Hypothalamic hormone deficiency enables physiological anorexia in ground squirrels during hibernation

Authors: Sarah M. Mohr, Rafael Dai Pra, Maryann P. Platt, Viktor V. Feketa, Marya Shanabrough, Luis Varela, Ashley Kristant, Haoran Cao, Dana K. Merriman, Tamas L. Horvath, Sviatoslav N. Bagriantsev, Elena O. Gracheva

Source: Nature Communications, Vol 15, Iss 1, Pp 1-15 (2024)

Subject Terms: Science

File Description: electronic resource

Relation: https://doaj.org/toc/2041-1723

Access URL: https://doaj.org/article/85482d9133b24981b7be3db42e371392

Folliculogenesis: A Cellular Crosstalk Mechanism

Authors: Bianca Viviana Orozco-Galindo, Blanca Sánchez-Ramírez, Cynthia Lizeth González-Trevizo, Beatriz Castro-Valenzuela, Luis Varela-Rodríguez, M. Eduviges Burrola-Barraza

Source: Current Issues in Molecular Biology, Vol 47, Iss 2, p 113 (2025)

Subject Terms: folliculogenesis, crosstalk, oocyte, follicle, embryo, Biology (General), QH301-705.5

File Description: electronic resource

Relation: https://www.mdpi.com/1467-3045/47/2/113; https://doaj.org/toc/1467-3037; https://doaj.org/toc/1467-3045

Access URL: https://doaj.org/article/ea651bfdd4c341fcb14107ea0baa8567

microRNA-33 controls hunger signaling in hypothalamic AgRP neurons

Authors: Nathan L. Price, Pablo Fernández-Tussy, Luis Varela, Magdalena P. Cardelo, Marya Shanabrough, Binod Aryal, Rafael de Cabo, Yajaira Suárez, Tamas L. Horvath, Carlos Fernández-Hernando

Source: Nature Communications, Vol 15, Iss 1, Pp 1-13 (2024)

Subject Terms: Science

File Description: electronic resource

Relation: https://doaj.org/toc/2041-1723

Access URL: https://doaj.org/article/f1a854edd40041bf8676f1f698ab6e77

CerS6-dependent ceramide synthesis in hypothalamic neurons promotes ER/mitochondrial stress and impairs glucose homeostasis in obese mice

Authors: Philipp Hammerschmidt, Sophie M. Steculorum, Cécile L. Bandet, Almudena Del Río-Martín, Lukas Steuernagel, Vivien Kohlhaas, Marvin Feldmann, Luis Varela, Adam Majcher, Marta Quatorze Correia, Rhena F. U. Klar, Corinna A. Bauder, Ecem Kaya, Marta Porniece, Nasim Biglari, Anna Sieben, Tamas L. Horvath, Thorsten Hornemann, Susanne Brodesser, Jens C. Brüning

Source: Nature Communications, Vol 14, Iss 1, Pp 1-22 (2023)

Subject Terms: Science

File Description: electronic resource

Relation: https://doaj.org/toc/2041-1723

Access URL: https://doaj.org/article/0ef32131373a4665897de31f813f7c3c

Validación de la versión reducida de la escala de depresión geriátrica en el consultorio externo de geriatría del Hospital Nacional Cayetano Heredia

Authors: Jeanie De la torre Maslucan, Rosa Shimabukuro Maeki, Luis Varela Pinedo, Hever Hever Krüger Malpartida, Leandro Huayanay Falconí, Javier Cieza Zevallos, Miguel Gálvez Cano

Source: Acta Médica Peruana, Vol 23, Iss 3 (2024)

Subject Terms: Depresión, Adultos mayores, GDS, Medicine

File Description: electronic resource

Relation: https://amp.cmp.org.pe/index.php/AMP/article/view/1179; https://doaj.org/toc/1018-8800; https://doaj.org/toc/1728-5917

Access URL: https://doaj.org/article/b60d3aa07d974dc5b6a68867ea39b0b8

Healthcare resource utilization and costs among patients with heart failure with preserved, mildly reduced, and reduced ejection fraction in Spain

Authors: Carlos Escobar, Beatriz Palacios, Luis Varela, Martín Gutiérrez, Mai Duong, Hungta Chen, Nahila Justo, Javier Cid-Ruzafa, Ignacio Hernández, Phillip R. Hunt, Juan F. Delgado

