Factor XII contact activation can be prevented by targeting 2 unique patches in its epidermal growth factor-like 1 domain with a nanobody

Authors: Frunt, Rowan, El Otmani, Hinde, Smits, Simone, Clark, Chantal C., Maas, Coen

Source: In Journal of Thrombosis and Haemostasis September 2024 22(9):2562-2575

Insights in the Prothrombotic Changes After Implantation of a Left Ventricular Assist Device in Patients With End-Stage Heart Failure: A Longitudinal Observational Study

Authors: Liesdek, Omayra C.D., Urbanus, Rolf T., de Maat, Steven, de Heer, Linda M., Ramjankhan, Faiz Z., Sebastian, Silvie A.E., Huisman, Albert, de Jonge, Nicolaas, Vink, Aryan, Fischer, Kathelijn, Maas, Coen, Suyker, Willem J.L., Schutgens, Roger E.G.

Source: ASAIO journal. 69(5):438-444

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100189984585.0x000001&indx=1&recIds=ETOCvdc_100189984585.0x000001

Restriction of C1-inhibitor activity in hereditary angioedema by dominant-negative effects of disease-associated SERPING1 gene variants

Authors: Ryø, Laura Barrett, Haslund, Didde, Rovsing, Anne Bruun, Pihl, Rasmus, Sanrattana, Wariya, de Maat, Steven, Palarasah, Yaseelan, Maas, Coen, Thiel, Steffen, Mikkelsen, Jacob Giehm

Source: In The Journal of Allergy and Clinical Immunology November 2023 152(5):1218-1236

In vivo generation of thrombin in patients with liver disease without apparent evidence of activation of the intrinsic or extrinsic pathway of coagulation

Authors: Elvers, Fynn L., Stamouli, Marilena, Adelmeijer, Jelle, Jeyanesan, Dhaarica, Bernal, William, Maas, Coen, Patel, Vishal C., Lisman, Ton

Source: In Journal of Thrombosis and Haemostasis August 2023 21(8):2078-2088

A reactive center loop–based prediction platform to enhance the design of therapeutic SERPINs

Authors: Sanrattana, Wariya, Sefiane, Thibaud, Smits, Simone, van Kleef, Nadine D., Fens, Marcel H., Lenting, Peter J., Maas, Coen, de Maat, Steven

Source: Proceedings of the National Academy of Sciences of the United States of America, 2021 Nov 01. 118(45), 1-10.

Access URL: https://www.jstor.org/stable/27093653

VWF-targeted thrombolysis to overcome rh-tPA resistance in experimental murine ischemic stroke models

Authors: van Moorsel, Marc V. A., de Maat, Steven, Vercruysse, Kristof, van Leeuwen, Esther M., Jacqmarcq, Charlène, Bonnard, Thomas, Vivien, Denis, van der Worp, H. Bart, Dijkhuizen, Rick M., Maas, Coen

Source: Blood. 140(26):2844-2848

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100183236132.0x000001&indx=1&recIds=ETOCvdc_100183236132.0x000001

Microlyse: a thrombolytic agent that targets VWF for clearance of microvascular thrombosis

Authors: de Maat, Steven, Clark, Chantal C., Barendrecht, Arjan D., Smits, Simone, van Kleef, Nadine D., El Otmani, Hinde, Waning, Manon, van Moorsel, Marc, Szardenings, Michael, Delaroque, Nicolas, Vercruysse, Kristof, Urbanus, Rolf T., Sebastian, Silvie, Lenting, Peter J., Hagemeyer, Christoph, Renné, Thomas, Vanhoorelbeke, Karen, Tersteeg, Claudia, Maas, Coen

Source: Blood. 139(4):597-607

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100183242145.0x000001&indx=1&recIds=ETOCvdc_100183242145.0x000001

Recombinant human C1 esterase inhibitor as prophylactic treatment in idiopathic non‐histaminergic angioedema

Authors: Alizadeh Aghdam, Mehran, Hofman, Zonne L. M., Meertens, Michelle, Lebens, Ans, Hack, C. Erik, Knulst, André C., Maas, Coen, Röckmann, Heike

Source: Allergy. 77(12):3673-3676

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100175475412.0x000001&indx=1&recIds=ETOCvdc_100175475412.0x000001

VhH anti‐thrombomodulin clone 1 inhibits TAFI activation and enhances fibrinolysis in human whole blood under flow

Authors: van Moorsel, Marc V. A., Poolen, Geke C., Koekman, Cornelis A., Verhoef, Sandra, de Maat, Steven, Barendrecht, Arjan, van Kleef, Nadine D., Meijers, Joost C. M., Schiffelers, Raymond M., Maas, Coen, Urbanus, Rolf T.

Source: Journal of thrombosis and haemostasis. 20(5):1213-1222

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100154986411.0x000001&indx=1&recIds=ETOCvdc_100154986411.0x000001

Thrombosis pathways in COVID‐19 vs. influenza‐associated ARDS: A targeted proteomics approach

Authors: Rademaker, Emma, Doorduijn, Dennis J., Kusadasi, Nuray, Maas, Coen, Drylewicz, Julia, Huisman, Albert, Hoefer, Imo E., Bonten, Marc J. M., Derde, Lennie P. G., Rooijakkers, Suzan H. M., Cremer, Olaf L.

