The interplay between acute and late toxicity among patients receiving prostate radiotherapy: an individual patient data meta-analysis of six randomised trials

Authors: Nikitas, John ^{a, v}, Jamshidian, Parsa ^b, Tree, Alison C ^{d, e}, Hall, Emma ^d, Dearnaley, David ^{d, e}, Michalski, Jeff M ^f, Lee, W Robert ^g, Nguyen, Paul L ^h, Sandler, Howard M ⁱ, Catton, Charles N ^j, Lukka, Himanshu R ^k, Incrocci, Luca ^l, Heemsbergen, Wilma ^l, Pos, Floris J ^m, Roy, Soumyajit ^{n, u}, Malone, Shawn ^o, Horwitz, Eric ^p, Wong, Jessica Karen ^p, Arcangeli, Stefano ^q, Sanguineti, Giuseppe ^r, Romero, Tahmineh ^c, Sun, Yilun ^s, Steinberg, Michael L ^a, Valle, Luca F ^{a, t}, Weidhaas, Joanne B ^a, Spratt, Daniel ^s, Telesca, Donatello ^b, Kishan, Amar U ^{a, *}

Source: In The Lancet Oncology March 2025 26(3):378-386

Five-Year Patient-Reported Outcomes in NRG Oncology RTOG 0938, Evaluating Two Ultrahypofractionated Regimens for Prostate Cancer

Authors: Lukka, Himanshu R., Deshmukh, Snehal, Bruner, Deborah W., Bahary, Jean-Paul, Lawton, Colleen A.F., Efstathiou, Jason A., Kudchadker, Rajat J., Ponsky, Lee E., Seaward, Samantha A., Dayes, Ian S., Gopaul, Darindra D., Michalski, Jeff M., Delouya, Guila, Kaplan, Irving D., Horwitz, Eric M., Roach, Mack, Feng, Felix Y., Pugh, Stephanie L., Sandler, Howard M., Kachnic, Lisa A.

Source: International journal of radiation oncology, biology, physics. 116(4):770-778

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100193520620.0x000001&indx=1&recIds=ETOCvdc_100193520620.0x000001

Long-term outcomes and effects of hypofractionated radiotherapy in microinvasive breast cancer: Analysis from a randomized trial

Authors: Goldberg, Mira, Parpia, Sameer, Rakovitch, Eileen, Chang, Lynn, Bowen, Julie, Lukka, Himanshu, Perera, Francisco, Fyles, Anthony, Wright, James, Sussman, Jonathan, Whelan, Timothy

Source: Breast. 68:189-193

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100185812617.0x000001&indx=1&recIds=ETOCvdc_100185812617.0x000001

The addition of androgen deprivation therapy and pelvic lymph node treatment to prostate bed salvage radiotherapy (NRG Oncology/RTOG 0534 SPPORT): an international, multicentre, randomised phase 3 trial

Authors: Pollack, Alan, Karrison, Theodore G, Balogh, Alexander G, Gomella, Leonard G, Low, Daniel A, Bruner, Deborah W, Wefel, Jeffrey S, Martin, Andre-Guy, Michalski, Jeff M, Angyalfi, Steve J, Lukka, Himanshu, Faria, Sergio L, Rodrigues, George B, Beauchemin, Marie-Claude, Lee, R Jeffrey, Seaward, Samantha A, Allen, Aaron M, Monitto, Drew C, Seiferheld, Wendy, Sartor, Oliver, Feng, Felix, Sandler, Howard M

Source: Lancet. 399(10338):1886-1901

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100195809815.0x000001&indx=1&recIds=ETOCvdc_100195809815.0x000001

Biochemical Failure Is Not a Surrogate End Point for Overall Survival in Recurrent Prostate Cancer: Analysis of NRG Oncology/RTOG 9601

Authors: Jackson, William C., Tang, Ming, Schipper, Matthew J., Sandler, Howard M., Zumsteg, Zachary S., Efstathiou, Jason A., Shipley, William U., Seiferheld, Wendy, Lukka, Himanshu R., Bahary, Jean-Paul, Zietman, Anthony L., Pisansky, Thomas M., Zeitzer, Kenneth L., Hall, William A., Dess, Robert T., Lovett, Richard D., Balogh, Alexander G., Feng, Felix Y., Spratt, Daniel E.