Source: BMC Health Services Research, Vol 22, Iss 1, Pp 1-16 (2022)

Subject Terms: Cost, Heart failure, Healthcare resource utilization, Hospitalization, Sacubitril/valsartan, SGLT2 inhibitors, Public aspects of medicine, RA1-1270

File Description: electronic resource

Relation: https://doaj.org/toc/1472-6963

Access URL: https://doaj.org/article/1e346887883241cca4bd4817e2403de7

Cerebellar Kv3.3 potassium channels activate TANK-binding kinase 1 to regulate trafficking of the cell survival protein Hax-1

Authors: Yalan Zhang, Luis Varela, Klara Szigeti-Buck, Adam Williams, Milan Stoiljkovic, Matija Šestan-Peša, Jorge Henao-Mejia, Pasquale D’Acunzo, Efrat Levy, Richard A. Flavell, Tamas L. Horvath, Leonard K. Kaczmarek

Source: Nature Communications, Vol 12, Iss 1, Pp 1-17 (2021)

Subject Terms: Science

File Description: electronic resource

Relation: https://doaj.org/toc/2041-1723

Access URL: https://doaj.org/article/13d7eef65e4645d8b409edf85235aea3

Costs and healthcare utilisation of patients with heart failure in Spain

Authors: Carlos Escobar, Luis Varela, Beatriz Palacios, Margarita Capel, Antoni Sicras, Aram Sicras, Antonio Hormigo, Roberto Alcázar, Nicolás Manito, Manuel Botana

Source: BMC Health Services Research, Vol 20, Iss 1, Pp 1-11 (2020)

Subject Terms: Heart failure cost, Dapagliflozin, DAPA-HF, Heart failure, Hospitalization, Sacubitril/valsartan, Public aspects of medicine, RA1-1270

File Description: electronic resource

Relation: http://link.springer.com/article/10.1186/s12913-020-05828-9; https://doaj.org/toc/1472-6963

Access URL: https://doaj.org/article/44057c7e20004cb2809050bb5c90f430

Effect of Gallic acid and Myricetin on ovarian cancer models: a possible alternative antitumoral treatment

Authors: Luis Varela-Rodríguez, Blanca Sánchez-Ramírez, Verónica Ivonne Hernández-Ramírez, Hugo Varela-Rodríguez, Rodrigo Daniel Castellanos-Mijangos, Carmen González-Horta, Bibiana Chávez-Munguía, Patricia Talamás-Rohana

Source: BMC Complementary Medicine and Therapies, Vol 20, Iss 1, Pp 1-16 (2020)

Subject Terms: Antineoplastic activity, Nu/Nu mice, OVCAR-3, Peritumoral route, SKOV-3, Toxicity, Other systems of medicine, RZ201-999

File Description: electronic resource

Relation: http://link.springer.com/article/10.1186/s12906-020-02900-z; https://doaj.org/toc/2662-7671

Access URL: https://doaj.org/article/745a555c84eb4a168742b7ecbbd9aef8

Primary vs. Secondary Heart Failure Diagnosis: Differences in Clinical Outcomes, Healthcare Resource Utilization and Cost

Authors: Héctor Bueno, Clara Goñi, Rafael Salguero-Bodes, Beatriz Palacios, Lourdes Vicent, Guillermo Moreno, Nicolás Rosillo, Luis Varela, Margarita Capel, Juan Delgado, Fernando Arribas, Manuel del Oro, Carmen Ortega, Jose L. Bernal

Source: Frontiers in Cardiovascular Medicine, Vol 9 (2022)

Subject Terms: heart failiure, secondary diagnosis, outcome, mortality, resource utilization, cost, Diseases of the circulatory (Cardiovascular) system, RC666-701

File Description: electronic resource

Relation: https://www.frontiersin.org/articles/10.3389/fcvm.2022.818525/full; https://doaj.org/toc/2297-055X

Access URL: https://doaj.org/article/4ae4c1b73738464293801569747b5fa9

Quality of life and disease experience in patients with heart failure with reduced ejection fraction in Spain: a mixed-methods study

