Molecular prediction of clinical response to anti‐PD‐1/anti‐PD‐L1 immune checkpoint inhibitors: New perspectives for precision medicine and mass spectrometry‐based investigations

Authors: Longuespée, Rémi, Theile, Dirk, Zörnig, Inka, Hassel, Jessica C., Lindner, Joshua Raoul, Haefeli, Walter E., Fresnais, Margaux

Source: International journal of cancer. 153(2):252-264

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Tumor resistance to ferroptosis driven by Stearoyl-CoA Desaturase-1 (SCD1) in cancer cells and Fatty Acid Biding Protein-4 (FABP4) in tumor microenvironment promote tumor recurrence

Authors: Luis, Géraldine, Godfroid, Adrien, Nishiumi, Shin, Cimino, Jonathan, Blacher, Silvia, Maquoi, Erik, Wery, Coline, Collignon, Alice, Longuespée, Rémi, Montero-Ruiz, Laetitia, Dassoul, Isabelle, Maloujahmoum, Naima, Pottier, Charles, Mazzucchelli, Gabriel, Depauw, Edwin, Bellahcène, Akeila, Yoshida, Masaru, Noel, Agnès, Sounni, Nor Eddine

Source: In Redox Biology July 2021 43

Exploring Structural and Molecular Features of Sciatic Nerve Lesions in Diabetic Neuropathy: Unveiling Pathogenic Pathways and Targets.

Authors: Schwarz, Daniel, Le Marois, Maxime, Sturm, Volker, Peters, Andreas S., Longuespée, Rémi, Helm, Dominic, Schneider, Martin, Eichmüller, Bastian, Hidmark, Asa S., Fischer, Manuel, Kender, Zoltan, Schwab, Constantin, Hausser, Ingrid, Weis, Joachim, Dihlmann, Susanne, Böckler, Dittmar, Bendszus, Martin, Heiland, Sabine, Herzig, Stephan, Nawroth, Peter P.

Source: Diabetes; Jan2025, Vol. 74 Issue 1, p65-74, 10p

Subject Terms: MAGNETIC resonance neurography, TYPE 2 diabetes, DIABETIC neuropathies, SCIATIC nerve, COMPLEMENT activation

Desorption/Ionization-MS Methods for Drug Quantification in Biological Matrices and Their Validation Following Regulatory Guidance

Authors: Fresnais, Margaux, Burhenne, Jürgen, Haefeli, Walter E., Longuespée, Rémi

Source: Analytical chemistry. 93(19):7152-7163

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Approaching sites of action of drugs in clinical pharmacology: New analytical options and their challenges

Authors: Longuespée, Rémi, Theile, Dirk, Fresnais, Margaux, Burhenne, Jürgen, Weiss, Johanna, Haefeli, Walter E.

Source: British journal of clinical pharmacology. 87(3):858-874

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MALDImID: Spatialomics R package and Shiny app for more specific identification of MALDI imaging proteolytic peaks using LC‐MS/MS‐based proteomic biomarker discovery data

Authors: Oliveira, Cristiano, Longuespée, Rémi

Source: Proteomics. 23(12)

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Insulinoma-associated Protein 1 (INSM1) in Thoracic Tumors is Less Sensitive but More Specific Compared With Synaptophysin, Chromogranin A, and CD56

Authors: Kriegsmann, Katharina, Zgorzelski, Christiane, Kazdal, Daniel, Cremer, Martin, Muley, Thomas, Winter, Hauke, Longuespée, Rémi, Kriegsmann, Jörg, Warth, Arne, Kriegsmann, Mark

Source: Applied immunohistochemistry & molecular morphology. 28(3):237-242

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Subclonal evolution of pulmonary adenocarcinomas delineated by spatially distributed somatic mitochondrial mutations

Authors: Kazdal, Daniel, Harms, Alexander, Endris, Volker, Penzel, Roland, Oliveira, Cristiano, Kriegsmann, Mark, Longuespée, Rémi, Winter, Hauke, Schneider, Marc A., Muley, Thomas, Pfarr, Nicole, Weichert, Wilko, Stenzinger, Albrecht, Warth, Arne

Source: In Lung Cancer December 2018 126:80-88

Multi-Enzymatic Limited Digestion: The Next-Generation Sequencing for Proteomics?

