Activity and inhibition of the SARS-CoV-2 Omicron nsp13 R392C variant using RNA duplex unwinding assays

Authors: Inniss, Nicole L., Rzhetskaya, Margarita, Ling-Hu, Ted, Lorenzo-Redondo, Ramon, Bachta, Kelly E., Satchell, Karla J.F., Hultquist, Judd F.

Source: In SLAS Discovery April 2024 29(3)

Integration of individualized and population-level molecular epidemiology data to model COVID-19 outcomes

Authors: Ling-Hu, Ted, Simons, Lacy M., Dean, Taylor J., Rios-Guzman, Estefany, Caputo, Matthew T., Alisoltani, Arghavan, Qi, Chao, Malczynski, Michael, Blanke, Timothy, Jennings, Lawrence J., Ison, Michael G., Achenbach, Chad J., Larkin, Paige M., Kaul, Karen L., Lorenzo-Redondo, Ramon, Ozer, Egon A., Hultquist, Judd F.

Source: In Cell Reports Medicine 16 January 2024 5(1)

Release of P-TEFb from the Super Elongation Complex promotes HIV-1 latency reversal.

Authors: Cisneros, William J.^1,2, Soliman, Shimaa H. A.³, Walter, Miriam¹, Simons, Lacy M.^1,2, Cornish, Daphne^1,2, De Fabritiis, Simone³, Halle, Ariel W.^1,2, Kim, Eun-Young¹, Wolinsky, Steven M.¹, Lorenzo-Redondo, Ramon^1,2, Shilatifard, Ali³, Hultquist, Judd F.^1,2, judd.hultquist@northwestern.edu

Source: PLoS Pathogens; 9/11/2024, Vol. 20 Issue 9, p1-32, 32p

Inflammatory responses revealed through HIV infection of microglia-containing cerebral organoids.

Authors: Narasipura, Srinivas D., Zayas, Janet P., Ash, Michelle K., Reyes, Anjelica F., Shull, Tanner, Gambut, Stephanie, Szczerkowski, James L. A., McKee, Charia, Schneider, Jeffrey R., Lorenzo-Redondo, Ramon, Al-Harthi, Lena, Mamede, João I.

Source: Journal of Neuroinflammation; 2/10/2025, Vol. 22 Issue 1, p1-21, 21p

Subject Terms: PLURIPOTENT stem cells, NEUROGLIA, MEDICAL sciences, HIV infections, COMPLEMENT activation

Transcriptome-wide changes in gene expression, splicing, and lncRNAs in response to a live attenuated dengue virus vaccine

Authors: Kim, Eun-Young, Che, Yan, Dean, Hansi J., Lorenzo-Redondo, Ramon, Stewart, Michael, Keller, Caroline K., Whorf, Daniel, Mills, Dawson, Dulin, Nikita N., Kim, Tiffany, Votoupal, Megan, Walter, Miriam, Fernandez-Sesma, Ana, Kim, Heejin, Wolinsky, Steven M.

Source: In Cell Reports 8 February 2022 38(6)

Viral whole-genome sequencing to assess impact of universal masking on SARS-CoV-2 transmission among pediatric healthcare workers

Authors: Kociolek, Larry K., Patel, Ami B., Hultquist, Judd F., Ozer, Egon A., Simons, Lacy M., McHugh, Matthew, Muller, William J., Lorenzo-Redondo, Ramon

Source: Infection control and hospital epidemiology. 43(10):1408-1412

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCRN631594242&indx=1&recIds=ETOCRN631594242

Severity of Illness Caused by Severe Acute Respiratory Syndrome Coronavirus 2 Variants of Concern in Children: A Single-Center Retrospective Cohort Study

Authors: Edward, Priya R, Lorenzo-Redondo, Ramon, Reyna, Megan E, Simons, Lacy M, Hultquist, Judd F, Patel, Ami B, Ozer, Egon A, Muller, William J, Heald-Sargent, Taylor, McHugh, Matthew, Dean, Taylor, Dalal, Raj M, John, Jordan, Manz, Shannon C, Kociolek, Larry K

Source: Journal of the Pediatric Infectious Diseases Society. 11(10):440-447

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100163278291.0x000001&indx=1&recIds=ETOCvdc_100163278291.0x000001

Rapid and Sensitive Detection of Antigen from SARS-CoV-2 Variants of Concern by a Multivalent Minibinder-Functionalized Nanomechanical Sensor

Authors: Agarwal, Dilip Kumar, Hunt, Andrew C., Shekhawat, Gajendra S., Carter, Lauren, Chan, Sidney, Wu, Kejia, Cao, Longxing, Baker, David, Lorenzo-Redondo, Ramon, Ozer, Egon A.

