Aspergillus-mediated allergic airway inflammation is triggered by dendritic cell recognition of a defined spore morphotype

Authors: Houlder, Emma L. ^{a, b}, Gago, Sara ^c, Vere, George ^d, Furlong-Silva, Julio ^d, Conn, Daniel ^d, Hickey, Emer ^d, Khan, Saba ^a, Thomson, Darren ^{c, d}, Shepherd, Mark W. ^a, Lebedinec, Ressa ^c, Brown, Gordon D. ^d, Horsnell, William ^d, Bromley, Mike ^c, MacDonald, Andrew S. ^a, Cook, Peter C. ^{a, d, ∗}

Source: In The Journal of Allergy and Clinical Immunology March 2025 155(3):988-1001

Engineering the glioblastoma microenvironment using TLR7/8 agonist-complexed graphene oxide nanosheets

Authors: Stylianou, Maria ^{1, 2}, Kisby, Thomas ^{1, 2, ∗}, Despotopoulou, Despoina ³, Parker, Helen ⁴, Thawley, Alexandra ¹, Arashvand, Kiana ¹, Lozano, Neus ³, MacDonald, Andrew S. ⁴, Kostarelos, Kostas ^{1, 2, 3, 5, 6, ∗∗}

Source: In Cell Reports Physical Science 15 January 2025 6(1)

T helper 2 cells control monocyte to tissue-resident macrophage differentiation during nematode infection of the pleural cavity

Authors: Finlay, Conor M., Parkinson, James E., Zhang, Lili, Chan, Brian H.K., Ajendra, Jesuthas, Chenery, Alistair, Morrison, Anya, Kaymak, Irem, Houlder, Emma L., Murtuza Baker, Syed, Dickie, Ben R., Boon, Louis, Konkel, Joanne E., Hepworth, Matthew R., MacDonald, Andrew S., Randolph, Gwendalyn J., Rückerl, Dominik, Allen, Judith E.

Source: In Immunity 9 May 2023 56(5):1064-1081

Graphene oxide modulates dendritic cell ability to promote T cell activation and cytokine productionElectronic supplementary information (ESI) available. See DOI: https://doi.org/10.1039/d2nr02169b

Authors: Parker, Helen, Gravagnuolo, Alfredo Maria, Vranic, Sandra, Crica, Livia Elena, Newman, Leon, Carnell, Oliver, Bussy, Cyrill, Dookie, Rebecca S., Prestat, Eric, Haigh, Sarah J., Lozano, Neus, Kostarelos, Kostas, MacDonald, Andrew S.

Source: Nanoscale. 14(46):17297-17314

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100166691329.0x000001&indx=1&recIds=ETOCvdc_100166691329.0x000001

A population of naive‐like CD4+ T cells stably polarized to the TH1 lineage

Authors: Lo, Jonathan W., de Mucha, Maria Vila, Henderson, Stephen, Roberts, Luke B., Constable, Laura E., Garrido‐Mesa, Natividad, Hertweck, Arnulf, Stolarczyk, Emilie, Houlder, Emma L., Jackson, Ian, MacDonald, Andrew S., Powell, Nick, Neves, Joana F., Howard, Jane K., Jenner, Richard G., Lord, Graham M.

Source: European journal of immunology. 52(4):566-581

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100164074745.0x000001&indx=1&recIds=ETOCvdc_100164074745.0x000001

CD11c identifies microbiota and EGR2‐dependent MHCII+ serous cavity macrophages with sexually dimorphic fate in mice

Authors: Bain, Calum C., Louwe, Pieter A., Steers, Nicholas J., Bravo‐Blas, Alberto, Hegarty, Lizi M., Pridans, Clare, Milling, Simon W.F., MacDonald, Andrew S., Rückerl, Dominik, Jenkins, Stephen J.

Source: European journal of immunology. 52(8):1243-1257

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100157777304.0x000001&indx=1&recIds=ETOCvdc_100157777304.0x000001

The impact of the lung environment on macrophage development, activation and function: diversity in the face of adversity

Authors: Bain, Calum C., MacDonald, Andrew S.

Source: In Mucosal Immunology February 2022 15(2):223-234

The role of the host gut microbiome in the pathophysiology of schistosomiasis

Authors: Stark, Klara A., Rinaldi, Gabriel, Cortés, Alba, Costain, Alice, MacDonald, Andrew S., Cantacessi, Cinzia

Source: Parasite immunology. 45(4)

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100182190882.0x000001&indx=1&recIds=ETOCvdc_100182190882.0x000001

Subclinical Inflammation of the Ocular Surface in Soft Contact Lens Wear

Authors: Saliman, Noor Haziq, Morgan, Philip B., MacDonald, Andrew S., Maldonado-Codina, Carole

Source: Cornea. 39(2):146-154

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100190002963.0x000001&indx=1&recIds=ETOCvdc_100190002963.0x000001

Intestinal mucin activates human dendritic cells and IL-8 production in a glycan-specific manner

Authors: Melo-Gonzalez, Felipe, Fenton, Thomas M., Forss, Cecilia, Smedley, Catherine, Goenka, Anu, MacDonald, Andrew S., Thornton, David J., Travis, Mark A.

Source: In Journal of Biological Chemistry 1 June 2018 293(22):8543-8553

Type I interferons provide additive signals for murine regulatory B cell induction by Schistosoma mansoni eggs

Authors: Obieglo, Katja, Costain, Alice, Webb, Lauren M., Ozir‐Fazalalikhan, Arifa, Brown, Shelia L., MacDonald, Andrew S., Smits, Hermelijn H.

