Long-term hypoxic atmosphere enhances the stemness, immunoregulatory functions, and therapeutic application of human umbilical cord mesenchymal stem cells

Authors: Qi-Ming Huang, You-Qiong Zhuo, Zhong-Xin Duan, Yin-lin Long, Jia-Nan Wang, Zhou-hang Zhang, Shao-Yong Fan, Yong-Ming Huang, Ke-Yu Deng, Hong-Bo Xin

Source: Bone & Joint Research, Vol 13, Iss 12, Pp 764-778 (2024)

Subject Terms: mesenchymal stem cells, hypoxia, osteoarthritis, mesenchymal stem cells (mscs), chondrocytes, mice model, transplantations, mmp-13, apoptosis, osteoarthritis (oa), cartilage damage, swelling, Diseases of the musculoskeletal system, RC925-935

File Description: electronic resource

Relation: https://doaj.org/toc/2046-3758

Access URL: https://doaj.org/article/f441f8a927c148caad96beb005ed96a6

The level of IL-12, IL-10, IL-4, and MMP-13 in cutaneous leishmaniasis patients

Authors: Abrar Kareem Dhari, Ali Mohammed Abed, Suha Maher Abed

Source: Medical Journal of Babylon, Vol 21, Iss Suppl 2, Pp S244-S249 (2024)

Subject Terms: cutaneous leishmaniasis, il-10, il-12, il-4, human matrix metalloproteinase-13 (mmp-13), Medicine

File Description: electronic resource

Relation: https://doaj.org/toc/1812-156X; https://doaj.org/toc/2312-6760

Access URL: https://doaj.org/article/4ba6a3d864024bb99a05e96e75eccdcc

The role of circulating neutrophils in the progression of kidney cancer

Authors: I. R. Magdieva, T. V. Abakumova, D. R. Dolgova, O. Y. Gorshkov, T. P. Gening

Source: Успехи молекулярной онкологии, Vol 11, Iss 1, Pp 99-104 (2024)

Subject Terms: circulating neutrophils, kidney cancer, angiogenesis, ngal, vegf-a, mmp-13, Neoplasms. Tumors. Oncology. Including cancer and carcinogens, RC254-282

File Description: electronic resource

Relation: https://umo.abvpress.ru/jour/article/view/652; https://doaj.org/toc/2313-805X; https://doaj.org/toc/2413-3787

Access URL: https://doaj.org/article/d55becc537c64e2b9fa1e5edfd58fa96

Basic Fibroblast Growth Factor Induces Matrix Metalloproteinase-13 via ERK MAP Kinase-Altered Phosphorylation and Sumoylation of Elk-1 in Human Adult Articular Chondrocytes [Expression of Concern]

Authors: Sampen HJI, Sharrocks AD, Lin X, Yan D, Kim, van Wijnen A, Hipskind R

Source: Open Access Rheumatology: Research and Reviews, Vol Volume 16, Pp 87-88 (2024)

Subject Terms: osteoarthritis, mmp-13, bfgf, sumo, elk-1, Diseases of the musculoskeletal system, RC925-935

File Description: electronic resource

Relation: https://www.dovepress.com/eoc-basic-fibroblast-growth-factor-induces-matrix-metalloproteinase-13-peer-reviewed-fulltext-article-OARRR; https://doaj.org/toc/1179-156X

Access URL: https://doaj.org/article/b2b9a29e1cd6450284ed52f8715d36f3

Osteoarthritis: From Molecular Pathways to Therapeutic Advances

Contributors: Veronese, Nicola

Subject Terms: osteoarthritis, cartilage, type II collagen, matrix metalloproteinases, MMP-13, regulation, inhibitor, NO synthase, Interleukin-1β, chondrocytes, mitochondrial dysfunction, mesenchimal stem cells, chondrocytic commitment, autophagy, miRNAs, hydrostatic pressure, adipokines, visfatin, Wnt/β-catenin, mechanical loading, obesity, microRNA, oxidative stress, vibrational spectroscopy, near-infrared spectroscopy, infrared spectroscopy, Raman spectroscopy, early diagnosis, exercise, physical activity, nutraceuticals, dietary supplements, inflammation, aging, inflammaging, osteochondral explant culture, joint modelling, pharmacological assay, native tissue analysis, hexosamine biosynthetic pathway, cartilage trauma, post-traumatic osteoarthritis, O-GlcNAcylation, glucosamine, cell death, therapy, sex as a biological variable, whole transcriptome sequencing, molecules, TGF-β, SMAD2/3 signaling, linker modifications, meniscus, proteomics, MRM, ECM, celecoxib, glucosamine sulfate, chondroprotection, NF-κB, cytokines, chemokines, pathogenesis, biomarker, chondrocyte, IL-1β, IFNγ, IL-17, IL-4, RNA-Seq, hypertrophy, remodeling, angiogenesis, chondroitin, collagen, methylsulfonylmethane, vitamin C, vitamin D, hyaluronic acid, Research and information: general, Biology, life sciences