Authors: Cristina Enjuanes, Josep Comin-Colet, Pedro Moliner, Raül Rubio, Beatriz Palacios, Luis Varela, Raquel Fernández, Selene Camargo Correa, María Fernanda Estupiñan, Elena Calvo, Nuria José, Marta Ruiz Muñoz, Sergi Yun, Santiago Jiménez-Marrero, Lidia Alcoberro, Alberto Garay, Lydia Sánchez-Fernández, María Teresa Soria Gómez, Encarna Hidalgo, Esther Calero-Molina, Yolanda Rueda, Maite San Saturnino, Paloma Garcimartín, Jorge V López-Ibor, Javier Segovia-Cubero

Source: BMJ Open, Vol 11, Iss 12 (2021)

Subject Terms: Medicine

File Description: electronic resource

Relation: https://bmjopen.bmj.com/content/11/12/e053216.full; https://doaj.org/toc/2044-6055

Access URL: https://doaj.org/article/b67bdc7772694fe3a3244dcdd7d15f49

Biological and toxicological evaluation of Rhus trilobata Nutt. (Anacardiaceae) used traditionally in mexico against cancer

Authors: Luis Varela-Rodríguez, Blanca Sánchez-Ramírez, Ivette Stephanie Rodríguez-Reyna, José Juan Ordaz-Ortiz, David Chávez-Flores, Erika Salas-Muñoz, Juan Carlos Osorio-Trujillo, Ernesto Ramos-Martínez, Patricia Talamás-Rohana

Source: BMC Complementary and Alternative Medicine, Vol 19, Iss 1, Pp 1-18 (2019)

Subject Terms: Acute toxicity, Biological activity, β-PGG, Colorectal adenocarcinoma, Phytochemical composition, Rhus trilobata, Other systems of medicine, RZ201-999

File Description: electronic resource

Relation: http://link.springer.com/article/10.1186/s12906-019-2566-9; https://doaj.org/toc/1472-6882

Access URL: https://doaj.org/article/a550e54873924d5db629bfd23d102547

Functional Characterization of the Lin28/let-7 Circuit During Forelimb Regeneration in Ambystoma mexicanum and Its Influence on Metabolic Reprogramming

Authors: Hugo Varela-Rodríguez, Diana G. Abella-Quintana, Annie Espinal-Centeno, Luis Varela-Rodríguez, David Gomez-Zepeda, Juan Caballero-Pérez, Paola L. García-Medel, Luis G. Brieba, José J. Ordaz-Ortiz, Alfredo Cruz-Ramirez

Source: Frontiers in Cell and Developmental Biology, Vol 8 (2020)

Subject Terms: Lin28, let-7, epimorphic regeneration, axolotl (Ambystoma mexicanum), metabolic reprogramming, Biology (General), QH301-705.5

File Description: electronic resource

Relation: https://www.frontiersin.org/articles/10.3389/fcell.2020.562940/full; https://doaj.org/toc/2296-634X

Access URL: https://doaj.org/article/cf9b38cf898e4836ab2caea4a387f79b

Brown adipose tissue derived ANGPTL4 controls glucose and lipid metabolism and regulates thermogenesis

Authors: Abhishek K. Singh, Binod Aryal, Balkrishna Chaube, Noemi Rotllan, Luis Varela, Tamas L. Horvath, Yajaira Suárez, Carlos Fernández-Hernando

Source: Molecular Metabolism, Vol 11, Iss , Pp 59-69 (2018)

Subject Terms: Internal medicine, RC31-1245

File Description: electronic resource

Relation: http://www.sciencedirect.com/science/article/pii/S2212877818302278; https://doaj.org/toc/2212-8778

Access URL: https://doaj.org/article/5e28d6f791074ddbaf00aad1320938a9

Efektivitas Pembelajaran Berbasis Masalah terhadap Pemahaman Konsep Usaha dan Energi

Authors: Luis Varela, Lia Yuliati, Arif Hidayat

Source: Jurnal Pendidikan: Teori, Penelitian, dan Pengembangan, Vol 4, Iss 5 (2019)

Subject Terms: problem-based learning, conceptual understanding, work and energy, pembelajaran berbasis masalah, pemahaman konsep, usaha dan energi, Education, Education (General), L7-991

File Description: electronic resource

Relation: http://journal.um.ac.id/index.php/jptpp/article/view/12420; https://doaj.org/toc/2502-471X

Access URL: https://doaj.org/article/ca470184b2154abebe51b1ee46c16e00

Antineoplastic Activity of Rhus trilobata Nutt. (Anacardiaceae) against Ovarian Cancer and Identification of Active Metabolites in This Pathology

