A longitudinal and transancestral analysis of DNA methylation patterns and disease activity in lupus patients

Authors: Patrick Coit, Lourdes Ortiz-Fernandez, Emily E. Lewis, W. Joseph McCune, Kathleen Maksimowicz-McKinnon, Amr H. Sawalha

Source: JCI Insight, Vol 5, Iss 22 (2020)

Subject Terms: Autoimmunity, Medicine

File Description: electronic resource

Relation: https://doaj.org/toc/2379-3708

Access URL: https://doaj.org/article/9bde268ed6c2483eb816f978eb9ea2a9

Epigenomics and transcriptomics of systemic sclerosis CD4+ T cells reveal long-range dysregulation of key inflammatory pathways mediated by disease-associated susceptibility loci

Authors: Tianlu Li, Lourdes Ortiz-Fernández, Eduardo Andrés-León, Laura Ciudad, Biola M. Javierre, Elena López-Isac, Alfredo Guillén-Del-Castillo, Carmen Pilar Simeón-Aznar, Esteban Ballestar, Javier Martin

Source: Genome Medicine, Vol 12, Iss 1, Pp 1-17 (2020)

Subject Terms: Systemic sclerosis, DNA methylation, Epigenetics, Long-distance regulation, Hi-C, Genetic susceptibility variants, Medicine, Genetics, QH426-470

File Description: electronic resource

Relation: http://link.springer.com/article/10.1186/s13073-020-00779-6; https://doaj.org/toc/1756-994X

Access URL: https://doaj.org/article/36de1b17ae30464c8c717b20a2be3b48

1507 The relationship between DNA methylation patterns and disease activity in a longitudinal multi-ancestral cohort of lupus patients

Authors: Patrick Coit, Amr H Sawalha, Kathleen Maksimowicz-McKinnon, Lourdes Ortiz-Fernández, Emily E Lewis, W Joseph McCune

Source: Lupus Science and Medicine, Vol 8, Iss Suppl 2 (2021)

Subject Terms: Immunologic diseases. Allergy, RC581-607

File Description: electronic resource

Relation: https://doaj.org/toc/2053-8790

Access URL: https://doaj.org/article/6dce7ca4c0f54daf95b51aa0a50ca848

Genetics of Behçet's Disease: Functional Genetic Analysis and Estimating Disease Heritability

Authors: Lourdes Ortiz-Fernández, Amr H. Sawalha

Source: Frontiers in Medicine, Vol 8 (2021)

Subject Terms: Behçet's disease, genetics, heritability, genetic risk score, epigenetic, Medicine (General), R5-920

File Description: electronic resource

Relation: https://www.frontiersin.org/articles/10.3389/fmed.2021.625710/full; https://doaj.org/toc/2296-858X

Access URL: https://doaj.org/article/abc55c7493a24d9d9db2763c38a4b9e2

Mutational profile of rare variants in inflammasome-related genes in Behçet disease: A Next Generation Sequencing approach

Authors: Sergio Burillo-Sanz, Marco-Antonio Montes-Cano, José-Raúl García-Lozano, Lourdes Ortiz-Fernández, Norberto Ortego-Centeno, Francisco-José García-Hernández, Gerard Espinosa, Genaro Graña-Gil, Juan Sánchez-Bursón, María Rosa Juliá, Roser Solans, Ricardo Blanco, Ana-Celia Barnosi-Marín, Ricardo Gómez De la Torre, Patricia Fanlo, Mónica Rodríguez-Carballeira, Luis Rodríguez-Rodríguez, Teresa Camps, Santos Castañeda, Juan-Jose Alegre-Sancho, Javier Martín, María Francisca González-Escribano

Source: Scientific Reports, Vol 7, Iss 1, Pp 1-9 (2017)

Subject Terms: Medicine, Science

File Description: electronic resource

Relation: https://doaj.org/toc/2045-2322

Access URL: https://doaj.org/article/a17410930c33440f8760e7431d185c48

Monogenic Lupus: A Developing Paradigm of Disease

Authors: Jessie M. Alperin, Lourdes Ortiz-Fernández, Amr H. Sawalha

Source: Frontiers in Immunology, Vol 9 (2018)

Subject Terms: lupus, monogenic, familial, genetic, mendelian, Immunologic diseases. Allergy, RC581-607

File Description: electronic resource

Relation: https://www.frontiersin.org/article/10.3389/fimmu.2018.02496/full; https://doaj.org/toc/1664-3224

Access URL: https://doaj.org/article/3ba3211e25ce4b91a25e49112305e6e1

Genetic Analysis with the Immunochip Platform in Behçet Disease. Identification of Residues Associated in the HLA Class I Region and New Susceptibility Loci.

Authors: Lourdes Ortiz-Fernández, Francisco-David Carmona, Marco-Antonio Montes-Cano, José-Raúl García-Lozano, Marta Conde-Jaldón, Norberto Ortego-Centeno, María Jesús Castillo, Gerard Espinosa, Genaro Graña-Gil, Juan Sánchez-Bursón, María Rosa Juliá, Roser Solans, Ricardo Blanco, Ana-Celia Barnosi-Marín, Ricardo Gómez de la Torre, Patricia Fanlo, Mónica Rodríguez-Carballeira, Luis Rodríguez-Rodríguez, Teresa Camps, Santos Castañeda, Juan-Jose Alegre-Sancho, Javier Martín, María Francisca González-Escribano

Source: PLoS ONE, Vol 11, Iss 8, p e0161305 (2016)

Subject Terms: Medicine, Science

File Description: electronic resource

Relation: http://europepmc.org/articles/PMC4993481?pdf=render; https://doaj.org/toc/1932-6203

Access URL: https://doaj.org/article/cd2a076877dd417cae555c6ef45b7407

Epistatic interaction of ERAP1 and HLA-B in Behçet disease: a replication study in the Spanish population.

Authors: Marta Conde-Jaldón, Marco Antonio Montes-Cano, José Raul García-Lozano, Lourdes Ortiz-Fernández, Norberto Ortego-Centeno, Rocío González-León, Gerard Espinosa, Genaro Graña-Gil, Juan Sánchez-Bursón, Miguel Angel González-Gay, Ana Celia Barnosi-Marín, Roser Solans, Patricia Fanlo, Mónica Rodríguez Carballeira, Teresa Camps, Santos Castañeda, Javier Martín, María Francisca González-Escribano

Source: PLoS ONE, Vol 9, Iss 7, p e102100 (2014)

Subject Terms: Medicine, Science

File Description: electronic resource

Relation: http://europepmc.org/articles/PMC4096596?pdf=render; https://doaj.org/toc/1932-6203

Access URL: https://doaj.org/article/40bb01c3d56f4162a6027a7e46ff5336