File Description: image/jpeg

Access URL: https://directory.doabooks.org/handle/20.500.12854/81115
https://mdpi.com/books/pdfview/book/5144

Evaluation of the Effect of Phytocomplex on Chondroprotective Biomarkers in an Experimental Model of Osteoarthritis in Rats

Authors: Shridhar PANDYA, Chetan SAVALIYA, Dheeraj NAGORE, Vaishali UNDALE, Shubhada KHADE, Nishant MANTE

Source: Modern Medicine, Vol 29, Iss 4, Pp 329-337 (2022)

Subject Terms: osteoarthritis, mmp-13 (matrix metalloproteinase), comp (cartilage oligomeric matrix protein), chondrocytes regeneration, Medicine, Medicine (General), R5-920

File Description: electronic resource

Relation: https://medicinamoderna.ro/wp-content/uploads/2022/12/Evaluation-of-the-Effect-of-Phytocomplex-on-Chondroprotective-Biomarkers-in-an-Experimental-Model-of-Osteoarthritis-in-Rats.pdf; https://doaj.org/toc/1223-0472; https://doaj.org/toc/2360-2473

Access URL: https://doaj.org/article/ecab60c308824d8c9dee2ed5e63786ed

Effects of swimming exercise and RLN2 induction on relaxin levels, MMP-13, TGFβ expression in the pubic cartilage of pregnant rats

Authors: Ika Oktaviani, Titin Andri Wihastuti, Bambang Rahardjo, Endang Sri Wahyuni, Bilqisthi Ari Putra

Source: Journal of Pharmacy & Pharmacognosy Research, Vol 10, Iss 3, Pp 406-417 (2022)

Subject Terms: mmp-13, pregnant rat, pubic cartilage, relaxin, swimming exercise, tgfβ, Therapeutics. Pharmacology, RM1-950, Pharmacy and materia medica, RS1-441

File Description: electronic resource

Relation: https://jppres.com/jppres/pdf/vol10/jppres21.1317_10.3.406.pdf; https://doaj.org/toc/0719-4250

Access URL: https://doaj.org/article/013852dfed294e6bbd6db33a6caad65f

Ononin ameliorates inflammation and cartilage degradation in rat chondrocytes with IL-1β-induced osteoarthritis by downregulating the MAPK and NF-κB pathways

Authors: Fang Xu, Liang-Jun Zhao, Ting Liao, Zhao-Cong Li, Lei-Lei Wang, Pan-Yu Lin, Rui Jiang, Qing-Jun Wei

Source: BMC Complementary Medicine and Therapies, Vol 22, Iss 1, Pp 1-11 (2022)

Subject Terms: Ononin, Osteoarthritis, Chondrocyte, Inflammation, MMP-13, Collagen II, Other systems of medicine, RZ201-999

File Description: electronic resource

Relation: https://doaj.org/toc/2662-7671

Access URL: https://doaj.org/article/4c3f0ae1027544dea3c5c8edcacc13fc

Suramin attenuates intervertebral disc degeneration by inhibiting NF-κB signalling pathway

Authors: Zi-Miao Liu, Cheng-Chang Lu, Po-Chih Shen, Shih-Hsiang Chou, Chia-Lung Shih, Jian-Chih Chen, Yin Chun Tien

Source: Bone & Joint Research, Vol 10, Iss 8, Pp 498-513 (2021)

Subject Terms: suramin, intervertebral disc degeneration, nf-κb, apoptosis, inflammation, western blotting, cytokines, il-8, aggrecan, mmp-13, matrix metalloproteinases-3, adamts-5, adamts-4, Diseases of the musculoskeletal system, RC925-935

File Description: electronic resource

Relation: https://doaj.org/toc/2046-3758

Access URL: https://doaj.org/article/36947aef69fb4603a6d53a3711ae97bb

Periostin loss-of-function protects mice from post-traumatic and age-related osteoarthritis

