Jeffrey M., Chin, Peter, Lazovich, Tomo

Subject Terms: Computer Science - Software Engineering, Computer Science - Machine Learning, Statistics - Machine Learning

Access URL: http://arxiv.org/abs/1803.04497

MRI and Molecular Characterization of Pediatric High-Grade Midline Thalamic Gliomas: The HERBY Phase II Trial

Authors: Rodriguez, Daniel, Calmon, Raphael, Aliaga, Esther Sanchez, Warren, Daniel, Warmuth-Metz, Monika, Jones, Chris, Mackay, Alan, Varlet, Pascale, Le Deley, Marie-Cécile, Hargrave, Darren

Source: Radiology. 304(1):174-182

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCRN629557695&indx=1&recIds=ETOCRN629557695

An exceptionally rare case of a diffuse midline glioma with concomitant H3.1 K27M and G34R mutations in the HIST1H3C (H3C3) gene.

Authors: Reisz, Zita, Pereira, Rita, Nevis, Smitha, Mackay, Alan, Bhaw, Leena, Grabovska, Yura, Laxton, Ross, Molinari, Valeria, Burford, Anna, Clark, Barnaby, Bleil, Cristina, Zebian, Bassel, Pace, Erika, Weiser, Annette, Carceller, Fernando, Marshall, Lynley, King, Andrew, Bodi, Istvan, Al-Sarraj, Safa, Jones, Chris

Source: Acta Neuropathologica Communications; 1/16/2025, Vol. 13 Issue 1, p1-6, 6p

Subject Terms: MEDICAL sciences, BRAIN tumors, WHOLE genome sequencing, MAGNETIC resonance imaging, DNA methylation

Beyond crystals: the dialectic of materials and information

Authors: Cartwright, Julyan H. E., Mackay, Alan L.

Source: Phil. Trans. R. Soc. A 370, 2807-2822, 2012

Subject Terms: Nonlinear Sciences - Adaptation and Self-Organizing Systems, Condensed Matter - Materials Science, Quantitative Biology - Genomics

Access URL: http://arxiv.org/abs/1207.3997

Germline-driven replication repair-deficient high-grade gliomas exhibit unique hypomethylation patterns

Authors: Dodgshun, Andrew J., Fukuoka, Kohei, Edwards, Melissa, Bianchi, Vanessa J., Das, Anirban, Sexton-Oates, Alexandra, Larouche, Valérie, Vanan, Magimairajan I., Lindhorst, Scott, Yalon, Michal, Mason, Gary, Crooks, Bruce, Constantini, Shlomi, Massimino, Maura, Chiaravalli, Stefano, Ramdas, Jagadeesh, Mason, Warren, Ashraf, Shamvil, Farah, Roula, Van Damme, An, Opocher, Enrico, Hamid, Syed Ahmer, Ziegler, David S., Samuel, David, Cole, Kristina A., Tomboc, Patrick, Stearns, Duncan, Thomas, Gregory A., Lossos, Alexander, Sullivan, Michael, Hansford, Jordan R., Mackay, Alan, Jones, Chris, Jones, David T. W., Ramaswamy, Vijay, Hawkins, Cynthia, Bouffet, Eric, Tabori, Uri

Source: Acta neuropathologica. 140(5):765-776

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100168071837.0x000001&indx=1&recIds=ETOCvdc_100168071837.0x000001

Histone H3 wild-type DIPG/DMG overexpressing EZHIP extend the spectrum diffuse midline gliomas with PRC2 inhibition beyond H3-K27M mutation

Authors: Castel, David, Kergrohen, Thomas, Tauziède-Espariat, Arnault, Mackay, Alan, Ghermaoui, Samia, Lechapt, Emmanuèle, Pfister, Stefan M., Kramm, Christof M., Boddaert, Nathalie, Blauwblomme, Thomas, Puget, Stéphanie, Beccaria, Kévin, Jones, Chris, Jones, David T. W., Varlet, Pascale, Grill, Jacques, Debily, Marie-Anne

Source: Acta neuropathologica. 139(6):1109-1113

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100168072274.0x000001&indx=1&recIds=ETOCvdc_100168072274.0x000001

Gliomatosis cerebri in children: A poor prognostic phenotype of diffuse gliomas with a distinct molecular profile.

