Milk consumption and risk of twelve cancers: A large-scale observational and Mendelian randomisation study

Authors: Lumsden, Amanda L., Mulugeta, Anwar, Hyppönen, Elina

Source: Clinical nutrition. 42(1):1-8

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Metabolic profile‐based subgroups can identify differences in brain volumes and brain iron deposition

Authors: Lumsden, Amanda L., Mulugeta, Anwar, Mäkinen, Ville‐Petteri, Hyppönen, Elina

Source: Diabetes, obesity & metabolism. 25(1):121-131

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Alterations in GLP-1 and PYY release with aging and body mass in the human gut

Authors: Jones, Lauren A. ^a, Sun, Emily W. ^a, Lumsden, Amanda L. ^b, Thorpe, Daniel W. ^a, Peterson, Rochelle A. ^a, De Fontgalland, Dayan ^c, Sposato, Luigi ^c, Rabbitt, Philippa ^c, Hollington, Paul ^c, Wattchow, David A. ^c, Keating, Damien J. ^{a, ∗}

Source: In Molecular and Cellular Endocrinology 1 December 2023 578

Hypothesis‐free discovery of novel cancer predictors using machine learning.

Authors: Madakkatel, Iqbal^1,2 (AUTHOR), Lumsden, Amanda L.^1,2 (AUTHOR), Mulugeta, Anwar^1,2,3 (AUTHOR), Olver, Ian⁴ (AUTHOR), Hyppönen, Elina^1,2 (AUTHOR) elina.hypponen@unisa.edu.au

Source: European Journal of Clinical Investigation. Oct2023, Vol. 53 Issue 10, p1-13. 13p.

Subject Terms: *MACHINE learning, *HDL cholesterol, *STATISTICAL learning, *ERYTHROCYTES, *BODY mass index

Geographic Terms: UNITED Kingdom

A Gut-Intrinsic Melanocortin Signaling Complex Augments L-Cell Secretion in Humans

Authors: Sun, Emily W., Iepsen, Eva W., Pezos, Nektaria, Lumsden, Amanda L., Martin, Alyce M., Schober, Gudrun, Isaacs, Nichole J., Rayner, Christopher K., Nguyen, Nam Q., de Fontgalland, Dayan, Rabbitt, Philippa, Hollington, Paul, Wattchow, David A., Hansen, Torben, Holm, Jens-Christian, Liou, Alice P., Jackson, V. Margaret, Torekov, Signe S., Young, Richard L., Keating, Damien J.

Source: In Gastroenterology August 2021 161(2):536-547

Circulating Phylloquinone and the Risk of Four Female-Specific Cancers: A Mendelian Randomization Study.

Authors: Yalew, Melaku, Mulugeta, Anwar, Lumsden, Amanda L., Madakkatel, Iqbal, Lee, S. Hong, Oehler, Martin K., Mäenpää, Johanna, Hyppönen, Elina

Source: Nutrients; Nov2024, Vol. 16 Issue 21, p3680, 9p

Brief research report: Transcriptional blockade of angiotensin converting enzyme 2 modelled in human retinal pigment epithelial cells.

Authors: Ashander, Liam M., Lumsden, Amanda L., Yuefang Ma, Chun Rong Tan, Alwin, Appukuttan, Binoy, Daniel, Santhosh, Michael, Michael Z., Smith, Justine R.

Source: Frontiers in Drug Discovery; 2024, p01-11, 11p

Apolipoprotein E (APOE) genotype-associated disease risks: a phenome-wide, registry-based, case-control study utilising the UK Biobank

Authors: Lumsden, Amanda L., Mulugeta, Anwar, Zhou, Ang, Hyppönen, Elina

Source: In eBioMedicine September 2020 59

Brief research report: ETS-1 blockade increases ICAM-1 expression in activated human retinal endothelial cells.

Authors: Alwin Chun Rong Tan, Yuefang Ma, Appukuttan, Binoy, Lower, Karen, Lumsden, Amanda L., Michael, Michael Z., Smith, Justine R., Ashander, Liam M.

