A single-dose MCMV-based vaccine elicits long-lasting immune protection in mice against distinct SARS-CoV-2 variants

Authors: Kristin Metzdorf, Henning Jacobsen, Yeonsu Kim, Luiz Gustavo Teixeira Alves, Upasana Kulkarni, Maja Cokarić Brdovčak, Jelena Materljan, Kathrin Eschke, M. Zeeshan Chaudhry, Markus Hoffmann, Federico Bertoglio, Maximilian Ruschig, Michael Hust, Marko Šustić, Astrid Krmpotić, Stipan Jonjić, Marek Widera, Sandra Ciesek, Stefan Pöhlmann, Markus Landthaler, Luka Čičin-Šain

Source: Frontiers in Immunology, Vol 15 (2024)

Subject Terms: SARS-CoV-2, COVID-19, MCMV, vaccination, single-dose, long-lasting protection, Immunologic diseases. Allergy, RC581-607

File Description: electronic resource

Relation: https://www.frontiersin.org/articles/10.3389/fimmu.2024.1383086/full; https://doaj.org/toc/1664-3224

Access URL: https://doaj.org/article/ff2f6e1930ef4cf194f3fd3eb6aefaa4

Decidual-tissue-resident memory T cells protect against nonprimary human cytomegalovirus infection at the maternal-fetal interface

Authors: Or Alfi, Mevaseret Cohen, Shikma Bar-On, Tamar Hashimshony, Lorinne Levitt, Yael Raz, Yair Blecher, M. Zeeshan Chaudhry, Luka Cicin-Sain, Rina Ben-El, Esther Oiknine-Djian, Tamar Lahav, Olesya Vorontsov, Adiel Cohen, Zichria Zakay-Rones, Leonor Daniel, Michael Berger, Yael Mandel-Gutfreund, Amos Panet, Dana G. Wolf

Source: Cell Reports, Vol 43, Iss 2, Pp 113698- (2024)

Subject Terms: CP: Immunology, Biology (General), QH301-705.5

File Description: electronic resource

Relation: http://www.sciencedirect.com/science/article/pii/S2211124724000263; https://doaj.org/toc/2211-1247

Access URL: https://doaj.org/article/f160aefb25f44da1a6a220ec805efbce

A SARS-CoV-2 neutralizing antibody selected from COVID-19 patients binds to the ACE2-RBD interface and is tolerant to most known RBD mutations

Authors: Federico Bertoglio, Viola Fühner, Maximilian Ruschig, Philip Alexander Heine, Leila Abassi, Thomas Klünemann, Ulfert Rand, Doris Meier, Nora Langreder, Stephan Steinke, Rico Ballmann, Kai-Thomas Schneider, Kristian Daniel Ralph Roth, Philipp Kuhn, Peggy Riese, Dorina Schäckermann, Janin Korn, Allan Koch, M. Zeeshan Chaudhry, Kathrin Eschke, Yeonsu Kim, Susanne Zock-Emmenthal, Marlies Becker, Margitta Scholz, Gustavo Marçal Schmidt Garcia Moreira, Esther Veronika Wenzel, Giulio Russo, Hendrikus S.P. Garritsen, Sebastian Casu, Andreas Gerstner, Günter Roth, Julia Adler, Jakob Trimpert, Andreas Hermann, Thomas Schirrmann, Stefan Dübel, André Frenzel, Joop Van den Heuvel, Luka Čičin-Šain, Maren Schubert, Michael Hust

Source: Cell Reports, Vol 36, Iss 4, Pp 109433- (2021)

Subject Terms: SARS-CoV-2, RBD, spike protein, neutralizing antibody, recombinant antibody, phage display, Biology (General), QH301-705.5

File Description: electronic resource

Relation: http://www.sciencedirect.com/science/article/pii/S2211124721008500; https://doaj.org/toc/2211-1247

Access URL: https://doaj.org/article/9c2876f60a3849cc9e53afa0c2d3362e

ORFeome Phage Display Reveals a Major Immunogenic Epitope on the S2 Subdomain of SARS-CoV-2 Spike Protein

Authors: Rico Ballmann, Sven-Kevin Hotop, Federico Bertoglio, Stephan Steinke, Philip Alexander Heine, M. Zeeshan Chaudhry, Dieter Jahn, Boas Pucker, Fausto Baldanti, Antonio Piralla, Maren Schubert, Luka Čičin-Šain, Mark Brönstrup, Michael Hust, Stefan Dübel

Source: Viruses, Vol 14, Iss 6, p 1326 (2022)

Subject Terms: phage display, epitope mapping, COVID-19, genomic library, NGS, Microbiology, QR1-502

File Description: electronic resource

Relation: https://www.mdpi.com/1999-4915/14/6/1326; https://doaj.org/toc/1999-4915

Access URL: https://doaj.org/article/aadd3be5d75441b3b13f8e9dfa31b510

UL36 Rescues Apoptosis Inhibition and In vivo Replication of a Chimeric MCMV Lacking the M36 Gene

Authors: M. Zeeshan Chaudhry, Bahram Kasmapour, Carlos Plaza-Sirvent, Milica Bajagic, Rosaely Casalegno Garduño, Lisa Borkner, Tihana Lenac Roviš, Andrea Scrima, Stipan Jonjic, Ingo Schmitz, Luka Cicin-Sain

Source: Frontiers in Cellular and Infection Microbiology, Vol 7 (2017)

Subject Terms: cytomegalovirus, apoptosis, UL36, M36, Transgenic virus, Microbiology, QR1-502

File Description: electronic resource

Relation: http://journal.frontiersin.org/article/10.3389/fcimb.2017.00312/full; https://doaj.org/toc/2235-2988

Access URL: https://doaj.org/article/51864234265d4b67ad931786a61dbbf0

NFAT signaling is indispensable for persistent memory responses of MCMV-specific CD8+ T cells.

Authors: M Zeeshan Chaudhry, Lisa Borkner, Upasana Kulkarni, Friederike Berberich-Siebelt, Luka Cicin-Sain

Source: PLoS Pathogens, Vol 20, Iss 2, p e1012025 (2024)

Subject Terms: Immunologic diseases. Allergy, RC581-607, Biology (General), QH301-705.5

File Description: electronic resource

Relation: https://journals.plos.org/plospathogens/article/file?id=10.1371/journal.ppat.1012025&type=printable; https://doaj.org/toc/1553-7366; https://doaj.org/toc/1553-7374

Access URL: https://doaj.org/article/0eb04c2d77ee4f83a07608ad30411962