Source: European journal of immunology. 49(8):1226-1234

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100087228665.0x000001&indx=1&recIds=ETOCvdc_100087228665.0x000001

Enteric helminth-induced type I interferon signaling protects against pulmonary virus infection through interaction with the microbiota

Authors: McFarlane, Amanda J., McSorley, Henry J., Davidson, Donald J., Fitch, Paul M., Errington, Claire, Mackenzie, Karen J., Gollwitzer, Eva S., Johnston, Chris J.C., MacDonald, Andrew S., Edwards, Michael R., Harris, Nicola L., Marsland, Benjamin J., Maizels, Rick M., Schwarze, Jürgen

Source: In The Journal of Allergy and Clinical Immunology October 2017 140(4):1068-1078

Tumor progression locus 2 reduces severe allergic airway inflammation by inhibiting Ccl24 production in dendritic cells

Authors: Kannan, Yashaswini, Li, Yanda, Coomes, Stephanie M., Okoye, Isobel S., Pelly, Victoria S., Sriskantharajah, Srividya, Gückel, Eva, Webb, Lauren, Czieso, Stephanie, Nikolov, Nikolay, MacDonald, Andrew S., Ley, Steven C., Wilson, Mark S.

Source: In The Journal of Allergy and Clinical Immunology February 2017 139(2):655-666

Human NK Cells Lyse Th2-Polarizing Dendritic Cells via NKp30 and DNAM-1

Authors: Walwyn-Brown, Katherine, Guldevall, Karolin, Saeed, Mezida, Pende, Daniela, Önfelt, Björn, MacDonald, Andrew S., Davis, Daniel M.

Source: Journal of immunology. 201(7):2028-2041

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCRN617418627&indx=1&recIds=ETOCRN617418627

Effects of Mycobacterium vaccae NCTC 11659 and Lipopolysaccharide Challenge on Polarization of Murine BV-2 Microglial Cells.

Authors: Desmond, Luke W., Holbrook, Evan M., Wright, Caelan T. O., Zambrano, Cristian A., Stamper, Christopher E., Bohr, Adam D., Frank, Matthew G., Podell, Brendan K., Moreno, Julie A., MacDonald, Andrew S., Reber, Stefan O., Hernández-Pando, Rogelio, Lowry, Christopher A.

Source: International Journal of Molecular Sciences; Jan2024, Vol. 25 Issue 1, p474, 20p

Subject Terms: LIPOPOLYSACCHARIDES, REVERSE transcriptase polymerase chain reaction, MICROGLIA, GENE expression, COMPLEMENT receptors, MYCOBACTERIUM

The adult murine heart has a sparse, phagocytically active macrophage population that expands through monocyte recruitment and adopts an ‘M2’ phenotype in response to Th2 immunologic challenge

Authors: Mylonas, Katie J., Jenkins, Stephen J., Castellan, Raphael F.P., Ruckerl, Dominik, McGregor, Kieran, Phythian-Adams, Alexander T., Hewitson, James P., Campbell, Sharon M., MacDonald, Andrew S., Allen, Judith E., Gray, Gillian A.

Source: In Immunobiology July 2015 220(7):924-933

Chemokines form complex signals during inflammation and disease that can be decoded by extracellular matrix proteoglycans.

Authors: Ridley, Amanda J. L., Ou, Yaqing, Karlsson, Richard, Pun, Nabina, Birchenough, Holly L., Mulholland, Iashia Z., Birch, Mary L., MacDonald, Andrew S., Jowitt, Thomas A., Lawless, Craig, Miller, Rebecca L., Dyer, Douglas P.

Source: Science Signaling; 11/7/2023, Vol. 16 Issue 810, p1-14, 14p

Subject Terms: CHEMOKINE receptors, CELL receptors, CHEMOKINES, EXTRACELLULAR matrix, PROTEOGLYCANS, GENE expression

Alternative activation of macrophages by filarial nematodes is MyD88-independent

Authors: Mylonas, Katie J., Hoeve, Marieke A., MacDonald, Andrew S., Allen, Judith E.

Source: In Immunobiology April 2013 218(4):570-578

Combinatorial Tim‐3 and PD‐1 activity sustains antigen‐specific Th1 cell numbers during blood‐stage malaria

Authors: Dookie, Rebecca S., Villegas‐Mendez, Ana, Kroeze, Hans, Barrett, Jordan R., Draper, Simon J., Franke‐Fayard, Blandine M., Janse, Chris J., MacDonald, Andrew S., Couper, Kevin N.

Source: Parasite immunology. 42(9)

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100108144683.0x000001&indx=1&recIds=ETOCvdc_100108144683.0x000001

Dermal IRF4+ dendritic cells and monocytes license CD4+ T helper cells to distinct cytokine profiles

Authors: Hilligan, Kerry L., Tang, Shiau-Choot, Hyde, Evelyn J., Roussel, Elsa, Mayer, Johannes U., Yang, Jianping, Wakelin, Kirsty A., Schmidt, Alfonso J., Connor, Lisa M., Sher, Alan, MacDonald, Andrew S., Ronchese, Franca

Source: Nature communications. 11(1)

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100183403552.0x000001&indx=1&recIds=ETOCvdc_100183403552.0x000001