The clinical and genetic spectrum of twenty-six individuals with hearing loss affected by MYO15A variants

Authors: Saeid Morovvati, Mina Mohammadi Sarband, Samaneh Doostmohammadi, Sima Rayat, Hessamaldin Emamdjomeh, Mohammad Farhadi, Alimohamad Asghari, Masoud Garshasbi, Masoumeh Falah

Source: Scientific Reports, Vol 15, Iss 1, Pp 1-13 (2025)

Subject Terms: Hearing loss, DFNB3, MYO15A, Domain, Whole-exome sequencing, Hair cell, Medicine, Science

File Description: electronic resource

Relation: https://doaj.org/toc/2045-2322

Access URL: https://doaj.org/article/6cc7a60b419345a5a4efb5c3b8f52c2b

A Novel Mutation Located in the N‐Terminal Domain of MYO15A Caused Sensorineural Hearing Loss

Authors: Yanli Wang, Zengping Liu, Yong Li, Zhipeng Nie, Baicheng Xu, Yiming Zhu, Shihong Duan, Xingjian Chen, Huan Tan, Jiong Dang, Minxin Guan, Yufen Guo

Source: Molecular Genetics & Genomic Medicine, Vol 12, Iss 12, Pp n/a-n/a (2024)

Subject Terms: deafness, hair cell‐like cell, induced pluripotent stem cells (iPSCs), MYO15A, novel mutation, Genetics, QH426-470

File Description: electronic resource

Relation: https://doaj.org/toc/2324-9269

Access URL: https://doaj.org/article/f7b1e2f3ba36400385d7558d5d2c813c

Mutation Detection in MYO15A Gene in an Iranian Family with Non-Syndromic Hearing Loss

Authors: Mostafa Neissi, Misagh Mohammadi-Asl, Mojdeh Roghani, Adnan Issa Al-Badran, Javad Mohammadi-Asl

Source: International Journal of Biomedicine, Vol 14, Iss 1, Pp 165-169 (2024)

Subject Terms: hearing loss, myo15a gene, mutation, Medicine

File Description: electronic resource

Relation: http://www.ijbm.org/articles/i53/ijbm_14(1)_cr3.pdf; https://doaj.org/toc/2158-0510; https://doaj.org/toc/2158-0529

Access URL: https://doaj.org/article/e2c6e8b7605f436db0544979fb52c505

Novel compound heterozygous MYO15A splicing variants in autosomal recessive non-syndromic hearing loss

Authors: Kaifeng Zheng, Sheng Lin, Jian Gao, Shiguo Chen, Jindi Su, Zhiqiang Liu, Shan Duan

Source: BMC Medical Genomics, Vol 17, Iss 1, Pp 1-10 (2024)

Subject Terms: Non-syndromic hearing loss, MYO15A, Genotype, Splicing variant, Internal medicine, RC31-1245, Genetics, QH426-470

File Description: electronic resource

Relation: https://doaj.org/toc/1755-8794

Access URL: https://doaj.org/article/bf632ff08bc44a9b8111e25f1762ab84

A Novel Deleterious MYO15A Gene Mutation Causes Nonsyndromic Hearing Loss

Authors: Mostafa Neissi, Adnan Al-Badran, Javad Mohammadi-Asl

Source: Iranian Journal of Otorhinolaryngology, Vol 36, Iss 1, Pp 355-360 (2024)

Subject Terms: hearing loss, myo15a gene, mutation, Otorhinolaryngology, RF1-547

File Description: electronic resource

Relation: https://ijorl.mums.ac.ir/article_23663_2d6c7ed83c92a7b22f17ce9d1c653b53.pdf; https://doaj.org/toc/2251-7251; https://doaj.org/toc/2251-726X

Access URL: https://doaj.org/article/c368c458bfb044928e0f7fb52c5549de

Loss-of-function mutations in MYO15A and OTOF cause non-syndromic hearing loss in two Yemeni families