Source: Frontiers in Ophthalmology; 2024, p1-7, 7p

Phenome‐wide association study of ovarian cancer identifies common comorbidities and reveals shared genetics with complex diseases and biomarkers.

Authors: Mulugeta, Anwar^1,2,3 (AUTHOR) anwarmulugeta.gebremichael@unisa.edu.au, Lumsden, Amanda L.^1,2 (AUTHOR), Madakkatel, Iqbal^1,2 (AUTHOR), Stacey, David^1,2 (AUTHOR), Lee, S. Hong^1,2,4 (AUTHOR), Mäenpää, Johanna^5,6 (AUTHOR), Oehler, Martin K.^7,8 (AUTHOR), Hyppönen, Elina^1,2 (AUTHOR)

Source: Cancer Medicine. Feb2024, Vol. 13 Issue 4, p1-13. 13p.

Subject Terms: *OVARIAN cancer, *GENETICS, *COMORBIDITY, *BIOMARKERS, *OLDER women

Geographic Terms: UNITED Kingdom

Sa1738 – Olorinab (Formerly Apd371), a Peripherally Restricted, Highly Selective, Full Agonist of the Cannabinoid Receptor 2 (CB2), Reduces Visceral Hypersensitivity in Animal Models

Authors: Castro, Joel, Maddern, Jessica, Garcia-Caraballo, Sonia, Lumsden, Amanda L., Lindstrom, Beatriz, Adams, John, Brierley, Stuart

Source: Gastroenterology. 156(6):S-382-S-382

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100080965104.0x000001&indx=1&recIds=ETOCvdc_100080965104.0x000001

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ICAM-1-related long non-coding RNA: promoter analysis and expression in human retinal endothelial cells

Authors: Lumsden, Amanda L., Ma, Yuefang, Ashander, Liam M., Stempel, Andrew J., Keating, Damien J., Smith, Justine R., Appukuttan, Binoy

Source: BMC research notes. 11(1)

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100130438125.0x000001&indx=1&recIds=ETOCvdc_100130438125.0x000001

Healthy Lifestyle, Genetic Risk and Brain Health: A Gene-Environment Interaction Study in the UK Biobank.

Authors: Mulugeta, Anwar, Navale, Shreeya S., Lumsden, Amanda L., Llewellyn, David J., Hyppönen, Elina

Source: Nutrients; Oct2022, Vol. 14 Issue 19, p3907, 13p

Huntingtin-associated protein 1: Eutherian adaptation from a TRAK-like protein, conserved gene promoter elements, and localization in the human intestine.

Authors: Lumsden, Amanda L.¹ amanda.lumsden@flinders.edu.au, Young, Richard L.^2,3, Pezos, Nektaria^2,3, Keating, Damien J.^1,2 damien.keating@flinders.edu.au

Source: BMC Evolutionary Biology. 10/13/2016, Vol. 16, p1-18. 18p.

Subject Terms: *HUNTINGTIN protein, *NERVE tissue proteins, *MARSUPIALS, *KINESIN, *CARRIER proteins, *MULTICELLULAR organisms

Deficiency of Huntingtin Has Pleiotropic Effects in the Social Amoeba Dictyostelium discoideum.

Authors: Myre, Michael A., Lumsden, Amanda L., Thompson, Morgan N., Wasco, Wilma, MacDonald, Marcy E., Gusella, James F.

Source: PLoS Genetics. Apr2011, Vol. 7 Issue 4, p1-26. 26p.

Subject Terms: *AMOEBA, *DICTYOSTELIUM discoideum, *LABORATORY mice, *GENETIC disorders, *CELLULAR signal transduction, *GENETIC regulation, *CYTOLOGY

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Gut Serotonin Is a Regulator of Obesity and Metabolism

Authors: Young, Richard L., Lumsden, Amanda L., Keating, Damien J.

Source: In Gastroenterology July 2015 149(1):253-255