Authors: Nussbaumer, Gunther, Benesch, Martin, Grabovska, Yura, Mackay, Alan, Castel, David, Grill, Jacques, Alonso, Marta M, Antonelli, Manila, Bailey, Simon, Baugh, Joshua N, Biassoni, Veronica, Blattner-Johnson, Mirjam, Broniscer, Alberto, Carai, Andrea, Colafati, Giovanna Stefania, Colditz, Niclas, Corbacioglu, Selim, Crampsie, Shauna, Entz-Werle, Natacha, Eyrich, Matthias

Source: Neuro-Oncology; Sep2024, Vol. 26 Issue 9, p1723-1737, 15p

The oncolytic virus Delta-24-RGD elicits an antitumor effect in pediatric glioma and DIPG mouse models

Authors: Martínez-Vélez, Naiara, Garcia-Moure, Marc, Marigil, Miguel, González-Huarriz, Marisol, Puigdelloses, Montse, Gallego Pérez-Larraya, Jaime, Zalacaín, Marta, Marrodán, Lucía, Varela-Guruceaga, Maider, Laspidea, Virginia, Aristu, Jose, Ramos, Luis, Tejada-Solís, Sonia, Díez-Valle, Ricardo, Jones, Chris, Mackay, Alan, Martínez-Climent, Jose, García-Barchino, Maria, Raabe, Eric, Monje, Michelle, Becher, Oren, Junier, Marie, El-Habr, Elias, Chneiweiss, Herve, Aldave, Guillermo, Jiang, Hong, Fueyo, Juan, Patiño-García, Ana, Gomez-Manzano, Candelaria, Alonso, Marta

Source: Nature communications. 10(1):1-10

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100153445220.0x000001&indx=1&recIds=ETOCvdc_100153445220.0x000001

Comprehensive Sampling of Gene Expression in Human Cell Lines with Massively Parallel Signature Sequencing

Authors: Jongeneel, C. Victor, Iseli, Christian, Stevenson, Brian J., Riggins, Gregory J., Lal, Anita, Mackay, Alan, Harris, Robert A., O'Hare, Michael J., Neville, A. Munro, Strausberg, Robert L.

Source: Proceedings of the National Academy of Sciences of the United States of America, 2003 Apr . 100(8), 4702-4705.

Access URL: https://www.jstor.org/stable/3144005

Integrated Molecular Meta-Analysis of 1,000 Pediatric High-Grade and Diffuse Intrinsic Pontine Glioma

Authors: Mackay, Alan, Burford, Anna, Carvalho, Diana, Izquierdo, Elisa, Fazal-Salom, Janat, Taylor, Kathryn R., Bjerke, Lynn, Clarke, Matthew, Vinci, Mara, Nandhabalan, Meera, Temelso, Sara, Popov, Sergey, Molinari, Valeria, Raman, Pichai, Waanders, Angela J., Han, Harry J., Gupta, Saumya, Marshall, Lynley, Zacharoulis, Stergios, Vaidya, Sucheta, Mandeville, Henry C., Bridges, Leslie R., Martin, Andrew J., Al-Sarraj, Safa, Chandler, Christopher, Ng, Ho-Keung, Li, Xingang, Mu, Kun, Trabelsi, Saoussen, Brahim, Dorra H’mida-Ben, Kisljakov, Alexei N., Konovalov, Dmitry M., Moore, Andrew S., Carcaboso, Angel Montero, Sunol, Mariona, de Torres, Carmen, Cruz, Ofelia, Mora, Jaume, Shats, Ludmila I., Stavale, João N., Bidinotto, Lucas T., Reis, Rui M., Entz-Werle, Natacha, Farrell, Michael, Cryan, Jane, Crimmins, Darach, Caird, John, Pears, Jane, Monje, Michelle, Debily, Marie-Anne, Castel, David, Grill, Jacques, Hawkins, Cynthia, Nikbakht, Hamid, Jabado, Nada, Baker, Suzanne J., Pfister, Stefan M., Jones, David T.W., Fouladi, Maryam, von Bueren, André O., Baudis, Michael, Resnick, Adam, Jones, Chris

Source: In Cancer Cell 9 October 2017 32(4):520-537

Neural Precursor-Derived Pleiotrophin Mediates Subventricular Zone Invasion by Glioma

