Decreasing interleukin-6 levels after TIPS predict outcomes in decompensated cirrhosis

Authors: Kornfehl, Andrea ^{1, 2}, Tiede, Anja ^{3, 4}, Hemetsberger, Paul ^{1, 2}, Kappel, Julia ^{1, 2, 5}, Müllner-Bucsics, Theresa ^{1, 2, 5}, Stockhoff, Lena ⁶, Rieland, Hannah ³, Reider, Lukas ⁷, Dominik, Nina ^{1, 2}, Kramer, Georg ^{1, 2}, Trauner, Michael ^{1, 5}, Mandorfer, Mattias ^{1, 2, 5}, Falk, Christine ⁸, Maasoumy, Benjamin ^{3, 4}, Reiberger, Thomas ^{1, 2, 5, 9, ⁎}, Hartl, Lukas ^{1, 2, 5}

Source: In JHEP Reports April 2025 7(4)

QuickStroop for screening for minimal hepatic encephalopathy in patients with cirrhosis

Authors: Labenz, Christian ^{1, 2, ⁎}, Gairing, Simon J. ^{1, 2}, Kaps, Leonard ^{1, 2}, Ehrenbauer, Alena F. ³, Schleicher, Eva M. ^{1, 2}, Mengel, Sophie ^{1, 2}, Egge, Julius F.M. ³, Gabriel, Maria M. ⁴, Galle, Peter R. ^{1, 2}, Wedemeyer, Heiner ³, Zipprich, Alexander ^{5, 6}, Ripoll, Cristina ^{5, 6}, Greinert, Robin ^{5, †}, Maasoumy, Benjamin ^{3, †}

Source: In JHEP Reports March 2025 7(3)

Severe alpha-1 antitrypsin deficiency is associated with a higher risk of complications after first decompensation than other aetiologies of cirrhosis

Authors: Balcar, Lorenz ^{1, 2, †}, Fromme, Malin ^{3, †}, Kappe, Naomi ⁴, Schäfer, Benedikt ⁵, Fraňková, Soňa ⁶, van Melkebeke, Lukas ⁷, Stolk, Jan ⁴, Jachs, Mathias ^{1, 2, 8}, Semmler, Georg ^{1, 2}, Hofer, Benedikt S. ^{1, 2}, Tergast, Tammo L. ⁸, Rieland, Hannah ⁸, Karl, Anna Sophie ³, Sperl, Jan ⁶, Wagner, Martin ⁹, Pons, Mònica ¹⁰, Hofer, Harald ¹¹, Peck-Radosavljevic, Markus ¹², Trauner, Michael ¹, Reiberger, Thomas ^{1, 2}, Maasoumy, Benjamin ⁸, Zoller, Heinz ⁵, van Hoek, Bart ⁴, Verbeek, Jef ⁷, Strnad, Pavel ^{3, 13, ‡}, Mandorfer, Mattias ^{1, 2, ⁎, ‡}

Source: In JHEP Reports March 2025

Early Occurrence of Hepatic Encephalopathy Following Transjugular Intrahepatic Portosystemic Shunt Insertion is Linked to Impaired Survival: A Multicenter Cohort Study

Authors: Reincke, Marlene ¹, Rieland, Hannah ², Rohrer, Charlotte ¹, Thimme, Robert ¹, Tiede, Anja ^{2, 3}, Stockhoff, Lena ⁴, Meyer, Bernhard C. ⁵, Kimmann, Markus ⁶, Gödiker, Juliana ⁶, Uschner, Frank Erhard ⁶, Kabelitz, Martin A. ^{1, ∗}, Sandmann, Lisa ^{1, 2, ∗}, Praktiknjo, Michael ³, Mauz, Jim B. ¹, Auer, Timo Alexander ⁴, Bruns, Tony ⁵, Chang, Johannes ⁶, Engelmann, Cornelius ⁷, Fehrenbach, Uli ⁴, Hinrichs, Jan ⁸, Jansen, Christian ⁶, Kloeckner, Roman ⁹, Kluwe, Johannes ¹⁰, Köhler, Michael ¹¹, Meyer, Carsten ¹², Piecha, Felix ¹⁰, Pollmanns, Maike Rebecca ⁵, Ripoll, Cristina ¹³, Schultheiss, Michael ^{14, 15}, Seifert, Leon Louis ^{16, 17}, Stöhr, Fabian ¹⁸, Sturm, Lukas ^{14, 15}, Trebicka, Jonel ³, Zipprich, Alexander ¹³, Labenz, Christian ¹⁹, Bettinger, Dominik ¹⁴, Maasoumy, Benjamin ^{1, 2, ∗}

Source: In Clinical Gastroenterology and Hepatology

Minimal residual ascites 3 months after TIPS implantation predicts worse clinical outcomes in patients with cirrhosis