Source: Analytical chemistry. 94(23):8105-8109

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCRN629555119&indx=1&recIds=ETOCRN629555119

Screening Students and Staff for Asymptomatic Coronavirus Disease 2019 in Chicago Schools

Authors: Edward, Priya R., Reyna, Megan E., Daly, Mary Kate, Hultquist, Judd F., Muller, William J., Ozer, Egon A., Lorenzo-Redondo, Ramon, Seed, Patrick C., Simons, Lacy M., Sheehan, Karen, Staples, Jacinta, Kociolek, Larry

Source: In The Journal of Pediatrics December 2021 239:74-80

Anatomic Distribution of Intravenously Injected IgG Takes Approximately 1 Week to Achieve Stratum Corneum Saturation in Vaginal Tissues

Authors: Carias, Ann M., Schneider, Jeffrey R., Madden, Patrick, Lorenzo-Redondo, Ramon, Araínga, Mariluz, Pegu, Amarendra, Cianci, Gianguido C., Marie, Danijela, Villinger, Francois, Mascola, John R.

Source: Journal of immunology. 207(2):505-511

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCRN627133595&indx=1&recIds=ETOCRN627133595

PET/CT Targeted Tissue Sampling Reveals Intravenously Administered HGN194 IgG1 Affects HIV Distribution after Rectal Exposure.

Authors: Taylor, Roslyn A., Xiao, Sixia, Carias, Ann M., McRaven, Michael D., Thakkar, Divya N., Araínga, Mariluz, Lorenzo-Redondo, Ramon, Allen, Edward J., Rogers, Kenneth A., Kumarapperuma, Sidath C., Gong, Siqi, Anderson, Meegan R., Thomas, Yanique, Madden, Patrick J., Corti, Davide, Cameroni, Elisabetta, Lanzavecchia, Antonio, Goins, Beth, Fox, Peter, Villinger, Francois J.

Source: AIDS Research & Human Retroviruses; Nov2024, Vol. 40 Issue 11, p637-648, 12p

A clade of SARS-CoV-2 viruses associated with lower viral loads in patient upper airways

Authors: Lorenzo-Redondo, Ramon, Nam, Hannah H., Roberts, Scott C., Simons, Lacy M., Jennings, Lawrence J., Qi, Chao, Achenbach, Chad J., Hauser, Alan R., Ison, Michael G., Hultquist, Judd F., Ozer, Egon A.

Source: In eBioMedicine December 2020 62

Impact of chemokine C–C ligand 27, foreskin anatomy and sexually transmitted infections on HIV-1 target cell availability in adolescent South African males

Authors: Gray, Clive M., O'Hagan, Kyle L., Lorenzo-Redondo, Ramon, Olivier, Abraham J., Amu, Sylvie, Chigorimbo-Murefu, Nyaradzo, Harryparsad, Rushil, Sebaa, Shorok, Maziya, Lungile, Dietrich, Janan, Otwombe, Kennedy, Martinson, Neil, Ferrian, Selena, Mkhize, Nonhlanhla N., Lewis, David A., Lang, Dirk, Carias, Ann M., Jaspan, Heather B., Wilson, Douglas P.K., McGilvray, Marcus, Cianci, Gianguido C., Anderson, Meegan R., Dinh, Minh H., Williamson, Anna-Lise, Passmore, Jo-Ann S., Chiodi, Francesca, Hope, Thomas J.

Source: In Mucosal Immunology January 2020 13(1):118-127

Large library docking for novel SARS‐CoV‐2 main protease non‐covalent and covalent inhibitors

Authors: Fink, Elissa A., Bardine, Conner, Gahbauer, Stefan, Singh, Isha, Detomasi, Tyler C., White, Kris, Gu, Shuo, Wan, Xiaobo, Chen, Jun, Ary, Beatrice, Glenn, Isabella, O'Connell, Joseph, O'Donnell, Henry, Fajtová, Pavla, Lyu, Jiankun, Vigneron, Seth, Young, Nicholas J., Kondratov, Ivan S., Alisoltani, Arghavan, Simons, Lacy M., Lorenzo‐Redondo, Ramon, Ozer, Egon A., Hultquist, Judd F., O'Donoghue, Anthony J., Moroz, Yurii S., Taunton, Jack, Renslo, Adam R., Irwin, John J., García‐Sastre, Adolfo, Shoichet, Brian K., Craik, Charles S.