Authors: Mukundan Attur, Xin Duan, Lei Cai, Tianzhen Han, Weili Zhang, Eric D. Tycksen, Jonathan Samuels, Robert H. Brophy, Steven B. Abramson, Muhammad Farooq Rai

Source: Arthritis Research & Therapy, Vol 23, Iss 1, Pp 1-14 (2021)

Subject Terms: Periostin, Knee osteoarthritis, Trauma, Aging, MMP-13, RNA-seq, Diseases of the musculoskeletal system, RC925-935

File Description: electronic resource

Relation: https://doaj.org/toc/1478-6362

Access URL: https://doaj.org/article/539326da7b6e4804afcdfd7eb108f332

The relationship between abnormal Core binding factor-β expression in human cartilage and osteoarthritis

Authors: Guangdi Li, Mi Zhang, Yuan Huang, Jiafei Yang, Lianghong Dong, Hao Shi, Long Li, Riguang Liu, Jiangwei Li

Source: BMC Musculoskeletal Disorders, Vol 22, Iss 1, Pp 1-13 (2021)

Subject Terms: Core binding factor-β, Osteoarthritis, MMP-13, IL-1beta, COMP, Diseases of the musculoskeletal system, RC925-935

File Description: electronic resource

Relation: https://doaj.org/toc/1471-2474

Access URL: https://doaj.org/article/948309a2eb844a2bb809bfd5705819cc

Inhibition of hypertrophy and improving chondrocyte differentiation by MMP-13 inhibitor small molecule encapsulated in alginate-chondroitin sulfate-platelet lysate hydrogel

Authors: Shahrbanoo Jahangir, David Eglin, Naomi Pötter, Mojtaba Khozaei Ravari, Martin J. Stoddart, Ali Samadikuchaksaraei, Mauro Alini, Mohammadreza Baghaban Eslaminejad, Majid Safa

Source: Stem Cell Research & Therapy, Vol 11, Iss 1, Pp 1-17 (2020)

Subject Terms: Chondrocyte hypertrophy, Platelet lysate, MMP-13 inhibitor, Small molecules, And mechanical properties, Medicine (General), R5-920, Biochemistry, QD415-436

File Description: electronic resource

Relation: http://link.springer.com/article/10.1186/s13287-020-01930-1; https://doaj.org/toc/1757-6512

Access URL: https://doaj.org/article/65ea2dd0dcf54127a422cdcd47a7e3dc

Resveratrol alleviates the interleukin-1β-induced chondrocytes injury through the NF-κB signaling pathway

Authors: Hong Yi, Wei Zhang, Zhi-Ming Cui, Sheng-Yu Cui, Jian-Bo Fan, Xin-Hui Zhu, Wei Liu

Source: Journal of Orthopaedic Surgery and Research, Vol 15, Iss 1, Pp 1-9 (2020)

Subject Terms: Osteoarthritis, Resveratrol, MMP-3, MMP-13, MMP-1, NF-κB signaling pathway, Orthopedic surgery, RD701-811, Diseases of the musculoskeletal system, RC925-935

File Description: electronic resource

Relation: http://link.springer.com/article/10.1186/s13018-020-01944-8; https://doaj.org/toc/1749-799X

Access URL: https://doaj.org/article/bc01f83d0974482e8942a2a9abdb3cf0

MiR-21-5p regulates extracellular matrix degradation and angiogenesis in TMJOA by targeting Spry1

Authors: Shixing Ma, Aobo Zhang, Xiaole Li, Shizhou Zhang, Shaopeng Liu, Haoming Zhao, Shichao Wu, Lei Chen, Chuan Ma, Huaqiang Zhao

Source: Arthritis Research & Therapy, Vol 22, Iss 1, Pp 1-17 (2020)

Subject Terms: miR-21-5p, Spry1, TMJOA, VEGF, MMP-13, ERK-MAPK signalling pathway, Diseases of the musculoskeletal system, RC925-935

File Description: electronic resource

Relation: http://link.springer.com/article/10.1186/s13075-020-2145-y; https://doaj.org/toc/1478-6362

Access URL: https://doaj.org/article/386a1756fe544202b4d2804a75a00a85

ERα-Targeting PROTAC as a Chemical Knockdown Tool to Investigate the Estrogen Receptor Function in Rat Menopausal Arthritis

Authors: Li Duan, Xiao Xu, Limei Xu, Caining Wen, Kan Ouyang, Zigang Li, Yujie Liang

Source: Frontiers in Pharmacology, Vol 12 (2021)

