DNA methylation status classifies pleural mesothelioma cells according to their immune profile: implication for precision epigenetic therapy

Authors: Maria Fortunata Lofiego, Rossella Tufano, Emma Bello, Laura Solmonese, Francesco Marzani, Francesca Piazzini, Fabrizio Celesti, Francesca Pia Caruso, Teresa Maria Rosaria Noviello, Roberta Mortarini, Andrea Anichini, Michele Ceccarelli, Luana Calabrò, Michele Maio, Sandra Coral, Anna Maria Di Giacomo, Alessia Covre, on behalf of the EPigenetic Immune-oncology Consortium Airc (EPICA) investigators

Source: Journal of Experimental & Clinical Cancer Research, Vol 44, Iss 1, Pp 1-21 (2025)

Subject Terms: Pleural mesothelioma, DNA methylation, Epigenetic, Immunotherapy, Guadecitabine, Neoplasms. Tumors. Oncology. Including cancer and carcinogens, RC254-282

File Description: electronic resource

Relation: https://doaj.org/toc/1756-9966

Access URL: https://doaj.org/article/4d600bc863644107907857b863883cdb

Immunotherapy of mesothelioma: the evolving change of a long-standing therapeutic dream

Authors: Luana Calabrò, Giuseppe Bronte, Federica Grosso, Luigi Cerbone, Angelo Delmonte, Fabio Nicolini, Massimiliano Mazza, Anna Maria Di Giacomo, Alessia Covre, Maria Fortunata Lofiego, Lucio Crinò, Michele Maio

Source: Frontiers in Immunology, Vol 14 (2024)

Subject Terms: pleural mesothelioma, immunotherapy, immune checkpoint inhibitors, adoptive cell therapy, epigenetic drugs, Immunologic diseases. Allergy, RC581-607

File Description: electronic resource

Relation: https://www.frontiersin.org/articles/10.3389/fimmu.2023.1333661/full; https://doaj.org/toc/1664-3224

Access URL: https://doaj.org/article/8927fd98d7b248cbac772e012b06e713

The great need to overcome osimertinib resistance in advanced non-small cell lung cancer: from combination strategies to fourth-generation tyrosine kinase inhibitors

Authors: Giuseppe Bronte, Alessia Belloni, Luana Calabrò, Lucio Crinò

Source: Frontiers in Oncology, Vol 13 (2024)

Subject Terms: non-small cell lung cancer, osimertinib, resistance, tyrosine kinase inhibitor, allosteric inhibitor, Neoplasms. Tumors. Oncology. Including cancer and carcinogens, RC254-282

File Description: electronic resource

Relation: https://www.frontiersin.org/articles/10.3389/fonc.2023.1308460/full; https://doaj.org/toc/2234-943X

Access URL: https://doaj.org/article/2d089392ca0e43ac9eda67cf4918da8e

The emerging role of cancer nanotechnology in the panorama of sarcoma

Authors: Laura Mercatali, Silvia Vanni, Giacomo Miserocchi, Chiara Liverani, Chiara Spadazzi, Claudia Cocchi, Chiara Calabrese, Lorena Gurrieri, Valentina Fausti, Nada Riva, Damiano Genovese, Enrico Lucarelli, Maria Letizia Focarete, Toni Ibrahim, Luana Calabrò, Alessandro De Vita

Source: Frontiers in Bioengineering and Biotechnology, Vol 10 (2022)

Subject Terms: sarcoma, nanotechnology, lipid-based nanocarriers, polymeric nanoparticles, smart materials, Biotechnology, TP248.13-248.65

File Description: electronic resource

Relation: https://www.frontiersin.org/articles/10.3389/fbioe.2022.953555/full; https://doaj.org/toc/2296-4185

Access URL: https://doaj.org/article/f885ba5b521043b3ab3517835c5c98b4

A vision of immuno-oncology: the Siena think tank of the Italian network for tumor biotherapy (NIBIT) foundation

Authors: Michele Maio, Michael Lahn, Anna Maria Di Giacomo, Alessia Covre, Luana Calabrò, Ramy Ibrahim, Bernard Fox, The Siena Think Tank

Source: Journal of Experimental & Clinical Cancer Research, Vol 40, Iss 1, Pp 1-12 (2021)

Subject Terms: Immunotherapy, Novel treatments, PD1, PD-L1, Melanoma, Mesothelioma, Neoplasms. Tumors. Oncology. Including cancer and carcinogens, RC254-282

File Description: electronic resource

Relation: https://doaj.org/toc/1756-9966

Access URL: https://doaj.org/article/a9b82c832f1c477f829ff00e1f9882ca

Permanent diabetes insipidus in a patient with mesothelioma treated with immunotherapy