Authors: Mauz, Jim Benjamin ^{1, †}, Hartl, Lukas ^{2, 3, †}, Kornfehl, Andrea ², Schütte, Sarah Lisa ¹, Hemetsberger, Paul ², Müllner-Bucsics, Theresa ^{2, 3}, Jachs, Mathias ^{2, 3}, Tiede, Anja ^{1, 4}, Rieland, Hannah ¹, Schwarz, Michael ^{2, 3}, Dominik, Nina ^{2, 3}, Kramer, Georg ^{2, 3}, Meyer, Bernhard ⁵, Reider, Lukas ⁶, Trauner, Michael ², Wedemeyer, Heiner ^{1, 4}, Mandorfer, Mattias ^{2, 3}, Maasoumy, Benjamin ^{1, 4}, Reiberger, Thomas ^{2, 3, 7, ⁎, ‡}, Tergast, Tammo Lambert ^{1, 2, 3, ‡}

Source: In JHEP Reports January 2025

Freiburg index of post-TIPS survival (FIPS) identifies patients at risk of further decompensation and ACLF after TIPS

Authors: Sturm, Lukas ^{1, 2}, Schultheiss, Michael ^{1, 2}, Stöhr, Fabian ³, Labenz, Christian ⁴, Maasoumy, Benjamin ⁵, Tiede, Anja ⁵, Praktiknjo, Michael ⁶, Seifert, Leon Louis ^{6, 7}, Auer, Timo Alexander ⁸, Fehrenbach, Uli ⁸, Piecha, Felix ⁹, Harberts, Aenne ⁹, Kluwe, Johannes ⁹, Bruns, Tony ¹⁰, Pollmanns, Maike Rebecca ¹⁰, Chang, Johannes ¹¹, Grobelski, Jakub ¹¹, Jansen, Christian ¹¹, Meyer, Carsten ¹², Reincke, Marlene ¹, Rohrer, Charlotte ¹, Philipp Arbabi, Sina Rastin ¹, Kimmann, Markus ⁶, Ripoll, Cristina ¹³, Zipprich, Alexander ¹³, Hinrichs, Jan ¹⁴, Koehler, Michael ¹⁵, Trebicka, Jonel ⁶, Kloeckner, Roman ¹⁶, Engelmann, Cornelius ¹⁷, Thimme, Robert ¹, Bettinger, Dominik ^{1, ⁎}

Source: In Journal of Hepatology January 2025

Spleen stiffness measurement by vibration-controlled transient elastography at 100 Hz for non-invasive predicted diagnosis of clinically significant portal hypertension in patients with compensated advanced chronic liver disease: a modelling study

Authors: Kuner, Charlotte, Stättermayer, Albert Friedrich, Trauner, Michael, Hernández-Gea, Virginia, Payancé, Audrey, Roux, Olivier, Issoufaly, Tazime, Valainathan, Shantha, de Broucker, Chloé, Torres, María, Stefanescu, Horia, Platon, Monica, Fodor, Andreea, Nicoara-Farcau, Oana, Bianchini, Marcello, Guasconi, Tomas, Vanwolleghem, Thomas, Schoenmakers, Lotte, Vonghia, Luisa, Labenz, Christian, Dajti, Elton, Colecchia, Luigi, Vanderschueren, Emma, Sandmann, Lisa, Greenfield, Helena, Jachs, Mathias, Odriozola, Aitor, Turon, Fanny, Moga, Lucile, Téllez, Luis, Fischer, Petra, Saltini, Dario, Kwanten, Wilhelmus J, Grasso, Maria, Llop, Elba, Mendoza, Yuly P, Armandi, Angelo, Thalhammer, Julia, Pardo, Carlos, Colecchia, Antonio, Ravaioli, Federico, Maasoumy, Benjamin, Laleman, Wim, Presa, José, Schattenberg, Jörn M, Berzigotti, Annalisa, Calleja, José L, Calvaruso, Vincenza, Francque, Sven, Schepis, Filippo, Procopet, Bogdan, Albillos, Agustín, Rautou, Pierre-Emmanuel, García-Pagán, Juan C, Puente, Ángela, Fortea, José I, Reiberger, Thomas, Mandorfer, Mattias ^*

Source: In The Lancet Gastroenterology & Hepatology December 2024 9(12):1111-1120

High Prevalence and Clinical Relevance of Intrapulmonary Vascular Dilatations in Patients Undergoing TIPS Implantation

Authors: Mauz, Jim B., Rieland, Hannah, Berliner, Dominik, Tiede, Anja, Stockhoff, Lena, Hinrichs, Jan B., Wedemeyer, Heiner, Meyer, Bernhard C., Olsson, Karen M., Maasoumy, Benjamin, Tergast, Tammo L.