Authors: Qin, Elizabeth Y., Cooper, Dominique D., Abbott, Keene L., Lennon, James, Nagaraja, Surya, Mackay, Alan, Jones, Chris, Vogel, Hannes, Jackson, Peter K., Monje, Michelle

Source: In Cell 24 August 2017 170(5):845-859

A PML/Slit Axis Controls Physiological Cell Migration and Cancer Invasion in the CNS

Authors: Amodeo, Valeria, A, Deli, Betts, Joanne, Bartesaghi, Stefano, Zhang, Ying, Richard-Londt, Angela, Ellis, Matthew, Roshani, Rozita, Vouri, Mikaella, Galavotti, Sara, Oberndorfer, Sarah, Leite, Ana Paula, Mackay, Alan, Lampada, Aikaterini, Stratford, Eva Wessel, Li, Ningning, Dinsdale, David, Grimwade, David, Jones, Chris, Nicotera, Pierluigi, Michod, David, Brandner, Sebastian, Salomoni, Paolo

Source: In Cell Reports 11 July 2017 20(2):411-426

The ten-year evolutionary trajectory of a highly recurrent paediatric high grade neuroepithelial tumour with MN1:BEND2 fusion

Authors: Burford, Anna, Mackay, Alan, Popov, Sergey, Vinci, Maria, Carvalho, Diana, Clarke, Matthew, Izquierdo, Elisa, Avery, Aimee, Jacques, Thomas, Ingram, Wendy, Moore, Andrew, Frawley, Kieran, Hassall, Timothy, Robertson, Thomas, Jones, Chris

Source: Scientific reports. 8(1):1-10

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100111621200.0x000001&indx=1&recIds=ETOCvdc_100111621200.0x000001

Functional diversity and cooperativity between subclonal populations of pediatric glioblastoma and diffuse intrinsic pontine glioma cells

Authors: Vinci, Mara, Burford, Anna, Molinari, Valeria, Kessler, Ketty, Popov, Sergey, Clarke, Matthew, Taylor, Kathryn, Pemberton, Helen, Lord, Christopher, Gutteridge, Alice, Forshew, Tim, Carvalho, Diana, Marshall, Lynley, Qin, Elizabeth, Ingram, Wendy, Moore, Andrew, Ng, Ho-Keung, Trabelsi, Saoussen, H'mida-Ben Brahim, Dorra, Entz-Werle, Natacha, Zacharoulis, Stergios, Vaidya, Sucheta, Mandeville, Henry, Bridges, Leslie, Martin, Andrew, Al-Sarraj, Safa, Chandler, Christopher, Sunol, Mariona, Mora, Jaume, de Torres, Carmen, Cruz, Ofelia, Carcaboso, Angel, Monje, Michelle, Mackay, Alan, Jones, Chris

Source: Nature medicine. 24(8):1204-1215

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100174860019.0x000001&indx=1&recIds=ETOCvdc_100174860019.0x000001

Curved Surfaces in Chemical Structure

Authors: Klinowski, Jacek, Mackay, Alan L., Terrones, Humberto

Source: Philosophical Transactions: Mathematical, Physical and Engineering Sciences, 1996 Sep . 354(1715), 1975-1987.