Authors: Lucia Brilli, Luana Calabrò, Michele Campanile, Tania Pilli, Cristina Agostinis, Alfonso Cerase, Michele Maio, Maria Grazia Castagna

Source: Archives of Endocrinology and Metabolism, Vol 64, Iss 4, Pp 483-486 (2020)

Subject Terms: Diabetes insipidus, immunotherapy, durvalumab, tremelimumab, Medicine, Diseases of the endocrine glands. Clinical endocrinology, RC648-665

File Description: electronic resource

Relation: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S2359-39972020000400483&tlng=en; https://doaj.org/toc/2359-4292

Access URL: https://doaj.org/article/4c5fe0fb2ce94489ba3bb9d87c10c843

Immunotherapy of brain metastases: breaking a 'dogma'

Authors: Anna Maria Di Giacomo, Monica Valente, Alfonso Cerase, Maria Fortunata Lofiego, Francesca Piazzini, Luana Calabrò, Elisabetta Gambale, Alessia Covre, Michele Maio

Source: Journal of Experimental & Clinical Cancer Research, Vol 38, Iss 1, Pp 1-10 (2019)

Subject Terms: Brain metastases, Immune checkpoint(s), Cancer immunotherapy, Lung cancer, Magnetic resonance imaging, Melanoma, Neoplasms. Tumors. Oncology. Including cancer and carcinogens, RC254-282

File Description: electronic resource

Relation: http://link.springer.com/article/10.1186/s13046-019-1426-2; https://doaj.org/toc/1756-9966

Access URL: https://doaj.org/article/db9302128def4972b7b8e1ebf814732e

Stability Program in Dendritic Cell Vaccines: A 'Real-World' Experience in the Immuno-Gene Therapy Factory of Romagna Cancer Center

Authors: Elena Pancisi, Anna Maria Granato, Emanuela Scarpi, Laura Ridolfi, Silvia Carloni, Cinzia Moretti, Massimo Guidoboni, Francesco De Rosa, Sara Pignatta, Claudia Piccinini, Valentina Soldati, Luana Calabrò, Massimo Framarini, Monica Stefanelli, Jenny Bulgarelli, Marcella Tazzari, Francesca Fanini, Massimiliano Petrini

Source: Vaccines, Vol 10, Iss 7, p 999 (2022)

Subject Terms: immunotherapy, dendritic cell vaccine, quality control, ATMP, stability, Medicine

File Description: electronic resource

Relation: https://www.mdpi.com/2076-393X/10/7/999; https://doaj.org/toc/2076-393X

Access URL: https://doaj.org/article/81747b5ebaba429caba0e93b295c5085

Epigenetic Immune Remodeling of Mesothelioma Cells: A New Strategy to Improve the Efficacy of Immunotherapy

Authors: Maria Fortunata Lofiego, Sara Cannito, Carolina Fazio, Francesca Piazzini, Ornella Cutaia, Laura Solmonese, Francesco Marzani, Carla Chiarucci, Anna Maria Di Giacomo, Luana Calabrò, Sandra Coral, Michele Maio, Alessia Covre, on behalf of the EPigenetic Immune-Oncology Consortium Airc (EPICA) Investigators

Source: Epigenomes, Vol 5, Iss 4, p 27 (2021)

Subject Terms: epigenetic drugs, DNA methylation, immunotherapy, malignant pleural mesothelioma, Genetics, QH426-470, Biotechnology, TP248.13-248.65

File Description: electronic resource

Relation: https://www.mdpi.com/2075-4655/5/4/27; https://doaj.org/toc/2075-4655

Access URL: https://doaj.org/article/4873e483dc294f2192f580253fb9978d

Nivolumab in never-smokers with advanced squamous non-small cell lung cancer: Results from the Italian cohort of an expanded access program

Authors: Marina Chiara Garassino, Lucio Crinò, Annamaria Catino, Andrea Ardizzoni, Enrico Cortesi, Federico Cappuzzo, Paola Bordi, Luana Calabrò, Fausto Barbieri, Antonio Santo, Giuseppe Altavilla, Francesca Ambrosio, Enrico Mini, Enrico Vasile, Floriana Morgillo, Alessandro Scoppola, Carmelo Bengala, Alessandro Follador, Natale Tedde, Diana Giannarelli, Giuseppe Lo Russo, Fabiana Vitiello

Source: Tumor Biology, Vol 40 (2018)

Subject Terms: Neoplasms. Tumors. Oncology. Including cancer and carcinogens, RC254-282