Source: In Clinical Gastroenterology and Hepatology September 2024 22(9):1867-1877

Folic acid supplementation is associated with a decreased mortality and reduced hospital readmission in patients with decompensated alcohol-related liver cirrhosis

Authors: Buttler, Laura, Tiede, Anja, Griemsmann, Marie, Rieland, Hannah, Mauz, Jim, Kahlhöfer, Julia, Wedemeyer, Heiner, Cornberg, Markus, Tergast, Tammo L., Maasoumy, Benjamin, Hupa-Breier, Katharina L.

Source: In Clinical Nutrition August 2024 43(8):1719-1727

Validation of Baveno VII criteria and other non-invasive diagnostic algorithms for clinically significant portal hypertension in hepatitis delta

Authors: Jachs, Mathias, Sandmann, Lisa, Hartl, Lukas, Tergast, Tammo, Schwarz, Michael, Bauer, David Josef Maria, Balcar, Lorenz, Ehrenbauer, Alena, Hofer, Benedikt Silvester, Cornberg, Markus, Lenzen, Henrike, Deterding, Katja, Trauner, Michael, Mandorfer, Mattias, Wedemeyer, Heiner, Reiberger, Thomas, Maasoumy, Benjamin

Source: In Journal of Hepatology August 2024 81(2):248-257

Post-treatment LSM rather than change during treatment predicts decompensation in patients with cACLD after HCV cure

Authors: Maria Agostini, Sofia, Balcar, Lorenz, Battistella, Sara, Chromy, David, Cornberg, Markus, Deterding, Katja, Fernandez, Inmaculada, Fernandez-Rodriguez, Conrado, Gea, Francisco, Koeck, Fiona, Krawanja, Julia, Neumayer, Daniela, Riado, Daniel, Rincón, Diego, Schwabl, Philipp, Simbrunner, Benedikt, Trauner, Michael, Uson, Clara, Wedemeyer, Heiner, Semmler, Georg, Alonso López, Sonia, Pons, Monica, Lens, Sabela, Dajti, Elton, Griemsmann, Marie, Zanetto, Alberto, Burghart, Lukas, Hametner-Schreil, Stefanie, Hartl, Lukas, Manzano, Marisa, Rodriguez-Tajes, Sergio, Zanaga, Paola, Schwarz, Michael, Gutierrez, María Luisa, Jachs, Mathias, Pocurull, Anna, Polo, Benjamín, Ecker, Dominik, Mateos, Beatriz, Izquierdo, Sonia, Real, Yolanda, Ahumada, Adriana, Bauer, David Josef Maria, Mauz, Jim Benjamin, Casanova-Cabral, Michelle, Gschwantler, Michael, Russo, Francesco Paolo, Azzaroli, Francesco, Maasoumy, Benjamin, Reiberger, Thomas, Forns, Xavier, Genesca, Joan, Bañares, Rafael, Mandorfer, Mattias

Source: In Journal of Hepatology July 2024 81(1):76-83

CXCR6+CD69+ CD8+ T cells in ascites are associated with disease severity in patients with cirrhosis

Authors: Niehaus, Christian ^{1, 2, 3, 4, 5}, Klein, Sebastian ^{1, 2, 3, 6}, Strunz, Benedikt ⁷, Freyer, Erich ^{1, 2, 3, 4}, Maasoumy, Benjamin ^{1, 4}, Wedemeyer, Heiner ^{1, 4, 5}, Björkström, Niklas K. ⁷, Kraft, Anke R.M. ^{1, 2, 3, 4, 5}, Cornberg, Markus ^{1, 2, 3, 4, 5, 8, ⁎}

Source: In JHEP Reports June 2024 6(6)

HBV DNA and HBsAg Levels at 24 Weeks Off-Treatment Predict Clinical Relapse and HBsAg Loss in HBeAg-Negative Patients Who Discontinued Antiviral Therapy

Authors: Sonneveld, Milan J., Chiu, Shao-Ming, Park, Jun Yong, Brakenhoff, Sylvia M., Kaewdech, Apichat, Seto, Wai-Kay, Tanaka, Yasuhito, Carey, Ivana, Papatheodoridi, Margarita, Colombatto, Piero, van Bömmel, Florian, Janssen, Harry L., Berg, Thomas, Zoulim, Fabien, Ahn, Sang Hoon, Dalekos, George N., Erler, Nicole S., Brunetto, Maurizia, Wedemeyer, Heiner, Cornberg, Markus, Yuen, Man-Fung, Agarwal, Kosh, Boonstra, Andre, Buti, Maria, Piratvisuth, Teerha, Papatheodoridis, George, Chen, Chien-Hung, Maasoumy, Benjamin

Source: In Gastroenterology January 2024 166(1):168-177

Predicting overt hepatic encephalopathy after TIPS: Value of three minimal hepatic encephalopathy tests

