A randomised, double-blind, placebo-controlled trial of repeated nebulisation of non-viral cystic fibrosis transmembrane conductance regulator (CFTR) gene therapy in patients with cystic fibrosis

Authors: Eric WFW Alton, David K Armstrong, Deborah Ashby, Katie J Bayfield, Diana Bilton, Emily V Bloomfield, A Christopher Boyd, June Brand, Ruaridh Buchan, Roberto Calcedo, Paula Carvelli, Mario Chan, Seng H Cheng, David S Collie, Steve Cunningham, Heather E Davidson, Gwyneth Davies, Jane C Davies, Lee A Davies, Maria H Dewar, Ann Doherty, Jackie Donovan, Natalie S Dwyer, Hala I Elgmati, Rosanna F Featherstone, Jemyr Gavino, Sabrina Gea-Sorli, Duncan M Geddes, James SR Gibson, Deborah R Gill, Andrew P Greening, Uta Griesenbach, David M Hansell, Katharine Harman, Tracy E Higgins, Samantha L Hodges, Stephen C Hyde, Laura Hyndman, J Alastair Innes, Joseph Jacob, Nancy Jones, Brian F Keogh, Maria P Limberis, Paul Lloyd-Evans, Alan W Maclean, Michelle C Manvell, Dominique McCormick, Michael McGovern, Gerry McLachlan, Cuixiang Meng, M Angeles Montero, Hazel Milligan, Laura J Moyce, Gordon D Murray, Andrew G Nicholson, Tina Osadolor, Javier Parra-Leiton, David J Porteous, Ian A Pringle, Emma K Punch, Kamila M Pytel, Alexandra L Quittner, Gina Rivellini, Clare J Saunders, Ronald K Scheule, Sarah Sheard, Nicholas J Simmonds, Keith Smith, Stephen N Smith, Najwa Soussi, Samia Soussi, Emma J Spearing, Barbara J Stevenson, Stephanie G Sumner-Jones, Minna Turkkila, Rosa P Ureta, Michael D Waller, Marguerite Y Wasowicz, James M Wilson, Paul Wolstenholme-Hogg, on behalf of the UK Cystic Fibrosis Gene Therapy Consortium

Source: Efficacy and Mechanism Evaluation, Vol 3, Iss 5 (2016)

Subject Terms: cystic fibrosis, gene therapy, liposome, plasmid, clinical trial, randomised controlled trial, cftr, cystic fibrosis transmembrane conductance regulator, Medicine

File Description: electronic resource

Relation: https://doaj.org/toc/2050-4365; https://doaj.org/toc/2050-4373

Access URL: https://doaj.org/article/09b29fe1b155492fba24a177fe4be24c

NTRK Gene Expression in Non-Small-Cell Lung Cancer

Authors: Jair Gutierrez-Herrera, M. Angeles Montero-Fernandez, Georgia Kokaraki, Luigi De Petris, Raul Maia Falcão, Manuel Molina-Centelles, Ricardo Guijarro, Simon Ekman, Cristian Ortiz-Villalón

Source: Journal of Respiration, Vol 5, Iss 1, p 2 (2025)

Subject Terms: predictive biomarkers in non-small-cell lung cancer, NTRK status in tumor cells, whole exome sequencing, WES–NGS, ingenuity pathway analysis (IPA), Internal medicine, RC31-1245, Medicine (General), R5-920

File Description: electronic resource

Relation: https://www.mdpi.com/2673-527X/5/1/2; https://doaj.org/toc/2673-527X

Access URL: https://doaj.org/article/06dedd344a5347758785aa4f53889563

KAP degradation by calpain is associated with CK2 phosphorylation and provides a novel mechanism for cyclosporine A-induced proximal tubule injury.

Authors: Olga Tornavaca, Eduard Sarró, Gloria Pascual, Beatriz Bardaji, M Angeles Montero, M Teresa Salcedo, Maria Plana, Joan López-Hellin, Emilio Itarte, Anna Meseguer

Source: PLoS ONE, Vol 6, Iss 9, p e25746 (2011)

Subject Terms: Medicine, Science

File Description: electronic resource

Relation: http://europepmc.org/articles/PMC3182248?pdf=render; https://doaj.org/toc/1932-6203

Access URL: https://doaj.org/article/ba9429455e464ae4a4261e9e29aa6d92

PD-1 expression in tumor infiltrating lymphocytes as a prognostic marker in early-stage non-small cell lung cancer

Authors: Asaf Dan, Ozan Aricak, Konstantinos Rounis, M. Angeles Montero-Fernandez, Ricardo Guijarro, Simon Ekman, Cristian Ortiz-Villalón, Luigi De Petris

Source: Frontiers in Oncology, Vol 14 (2024)

Subject Terms: early-stage NSCLC, TILs, PD-1, prognosis, immunotherapy, Tissue microarray, Neoplasms. Tumors. Oncology. Including cancer and carcinogens, RC254-282

File Description: electronic resource

Relation: https://www.frontiersin.org/articles/10.3389/fonc.2024.1414900/full; https://doaj.org/toc/2234-943X

Access URL: https://doaj.org/article/6bc2bad02c314212b6aa290293416a85

The UIP/IPF fibroblastic focus is a collagen biosynthesis factory embedded in a distinct extracellular matrix

Authors: Jeremy A. Herrera, Lewis Dingle, M. Angeles Montero, Rajamiyer V. Venkateswaran, John F. Blaikley, Craig Lawless, Martin A. Schwartz

Source: JCI Insight, Vol 7, Iss 16 (2022)

Subject Terms: Pulmonology, Medicine

File Description: electronic resource

Relation: https://doaj.org/toc/2379-3708

Access URL: https://doaj.org/article/da6ce78e6e224d07974ead382256b1a5

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Heterogeneity in extracellular vesicle secretion by single human macrophages revealed by super‐resolution microscopy

Authors: Susanne Dechantsreiter, Ashley R. Ambrose, Jonathan D. Worboys, Joey M. E. Lim, Sylvia Liu, Rajesh Shah, M. Angeles Montero, Anne Marie Quinn, Tracy Hussell, Gillian M. Tannahill, Daniel M. Davis

Source: Journal of Extracellular Vesicles, Vol 11, Iss 4, Pp n/a-n/a (2022)

Subject Terms: class II MHC protein, extracellular vesicles, macrophages, single‐cell analysis, super‐resolution microscopy, Cytology, QH573-671

File Description: electronic resource

Relation: https://doaj.org/toc/2001-3078

Access URL: https://doaj.org/article/b757983969c0432a9dc11231c7a45208