Topographic analysis of pancreatic cancer by TMA and digital spatial profiling reveals biological complexity with potential therapeutic implications

Authors: Victoria Bingham, Louise Harewood, Stephen McQuaid, Stephanie G. Craig, Julia F. Revolta, Chang S. Kim, Shambhavi Srivastava, Javier Quezada-Marín, Matthew P. Humphries, Manuel Salto-Tellez

Source: Scientific Reports, Vol 14, Iss 1, Pp 1-14 (2024)

Subject Terms: Pancreatic ductal adenocarcinoma, Topographic tissue microarrays, Image analysis, Biomarkers, Tumour heterogeneity, Digital spatial profiling, Medicine, Science

File Description: electronic resource

Relation: https://doaj.org/toc/2045-2322

Access URL: https://doaj.org/article/d25a41f56be2446d9bbeea882fd613c5

LINE retrotransposons characterize mammalian tissue-specific and evolutionarily dynamic regulatory regions

Authors: Maša Roller, Ericca Stamper, Diego Villar, Osagie Izuogu, Fergal Martin, Aisling M. Redmond, Raghavendra Ramachanderan, Louise Harewood, Duncan T. Odom, Paul Flicek

Source: Genome Biology, Vol 22, Iss 1, Pp 1-43 (2021)

Subject Terms: Regulatory evolution, Gene regulation, Promoters, Enhancers, Transposable elements, Long Interspersed Nuclear Elements (LINEs), Biology (General), QH301-705.5, Genetics, QH426-470

File Description: electronic resource

Relation: https://doaj.org/toc/1474-760X

Access URL: https://doaj.org/article/c5c4fa97e4e54a19aaaedaf410287007

Proteogenomics and Hi-C reveal transcriptional dysregulation in high hyperdiploid childhood acute lymphoblastic leukemia

Authors: Minjun Yang, Mattias Vesterlund, Ioannis Siavelis, Larissa H. Moura-Castro, Anders Castor, Thoas Fioretos, Rozbeh Jafari, Henrik Lilljebjörn, Duncan T. Odom, Linda Olsson, Naveen Ravi, Eleanor L. Woodward, Louise Harewood, Janne Lehtiö, Kajsa Paulsson

Source: Nature Communications, Vol 10, Iss 1, Pp 1-15 (2019)

Subject Terms: Science

File Description: electronic resource

Relation: https://doaj.org/toc/2041-1723

Access URL: https://doaj.org/article/8fb5db51725140f997f862673ee0cf51

Hi-C as a tool for precise detection and characterisation of chromosomal rearrangements and copy number variation in human tumours

Authors: Louise Harewood, Kamal Kishore, Matthew D. Eldridge, Steven Wingett, Danita Pearson, Stefan Schoenfelder, V. Peter Collins, Peter Fraser

Source: Genome Biology, Vol 18, Iss 1, Pp 1-11 (2017)

Subject Terms: Hi-C, Chromosome conformation capture, Cancer, Tumour, Glioblastoma, Anaplastic astrocytoma, Biology (General), QH301-705.5, Genetics, QH426-470

File Description: electronic resource

Relation: http://link.springer.com/article/10.1186/s13059-017-1253-8; https://doaj.org/toc/1474-760X

Access URL: https://doaj.org/article/6927c847dd604636bfaaaa54b97b4973

Genetic Analysis of 'PAX6-Negative' Individuals with Aniridia or Gillespie Syndrome.

Authors: Morad Ansari, Jacqueline Rainger, Isabel M Hanson, Kathleen A Williamson, Freddie Sharkey, Louise Harewood, Angela Sandilands, Jill Clayton-Smith, Helene Dollfus, Pierre Bitoun, Francoise Meire, Judy Fantes, Brunella Franco, Birgit Lorenz, David S Taylor, Fiona Stewart, Colin E Willoughby, Meriel McEntagart, Peng Tee Khaw, Carol Clericuzio, Lionel Van Maldergem, Denise Williams, Ruth Newbury-Ecob, Elias I Traboulsi, Eduardo D Silva, Mukhlis M Madlom, David R Goudie, Brian W Fleck, Dagmar Wieczorek, Juergen Kohlhase, Alice D McTrusty, Carol Gardiner, Christopher Yale, Anthony T Moore, Isabelle Russell-Eggitt, Lily Islam, Melissa Lees, Philip L Beales, Stephen J Tuft, Juan B Solano, Miranda Splitt, Jens Michael Hertz, Trine E Prescott, Deborah J Shears, Ken K Nischal, Martine Doco-Fenzy, Fabienne Prieur, I Karen Temple, Katherine L Lachlan, Giuseppe Damante, Danny A Morrison, Veronica van Heyningen, David R FitzPatrick

Source: PLoS ONE, Vol 11, Iss 4, p e0153757 (2016)

Subject Terms: Medicine, Science

File Description: electronic resource

Relation: http://europepmc.org/articles/PMC4849793?pdf=render; https://doaj.org/toc/1932-6203

Access URL: https://doaj.org/article/b653c7a9f55349049c0c5eae18e1736f

Structural variation-associated expression changes are paralleled by chromatin architecture modifications.

Authors: Nele Gheldof, Robert M Witwicki, Eugenia Migliavacca, Marion Leleu, Gérard Didelot, Louise Harewood, Jacques Rougemont, Alexandre Reymond

Source: PLoS ONE, Vol 8, Iss 11, p e79973 (2013)

Subject Terms: Medicine, Science

File Description: electronic resource

Relation: http://europepmc.org/articles/PMC3827143?pdf=render; https://doaj.org/toc/1932-6203

Access URL: https://doaj.org/article/646b4d9f7a25426b9df984162de41f61

Bilateral renal agenesis/hypoplasia/dysplasia (BRAHD): postmortem analysis of 45 cases with breakpoint mapping of two de novo translocations.

Authors: Louise Harewood, Monica Liu, Jean Keeling, Alan Howatson, Margo Whiteford, Peter Branney, Margaret Evans, Judy Fantes, David R Fitzpatrick

Source: PLoS ONE, Vol 5, Iss 8, p e12375 (2010)

Subject Terms: Medicine, Science

File Description: electronic resource

Relation: http://europepmc.org/articles/PMC2928268?pdf=render; https://doaj.org/toc/1932-6203

Access URL: https://doaj.org/article/71ac7198def24b3bb55ca7168275d3a7