Authors: Ehrenbauer, Alena F., Schneider, Hannah, Stockhoff, Lena, Tiede, Anja, Lorenz, Charlotte, Dirks, Meike, Witt, Jennifer, Gabriel, Maria M., Wedemeyer, Heiner, Hinrichs, Jan B., Weissenborn, Karin, Maasoumy, Benjamin

Source: In JHEP Reports September 2023 5(9)

Lower pretreatment HBV DNA levels are associated with better off-treatment outcomes after nucleo(s)tide analogue withdrawal in patients with HBeAg-negative chronic hepatitis B: A multicentre cohort study

Authors: Sonneveld, Milan J., Chiu, Shao-Ming, Park, Jun Yong, Brakenhoff, Sylvia M., Kaewdech, Apichat, Seto, Wai-Kay, Tanaka, Yasuhito, Carey, Ivana, Papatheodoridi, Margarita, Colombatto, Piero, van Bömmel, Florian, Berg, Thomas, Zoulim, Fabien, Ahn, Sang Hoon, Dalekos, George N., Erler, Nicole S., Brunetto, Maurizia, Wedemeyer, Heiner, Cornberg, Markus, Yuen, Man-Fung, Agarwal, Kosh, Boonstra, Andre, Buti, Maria, Piratvisuth, Teerha, Papatheodoridis, George, Chen, Chien-Hung, Maasoumy, Benjamin

Source: In JHEP Reports August 2023 5(8)

Reverse inflammaging: Long-term effects of HCV cure on biological age

Authors: Oltmanns, Carlos, Liu, Zhaoli, Mischke, Jasmin, Tauwaldt, Jan, Mekonnen, Yonatan Ayalew, Urbanek-Quaing, Melanie, Debarry, Jennifer, Maasoumy, Benjamin, Wedemeyer, Heiner, Kraft, Anke R.M., Xu, Cheng-Jian, Cornberg, Markus

Source: In Journal of Hepatology January 2023 78(1):90-98

Limited Value of HBV‐RNA for Relapse Prediction After Nucleos(t)ide Analogue Withdrawal in HBeAg‐negative Hepatitis B Patients.

Authors: Ohlendorf, Valerie, Wübbolding, Maximilian, Höner zu Siederdissen, Christoph, Bremer, Birgit, Deterding, Katja, Wedemeyer, Heiner, Cornberg, Markus, Maasoumy, Benjamin

Source: Journal of Viral Hepatitis; Apr2025, Vol. 32 Issue 4, p1-10, 10p

Subject Terms: HEPATITIS B, HEPATITIS B virus, DISEASE relapse, VACCINE trials, NUCLEOSIDE derivatives, ANTIVIRAL agents

TIPS insertion and systemic inflammation: Is it ever too late to lower portal pressure? Correspondence to editorial on “Insertion of a transjugular intrahepatic portosystemic shunt leads to sustained reversal of systemic inflammation in patients with decompensated liver cirrhosis”.

Authors: Tiede, Anja, Maasoumy, Benjamin

Source: Clinical & Molecular Hepatology; Apr2025, Vol. 31 Issue 2, pe176-e179, 4p

Probability of HBsAg loss after nucleo(s)tide analogue withdrawal depends on HBV genotype and viral antigen levels

Authors: Sonneveld, Milan J., Chiu, Shao-Ming, Park, Jun Yong, Brakenhoff, Sylvia M., Kaewdech, Apichat, Seto, Wai-Kay, Tanaka, Yasuhito, Carey, Ivana, Papatheodoridi, Margarita, van Bömmel, Florian, Berg, Thomas, Zoulim, Fabien, Ahn, Sang Hoon, Dalekos, George N., Erler, Nicole S., Höner zu Siederdissen, Christoph, Wedemeyer, Heiner, Cornberg, Markus, Yuen, Man-Fung, Agarwal, Kosh, Boonstra, Andre, Buti, Maria, Piratvisuth, Teerha, Papatheodoridis, George, Chen, Chien-Hung, Maasoumy, Benjamin

Source: In Journal of Hepatology May 2022 76(5):1042-1050

Hepatitis E virus is highly resistant to alcohol-based disinfectants

Authors: Behrendt, Patrick, Friesland, Martina, Wißmann, Jan-Erik, Kinast, Volker, Stahl, Yannick, Praditya, Dimas, Hueffner, Lucas, Nörenberg, Pia Maria, Bremer, Birgit, Maasoumy, Benjamin, Steinmann, Jochen, Becker, Britta, Paulmann, Dajana, Brill, Florian H.H., Steinmann, Joerg, Ulrich, Rainer G., Brüggemann, Yannick, Wedemeyer, Heiner, Todt, Daniel, Steinmann, Eike

Source: In Journal of Hepatology May 2022 76(5):1062-1069