Guselkumab binding to CD64+ IL-23–producing myeloid cells enhances potency for neutralizing IL-23 signaling

Authors: Kacey L. Sachen, Deepa Hammaker, Indra Sarabia, Brian Stoveken, John Hartman, Kristin L. Leppard, Nicholas A. Manieri, Phuc Bao, Carrie Greving, Eilyn R. Lacy, Matthew DuPrie, Joshua Wertheimer, Janise D. Deming, Joseph Brown, Amy Hart, He (Hurley) Li, Tom C. Freeman, Brice Keyes, Kristen Kohler, Ian White, Nathan Karpowich, Ruth Steele, M. Merle Elloso, Steven Fakharzadeh, Kavitha Goyal, Frédéric Lavie, Maria T. Abreu, Matthieu Allez, Raja Atreya, Robert Bissonnette, Kilian Eyerich, James G. Krueger, Dennis McGonagle, Iain B. McInnes, Christopher Ritchlin, Anne M. Fourie

Source: Frontiers in Immunology, Vol 16 (2025)

Subject Terms: IL-23, IL-23p19 subunit inhibitors, guselkumab, risankizumab, CD64, in vitro cellular assays, Immunologic diseases. Allergy, RC581-607

File Description: electronic resource

Relation: https://www.frontiersin.org/articles/10.3389/fimmu.2025.1532852/full; https://doaj.org/toc/1664-3224

Access URL: https://doaj.org/article/8bdb8bc0ba1c48b187aee2e41e087d7f

IL-23 past, present, and future: a roadmap to advancing IL-23 science and therapy

Authors: James G. Krueger, Kilian Eyerich, Vijay K. Kuchroo, Christopher T. Ritchlin, Maria T. Abreu, M. Merle Elloso, Anne Fourie, Steven Fakharzadeh, Jonathan P. Sherlock, Ya-Wen Yang, Daniel J. Cua, Iain B. McInnes

Source: Frontiers in Immunology, Vol 15 (2024)

Subject Terms: IL-23, cytokine, immune-mediated inflammatory diseases, psoriasis, psoriatic arthritis, inflammatory bowel disease, Immunologic diseases. Allergy, RC581-607

File Description: electronic resource

Relation: https://www.frontiersin.org/articles/10.3389/fimmu.2024.1331217/full; https://doaj.org/toc/1664-3224

Access URL: https://doaj.org/article/3fb972d7f9ef4534a189cd8ccc187a46

Suppression of experimental autoimmune encephalomyelitis using estrogen receptor-selective ligands.

Authors: M Merle Elloso, Kristen Phiel, Ruth A Henderson, Heather A Harris, Steven J Adelman

Source: Journal of Endocrinology; May2005, Vol. 185 Issue 2, p243-252, 10p

IL-27 Limits Type 2 Immunopathology Following Parainfluenza Virus Infection.

Authors: Gaia Muallem, Sagie Wagage, Yan Sun, Jonathan H DeLong, Alex Valenzuela, David A Christian, Gretchen Harms Pritchard, Qun Fang, Elizabeth L Buza, Deepika Jain, M Merle Elloso, Carolina B López, Christopher A Hunter

Source: PLoS Pathogens, Vol 13, Iss 1, p e1006173 (2017)

Subject Terms: Immunologic diseases. Allergy, RC581-607, Biology (General), QH301-705.5

File Description: electronic resource

Relation: http://europepmc.org/articles/PMC5305264?pdf=render; https://doaj.org/toc/1553-7366; https://doaj.org/toc/1553-7374

Access URL: https://doaj.org/article/fede9b5bf3fe4e05802f0a6a11661c92