Source: Journal of thrombosis and haemostasis. 20(5):1206-1212

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100154986406.0x000001&indx=1&recIds=ETOCvdc_100154986406.0x000001

Altered fibrin network structure and fibrinolysis in intensive care unit patients with COVID‐19, not entirely explaining the increased risk of thrombosis

Authors: Vries, Judith J., Visser, Chantal, Geers, Lotte, Slotman, Johan A., van Kleef, Nadine D., Maas, Coen, Bax, Hannelore I., Miedema, Jelle R., Gorp, Eric C. M., Goeijenbier, Marco, Akker, Johannes P. C., Endeman, Henrik, Rijken, Dingeman C., Kruip, Marieke J. H. A., Maat, Moniek P. M.

Source: Journal of thrombosis and haemostasis. 20(6):1412-1420

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100150465887.0x000001&indx=1&recIds=ETOCvdc_100150465887.0x000001

Targeted SERPIN (TaSER): A dual‐action antithrombotic agent that targets platelets for SERPIN delivery

Authors: Sanrattana, Wariya, Smits, Simone, Barendrecht, Arjan D., Kleef, Nadine D., El Otmani, Hinde, Zivkovic, Minka, Roest, Mark, Renné, Thomas, Clark, Chantal C., Maat, Steven, Maas, Coen

Source: Journal of thrombosis and haemostasis. 20(2):353-365

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100148406424.0x000001&indx=1&recIds=ETOCvdc_100148406424.0x000001

Lupus anticoagulant associates with thrombosis in patients with COVID‐19 admitted to intensive care units: A retrospective cohort study

Authors: Noordermeer, Tessa, Schutgens, Roger E.G., Visser, Chantal, Rademaker, Emma, de Maat, Moniek P.M., Jansen, A.J. Gerard, Limper, Maarten, Cremer, Olaf L., Kruip, Marieke J.H.A., Endeman, Henrik, Maas, Coen, de Laat, Bas, Urbanus, Rolf T. ^*, van de Beek, D., Brouwer, M.C., de Bruin, S., Coppens, M., van Es, N., van Haaps, T.F., Juffermans, N.P., Muller, M.C.A., Vlaar, A.P.J., Hertogh, C.M.P.M., Heunks, L.M.A., Hugtenburg, J.G., van Kooten, J., Nossent, E.J., Smulders, Y., Tuinman, P.R., Vonk Noordegraaf, A., Grootenboers, M.J.J.H., van Guldener, C., Kant, M., Lansbergen, A., Faber, J., Hajer, G., Stemerdink, A., van den Akker, J., Bierings, R., Endeman, H., Goeijenbier, M., Hunfeld, N.G.M., van Gorp, E.C.M., Gommers, D.A.M.P.J., Koopmans, M.P.G., Kruip, M.J.H.A., Kuiken, T., Langerak, T., Leebeek, Lauw, M.N., de Maat, M.P.M., Noack, D., Paats, M.S., Raadsen, M.P., Rockx, B., Rokx, C., Schurink, C.A.M., Tong‐Minh, K., van den Toorn, L., den Uil, C.A., Visser, C., Boutkourt, F., Roest, T., Douma, R.A., de Haan, L.R., ten Wolde, M., Bemelmans, R.H.H., Festen, B., Stads, S., de Jager, C.P.C., Simons, K.S., Antoni, M.L., Bos, M.H., Burggraaf, J.L.I., Cannegieter, S.C., Eikenboom, H.C.J., den Exter, P.L., Geelhoed, J.J.M., Huisman, M.V., de Jonge, E., Kaptein, F.H.J., Klok, F.A., Kroft, L.J.M., Lijfering, W.M., Nab, L., Ninaber, M.K., Putter, H., Ramai, S.R.S., da Rocha Rondon, A.M., Roukens, A.H.E., Stals, M.A.M., Versteeg, H.H., Vliegen, H.W., van Vlijmen, B.J.M., van de Berg, T., Bruggemann, R., van Bussel, B.C.T., ten Cate, H., ten Cate‐Hoek, A., Hackeng, T.M., Henskens, ir.Y., Hulshof, A., Mulder, M., Olie, R.H., Schurgers, L., Spaetgens, B., Spronk, H., Winckers, K., Nieuwenhuizen, L., Franken, B., Schrover, I.M., de Waal, E.G.M., Beishuizen, A., Cornet, A., Krabbe, J., Kramers, K., Leentjens, J., de Mast, Q., Middeldorp, S., Brouwer, R.E., Ellerbroek, J.L.J., Tijmensen, J., Hovens, M.M C., Oostdijk, E.A.N., Westerhof, B.D., Faber, L.M., van den Biggelaar, M., Meijers, J.C.M., Voorberg, J., Kevenaar, M.E., Soei, Y.L., Wils, E.J., Croles, F.N., de Laat, B., Kamphuisen, P.W., Vink, R., Lisman, T., Meijer, K., van Tichelaar, Y.I.G., Cremer, O.L., Geersing, G., Kaasjager, H.A.H., Kusadasi, N., Huisman, A., Maas, C., Nijkeuter, M., Schutgens, R.E.G., Creveldkliniek, Van, Urbanus, R.T., Westerink, J., Faber, H.J., Koster, S.C.E., van Montfort, P., van Twist, D.J.L.

