Design, Synthesis, Antitumor, and Antiplasmodial Evaluation of New 7-Chloroquinoline–Benzimidazole Hybrids

Authors: Luka Krstulović, Vesna Rastija, Lais Pessanha de Carvalho, Jana Held, Zrinka Rajić, Zorislava Živković, Miroslav Bajić, Ljubica Glavaš-Obrovac

Source: Molecules, Vol 29, Iss 13, p 2997 (2024)

Subject Terms: quinoline–benzimidazole hybrids, synthesis of benzimidazoles, nucleophilic substitution, oxidative coupling of cyclocondesation, antiproliferative effect, antiplasmodial effect, Organic chemistry, QD241-441

File Description: electronic resource

Relation: https://www.mdpi.com/1420-3049/29/13/2997; https://doaj.org/toc/1420-3049

Access URL: https://doaj.org/article/10989b5d69254f9ab784c39dddd36a84

Novel 1,2,3-Triazole-Containing Quinoline–Benzimidazole Hybrids: Synthesis, Antiproliferative Activity, In Silico ADME Predictions, and Docking

Authors: Luka Krstulović, Katarina Mišković Špoljarić, Vesna Rastija, Nikolina Filipović, Miroslav Bajić, Ljubica Glavaš-Obrovac

Source: Molecules, Vol 28, Iss 19, p 6950 (2023)

Subject Terms: 1,2,3-triazole-containing quinoline–benzimidazole hybrids, synthesis, antiproliferative effect, in silico ADME, docking, Organic chemistry, QD241-441

File Description: electronic resource

Relation: https://www.mdpi.com/1420-3049/28/19/6950; https://doaj.org/toc/1420-3049

Access URL: https://doaj.org/article/f6990192a90b4527ae1cb55b7e5bc47a

Novel 7-Chloro-4-aminoquinoline-benzimidazole Hybrids as Inhibitors of Cancer Cells Growth: Synthesis, Antiproliferative Activity, in Silico ADME Predictions, and Docking

Authors: Luka Krstulović, Marijana Leventić, Vesna Rastija, Kristina Starčević, Maja Jirouš, Ivana Janić, Maja Karnaš, Kornelija Lasić, Miroslav Bajić, Ljubica Glavaš-Obrovac

Source: Molecules, Vol 28, Iss 2, p 540 (2023)

Subject Terms: aminoquinoline-benzimidazole hybrids, anticancer, in silico ADME, docking, cell cycle perturbation, mitochondrial membrane potential, Organic chemistry, QD241-441

File Description: electronic resource

Relation: https://www.mdpi.com/1420-3049/28/2/540; https://doaj.org/toc/1420-3049

Access URL: https://doaj.org/article/7e6b3d11d863498390bdf29269f98c24

An aromatic imidazoline derived from chloroquinoline triggers cell cycle arrest and inhibits with high selectivity the Trypanosoma cruzi mammalian host-cells infection.

Authors: Roberto I Cuevas-Hernández, Richard M B M Girard, Luka Krstulović, Miroslav Bajić, Ariel Mariano Silber

Source: PLoS Neglected Tropical Diseases, Vol 15, Iss 11, p e0009994 (2021)

Subject Terms: Arctic medicine. Tropical medicine, RC955-962, Public aspects of medicine, RA1-1270

File Description: electronic resource

Relation: https://doaj.org/toc/1935-2727; https://doaj.org/toc/1935-2735

Access URL: https://doaj.org/article/0589b3b616b249a98abd20745078f37d

Synthesis, anti-bacterial and anti-protozoal activities of amidinobenzimidazole derivatives and their interactions with DNA and RNA

Authors: Andrea Bistrović, Luka Krstulović, Ivana Stolić, Domagoj Drenjančević, Jasminka Talapko, Martin C. Taylor, John M. Kelly, Miroslav Bajić, Silvana Raić-Malić

Source: Journal of Enzyme Inhibition and Medicinal Chemistry, Vol 33, Iss 1, Pp 1323-1334 (2018)

Subject Terms: Benzimidazole, 1,2,3-triazole, resistant bacteria, antiprotozoal activity, Trypanosoma brucei, MRSA, Therapeutics. Pharmacology, RM1-950

File Description: electronic resource

Relation: https://doaj.org/toc/1475-6366; https://doaj.org/toc/1475-6374

Access URL: https://doaj.org/article/e0697d37ff024c3b90f523c1633faed8