Authors: Luis Varela-Rodríguez, Blanca Sánchez-Ramírez, Erika Saenz-Pardo-Reyes, José Juan Ordaz-Ortiz, Rodrigo Daniel Castellanos-Mijangos, Verónica Ivonne Hernández-Ramírez, Carlos Martín Cerda-García-Rojas, Carmen González-Horta, Patricia Talamás-Rohana

Source: Plants, Vol 10, Iss 10, p 2074 (2021)

Subject Terms: antineoplastic activity, gallic acid, myricetin, ovarian cancer, Rhus trilobata, Botany, QK1-989

File Description: electronic resource

Relation: https://www.mdpi.com/2223-7747/10/10/2074; https://doaj.org/toc/2223-7747

Access URL: https://doaj.org/article/be0f21203d534ea7a1a3f0b75030abae

Zika Virus Disrupts Phospho-TBK1 Localization and Mitosis in Human Neuroepithelial Stem Cells and Radial Glia

Authors: Marco Onorati, Zhen Li, Fuchen Liu, André M.M. Sousa, Naoki Nakagawa, Mingfeng Li, Maria Teresa Dell’Anno, Forrest O. Gulden, Sirisha Pochareddy, Andrew T.N. Tebbenkamp, Wenqi Han, Mihovil Pletikos, Tianliuyun Gao, Ying Zhu, Candace Bichsel, Luis Varela, Klara Szigeti-Buck, Steven Lisgo, Yalan Zhang, Anze Testen, Xiao-Bing Gao, Jernej Mlakar, Mara Popovic, Marie Flamand, Stephen M. Strittmatter, Leonard K. Kaczmarek, E.S. Anton, Tamas L. Horvath, Brett D. Lindenbach, Nenad Sestan

Source: Cell Reports, Vol 16, Iss 10, Pp 2576-2592 (2016)

Subject Terms: Biology (General), QH301-705.5

File Description: electronic resource

Relation: http://www.sciencedirect.com/science/article/pii/S2211124716311020; https://doaj.org/toc/2211-1247

Access URL: https://doaj.org/article/7ed0523b8c024cdea2dcfa2c3cd7c835

Role of mitochondrial uncoupling protein-2 (UCP2) in higher brain functions, neuronal plasticity and network oscillation

Authors: Gretchen Hermes, David Nagy, Michael Waterson, Attila Zsarnovszky, Luis Varela, Mihaly Hajos, Tamas L. Horvath

Source: Molecular Metabolism, Vol 5, Iss 6, Pp 415-421 (2016)

Subject Terms: Internal medicine, RC31-1245

File Description: electronic resource

Relation: http://www.sciencedirect.com/science/article/pii/S2212877816300060; https://doaj.org/toc/2212-8778

Access URL: https://doaj.org/article/3c0ece7bb1f2490cbaa9a7be0187926a

Mitochondria controlled by UCP2 determine hypoxia-induced synaptic remodeling in the cortex and hippocampus

Authors: Luis Varela, Michael L. Schwartz, Tamas L. Horvath

Source: Neurobiology of Disease, Vol 90, Iss , Pp 68-74 (2016)

Subject Terms: Perinatal hypoxia, Mitochondria, UCP2, Synaptic plasticity, Cortex, Hippocampus, Neurosciences. Biological psychiatry. Neuropsychiatry, RC321-571

File Description: electronic resource

Relation: http://www.sciencedirect.com/science/article/pii/S0969996116300031; https://doaj.org/toc/1095-953X

Access URL: https://doaj.org/article/5ad6f09d7a474cb289fb8d97e8f2e538

Frailty in older adults: detection, community-based intervention, and decision-making in the management of chronic illnessesFrailty in older adults: detection, community-based intervention, and decision-making in the management of chronic illnesses

Authors: Tania Tello-Rodríguez, Luis Varela-Pinedo

Source: Revista Peruana de Medicina Experimental y Salud Pública, Vol 33, Iss 2, Pp 328-334 (2016)

Subject Terms: anciano frágil, anciano, intervención médica temprana, enfermedad crónica, Medicine, Medicine (General), R5-920

File Description: electronic resource

Relation: https://rpmesp.ins.gob.pe/index.php/rpmesp/article/view/2207; https://doaj.org/toc/1726-4634; https://doaj.org/toc/1726-4642

Access URL: https://doaj.org/article/ead4ce121c734deb8bb79955ab966e3b