Authors: Morsa, Denis, Baiwir, Dominique, La Rocca, Raphaël, Zimmerman, Tyler A., Hanozin, Emeline, Grifnée, Elodie, Longuespée, Rémi, Meuwis, Marie-Alice, Smargiasso, Nicolas, De Paüw, Edwin

Source: Journal of proteome research. 18(6):2501-2513

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Programmed cell death ligand 1 (PD-L1, CD274) in cholangiocarcinoma – correlation with clinicopathological data and comparison of antibodies

Authors: Kriegsmann, Mark, Roessler, Stephanie, Kriegsmann, Katharina, Renner, Marcus, Longuespée, Rémi, Albrecht, Thomas, Loeffler, Moritz, Singer, Stephan, Mehrabi, Arianeb, Vogel, Monika, Pathil, Anita, Köhler, Bruno, Springfeld, Christoph, Rupp, Christian, Weiss, Karl, Goeppert, Benjamin

Source: BMC cancer. 19(1):1-10

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Typing of colon and lung adenocarcinoma by high throughput imaging mass spectrometry

Authors: Kriegsmann, Mark, Longuespée, Rémi, Wandernoth, Petra, Mohanu, Cristina, Lisenko, Katharina, Weichert, Wilko, Warth, Arne, Dienemann, Hendrik, De Pauw, Edwin, Katzenberger, Tiemo, Aust, Daniela, Baretton, Gustavo, Kriegsmann, Joerg, Casadonte, Rita

Source: In BBA - Proteins and Proteomics July 2017 1865(7):858-864

Human peripheral blood mononuclear cells: A review of recent proteomic applications

Authors: Alexovič, Michal, Lindner, Joshua Raoul, Bober, Peter, Longuespée, Rémi, Sabo, Ján, Davalieva, Katarina

Source: Proteomics. 22(15-16)

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An optimized MALDI MSI protocol for spatial detection of tryptic peptides in fresh frozen prostate tissue

Authors: Høiem, Therese S., Andersen, Maria K., Martin‐Lorenzo, Marta, Longuespée, Rémi, Claes, Britt S.R., Nordborg, Anna, Dewez, Frédéric, Balluff, Benjamin, Giampà, Marco, Sharma, Animesh, Hagen, Lars, Heeren, Ron M.A., Bathen, Tone F., Giskeødegård, Guro F., Krossa, Sebastian, Tessem, May‐Britt

Source: Proteomics. 22(10)

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Proteomic investigation of human cystic echinococcosis in the liver

Authors: Longuespée, Rémi, Casadonte, Rita, Kriegsmann, Mark, Wandernoth, Petra, Lisenko, Katharina, Mazzucchelli, Gabriel, Becker, Michael, Kriegsmann, Jörg

Source: In Molecular & Biochemical Parasitology January 2017 211:9-14

Mass spectrometry in pathology – Vision for a future workflow

Authors: Kriegsmann, Jörg, Casadonte, Rita, Kriegsmann, Katharina, Longuespée, Rémi, Kriegsmann, Mark

Source: Pathology, research and practice. 214(8):1057-1063

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MALDI Imaging Combined with Laser Microdissection-Based Microproteomics for Protein Identification: Application to Intratumor Heterogeneity Studies

Authors: Longuespée, Rémi, Alberts, Deborah, Baiwir, Dominique, Mazzucchelli, Gabriel, Smargiasso, Nicolas, De Pauw, Edwin

Source: Methods in molecular biology. 1788:297-312

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Analysis of the proliferative activity in lung adenocarcinomas with specific driver mutations

Authors: Kriegsmann, Mark, Harms, Alexander, Kazdal, Daniel, Fischer, Sebastian, Stenzinger, Albrecht, Leichsenring, Jonas, Penzel, Roland, Longuespée, Rémi, Kriegsmann, Katharina, Muley, Thomas, Safi, Seyer, Warth, Arne

Source: Pathology, research and practice. 214(3):408-416

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Laser Microdissection-Based Microproteomics of Formalin-Fixed and Paraffin-Embedded (FFPE) Tissues

Authors: Longuespée, Rémi, Baiwir, Dominique, Mazzucchelli, Gabriel, Smargiasso, Nicolas, De Pauw, Edwin

Source: Methods in molecular biology. 1723:19-32

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Rapid detection of 2-hydroxyglutarate in frozen sections of IDH mutant tumors by MALDI-TOF mass spectrometry

Authors: Longuespée, Rémi, Wefers, Annika, De Vita, Elena, Miller, Aubry, Reuss, David, Wick, Wolfgang, Herold-Mende, Christel, Kriegsmann, Mark, Schirmacher, Peter, von Deimling, Andreas, Pusch, Stefan

Source: Acta neuropathologica communications. 6(1):1-9

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Expression of HMB45, MelanA and SOX10 is rare in non-small cell lung cancer

Authors: Kriegsmann, Mark, Kriegsmann, Katharina, Harms, Alexander, Longuespée, Rémi, Zgorzelski, Christiane, Leichsenring, Jonas, Muley, Thomas, Winter, Hauke, Kazdal, Daniel, Goeppert, Benjamin, Warth, Arne

Source: Diagnostic pathology. 13(1):1-6

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