Bioactivation of cinnamic alcohol in a reconstructed human epidermis model and evaluation of sensitizing potency of the identified metabolites

Authors: Lorena Ndreu, Josefine Carlsson, David J. Ponting, Ida B. Niklasson, E. Johanna L. Stéen, Lukas McHugh, Niamh M. O’Boyle, Kristina Luthman, Ann-Therese Karlberg, Isabella Karlsson

Source: Frontiers in Toxicology, Vol 6 (2024)

Subject Terms: cinnamic alcohol, biotransformation, reconstructed human epidermis, pOH-cinnamic alcohol, pOH-cinnamic aldehyde, cinnamic sulfate, Toxicology. Poisons, RA1190-1270

File Description: electronic resource

Relation: https://www.frontiersin.org/articles/10.3389/ftox.2024.1398852/full; https://doaj.org/toc/2673-3080

Access URL: https://doaj.org/article/3a70b102db8b43ccb2651c13464648e5

Haptenation of Macrophage Migration Inhibitory Factor: A Potential Biomarker for Contact Hypersensitivity

Authors: Lorena Ndreu, Samantha Sasse, Ann-Therese Karlberg, Isabella Karlsson

Source: Frontiers in Toxicology, Vol 4 (2022)

Subject Terms: allergic contact dermatitis (ACD), biomarkers, contact hypersensitivity (CHS), high resolution mass spectrometry (HRMS), macrophage migration inhibitory factor (MIF), tetramethylrhodamine isothiocyanate (TRITC), Toxicology. Poisons, RA1190-1270

File Description: electronic resource

Relation: https://www.frontiersin.org/articles/10.3389/ftox.2022.856614/full; https://doaj.org/toc/2673-3080

Access URL: https://doaj.org/article/bd2d5da060fe4fa4b84604bc43881e14