Source: Protein science. 32(8)

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100188554973.0x000001&indx=1&recIds=ETOCvdc_100188554973.0x000001

Elite controllers and lessons learned for HIV-1 cure

Authors: Lopez-Galindez, Cecilio, Pernas, Maria, Casado, Concepcion, Olivares, Isabel, Lorenzo-Redondo, Ramon

Source: In Current Opinion in Virology October 2019 38:31-36

Molecular epidemiology in the HIV and SARS-CoV-2 pandemics

Authors: Lorenzo-Redondo, Ramon, Ozer, Egon A., Achenbach, Chad J., D'Aquila, Richard T., Hultquist, Judd F.

Source: Current opinion in HIV & AIDS. 16(1):11-24

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100112483711.0x000001&indx=1&recIds=ETOCvdc_100112483711.0x000001

Assessment of Virological Contributions to COVID-19 Outcomes in a Longitudinal Cohort of Hospitalized Adults

Authors: Simons, Lacy M, Lorenzo-Redondo, Ramon, Gibson, Meg, Kinch, Sarah L, Vandervaart, Jacob P, Reiser, Nina L, Eren, Mesut, Lux, Elizabeth, McNally, Elizabeth M, Tambur, Anat R, Vaughan, Douglas E, Bachta, Kelly E R, Demonbreun, Alexis R, Satchell, Karla J F, Achenbach, Chad J, Ozer, Egon A, Ison, Michael G, Hultquist, Judd F

Source: Open forum infectious diseases. 9(3)

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100142913503.0x000001&indx=1&recIds=ETOCvdc_100142913503.0x000001

De novo emergence of SARS‐CoV‐2 spike mutations in immunosuppressed patients

Authors: Simons, Lacy M., Ozer, Egon A., Gambut, Stephanie, Dean, Taylor J., Zhang, Li, Bhimalli, Pavan, Schneider, Jeffrey R., Mamede, João I., Ison, Michael G., Karmali, Reem, Gordon, Leo I., Lorenzo‐Redondo, Ramon, Hultquist, Judd F.

Source: Transplant infectious disease. 24(6)

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100185685397.0x000001&indx=1&recIds=ETOCvdc_100185685397.0x000001

Incidence and Clinical Characteristics of Severe Acute Respiratory Syndrome Coronavirus 2 Infection After Vaccination in Children

Authors: Reyna, Megan E., Edward, Priya R., Ozer, Egon A., Simons, Lacy M., Hultquist, Judd F., Lorenzo-Redondo, Ramon, Patel, Ami B., Kociolek, Larry K.

Source: Journal of pediatrics. 251:196-201.e4

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100176903643.0x000001&indx=1&recIds=ETOCvdc_100176903643.0x000001

Longitudinal Analysis of SARS-CoV-2 Vaccine Breakthrough Infections Reveals Limited Infectious Virus Shedding and Restricted Tissue Distribution

Authors: Ke, Ruian, Martinez, Pamela P, Smith, Rebecca L, Gibson, Laura L, Achenbach, Chad J, McFall, Sally, Qi, Chao, Jacob, Joshua, Dembele, Etienne, Bundy, Camille, Simons, Lacy M, Ozer, Egon A, Hultquist, Judd F, Lorenzo-Redondo, Ramon, Opdycke, Anita K, Hawkins, Claudia, Murphy, Robert L, Mirza, Agha, Conte, Madison, Gallagher, Nicholas, Luo, Chun Huai, Jarrett, Junko, Conte, Abigail, Zhou, Ruifeng, Farjo, Mireille, Rendon, Gloria, Fields, Christopher J, Wang, Leyi, Fredrickson, Richard, Baughman, Melinda E, Chiu, Karen K, Choi, Hannah, Scardina, Kevin R, Owens, Alyssa N, Broach, John, Barton, Bruce, Lazar, Peter, Robinson, Matthew L, Mostafa, Heba H, Manabe, Yukari C, Pekosz, Andrew, McManus, David D, Brooke, Christopher B

Source: Open forum infectious diseases. 9(7)

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100155694382.0x000001&indx=1&recIds=ETOCvdc_100155694382.0x000001