Exploring high-throughput drug sensitivity testing in neuroblastoma cell lines and patient-derived tumor organoids in the era of precision medicine

Authors: Langenberg, Karin P.S. ^{a, ⁎, 1, 2}, van Hooff, Sander R. ^{a, ⁎, 1, 3}, Koopmans, Bianca ^a, Strijker, Josephine G.M. ^a, Kholosy, Waleed M. ^{a, 4}, Ober, Kimberley ^a, Zwijnenburg, Danny A. ^{b, 5}, van der Hoek, Jessica J.F. ^a, Keller, Kaylee M. ^a, Vernooij, Lindy ^a, Schild, Linda G. ^a, Looze, Eleonora J. ^a, Ebus, Marli E. ^a, Essing, Anke H.W. ^a, Vree, Paula de ^a, Tas, Michelle L. ^{a, 6}, Matser, Yvette A.H. ^a, Wienke, Judith ^a, Volckmann, Richard ^b, Tops, Bastiaan B.J. ^a, Kester, Lennart A. ^{a, 7}, Badloe, Shashi ^a, Hehir-Kwa, Jayne Y. ^a, Kemmeren, Patrick ^{a, c, 8}, Goemans, Bianca F. ^{a, 9}, Zwaan, C. Michel ^a, Oehme, Ina ^{d, e}, Jäger, Nathalie ^d, Witt, Olaf ^{d, e, f, 10}, van Eijkelenburg, Natasha K.A. ^{a, 11}, Dierselhuis, Miranda P. ^a, Tytgat, Godelieve A.M. ^a, Wijnen, Marc H.W. ^a, van Noesel, Max M. ^{a, g}, de Krijger, Ronald R. ^{a, h, 12}, Eising, Selma ^a, Koster, Jan ^b, Dolman, Emmy M. ^{a, 13}, Molenaar, Jan J. ^{a, i}

Source: In European Journal of Cancer 11 March 2025 218

Limited clinical activity of palbociclib and ribociclib monotherapy in advanced cancers with cyclin D‐CDK4/6 pathway alterations in the Dutch DRUP and Australian MoST trials

Authors: Zeverijn, Laurien J., Looze, Eleonora J., Thavaneswaran, Subotheni, Berge Henegouwen, J. Maxime, Simes, Robert J., Hoes, Louisa R., Sjoquist, Katrin M., Wijngaart, Hanneke, Sebastian, Lucille, Geurts, Birgit S., Lee, Chee K., Wit, Gijsbrecht F., Espinoza, David, Roepman, Paul, Lin, Frank P., Jansen, Anne M. L., Leng, Wendy W. J., Noort, Vincent, Leek, Lindsay V. M., Vos, Filip Y. F. L., Herpen, Carla M. L., Gelderblom, Hans, Verheul, Henk M. W., Thomas, David M., Voest, Emile E.

Source: International journal of cancer. 153(7):1413-1422

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100192727357.0x000001&indx=1&recIds=ETOCvdc_100192727357.0x000001

Implementation of paediatric precision oncology into clinical practice: The Individualized Therapies for Children with cancer program ‘iTHER’

Authors: Langenberg, Karin P.S., Meister, Michael T., Bakhuizen, Jette J., Boer, Judith M., van Eijkelenburg, Natasha K.A., Hulleman, Esther, Ilan, Uri, Looze, Eleonora J., Dierselhuis, Miranda P., van der Lugt, Jasper, Breunis, Willemijn, Schild, Linda G., Ober, Kimberley, van Hooff, Sander R., Scheijde-Vermeulen, Marijn A., Hiemcke-Jiwa, Laura S., Flucke, Uta E., Kranendonk, Mariette E.G., Wesseling, Pieter, Sonneveld, Edwin, Punt, Simone, Boltjes, Arjan, van Dijk, Freerk, Verwiel, Eugene T.P., Volckmann, Richard, Hehir-Kwa, Jayne Y., Kester, Lennart A., Koudijs, Marco M.J., Waanders, Esme, Holstege, Frank C.P., Vormoor, H. Josef, Hoving, Eelco W., van Noesel, Max M., Pieters, Rob, Kool, Marcel, Stumpf, Miriam, Blattner-Johnson, Mirjam, Balasubramanian, Gnana P., Van Tilburg, Cornelis M., Jones, Barbara C., Jones, David T.W., Witt, Olaf, Pfister, Stefan M., Jongmans, Marjolijn C.J., Kuiper, Roland P., de Krijger, Ronald R., Wijnen, Marc H.W., den Boer, Monique L., Zwaan, C. Michel, Kemmeren, Patrick, Koster, Jan, Tops, Bastiaan B.J., Goemans, Bianca F., Molenaar, Jan J.

Source: In European Journal of Cancer November 2022 175:311-325

The Landscape of Pediatric Precision Oncology: Program Design, Actionable Alterations, and Clinical Trial Development.

Authors: Langenberg, Karin P. S.¹ (AUTHOR) e.j.looze@amsterdamumc.nl, Looze, Eleonora J.¹ (AUTHOR) j.j.molenaar@prinsesmaximacentrum.nl, Molenaar, Jan J.^1,2 (AUTHOR)

Source: Cancers. Sep2021, Vol. 13 Issue 17, p4324. 1p.

Subject Terms: *THERAPEUTIC use of antineoplastic agents, *BIOMARKERS, *COMBINATION drug therapy, *PEDIATRICS, *INDIVIDUALIZED medicine, *TUMORS in children, *HUMAN services programs, *MOLECULAR biology, *GENE expression profiling, *CANCER patient medical care, *IMMUNOTHERAPY