Access URL: https://www.jstor.org/stable/54574

New Brain Tumor Entities Emerge from Molecular Classification of CNS-PNETs

Authors: Sturm, Dominik, Orr, Brent A., Toprak, Umut H., Hovestadt, Volker, Jones, David T.W., Capper, David, Sill, Martin, Buchhalter, Ivo, Northcott, Paul A., Leis, Irina, Ryzhova, Marina, Koelsche, Christian, Pfaff, Elke, Allen, Sariah J., Balasubramanian, Gnanaprakash, Worst, Barbara C., Pajtler, Kristian W., Brabetz, Sebastian, Johann, Pascal D., Sahm, Felix, Reimand, Jüri, Mackay, Alan, Carvalho, Diana M., Remke, Marc, Phillips, Joanna J., Perry, Arie, Cowdrey, Cynthia, Drissi, Rachid, Fouladi, Maryam, Giangaspero, Felice, Łastowska, Maria, Grajkowska, Wiesława, Scheurlen, Wolfram, Pietsch, Torsten, Hagel, Christian, Gojo, Johannes, Lötsch, Daniela, Berger, Walter, Slavc, Irene, Haberler, Christine, Jouvet, Anne, Holm, Stefan, Hofer, Silvia, Prinz, Marco, Keohane, Catherine, Fried, Iris, Mawrin, Christian, Scheie, David, Mobley, Bret C., Schniederjan, Matthew J., Santi, Mariarita, Buccoliero, Anna M., Dahiya, Sonika, Kramm, Christof M., von Bueren, André O., von Hoff, Katja, Rutkowski, Stefan, Herold-Mende, Christel, Frühwald, Michael C., Milde, Till, Hasselblatt, Martin, Wesseling, Pieter, Rößler, Jochen, Schüller, Ulrich, Ebinger, Martin, Schittenhelm, Jens, Frank, Stephan, Grobholz, Rainer, Vajtai, Istvan, Hans, Volkmar, Schneppenheim, Reinhard, Zitterbart, Karel, Collins, V. Peter, Aronica, Eleonora, Varlet, Pascale, Puget, Stephanie, Dufour, Christelle, Grill, Jacques, Figarella-Branger, Dominique, Wolter, Marietta, Schuhmann, Martin U., Shalaby, Tarek, Grotzer, Michael, van Meter, Timothy, Monoranu, Camelia-Maria, Felsberg, Jörg, Reifenberger, Guido, Snuderl, Matija, Forrester, Lynn Ann, Koster, Jan, Versteeg, Rogier, Volckmann, Richard, van Sluis, Peter, Wolf, Stephan, Mikkelsen, Tom, Gajjar, Amar, Aldape, Kenneth, Moore, Andrew S., Taylor, Michael D., Jones, Chris, Jabado, Nada, Karajannis, Matthias A., Eils, Roland, Schlesner, Matthias, Lichter, Peter, von Deimling, Andreas, Pfister, Stefan M., Ellison, David W., Korshunov, Andrey, Kool, Marcel

Source: In Cell 25 February 2016 164(5):1060-1072

Inhibition of exosome biogenesis affects cell motility in heterogeneous sub-populations of paediatric-type diffuse high-grade gliomas.

Authors: Pericoli, Giulia, Galardi, Angela, Paolini, Alessandro, Petrilli, Lucia Lisa, Pepe, Gerardo, Palma, Alessandro, Colletti, Marta, Ferretti, Roberta, Giorda, Ezio, Levi Mortera, Stefano, Burford, Anna, Carai, Andrea, Mastronuzzi, Angela, Mackay, Alan, Putignani, Lorenza, Jones, Chris, Pascucci, Luisa, Peinado, Hector, Helmer-Citterich, Manuela, de Billy, Emmanuel

Source: Cell & Bioscience; 11/13/2023, Vol. 13 Issue 1, p1-24, 24p

Subject Terms: CELL motility, EXOSOMES, CELLULAR control mechanisms, GLIOMAS, MOLECULAR cloning

Pediatric pan-central nervous system tumor analysis of immune-cell infiltration identifies correlates of antitumor immunity

Authors: Grabovska, Yura, Mackay, Alan, O'Hare, Patricia, Crosier, Stephen, Finetti, Martina, Schwalbe, Edward C., Pickles, Jessica C., Fairchild, Amy R., Avery, Aimee, Cockle, Julia, Hill, Rebecca, Lindsey, Janet, Hicks, Debbie, Kristiansen, Mark, Chalker, Jane, Anderson, John, Hargrave, Darren, Jacques, Thomas S., Straathof, Karin, Bailey, Simon, Jones, Chris, Clifford, Steven C., Williamson, Daniel

Source: Nature communications. 11(1)

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100174525851.0x000001&indx=1&recIds=ETOCvdc_100174525851.0x000001

Correlation of in vitro lymphocyte radiosensitivity and gene expression with late normal tissue reactions following curative radiotherapy for breast cancer

Authors: Finnon, Paul, Kabacik, Sylwia, MacKay, Alan, Raffy, Claudine, A’Hern, Roger, Owen, Roger, Badie, Christophe, Yarnold, John, Bouffler, Simon

Source: In Radiotherapy and Oncology December 2012 105(3):329-336