The homeodomain transcription factor Six3 regulates hypothalamic Pomc expression and its absence from POMC neurons induces hyperphagia and mild obesity in male mice

Authors: Yu, Hui, Chiang, Angelika, Rubinstein, Marcelo, Low, Malcolm J.

Source: In Molecular Metabolism September 2024 87

Kilohertz Frequency Stimulation of Renal Nerves for Modulating Blood Glucose Concentration in Diabetic Rats

Authors: Jiman, Ahmad A., Chhabra, Kavaljit H., Ratze, David C., Lewis, Alfor G., Cederna, Paul S., Seeley, Randy J., Low, Malcolm J., Bruns, Tim M.

Source: 2019 9th International IEEE/EMBS Conference on Neural Engineering (NER) Neural Engineering (NER), 2019 9th International IEEE/EMBS Conference on. :746-749 Mar, 2019

Relation: 2019 9th International IEEE/EMBS Conference on Neural Engineering (NER)

Melanocortin receptor agonist melanotan-II microinjected in the nucleus accumbens decreases appetitive and consumptive responding for food

Authors: Eliason, Nicole L., Martin, Lynne, Low, Malcolm J., Sharpe, Amanda L.

Source: In Neuropeptides December 2022 96

Adult-born proopiomelanocortin neurons derived from Rax-expressing precursors mitigate the metabolic effects of congenital hypothalamic proopiomelanocortin deficiency

Authors: Surbhi, Wittmann, Gábor, Low, Malcolm J., Lechan, Ronald M.

Source: In Molecular Metabolism November 2021 53

Hypothalamic POMC deficiency increases circulating adiponectin despite obesity

Authors: Yu, Hui, Chhabra, Kavaljit H., Thompson, Zoe, Jones, Graham L., Kiran, Sylee, Shangguan, Gary, Low, Malcolm J.

Source: In Molecular Metabolism May 2020 35

The transcriptional regulator PRDM12 is critical for Pomc expression in the mouse hypothalamus and controlling food intake, adiposity, and body weight

Authors: Hael, Clara E., Rojo, Daniela, Orquera, Daniela P., Low, Malcolm J., Rubinstein, Marcelo

Source: In Molecular Metabolism April 2020 34:43-53

Sex differences in the effect of bupropion and naltrexone combination on alcohol drinking in mice

Authors: Zhou, Yan, Leri, Francesco, Low, Malcolm J., Kreek, Mary Jeanne

Source: In Pharmacology, Biochemistry and Behavior June 2019 181:28-36

Hypothalamic POMC or MC4R deficiency impairs counterregulatory responses to hypoglycemia in mice

Authors: Tooke, Benjamin P., Yu, Hui, Adams, Jessica M., Jones, Graham L., Sutton-Kennedy, Talisha, Mundada, Lakshmi, Qi, Nathan R., Low, Malcolm J., Chhabra, Kavaljit H.

Source: In Molecular Metabolism February 2019 20:194-204

The Homeodomain Transcription Factor NKX2.1 Is Essential for the Early Specification of Melanocortin Neuron Identity and Activates Pomc Expression in the Developing Hypothalamus

Authors: Orquera, Daniela P., Tavella, M. Belén, de Souza, Flavio S. J., Nasif, Sofía, Low, Malcolm J., Rubinstein, Marcelo

Source: Journal of neuroscience. 39(21):4023-4035

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCRN620198650&indx=1&recIds=ETOCRN620198650

The G209R Mutant Mouse as a Model for Human PCSK1 Polyendocrinopathy

Authors: Shakya, Manita, Surbhi, Martin, Nicolle K, Arunagiri, Anoop, Martin, Martin G, Arvan, Peter, Low, Malcolm J, Lindberg, Iris

Source: Endocrinology. 163(5)

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100155426624.0x000001&indx=1&recIds=ETOCvdc_100155426624.0x000001

Treatment of Helicobacter Gastritis with IL-4 Requires Somatostatin

Authors: Zavros, Yana, Rathinavelu, Sivaprakash, Kao, John Y., Todisco, Andrea, Del Valle, John, Weinstock, Joel V., Low, Malcolm J., Merchant, Juanita L.

Source: Proceedings of the National Academy of Sciences of the United States of America, 2003 Oct . 100(22), 12944-12949.

Access URL: https://www.jstor.org/stable/3148066

Involvement of Bone Morphogenetic Protein 4 (BMP-4) in Pituitary Prolactinoma Pathogenesis through a Smad/Estrogen Receptor Crosstalk

Authors: Páez-Pereda, Marcelo, Giacomini, Damiana, Refojo, Damian, Nagashima, Alberto Carbia, Hopfner, Ursula, Grübler, Yvonne, Chervin, Alberto, Goldberg, Victoria, Goya, Rodolfo, Hentges, Shane T., Low, Malcolm J., Holsboer, Florian, Stalla, Günter K., Arzt, Eduardo

Source: Proceedings of the National Academy of Sciences of the United States of America, 2003 Feb 01. 100(3), 1034-1039.