Source: Journal of clinical oncology. 40(27):3172-3179

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100171064914.0x000001&indx=1&recIds=ETOCvdc_100171064914.0x000001

Salvage radiotherapy following HiFU: An institutional series and literature review

Authors: Mesci, Aruz, Gouran‐Savadkoohi, Mohammad, Ribeiro, Derek, Dayes, Ian, Lukka, Himanshu, Schnarr, Kara, Quan, Kimmen, Goldberg, Mira, Hallock, Abhirami, Tsakiridis, Theodoros

Source: Journal of medical imaging and radiation oncology. 66(6):847-852

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100159872205.0x000001&indx=1&recIds=ETOCvdc_100159872205.0x000001

Hypofractionated radiotherapy for prostate cancer (HYDRA): An individual patient data meta-analysis of randomized trials in the MARCAP consortium.

Authors: Kishan, Amar Upadhyaya, Sun, Yilun, Dearnaley, David P., Hall, Emma, Tree, Alison, Catton, Charles, Lukka, Himanshu, Lee, William Robert, Sandler, Howard M., Incrocci, Luca, Heemsbergen, Wilma, Wong, Jessica Karen, Horwitz, Eric M., Hoffman, Karen E., Hassanzadeh, Comron, Kuban, Deborah A., Sanguineti, Giuseppe, Arcangeli, Stefano, Nikitas, John, Spratt, Daniel Eidelberg

Source: Journal of Clinical Oncology; 2/20/2025 Supplement 5, Vol. 43, p385-385, 125p

The prognostic impact of prostate-specific antigen at 6 months after post-prostatectomy radiotherapy: An individual patient data analysis of two NRG oncology randomized trials.

Authors: Mohamad, Osama, Swanson, David Michael, Pollack, Alan, Lukka, Himanshu, Dal Pra, Alan, Dayes, Ian S., Martin, Andre-Guy, Greenberg, Michael, Balogh, Alexander G., Michalski, Jeff M., Vavassis, Peter, Currey, Adam D., Dess, Robert Timothy, Efstathiou, Jason A., Kapadia, Nirav S., Patel, Samir, Ahmad, Belal, Sandler, Howard M., Pugh, Stephanie L., Nguyen, Paul L.

Source: Journal of Clinical Oncology; 2/20/2025 Supplement 5, Vol. 43, p254-254, 288p

A Randomized Phase II Trial of Prostate Boost Irradiation With Stereotactic Body Radiotherapy (SBRT) or Conventional Fractionation (CF) External Beam Radiotherapy (EBRT) in Locally Advanced Prostate Cancer: The PBS Trial (NCT03380806)

Authors: Isfahanian, Naghmeh, Lukka, Himanshu, Dayes, Ian, Quan, Kimmen, Schnarr, Kara Lynne, Douvi, Georgia, Goldberg, Mira, Wright, Jim, Swaminath, Anand, Chow, Tom, Diamond, Kevin, Cutz, Jean Claude, Kavsak, Peter, Thabane, Lehana, Tsakiridis, Theodoros

Source: Clinical genitourinary cancer. 18(4):e410-e415

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100117299983.0x000001&indx=1&recIds=ETOCvdc_100117299983.0x000001

Prostate-Specific Antigen After Neoadjuvant Androgen Suppression in Prostate Cancer Patients Receiving Short-Term Androgen Suppression and External Beam Radiation Therapy: Pooled Analysis of Four NRG Oncology Radiation Therapy Oncology Group Randomized Clinical Trials

Authors: Hallemeier, Christopher L., Zhang, Peixin, Pisansky, Thomas M., Hanks, Gerald E., McGowan, David G., Roach, Mack, Zeitzer, Kenneth L., Firat, Selim Y., Husain, Siraj M., D'Souza, David P., Souhami, Luis, Parliament, Matthew B., Rosenthal, Seth A., Lukka, Himanshu R., Rotman, Marvin, Horwitz, Eric M., Miles, Edward F., Paulus, Rebecca, Sandler, Howard M.