Authors: Maria Asaad, Mona Mahfood, Abdullah Al Mutery, Abdelaziz Tlili

Source: Human Genomics, Vol 17, Iss 1, Pp 1-10 (2023)

Subject Terms: Non-syndromic hearing loss, Frameshift mutation, Splice site mutation, MYO15A gene, OTOF gene, Clinical exome sequencing, Medicine, Genetics, QH426-470

File Description: electronic resource

Relation: https://doaj.org/toc/1479-7364

Access URL: https://doaj.org/article/9844d87463d34aa580257b0829e3ac7c

Spectrum of genetic variants in bilateral sensorineural hearing loss

Authors: Amanat Ali, Mohammed Tabouni, Praseetha Kizhakkedath, Ibrahim Baydoun, Mushal Allam, Anne John, Faiza Busafared, Ayesha Alnuaimi, Fatma Al-Jasmi, Hiba Alblooshi

Source: Frontiers in Genetics, Vol 15 (2024)

Subject Terms: bilateral sensorineural hearing loss, genetic variants, MYO15A gene, SLC26A4 gene, GJB2 gene, CDH23 gene, Genetics, QH426-470

File Description: electronic resource

Relation: https://www.frontiersin.org/articles/10.3389/fgene.2024.1314535/full; https://doaj.org/toc/1664-8021

Access URL: https://doaj.org/article/7e63ed68d0604a8eb3fd8833945c8d3f

Addition of an affected family member to a previously ascertained autosomal recessive nonsyndromic hearing loss pedigree and systematic phenotype-genotype analysis of splice-site variants in MYO15A

Authors: Jin-Yuan Yang, Wei-Qian Wang, Ming-Yu Han, Sha-Sha Huang, Guo-Jian Wang, Yu Su, Jin-Cao Xu, Ying Fu, Dong-Yang Kang, Kun Yang, Xin Zhang, Xing Liu, Xue Gao, Yong-Yi Yuan, Pu Dai

Source: BMC Medical Genomics, Vol 15, Iss 1, Pp 1-16 (2022)

Subject Terms: Autosomal recessive sensorineural hearing loss, Pathogenicity, Splice-site variant, MYO15A, Internal medicine, RC31-1245, Genetics, QH426-470

File Description: electronic resource

Relation: https://doaj.org/toc/1755-8794

Access URL: https://doaj.org/article/ee9185e4b81c4596b2cae7e39d7fd8bc

Whole-Exome Sequencing Reveals Pediatric Rare Syndromic Hearing Loss

Authors: QU Chunyan, ZHOU Yi, CHEN Min, HAO Jinsheng, NI Xin, LIU Haihong

Source: 罕见病研究, Vol 1, Iss 3, Pp 278-282 (2022)

Subject Terms: whole-exome sequencing, syndromic hearing loss, hars2, ush2a, gata3, mitf, myo15a, Medicine

File Description: electronic resource

Relation: https://doaj.org/toc/2097-0501

Access URL: https://doaj.org/article/c8b4eac247484391a513f3e7da71a3c0

Analysis of the genotype–phenotype correlation of MYO15A variants in Chinese non-syndromic hearing loss patients

Authors: Ying Fu, Shasha Huang, Xue Gao, Mingyu Han, Guojian Wang, Dongyang Kang, Yongyi Yuan, Pu Dai

Source: BMC Medical Genomics, Vol 15, Iss 1, Pp 1-32 (2022)

Subject Terms: MYO15A, DFNB3, Hearing loss (HL), Non-syndromic sensorineural hearing loss (NSHL), Internal medicine, RC31-1245, Genetics, QH426-470

File Description: electronic resource

Relation: https://doaj.org/toc/1755-8794

Access URL: https://doaj.org/article/1b643365b4b6485ca558e8e9a523319a

Hereditary etiology of non-syndromic sensorineural hearing loss in the Republic of North Ossetia–Alania