Subject Terms: PROTACs, estrogen receptor α, MMP-13, articular cartilage metabolism, menopausal arthritis, Therapeutics. Pharmacology, RM1-950

File Description: electronic resource

Relation: https://www.frontiersin.org/articles/10.3389/fphar.2021.764154/full; https://doaj.org/toc/1663-9812

Access URL: https://doaj.org/article/d450ca4837e340d995e0a2b61ba8edd1

Evaluation of ALK5 and MMP13 Expression in the Cartilage Tissue of Rats with Osteoarthritis Rats and Effects of Exercise Training, Ozone and Mesenchymal Stem Cell Therapies on Expression of these Genes

Authors: Samira Oladazimi, parvin farzanegi, Mohammad Ali Azarbayejani

Source: Medical Laboratory Journal, Vol 14, Iss 1, Pp 50-56 (2020)

Subject Terms: osteoarthritis, o3, mscs, exercise, mmp-13, alk5., Medicine

File Description: electronic resource

Relation: http://mlj.goums.ac.ir/article-1-1171-en.html; https://doaj.org/toc/2538-4449

Access URL: https://doaj.org/article/69c175507fcc4ebc9f328d00a7703e14

Proinflammatory cytokines and lipopolysaccharides up regulate MMP-3 and MMP-13 production in Asian elephant (Elephas maximus) chondrocytes: attenuation by anti-arthritic agents

Authors: Nutnicha Sirikaew, Siriwadee Chomdej, Siriwan Tangyuenyong, Weerapongse Tangjitjaroen, Chaleamchat Somgird, Chatchote Thitaram, Siriwan Ongchai

Source: BMC Veterinary Research, Vol 15, Iss 1, Pp 1-13 (2019)

Subject Terms: Elephas maximus, Osteoarthritis, Proinflammatory cytokines, MMP-3, MMP-13, Veterinary medicine, SF600-1100

File Description: electronic resource

Relation: http://link.springer.com/article/10.1186/s12917-019-2170-8; https://doaj.org/toc/1746-6148

Access URL: https://doaj.org/article/61bf9676b099441a9ef64a7a3e0f24fe

The effects of morus nigra on the alveolar bone loss in experimentally-induced periodontitis

Authors: Elif Erdem, Nalan Kaya, Can Ayhan Kaya, Tahir Karaman, Alihan Bozoglan, Neval Di̇ldes, Gonca Ozan, Tuba Talo Yi̇ldi̇ri̇m

Source: European Oral Research, Vol 53, Iss 3, Pp 99-105 (2019)

Subject Terms: experimental periodontitis, cytokines, mmp-8, mmp-13, morus nigra, Dentistry, RK1-715

File Description: electronic resource

Relation: https://dergipark.org.tr/tr/pub/eor/issue/58126/807476; https://doaj.org/toc/2630-6158; https://doaj.org/toc/2651-2823

Access URL: https://doaj.org/article/35bbffcff1a64cefb99ec838215a19e1

The effects of morus nigra on the alveolar bone loss in experimentally-induced periodontitis

Authors: Gonca Ozan, Serkan Dundar, Alihan Bozoglan, Tahir Karaman, Neval Dildes, Can Ayhan Kaya, Nalan Kaya, Elif Erdem

Source: European Oral Research, Vol 53, Iss 3, Pp 99-105 (2019)

Subject Terms: Experimental periodontitis, cytokines, MMP-8, MMP-13, morus nigra, Dentistry, RK1-715

File Description: electronic resource

Relation: https://cdn.istanbul.edu.tr/file/1CD58DF90A/1C8679317DE842368F083ABE4E6CA452?doi=10.26650/eor.20190021; https://doaj.org/toc/2630-6158; https://doaj.org/toc/2651-2823

Access URL: https://doaj.org/article/468e443443834bb0bb922bb845fc326e

Natural Compounds: Potential Therapeutics for the Inhibition of Cartilage Matrix Degradation in Osteoarthritis

Authors: Omer S. Ashruf, Mohammad Yunus Ansari

Source: Life, Vol 13, Iss 1, p 102 (2022)

Subject Terms: natural compounds, polyphenols, cartilage matrix, cartilage homeostasis, MMP-13, ADAMTS5, Science

File Description: electronic resource

Relation: https://www.mdpi.com/2075-1729/13/1/102; https://doaj.org/toc/2075-1729

Access URL: https://doaj.org/article/f9d51805fe004b78b0ee374618de4911