Source: International journal of radiation oncology, biology, physics. 104(5):1057-1065

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100142957166.0x000001&indx=1&recIds=ETOCvdc_100142957166.0x000001

Prognostic Impact of Prostate-Specific Antigen at 6 Months After Radiotherapy in Localized Prostate Cancer: An Individual Patient Data Analysis of Randomized Trials.

Authors: Kwak, Lucia, Ravi, Praful, Armstrong, John G., Beckendorf, Veronique, Chin, Joseph L., D'Amico, Anthony V., Dearnaley, David P., Di Stasi, Savino M., Gillessen, Silke, Lukka, Himanshu, Mottet, Nicolas, Pommier, Pascal, Seiferheld, Wendy, Sydes, Matthew R., Tombal, Bertrand, Zapatero, Almudena, Regan, Meredith M., Xie, Wanling, Sweeney, Christopher J.

Source: Journal of Clinical Oncology; 6/20/2024, Vol. 42 Issue 18, p2132-2138, 8p

Patient Reported Outcomes in NRG Oncology RTOG 0938, Evaluating Two Ultrahypofractionated Regimens for Prostate Cancer

Authors: Lukka, Himanshu R., Pugh, Stephanie L., Bruner, Deborah W., Bahary, Jean-Paul, Lawton, Colleen A.F., Efstathiou, Jason A., Kudchadker, Rajat J., Ponsky, Lee E., Seaward, Samantha A., Dayes, Ian S., Gopaul, Darindra D., Michalski, Jeff M., Delouya, Guila, Kaplan, Irving D., Horwitz, Eric M., Roach, Mack, Pinover, Wayne H., Beyer, David C., Amanie, John O., Sandler, Howard M., Kachnic, Lisa A.

Source: International journal of radiation oncology, biology, physics. 102(2):287-295

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100067283911.0x000001&indx=1&recIds=ETOCvdc_100067283911.0x000001

Disease control outcomes of stereotactic body radiation therapy or moderate hypo‐fractionation for prostate cancer: Real‐world experience at two Canadian centers.

Authors: Hu, Hsin‐pei, Anagnostopoulos, Gregory, Gouran‐Savadkoohi, Mohammad, Dayes, Ian, Ishkanian, Adrian, Hallock, Abhirami, Lukka, Himanshu, Quan, Kimmen, Schnarr, Kara, Cuthbert, David, Goldberg, Mira, Chang, Yi Meng, Tsakiridis, Theodoros

Source: Prostate; Feb2024, Vol. 84 Issue 2, p193-202, 10p

Impact of lymph node yield at prostatectomy on outcomes in NRG/RTOG 9601.

Authors: Chan, Emily, Pugh, Stephanie L., Simko, Jeff, Feng, Felix Y, Shipley, William U., Lukka, Himanshu, Bahary, Jean-Paul, Pisansky, Thomas Michael, Zeitzer, Kenneth Lee, Lawton, Colleen Anne, Efstathiou, Jason A., Rosenthal, Seth A., Balogh, Alexander G., Lovett, Richard Dana, Wong, Anthony C., Dess, Robert Timothy, McGinnis, Scott, Kuettel, Michael R., Demora, Lyudmila, Sandler, Howard M.

