Structuring lipid nanoparticles, DNA, and protein corona into stealth bionanoarchitectures for in vivo gene delivery

Authors: Serena Renzi, Luca Digiacomo, Daniela Pozzi, Erica Quagliarini, Elisabetta Vulpis, Maria Valeria Giuli, Angelica Mancusi, Bianca Natiello, Maria Gemma Pignataro, Gianluca Canettieri, Laura Di Magno, Luca Pesce, Valentina De Lorenzi, Samuele Ghignoli, Luisa Loconte, Carmela Maria Montone, Anna Laura Capriotti, Aldo Laganà, Carmine Nicoletti, Heinz Amenitsch, Marco Rossi, Francesco Mura, Giacomo Parisi, Francesco Cardarelli, Alessandra Zingoni, Saula Checquolo, Giulio Caracciolo

Source: Nature Communications, Vol 15, Iss 1, Pp 1-20 (2024)

Subject Terms: Science

File Description: electronic resource

Relation: https://doaj.org/toc/2041-1723

Access URL: https://doaj.org/article/0ac4519bb8ec417189f0144fcc73185a

Enhancing Immune Responses against SARS-CoV‑2 Variants in Aged Mice with INDUK: A Chimeric DNA Vaccine Encoding the Spike S1-TM Subunits

Authors: Lishan Cui, Junbiao Wang, Fiorenza Orlando, Robertina Giacconi, Marco Malavolta, Beatrice Bartozzi, Roberta Galeazzi, Giorgia Giorgini, Luca Pesce, Francesco Cardarelli, Erica Quagliarini, Serena Renzi, Siyao Xiao, Daniela Pozzi, Mauro Provinciali, Giulio Caracciolo, Cristina Marchini, Augusto Amici

Source: ACS Omega, Vol 9, Iss 32, Pp 34624-34635 (2024)

Subject Terms: Chemistry, QD1-999

File Description: electronic resource

Relation: https://doaj.org/toc/2470-1343

Access URL: https://doaj.org/article/0060469d652c4b548de5d8976672ba5b

Unveiling nanoscale optical signatures of cytokine-induced β-cell dysfunction

Authors: Licia Anna Pugliese, Valentina De Lorenzi, Mario Bernardi, Samuele Ghignoli, Marta Tesi, Piero Marchetti, Luca Pesce, Francesco Cardarelli

Source: Scientific Reports, Vol 13, Iss 1, Pp 1-14 (2023)

Subject Terms: Medicine, Science

File Description: electronic resource

Relation: https://doaj.org/toc/2045-2322

Access URL: https://doaj.org/article/9e18d4bea59d4241ad74de59994a2c61

Pioglitazone Phases and Metabolic Effects in Nanoparticle-Treated Cells Analyzed via Rapid Visualization of FLIM Images

Authors: Biagio Todaro, Luca Pesce, Francesco Cardarelli, Stefano Luin

Source: Molecules, Vol 29, Iss 9, p 2137 (2024)

Subject Terms: fluorescence lifetime imaging microscopy (FLIM), pioglitazone characterization, insulinoma (INS-1) cells, PLGA nanoparticles, phasor-FLIM analysis, MATLAB tool, Organic chemistry, QD241-441

File Description: electronic resource

Relation: https://www.mdpi.com/1420-3049/29/9/2137; https://doaj.org/toc/1420-3049

Access URL: https://doaj.org/article/c725cb77cfc7422d94d5476cae1cf0a8

Single-cell imaging of α and β cell metabolic response to glucose in living human Langerhans islets

Authors: Fabio Azzarello, Luca Pesce, Valentina De Lorenzi, Gianmarco Ferri, Marta Tesi, Silvia Del Guerra, Piero Marchetti, Francesco Cardarelli

Source: Communications Biology, Vol 5, Iss 1, Pp 1-10 (2022)

Subject Terms: Biology (General), QH301-705.5

File Description: electronic resource

Relation: https://doaj.org/toc/2399-3642

Access URL: https://doaj.org/article/fee9754a33d1426aa502b61850e53623

3D molecular phenotyping of cleared human brain tissues with light-sheet fluorescence microscopy

Authors: Luca Pesce, Marina Scardigli, Vladislav Gavryusev, Annunziatina Laurino, Giacomo Mazzamuto, Niamh Brady, Giuseppe Sancataldo, Ludovico Silvestri, Christophe Destrieux, Patrick R. Hof, Irene Costantini, Francesco S. Pavone

Source: Communications Biology, Vol 5, Iss 1, Pp 1-12 (2022)

Subject Terms: Biology (General), QH301-705.5

File Description: electronic resource

Relation: https://doaj.org/toc/2399-3642

Access URL: https://doaj.org/article/e482466fc9d14136bc40195885614206

Living supramolecular polymerization of fluorinated cyclohexanes

Authors: Oleksandr Shyshov, Shyamkumar Vadakket Haridas, Luca Pesce, Haoyuan Qi, Andrea Gardin, Davide Bochicchio, Ute Kaiser, Giovanni M. Pavan, Max von Delius