Access URL: https://www.jstor.org/stable/3138280

Gastrin Induces Nuclear Export and Proteasome Degradation of Menin in Enteric Glial Cells

Authors: Sundaresan, Sinju, Meininger, Cameron A., Kang, Anthony J., Photenhauer, Amanda L., Hayes, Michael M., Sahoo, Nirakar, Grembecka, Jolanta, Cierpicki, Tomasz, Ding, Lin, Giordano, Thomas J., Else, Tobias, Madrigal, David J., Low, Malcolm J., Campbell, Fiona, Baker, Ann-Marie, Xu, Haoxing, Wright, Nicholas A., Merchant, Juanita L.

Source: In Gastroenterology December 2017 153(6):1555-1567

Lorcaserin improves glycemic control via a melanocortin neurocircuit

Authors: Burke, Luke K., Ogunnowo-Bada, Emmanuel, Georgescu, Teodora, Cristiano, Claudia, de Morentin, Pablo B. Martinez, Valencia Torres, Lourdes, D'Agostino, Giuseppe, Riches, Christine, Heeley, Nicholas, Ruan, Yue, Rubinstein, Marcelo, Low, Malcolm J., Myers, Martin G., Rochford, Justin J., Evans, Mark L., Heisler, Lora K.

Source: In Molecular Metabolism October 2017 6(10):1092-1102

Reduced renal sympathetic nerve activity contributes to elevated glycosuria and improved glucose tolerance in hypothalamus-specific Pomc knockout mice

Authors: Chhabra, Kavaljit H., Morgan, Donald A., Tooke, Benjamin P., Adams, Jessica M., Rahmouni, Kamal, Low, Malcolm J.

Source: In Molecular Metabolism October 2017 6(10):1274-1285

The Role of the D 2 Dopamine Receptor (D 2R ) in A 2A Adenosine Receptor (A 2A R)-Mediated Behavioral and Cellular Responses as Revealed by A 2A and D 2 Receptor Knockout Mice

Authors: Chen, Jiang-Fan, Moratalla, Rosario, Impagnatiello, Francesco, Grandy, David K., Cuellar, Beatriz, Rubinstein, Marcelo, Beilstein, Mark A., Hackett, Elizabeth, Fink, J. Stephen, Low, Malcolm J., Ongini, Ennio, Schwarzschild, Michael A.

Source: Proceedings of the National Academy of Sciences of the United States of America, 2001 Feb . 98(4), 1970-1975.

Access URL: https://www.jstor.org/stable/3054985

Dopamine-Dependent Synaptic Plasticity in Striatum during in vivo Development

Authors: Tang, Ka-Choi, Low, Malcolm J., Grandy, David K., Lovinger, David M.

Source: Proceedings of the National Academy of Sciences of the United States of America, 2001 Jan . 98(3), 1255-1260.

Access URL: https://www.jstor.org/stable/3054854

A mammalian tripartite enhancer cluster controls hypothalamic Pomc expression, food intake, and body weight.

Authors: Rojo, Daniela, Hael, Clara E., Soria, Agustina, de Souza, Flávio S. J., Low, Malcolm J., Franchin, Lucía F., Rubinstein, Marcelo

Source: Proceedings of the National Academy of Sciences of the United States of America; 4/30/2024, Vol. 121 Issue 18, p1-12, 38p

Subject Terms: GENE expression, FOOD consumption, BODY weight, MOLECULAR evolution, BINDING sites

Absence of Opioid Stress-Induced Analgesia in Mice Lacking β -Endorphin by Site-Directed Mutagenesis

Authors: Rubinstein, Marcelo, Mogil, Jeffrey S., Japón, Miguel, Chan, E. Cheng, Allen, Richard G., Low, Malcolm J.

Source: Proceedings of the National Academy of Sciences of the United States of America, 1996 Apr . 93(9), 3995-4000.

Access URL: https://www.jstor.org/stable/39182

Reprogramming the body weight set point by a reciprocal interaction of hypothalamic leptin sensitivity and Pomc gene expression reverts extreme obesity

Authors: Chhabra, Kavaljit H., Adams, Jessica M., Jones, Graham L., Yamashita, Miho, Schlapschy, Martin, Skerra, Arne, Rubinstein, Marcelo, Low, Malcolm J.

Source: In Molecular Metabolism October 2016 5(10):869-881