Source: Journal of clinical oncology. 40(6 suppl):265-265

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100152986399.0x000001&indx=1&recIds=ETOCvdc_100152986399.0x000001

1359: Individual patient data analysis of salvage radiotherapy trials: RTOG 0534 and GETUG-AFU 16

Authors: Mohamad, Osama, Pugh, Stephanie, Pommier, Pascal, Pollack, Alan, Lukka, Himanshu R., Rutledge, Robert, Martin, Andre- Guy, Patel, Shyamal, Sarin, David, Balogh, Alexander G., Michalski, Jeff M., Vavassis, Peter, Guerif, Stéphane, Supiot, Stephane, Latorzeff, Igor, Chabaud, Sylvie, Brihoum, Meryem, Lyness, Jessica, Sandler, Howard, Sargos, Paul, Feng, Felix Y.

Source: In Radiotherapy and Oncology May 2024 194 Supplement 1:S2426-S2427

206: A Randomized Phase Ii Trial of Prostate Boost Irradiation with Stereotactic Body Radiotherapy (SBRT) in High-Risk Prostate Cancer. The Pbs Trial

Authors: Douvi, Georgia, Isfahanian, Naghmeh, Lukka, Himanshu, Quan, Kimmen, Schnarr, Kara Lynne, Goldberg, Mira, Wright, Jim, Hallock, Abhirami, Ishkanian, Adrian, Cuthbert, David, Swaminath, Anand, Chow, Tom, Diamond, Kevin, Cutz, Jean-Claude, Kavsak, Peter, Thabane, Lehana, Tsakiridis, Theodoros

Source: Radiotherapy and oncology. 150(S1):S87-S88

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100110962804.0x000001&indx=1&recIds=ETOCvdc_100110962804.0x000001

147 Evaluation of Volumetric Response Assessment from Stereotactic Ablative Radiotherapy (SABR) for Renal Cell Carcinoma (RCC)

Authors: Schep, Daniel, Dayes, Ian, Lukka, Himanshu, Quan, Kimmen, Kapoor, Anil, Vansantvoort, Jasmin, Chow, Tom, Swaminath, Anand

Source: In Radiotherapy and Oncology September 2023 186 Supplement 1:S67-S67

151: Prostate SBRT Boost Radiotherapy (PBS Trial): A Randomized Phase II Trial of SBRT Versus Conventionally-Fractionated Radiotherapy Boost Following Pelvic Radiotherapy in High-Risk Prostate Cancer

Authors: Mesci, Aruz, Isfahanian, Naghmeh, Douvi, Georgia, Gouran-Savadkoohi, Mohammad, Dayes, Ian, Lukka, Himanshu, Quan, Kimmen, Schnarr, Kara, Goldberg, Mira, Hallock, Abhirami, Chow, Tom, Diamond, Kevin, Jakubovic, Raphael, Thabane, Lahane, Tsakiridis, Theodoros

Source: Radiotherapy and oncology. 163(S1):S64-S64

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100152308113.0x000001&indx=1&recIds=ETOCvdc_100152308113.0x000001

18: PSMA-PET-Based Response Assessment of Metastatic Prostate Cancer Response to Radiotherapy: A Case Series

Authors: Mesci, Aruz, Gouran-Savadkoohi, Mohammad, Greenspoon, Jeffrey, Kapoor, Anil, Lukka, Himanshu, Tsakiridis, Theodoros

Source: Radiotherapy and oncology. 163(S1):S11-S11

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100149450345.0x000001&indx=1&recIds=ETOCvdc_100149450345.0x000001

62: A Prospective Provincial Psma-Pet Registry for Recurrent Prostate Cancer: Preliminary Results

Authors: Liu, Wei, Bauman, Glenn, Zukotynski, Katherine, Finelli, Antonio, Chin, Joseph, Klotz, Laurence, Lukka, Himanshu, Lavallee, Luke, Hagerty, Marlon, Metser, Ur

Source: Radiotherapy and oncology. 150(S1):S30-S30

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100110963617.0x000001&indx=1&recIds=ETOCvdc_100110963617.0x000001