Source: Nature Communications, Vol 12, Iss 1, Pp 1-11 (2021)

Subject Terms: Science

File Description: electronic resource

Relation: https://doaj.org/toc/2041-1723

Access URL: https://doaj.org/article/8f8bf435b7ae4e9b825de4653c821621

Swarm-CG: Automatic Parametrization of Bonded Terms in MARTINI-Based Coarse-Grained Models of Simple to Complex Molecules via Fuzzy Self-Tuning Particle Swarm Optimization

Authors: Charly Empereur-Mot, Luca Pesce, Giovanni Doni, Davide Bochicchio, Riccardo Capelli, Claudio Perego, Giovanni M. Pavan

Source: ACS Omega, Vol 5, Iss 50, Pp 32823-32843 (2020)

Subject Terms: Chemistry, QD1-999

File Description: electronic resource

Relation: https://doaj.org/toc/2470-1343

Access URL: https://doaj.org/article/67cce85f6c684f7d8e6283be25eb351b

Comparison of Different Tissue Clearing Methods for Three-Dimensional Reconstruction of Human Brain Cellular Anatomy Using Advanced Imaging Techniques

Authors: Marina Scardigli, Luca Pesce, Niamh Brady, Giacomo Mazzamuto, Vladislav Gavryusev, Ludovico Silvestri, Patrick R. Hof, Christophe Destrieux, Irene Costantini, Francesco S. Pavone

Source: Frontiers in Neuroanatomy, Vol 15 (2021)

Subject Terms: clearing techniques, optical microscopy, immunofluorescence, light-sheet fluorescence microscopy, expansion microscopy, Neurosciences. Biological psychiatry. Neuropsychiatry, RC321-571, Human anatomy, QM1-695

File Description: electronic resource

Relation: https://www.frontiersin.org/articles/10.3389/fnana.2021.752234/full; https://doaj.org/toc/1662-5129

Access URL: https://doaj.org/article/7792613291ca417ab4f5bdea08653169

Exploiting the tunability of stimulated emission depletion microscopy for super-resolution imaging of nuclear structures

Authors: Maria J. Sarmento, Michele Oneto, Simone Pelicci, Luca Pesce, Lorenzo Scipioni, Mario Faretta, Laura Furia, Gaetano Ivan Dellino, Pier Giuseppe Pelicci, Paolo Bianchini, Alberto Diaspro, Luca Lanzanò

Source: Nature Communications, Vol 9, Iss 1, Pp 1-11 (2018)

Subject Terms: Science

File Description: electronic resource

Relation: https://doaj.org/toc/2041-1723

Access URL: https://doaj.org/article/c9c25d83d741467483f9fddb84e0dc3d

Spatiotemporal Correlation Spectroscopy Reveals a Protective Effect of Peptide-Based GLP-1 Receptor Agonism against Lipotoxicity on Insulin Granule Dynamics in Primary Human β-Cells

Authors: Gianmarco Ferri, Marta Tesi, Luca Pesce, Marco Bugliani, Francesca Grano, Margherita Occhipinti, Mara Suleiman, Carmela De Luca, Lorella Marselli, Piero Marchetti, Francesco Cardarelli

Source: Pharmaceutics, Vol 13, Iss 9, p 1403 (2021)

Subject Terms: pancreatic islets, β-cells, GLP-1 receptor agonism, syncollin, iMSD, insulin secretory granule dynamics, Pharmacy and materia medica, RS1-441

File Description: electronic resource

Relation: https://www.mdpi.com/1999-4923/13/9/1403; https://doaj.org/toc/1999-4923

Access URL: https://doaj.org/article/aa0914bbca114a1fa08a417e080d1084

Optical Clearing and Labeling for Light-sheet Fluorescence Microscopy in Large-scale Human Brain Imaging

Authors: Danila Di Meo, author¹, Josephine Ramazzotti, author¹, Marina Scardigli, author^{1, 2}, Franco Cheli, author¹, Luca Pesce, author^{1, 3}, Niamh Brady, author¹, Giacomo Mazzamuto, author^{1, 4, 5}, Irene Costantini, author^{1, 4, 6}, Francesco S. Pavone, author^{1, 4, 5}

Source: Journal of Visualized Experiments. (203)

Availability: http://www.jove.com/video/65960

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Scanning Electrochemical Microscopy: Using the Potentiometric Mode of SECM To Study the Mixed Potential Arising from Two Independent Redox Processes.

Authors: Serrapede, Mara¹, Denuault, Guy¹, gd@soton.ac.uk, Sosna, Maciej², Luca Pesce, Giovanni³, Ball, Richard J.³

Source: Analytical Chemistry; 9/3/2013, Vol. 85 Issue 17, p8341-8346, 6p