Single-cell AI-based detection and prognostic and predictive value of DNA mismatch repair deficiency in colorectal cancer

Authors: Marta Nowak, Faiz Jabbar, Ann-Katrin Rodewald, Luciana Gneo, Tijana Tomasevic, Andrea Harkin, Tim Iveson, Mark Saunders, Rachel Kerr, Karin Oein, Noori Maka, Jennifer Hay, Joanne Edwards, Ian Tomlinson, Owen Sansom, Caroline Kelly, Francesco Pezzella, David Kerr, Alistair Easton, Enric Domingo, Viktor H. Koelzer, David N. Church, Bengt Glimelius, Ismail Gogenur, Emma Jaeger, Hannah Morgan, Clare Orange, Claire Palles, Campbell Roxburgh

Source: Cell Reports Medicine, Vol 5, Iss 9, Pp 101727- (2024)

Subject Terms: colorectal cancer, mismatch repair deficiency, microsatellite instability, AI, digital pathology, Medicine (General), R5-920

File Description: electronic resource

Relation: http://www.sciencedirect.com/science/article/pii/S2666379124004543; https://doaj.org/toc/2666-3791

Access URL: https://doaj.org/article/0addef455aaa46a896ad776bd6ad5c75

Accounting for intensity variation in image analysis of large‐scale multiplexed clinical trial datasets

Authors: Anja L Frei, Anthony McGuigan, Ritik RAK Sinha, Mark A Glaire, Faiz Jabbar, Luciana Gneo, Tijana Tomasevic, Andrea Harkin, Tim J Iveson, Mark Saunders, Karin Oein, Noori Maka, Francesco Pezella, Leticia Campo, Jennifer Hay, Joanne Edwards, Owen J Sansom, Caroline Kelly, Ian Tomlinson, Wanja Kildal, Rachel S Kerr, David J Kerr, Håvard E Danielsen, Enric Domingo, TransSCOT Consortium, David N Church, Viktor H Koelzer

Source: The Journal of Pathology: Clinical Research, Vol 9, Iss 6, Pp 449-463 (2023)

Subject Terms: digital pathology, fluorescence microscopy, image analysis, Pathology, RB1-214

File Description: electronic resource

Relation: https://doaj.org/toc/2056-4538

Access URL: https://doaj.org/article/d2fd350d290249e6b38f3b09f966ff54

Targeting Amino Acid Metabolic Vulnerabilities in Myeloid Malignancies

Authors: Livingstone Fultang, Luciana Gneo, Carmela De Santo, Francis J. Mussai

Source: Frontiers in Oncology, Vol 11 (2021)

Subject Terms: amino acids, metabolism, therapy, myeloid dysplasia, myeloid neoplasia, Neoplasms. Tumors. Oncology. Including cancer and carcinogens, RC254-282

File Description: electronic resource

Relation: https://www.frontiersin.org/articles/10.3389/fonc.2021.674720/full; https://doaj.org/toc/2234-943X

Access URL: https://doaj.org/article/df47f1418fea4ca09c19f3485f2950f0

The oncogenic neurotrophin receptor tropomyosin-related kinase variant, TrkAIII

Authors: Antonietta Rosella Farina, Lucia Cappabianca, Pierdomenico Ruggeri, Luciana Gneo, Cristina Pellegrini, Maria-Concetta Fargnoli, Andrew Reay Mackay

Source: Journal of Experimental & Clinical Cancer Research, Vol 37, Iss 1, Pp 1-17 (2018)

Subject Terms: TrkAIII, Alternative splicing, Neuroblastoma, Oncogenic signaling, Unfolded protein response, Warburg effect, Neoplasms. Tumors. Oncology. Including cancer and carcinogens, RC254-282

File Description: electronic resource

Relation: http://link.springer.com/article/10.1186/s13046-018-0786-3; https://doaj.org/toc/1756-9966

Access URL: https://doaj.org/article/2b4013d27daf4d3f8f98e0f418c8d8ac