File Description: electronic resource

Relation: https://doaj.org/toc/1423-0380

Access URL: https://doaj.org/article/a35d500325154acd853223249891e33f

Soluble NKG2D ligands are biomarkers associated with the clinical outcome to immune checkpoint blockade therapy of metastatic melanoma patients

Authors: Cristina Maccalli, Diana Giannarelli, Carla Chiarucci, Ornella Cutaia, Gianluca Giacobini, Wouter Hendrickx, Giovanni Amato, Diego Annesi, Davide Bedognetti, Maresa Altomonte, Riccardo Danielli, Luana Calabrò, Anna Maria Di Giacomo, Francesco M. Marincola, Giorgio Parmiani, Michele Maio

Source: OncoImmunology, Vol 6, Iss 7 (2017)

Subject Terms: cytotoxic t-lymphocyte antigen-4 (ctla-4), metastatic melanoma, nkg2d ligands, programmed cell death-1 (pd-1), t cell responses, Immunologic diseases. Allergy, RC581-607, Neoplasms. Tumors. Oncology. Including cancer and carcinogens, RC254-282

File Description: electronic resource

Relation: https://doaj.org/toc/2162-402X

Access URL: https://doaj.org/article/05691ff539e94d23badce601a4beb680

High levels of exosomes expressing CD63 and caveolin-1 in plasma of melanoma patients.

Authors: Mariantonia Logozzi, Angelo De Milito, Luana Lugini, Martina Borghi, Luana Calabrò, Massimo Spada, Maurizio Perdicchio, Maria Lucia Marino, Cristina Federici, Elisabetta Iessi, Daria Brambilla, Giulietta Venturi, Francesco Lozupone, Mario Santinami, Veronica Huber, Michele Maio, Licia Rivoltini, Stefano Fais

Source: PLoS ONE, Vol 4, Iss 4, p e5219 (2009)

Subject Terms: Medicine, Science

File Description: electronic resource

Relation: http://europepmc.org/articles/PMC2667632?pdf=render; https://doaj.org/toc/1932-6203

Access URL: https://doaj.org/article/777e9b167fd447db947c5d1cba838ee7

From antiquity to contemporary times: how olive oil by-products and waste water can contribute to health

Authors: Adriana Albini, Francesca Albini, Paola Corradino, Laura Dugo, Luana Calabrone, Douglas M. Noonan

Source: Frontiers in Nutrition, Vol 10 (2023)

Subject Terms: olive oil, olive mill waste water, polyphenols, cancer prevention, cardiotoxicity, angiogenesis, Nutrition. Foods and food supply, TX341-641

File Description: electronic resource

Relation: https://www.frontiersin.org/articles/10.3389/fnut.2023.1254947/full; https://doaj.org/toc/2296-861X

Access URL: https://doaj.org/article/f4f13912a1c04af5be1a41ea7028aa5e

The multifaceted nature of IL-10: regulation, role in immunological homeostasis and its relevance to cancer, COVID-19 and post-COVID conditions

Authors: Valentina Carlini, Douglas M. Noonan, Eslam Abdalalem, Delia Goletti, Clementina Sansone, Luana Calabrone, Adriana Albini

Source: Frontiers in Immunology, Vol 14 (2023)

Subject Terms: IL-10, STAT3, cytokine storm, alarmin, COVID - 19, Post-COVID, Immunologic diseases. Allergy, RC581-607

File Description: electronic resource

Relation: https://www.frontiersin.org/articles/10.3389/fimmu.2023.1161067/full; https://doaj.org/toc/1664-3224

Access URL: https://doaj.org/article/9b6d1a7747024ee2b5c3202d7f9476e1

An Olive Oil Mill Wastewater Extract Improves Chemotherapeutic Activity Against Breast Cancer Cells While Protecting From Cardiotoxicity

Authors: Nadia Benedetto, Luana Calabrone, Karolina Gutmańska, Nicoletta Macrì, Maria Grazia Cerrito, Riccardo Ricotta, Giuseppe Pelosi, Antonino Bruno, Douglas M. Noonan, Adriana Albini

Source: Frontiers in Cardiovascular Medicine, Vol 9 (2022)

Subject Terms: chemotherapy, breast cancer, polyphenol, olive, cardiomyocyte, Diseases of the circulatory (Cardiovascular) system, RC666-701

File Description: electronic resource

Relation: https://www.frontiersin.org/articles/10.3389/fcvm.2022.867867/full; https://doaj.org/toc/2297-055X

