Evaluation of lithium chloride safety and toxicokinetics for injection in minipigs

Authors: V. M. Kosman, A. Yu. Romanenko, M. V. Karlina, N. M. Faustova, E. V. Mazukina, A. N. Kuzovlev, A. V. Grechko, R. A. Cherpakov, M. N. Makarova, V. G. Makarov

Source: Сибирский научный медицинский журнал, Vol 44, Iss 6, Pp 114-127 (2025)

Subject Terms: lithium chloride, repeated intravenous injection, toxicity, local tolerability, bioanalytical assay, serum, colorimetric method with quinizarin, Medicine

File Description: electronic resource

Relation: https://sibmed.elpub.ru/jour/article/view/1839; https://doaj.org/toc/2410-2512; https://doaj.org/toc/2410-2520

Access URL: https://doaj.org/article/be5f6ededffa4ef2bb219aabcf1d2daa

Comparative Preclinical Evaluation of the Safety, Antifungal Activity, and Pharmacokinetics of Sertaconazole Products for External Use

Authors: V. M. Kosman, M. V. Karlina, V. A. Vavilova, K. E. Borovkova, K. L. Kryshen, N. V. Marchenko, S. A. Kopatko, I. V. Sychkova, D. R. Kargopoltseva, M. N. Makarova, V. G. Makarov

Source: Безопасность и риск фармакотерапии, Vol 12, Iss 1, Pp 83-98 (2024)

Subject Terms: sertaconazole, shampoo, solution, topical application, pharmacokinetics, preclinical studies, safety study, rats, antifungal activity, Therapeutics. Pharmacology, RM1-950

File Description: electronic resource

Relation: https://www.risksafety.ru/jour/article/view/358; https://doaj.org/toc/2312-7821; https://doaj.org/toc/2619-1164

Access URL: https://doaj.org/article/005982f3fa524854ac95cc9d897c54e7

Comparison of pharmacokinetic parameters calculation techniques in studies with animal-point design

Authors: V. M. Kosman, M. V. Karlina, M. N. Makarоva, V. G. Makarov

Source: Фармакокинетика и Фармакодинамика, Vol 0, Iss 3, Pp 19-27 (2023)

Subject Terms: pharmacokinetics, rats, animal per time point design, parameters calculation, Pharmacy and materia medica, RS1-441

File Description: electronic resource

Relation: https://www.pharmacokinetica.ru/jour/article/view/378; https://doaj.org/toc/2587-7836; https://doaj.org/toc/2686-8830

Access URL: https://doaj.org/article/30a5629eddf1451b8a9092f76db7c766

Preclinical Evaluation of Esomeprazole Safety and Toxicokinetics

Authors: V. M. Kosman, M. V. Karlina, E. V. Mazukina, A. A. Globenko, E. A. Jain, M. N. Makarova, V. G. Makarov

Source: Безопасность и риск фармакотерапии, Vol 11, Iss 2, Pp 176-190 (2023)

Subject Terms: esomeprazole, nexium, proton pump inhibitors, safety, toxicokinetics, preclinical studies, Therapeutics. Pharmacology, RM1-950

File Description: electronic resource

Relation: https://www.risksafety.ru/jour/article/view/342; https://doaj.org/toc/2312-7821; https://doaj.org/toc/2619-1164

Access URL: https://doaj.org/article/4ff69e0a81ad4e8e9858ccb8df76c723

The Interconnection Between Pharmaceutical Development and Preclinical Research (Review)

Authors: I. N. Ampilogova, M. V. Karlina, V. G. Makarov, M. N. Makarova

Source: Разработка и регистрация лекарственных средств, Vol 12, Iss 2, Pp 155-163 (2023)

Subject Terms: pharmaceutical development, preclinical studies, quality by design, traditional development, improved approach, Pharmaceutical industry, HD9665-9675

File Description: electronic resource

Relation: https://www.pharmjournal.ru/jour/article/view/1495; https://doaj.org/toc/2305-2066; https://doaj.org/toc/2658-5049

Access URL: https://doaj.org/article/1369a2d9dddd406e8e86b38b08a7c1c4

Neuraminidase Inhibitors: Development and Validation of a Procedure for In Vitro Determination of the Inhibitory Effect

Authors: N. M. Faustova, S. S. Petlitskaya, I. N. Ampilogova, M. V. Karlina, M. N. Makarova, V. G. Makarov

Source: Регуляторные исследования и экспертиза лекарственных средств, Vol 13, Iss 1, Pp 60-76 (2023)

Subject Terms: neuraminidase, oseltamivir, zanamivir hydrate, inhibitory effect, 2-hydroxypropyl-β-cyclodextrin, bisnaphthazarin, Medicine (General), R5-920