Authors: Nika Petrova, Inna Tebieva, Vitaly Kadyshev, Zalina Getoeva, Natalia Balinova, Andrey Marakhonov, Tatyana Vasilyeva, Evgeny Ginter, Sergey Kutsev, Rena Zinchenko

Source: PeerJ, Vol 11, p e14514 (2023)

Subject Terms: North Ossetia–Alania, GJB2, POU3F4, MYH14, MYO15A, Non-syndromic sensorineural hearing loss, Medicine, Biology (General), QH301-705.5

File Description: electronic resource

Relation: https://peerj.com/articles/14514.pdf; https://peerj.com/articles/14514/; https://doaj.org/toc/2167-8359

Access URL: https://doaj.org/article/ab45bd4b32a24214b6d57e47e6f6377c

Novel MYO15A variants are associated with hearing loss in the two Iranian pedigrees

Authors: Somayeh Khatami, Masomeh Askari, Fatemeh Bahreini, Morteza Hashemzadeh-Chaleshtori, Saeed Hematian, Samira Asgharzade

Source: BMC Medical Genetics, Vol 21, Iss 1, Pp 1-7 (2020)

Subject Terms: MYO15A, Whole exome sequencing, First approach, Consanguineous, Internal medicine, RC31-1245, Genetics, QH426-470

File Description: electronic resource

Relation: http://link.springer.com/article/10.1186/s12881-020-01168-x; https://doaj.org/toc/1471-2350

Access URL: https://doaj.org/article/2c82a74a1b6e4c9198ce2666679245ff

The worldwide frequency of MYO15A gene mutations in patients with autosomal recessive non-syndromic hearing loss: A meta‐analysis

Authors: Mahsa Farjami, Reza Asadi, Fahimeh Afzal Javan, Malihe Alimardani, Saeed Eslami, Sima Mansoori Derakhshan, Atieh Eslahi, Majid Mojarad

Source: Iranian Journal of Basic Medical Sciences, Vol 23, Iss 7, Pp 841-848 (2020)

Subject Terms: autosomal recessive, deafness, meta-analysis, mutation, myo15a, non-syndromic hearing loss, prevalence, Medicine

File Description: electronic resource

Relation: http://ijbms.mums.ac.ir/article_15655_57e2e4a2ae3f2d97d5498723ad6da6b4.pdf; https://doaj.org/toc/2008-3866; https://doaj.org/toc/2008-3874

Access URL: https://doaj.org/article/665f9fff3cc149f6b00d08af0fc5219e

Post-lingual non-syndromic hearing loss phenotype: a polygenic case with 2 biallelic mutations in MYO15A and MITF

Authors: Athar Khalil, Samer Bou Karroum, Rana Barake, Gabriel Dunya, Samer Abou-Rizk, Amina Kamar, Georges Nemer, Marc Bassim

Source: BMC Medical Genetics, Vol 21, Iss 1, Pp 1-8 (2020)

Subject Terms: Congenital hearing loss, Non-syndromic hearing loss, MITF, MYO15A, Whole exome sequencing, Internal medicine, RC31-1245, Genetics, QH426-470

File Description: electronic resource

Relation: https://doaj.org/toc/1471-2350

Access URL: https://doaj.org/article/1de622afa6e14f83b23538966079fefc

Identification of Novel and Recurrent Variants in MYO15A in Ashkenazi Jewish Patients With Autosomal Recessive Nonsyndromic Hearing Loss

Authors: Kevin T. Booth, Yoel Hirsch, Anna C. Vardaro, Josef Ekstein, Devorah Yefet, Adina Quint, Tzvi Weiden, David P. Corey

Source: Frontiers in Genetics, Vol 12 (2021)

Subject Terms: RNA-splicing, deafness, Ashkenazi Jewish, hearing loss, genotype-phenotype correlation, MYO15A, Genetics, QH426-470

File Description: electronic resource

Relation: https://www.frontiersin.org/articles/10.3389/fgene.2021.737782/full; https://doaj.org/toc/1664-8021