Access URL: https://doaj.org/article/8a0d16237ba44942a76f4129f7933f93

Skeletonema marinoi Extracts and Associated Carotenoid Fucoxanthin Downregulate Pro-Angiogenic Mediators on Prostate Cancer and Endothelial Cells

Authors: Luana Calabrone, Valentina Carlini, Douglas M. Noonan, Marco Festa, Cinzia Ferrario, Danilo Morelli, Debora Macis, Angelo Fontana, Luigi Pistelli, Christophe Brunet, Clementina Sansone, Adriana Albini

Source: Cells, Vol 12, Iss 7, p 1053 (2023)

Subject Terms: diatoms, fucoxanthin, prostate, endothelial, prevention, Cytology, QH573-671

File Description: electronic resource

Relation: https://www.mdpi.com/2073-4409/12/7/1053; https://doaj.org/toc/2073-4409

Access URL: https://doaj.org/article/6f2b4c50b539464fb42a065213a75b19

The Carotenoid Diatoxanthin Modulates Inflammatory and Angiogenesis Pathways In Vitro in Prostate Cancer Cells

Authors: Clementina Sansone, Luigi Pistelli, Luana Calabrone, Angelo Del Mondo, Angelo Fontana, Marco Festa, Douglas M. Noonan, Adriana Albini, Christophe Brunet

Source: Antioxidants, Vol 12, Iss 2, p 359 (2023)

Subject Terms: chemoprevention, oxidative stress-induced cell death, xanthophyll, angiogenesis, microalgae, diatoms, Therapeutics. Pharmacology, RM1-950

File Description: electronic resource

Relation: https://www.mdpi.com/2076-3921/12/2/359; https://doaj.org/toc/2076-3921

Access URL: https://doaj.org/article/442b14ba711943d095889c5cd235a931

Bone metastases and immunotherapy in patients with advanced non-small-cell lung cancer

Authors: Lorenza Landi, Federica D’Incà, Alain Gelibter, Rita Chiari, Francesco Grossi, Angelo Delmonte, Antonio Passaro, Diego Signorelli, Francesco Gelsomino, Domenico Galetta, Diana Giannarelli, Hector Soto Parra, Gabriele Minuti, Marcello Tiseo, Maria Rita Migliorino, Francesco Cognetti, Luca Toschi, Paolo Bidoli, Francovito Piantedosi, Luana Calabro’, Federico Cappuzzo

Source: Journal for ImmunoTherapy of Cancer, Vol 7, Iss 1, Pp 1-9 (2019)

Subject Terms: Bone metastases, Nivolumab, Immunotherapy, PD-L1, Non-small-cell lung cancer, Neoplasms. Tumors. Oncology. Including cancer and carcinogens, RC254-282

File Description: electronic resource

Relation: http://link.springer.com/article/10.1186/s40425-019-0793-8; https://doaj.org/toc/2051-1426

Access URL: https://doaj.org/article/2272c4a411464ed7ab0c54c8cd9b40b4

Preliminary Evidence for IL-10-Induced ACE2 mRNA Expression in Lung-Derived and Endothelial Cells: Implications for SARS-Cov-2 ARDS Pathogenesis

Authors: Adriana Albini, Luana Calabrone, Valentina Carlini, Nadia Benedetto, Michele Lombardo, Antonino Bruno, Douglas M. Noonan

Source: Frontiers in Immunology, Vol 12 (2021)

Subject Terms: ACE2, IL-10, COVID-19 pro-inflammatory cytokines, SARS-COV-2, cytokine storm, metformin, Immunologic diseases. Allergy, RC581-607

File Description: electronic resource

Relation: https://www.frontiersin.org/articles/10.3389/fimmu.2021.718136/full; https://doaj.org/toc/1664-3224

Access URL: https://doaj.org/article/06e81f5eec174733b5fc11b336186712

The Microalgal Diatoxanthin Inflects the Cytokine Storm in SARS-CoV-2 Stimulated ACE2 Overexpressing Lung Cells

Authors: Clementina Sansone, Luigi Pistelli, Angelo Del Mondo, Luana Calabrone, Angelo Fontana, Douglas M. Noonan, Adriana Albini, Christophe Brunet

Source: Antioxidants, Vol 11, Iss 8, p 1515 (2022)

Subject Terms: carotenoids, ACE2, COVID-19, inflammation, cytokine, antiviral, Therapeutics. Pharmacology, RM1-950

File Description: electronic resource

Relation: https://www.mdpi.com/2076-3921/11/8/1515; https://doaj.org/toc/2076-3921

Access URL: https://doaj.org/article/9ebc352f30dd42febe0fd5d09afa4065