File Description: electronic resource

Relation: https://www.vedomostincesmp.ru/jour/article/view/466; https://doaj.org/toc/3034-3062; https://doaj.org/toc/3034-3453

Access URL: https://doaj.org/article/2a9e3bd608224f3e8433f0fb374c3e13

Considerations for the Bioanalytical Part of Equivalence Studies of Biosimilar Nadroparin Calcium

Authors: V. M. Kosman, M. V. Karlina, N. M. Faustova, E. A. Ezhova, I. G. Kotelnikova, V. G. Makarov, M. N. Makarova

Source: Регуляторные исследования и экспертиза лекарственных средств, Vol 13, Iss 1, Pp 89-103 (2023)

Subject Terms: comparative pharmacodynamics, biosimilar medicinal product, nadroparin calcium, single subcutaneous administration, low molecular weight heparins, anti-xa activity, anti-iia activity, tissue factor pathway inhibitor, surrogate pharmacokinetic markers, Medicine (General), R5-920

File Description: electronic resource

Relation: https://www.vedomostincesmp.ru/jour/article/view/406; https://doaj.org/toc/3034-3062; https://doaj.org/toc/3034-3453

Access URL: https://doaj.org/article/a8e1acb6678b42c1a694bf109e9783b8

Pharmacokinetic Interactions of Phenosanic Acid with Valproic Acid and Carbamazepine in Dogs

Authors: M. V. Karlina, V. M. Kosman, V. G. Makarov, M. N. Makarova, S. V. Morozov, E. E. Gushchina, N. V. Zhuravskaya

Source: Безопасность и риск фармакотерапии, Vol 10, Iss 4, Pp 420-433 (2022)

Subject Terms: pharmacokinetic drug interaction, phenosanic acid, valproic acid, carbamazepine, hplc-uv, blood plasma, dogs, preclinical studies, Therapeutics. Pharmacology, RM1-950

File Description: electronic resource

Relation: https://www.risksafety.ru/jour/article/view/288; https://doaj.org/toc/2312-7821; https://doaj.org/toc/2619-1164

Access URL: https://doaj.org/article/17d04b462e3c43f9845b1c8465b789c8

Use of Biomarkers in Pharmacokinetics Studies of Medicinal Products of Natural Origin

Authors: V. M. Kosman, N. M. Faustova, M. V. Karlina, V. G. Makarov, M. N. Makarova

Source: Регуляторные исследования и экспертиза лекарственных средств, Vol 11, Iss 1, Pp 24-35 (2021)

Subject Terms: pharmacokinetics, medicinal products of natural origin, biological activity, biomarkers, anti-factor xa, dipeptidyl peptidase 4, lactate dehydrogenase, enzymatic assay, kinetic methods, fucoidan, fucus vesiculosus, biologically active compounds, glycosylated polypeptide, strongylocentrotus droebachiensis, Medicine (General), R5-920

File Description: electronic resource

Relation: https://www.vedomostincesmp.ru/jour/article/view/349; https://doaj.org/toc/3034-3062; https://doaj.org/toc/3034-3453

Access URL: https://doaj.org/article/58dcd174adc948b0a1a8060784d9ee58

Effect of Sample Preparation and Chromatographic Conditions on Background Signal

Authors: V. M. Kosman, M. V. Karlina, O. N. Pozharitskaya

Source: Регуляторные исследования и экспертиза лекарственных средств, Vol 10, Iss 2, Pp 121-128 (2020)

Subject Terms: hplc-uv, blood plasma, sample preparation, precipitation agent, chromatographic mode, bioanalytical methods, Medicine (General), R5-920

File Description: electronic resource

Relation: https://www.vedomostincesmp.ru/jour/article/view/292; https://doaj.org/toc/3034-3062; https://doaj.org/toc/3034-3453

Access URL: https://doaj.org/article/216f76600d9849469de57595eac1c194

DETERMINATION OF DARBEPOETIN ALFA IN RABBIT PLASMA BY ELISA

Authors: M. V. Karlina, N. M. Faustova, O. N. Pozharitskaya, V. M. Kosman, V. G. Makarov, A. N. Shikov

Source: Разработка и регистрация лекарственных средств, Vol 0, Iss 4, Pp 204-210 (2019)

Subject Terms: darbepoetin, elisa, validation, pharmacokinetics, rabbits, plasma, Pharmaceutical industry, HD9665-9675

File Description: electronic resource

Relation: https://www.pharmjournal.ru/jour/article/view/176; https://doaj.org/toc/2305-2066; https://doaj.org/toc/2658-5049

Access URL: https://doaj.org/article/8906641558e44be6aafcf57756e55aba