Access URL: https://doaj.org/article/0f486bd10405424c832da435731212a3

Genotype-phenotype correlation analysis of MYO15A variants in autosomal recessive non-syndromic hearing loss

Authors: Jing Zhang, Jing Guan, Hongyang Wang, Linwei Yin, Dayong Wang, Lidong Zhao, Huifang Zhou, Qiuju Wang

Source: BMC Medical Genetics, Vol 20, Iss 1, Pp 1-16 (2019)

Subject Terms: MYO15A, DFNB3, Phenotype, Deafness, Internal medicine, RC31-1245, Genetics, QH426-470

File Description: electronic resource

Relation: http://link.springer.com/article/10.1186/s12881-019-0790-2; https://doaj.org/toc/1471-2350

Access URL: https://doaj.org/article/819f600291874c07a3b87931309c92ef

A novel nonsense mutation in MYO15A is associated with non-syndromic hearing loss: a case report

Authors: Di Ma, Shanshan Shen, Hui Gao, Hui Guo, Yumei Lin, Yuhua Hu, Ruanzhang Zhang, Shayan Wang

Source: BMC Medical Genetics, Vol 19, Iss 1, Pp 1-5 (2018)

Subject Terms: Hearing loss, DFNB3, MYO15A, Nonsense mutation, Internal medicine, RC31-1245, Genetics, QH426-470

File Description: electronic resource

Relation: http://link.springer.com/article/10.1186/s12881-018-0657-y; https://doaj.org/toc/1471-2350

Access URL: https://doaj.org/article/cbd1b2240e134ce59e89d4d78616a920

Expansion of phenotypic spectrum of MYO15A pathogenic variants to include postlingual onset of progressive partial deafness

Authors: Mun Young Chang, Chung Lee, Jin Hee Han, Min Young Kim, Hye-Rim Park, Nayoung Kim, Woong-Yang Park, Doo Yi Oh, Byung Yoon Choi

Source: BMC Medical Genetics, Vol 19, Iss 1, Pp 1-10 (2018)

Subject Terms: MYO15A, Phenotype, Deafness, Pathogenic variant, Internal medicine, RC31-1245, Genetics, QH426-470

File Description: electronic resource

Relation: http://link.springer.com/article/10.1186/s12881-018-0541-9; https://doaj.org/toc/1471-2350

Access URL: https://doaj.org/article/19c94b9373f746fda3e005ac3fc4ff5b

Identification of novel variants in MYO15A, OTOF, and RDX with hearing loss by next‐generation sequencing

Authors: Xuejing Bai, Shiyan Nian, Lei Feng, Qingrong Ruan, Xuan Luo, Mengna Wu, Zefeng Yan

Source: Molecular Genetics & Genomic Medicine, Vol 7, Iss 8, Pp n/a-n/a (2019)

Subject Terms: MYO15A, next‐generation sequencing, nonsyndromic hearing loss, OTOF, RDX, Genetics, QH426-470

File Description: electronic resource

Relation: https://doaj.org/toc/2324-9269

Access URL: https://doaj.org/article/075ed0ab33c3456daa21316f9463d1bb

Screening of DFNB3 in Iranian families with autosomal recessive non-syndromic hearing loss reveals a novel pathogenic mutation in the MyTh4 domain of the MYO15A gene in a linked family

Authors: Somayeh Reiisi, Mohammad Amin Tabatabaiefar, Mohammad Hosein Sanati, Morteza Hashemzadeh Chaleshtori

Source: Iranian Journal of Basic Medical Sciences, Vol 19, Iss 7, Pp 772-778 (2016)

Subject Terms: Hearing loss, Iran, Linkage analysis, MYO15A, mutation, Medicine

File Description: electronic resource

Relation: http://ijbms.mums.ac.ir/article_7363_1cee96cbc2302edcc7811babbe37fdfe.pdf; https://doaj.org/toc/2008-3866; https://doaj.org/toc/2008-3874

Access URL: https://doaj.org/article/ac64cd331f44480db0c7d94a0a1a9c8f