Source: In Research and Practice in Thrombosis and Haemostasis August 2022 6(6)

Altered fibrin network structure and fibrinolysis in intensive care unit patients with COVID‐19, not entirely explaining the increased risk of thrombosis

Authors: de Vries, Judith J., Visser, Chantal, Geers, Lotte, Slotman, Johan A., van Kleef, Nadine D., Maas, Coen, Bax, Hannelore I., Miedema, Jelle R., van Gorp, Eric C.M., Goeijenbier, Marco, van den Akker, Johannes P.C., Endeman, Henrik, Rijken, Dingeman C., Kruip, Marieke J.H.A., de Maat, Moniek P.M. ^*

Source: In Journal of Thrombosis and Haemostasis June 2022 20(6):1412-1420

Illustrated State‐of‐the‐Art Capsules of the ISTH 2021 Congress

Authors: Krishnaswamy, Sriram, Ageno, Walter, Arabi, Yaseen, Barbui, Tiziano, Cannegieter, Suzanne, Carrier, Marc, Cleuren, Audrey C., Collins, Peter, Panicot‐Dubois, Laurence, Freedman, Jane E., Freson, Kathleen, Hogg, Philip, James, Andra H., Kretz, Colin A., Lavin, Michelle, Leebeek, Frank W.G., Li, Weikai, Maas, Coen, Machlus, Kellie, Makris, Michael, Martinelli, Ida, Medved, Leonid, Neerman‐Arbez, Marguerite, O’Donnell, James S., O'Sullivan, Jamie, Rajpurkar, Madhvi, Schroeder, Verena, Spiegel, Paul Clinton, Jr, Stanworth, Simon J., Green, Laura, Undas, Anetta

Source: In Research and Practice in Thrombosis and Haemostasis July 2021 5(5)

Defective NET clearance contributes to sustained FXII activation in COVID-19-associated pulmonary thrombo-inflammation

Authors: Englert, Hanna, Rangaswamy, Chandini, Deppermann, Carsten, Sperhake, Jan-Peter, Krisp, Christoph, Schreier, Danny, Gordon, Emma, Konrath, Sandra, Haddad, Munif, Pula, Giordano, Mailer, Reiner K., Schlüter, Hartmut, Kluge, Stefan, Langer, Florian, Püschel, Klaus, Panousis, Kosta, Stavrou, Evi X., Maas, Coen, Renné, Thomas, Frye, Maike

Source: In EBioMedicine May 2021 67

Xenotropic and polytropic retrovirus receptor 1 regulates procoagulant platelet polyphosphate

Authors: Mailer, Reiner K. ^*, Allende, Mikel ^*, Heestermans, Marco, Schweizer, Michaela, Deppermann, Carsten, Frye, Maike, Pula, Giordano, Odeberg, Jacob, Gelderblom, Mathias, Rose-John, Stefan, Sickmann, Albert, Blankenberg, Stefan, Huber, Tobias B., Kubisch, Christian, Maas, Coen, Gambaryan, Stepan, Firsov, Dmitri, Stavrou, Evi X., Butler, Lynn M., Renné, Thomas ^*

Source: In Blood 11 March 2021 137(10):1392-1405

Caging the dragon: Research approach to COVID‐19–related thrombosis

Authors: Kruip, Marieke J.H.A. ^*, Cannegieter, Suzanne C., ten Cate, Hugo, van Gorp, Eric C.M., Juffermans, Nicole P., Klok, Frederikus A., Maas, Coen, Vonk‐Noordegraaf, Anton

Source: In Research and Practice in Thrombosis and Haemostasis February 2021 5(2):278-291

Serum proteases prevent bacterial biofilm formation: role of kallikrein and plasmin

Authors: Arenas, Jesús, Szabo, Zalan, van der Wal, Jelle, Maas, Coen, Riaz, Tahira, Tønjum, Tone, Tommassen, Jan

Source: Virulence. 12(1):2902-2917

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100139152675.0x000001&indx=1&recIds=ETOCvdc_100139152675.0x000001

Influenza-induced thrombocytopenia is dependent on the subtype and sialoglycan receptor and increases with virus pathogenicity

Authors: Jansen, A. J. Gerard ^*, Spaan, Thom ^*, Low, Hui Zhi ^*, Di Iorio, Daniele, van den Brand, Judith, Tieke, Malte, Barendrecht, Arjan, Rohn, Kerstin, van Amerongen, Geert, Stittelaar, Koert, Baumgärtner, Wolfgang, Osterhaus, Albert, Kuiken, Thijs, Boons, Geert-Jan, Huskens, Jurriaan, Boes, Marianne, Maas, Coen, van der Vries, Erhard ^*

Source: In Blood Advances 14 July 2020 4(13):2967-2978