Stabilized designs of the malaria adhesin protein PvRBP2b for use as a potential diagnostic for Plasmodium vivax

Authors: D Sa, Jaison ^{1, 2}, Krauss, Lucas ³, Smith, Lauren ^{1, 2}, D'Andrea, Laura ^{1, 2}, Chan, Li-Jin ^{1, 2}, Abraham, Anju ¹, Kiernan-Walker, Nicholas ¹, Mazhari, Ramin ^{1, 2}, Lamont, Macie ¹, Lim, Pailene S. ¹, Sattabongkot, Jetsumon ⁴, Lacerda, Marcus VG. ⁵, Wini, Lyndes ⁶, Mueller, Ivo ^{1, 2}, Longley, Rhea J. ^{1, 2, 4}, Pymm, Phillip ^{1, 2}, Fleishman, Sarel J. ³, Tham, Wai-Hong ^{1, 2, 7, ∗}

Source: In Journal of Biological Chemistry March 2025 301(3)

Primaquine for uncomplicated Plasmodium vivax malaria in children younger than 15 years: a systematic review and individual patient data meta-analysis

Authors: Adhikari, Bipin, Alam, Mohammad Shafiul, Anstey, Nicholas M, Assefa, Ashenafi, Baird, J Kevin, Boyd, Sarah C, Chau, Nguyen H, Day, Nicholas PJ, Degaga, Tamiru Shibiru, Dondorp, Arjen M, Erhart, Annette, Ferreira, Marcelo U, Ghimire, Prakash, Khan, Wasif A, Ley, Benedikt, Mekuria, Asrat H, Mueller, Ivo, Naadim, Mohammad N, Nosten, Francois, Price, David J, Pukrittayakamee, Sasithon, Rowland, Mark, Sattabongkot, Jetsumon, SuarezKurtz, Guilherme, Sutanto, Inge, von Seidlein, Lorenz, William, Timothy, Woodrow, Charles J, Woyessa, Adugna, Commons, Robert J ^{*, *}, Rajasekhar, Megha ^*, Allen, Elizabeth N, Yilma, Daniel, Chotsiri, Palang, Abreha, Tesfay, Adam, Ishag, Awab, Ghulam Rahim, Barber, Bridget E, Brasil, Larissa W, Chu, Cindy S, Cui, Liwang, Edler, Peta, Gomes, Margarete do Socorro M, Gonzalez‑Ceron, Lilia, Grigg, Matthew J, Hamid, Muzamil Mahdi Abdel, Hwang, Jimee, Karunajeewa, Harin, Lacerda, Marcus V G, Ladeia-Andrade, Simone, Leslie, Toby, Longley, Rhea J, Monteiro, Wuelton Marcelo, Pasaribu, Ayodhia Pitaloka, Poespoprodjo, Jeanne Rini, Richmond, Caitlin L, Rijal, Komal Raj, Taylor, Walter R J, Thanh, Pham Vinh, Thriemer, Kamala, Vieira, José Luiz F, White, Nicholas J, Zuluaga-Idarraga, Lina M, Workman, Lesley J, Tarning, Joel, Stepniewska, Kasia, Guerin, Philippe J, Simpson, Julie A, Barnes, Karen I, Price, Ric N

Source: In The Lancet Child & Adolescent Health November 2024 8(11):798-808

Effect of primaquine dose on the risk of recurrence in patients with uncomplicated Plasmodium vivax: a systematic review and individual patient data meta-analysis

Authors: Adhikari, Bipin, Anstey, Nicholas M, Assefa, Ashenafi, Boyd, Sarah C, Chau, Nguyen Hoang, Day, Nicholas PJ, Degaga, Tamiru Shibiru, Dondorp, Arjen M, Erhart, Annette, Ferreira, Marcelo Urbano, Ghimire, Prakash, Green, Justin A, Koh, Gavin CKW, Mekuria, Asrat Hailu, Mueller, Ivo, Naadim, Mohammad Nader, Nelwan, Erni J, Nosten, Francois, Price, David J, Sattabongkot, Jetsumon, Stepniewska, Kasia, von Seidlein, Lorenz, William, Timothy, Woodrow, Charles J, Woyessa, Adugna, Commons, Robert J ^{*, *}, Rajasekhar, Megha ^*, Edler, Peta, Abreha, Tesfay, Awab, Ghulam R, Baird, J Kevin, Barber, Bridget E, Chu, Cindy S, Cui, Liwang, Daher, André, Gonzalez-Ceron, Lilia, Grigg, Matthew J, Hwang, Jimee, Karunajeewa, Harin, Lacerda, Marcus V G, Ladeia-Andrade, Simone, Lidia, Kartini, Llanos-Cuentas, Alejandro, Longley, Rhea J, Pereira, Dhelio B, Pasaribu, Ayodhia P, Pukrittayakamee, Sasithon, Rijal, Komal R, Sutanto, Inge, Taylor, Walter R J, Thanh, Pham V, Thriemer, Kamala, Vieira, José Luiz F, Watson, James A, Zuluaga-Idarraga, Lina M, White, Nicholas J, Guerin, Philippe J, Simpson, Julie A, Price, Ric N

Source: In The Lancet Infectious Diseases February 2024 24(2):172-183

Serology for Plasmodium vivax surveillance: A novel approach to accelerate towards elimination

Authors: Tayipto, Yanie, Liu, Zoe, Mueller, Ivo, Longley, Rhea J.

Source: In Parasitology International April 2022 87

Primaquine for uncomplicated Plasmodium vivaxmalaria in children younger than 15 years: a systematic review and individual patient data meta-analysis

Authors: Commons, Robert J, Rajasekhar, Megha, Allen, Elizabeth N, Yilma, Daniel, Chotsiri, Palang, Abreha, Tesfay, Adam, Ishag, Awab, Ghulam Rahim, Barber, Bridget E, Brasil, Larissa W, Chu, Cindy S, Cui, Liwang, Edler, Peta, Gomes, Margarete do Socorro M, Gonzalez‑Ceron, Lilia, Grigg, Matthew J, Hamid, Muzamil Mahdi Abdel, Hwang, Jimee, Karunajeewa, Harin, Lacerda, Marcus V G, Ladeia-Andrade, Simone, Leslie, Toby, Longley, Rhea J, Monteiro, Wuelton Marcelo, Pasaribu, Ayodhia Pitaloka, Poespoprodjo, Jeanne Rini, Richmond, Caitlin L, Rijal, Komal Raj, Taylor, Walter R J, Thanh, Pham Vinh, Thriemer, Kamala, Vieira, José Luiz F, White, Nicholas J, Zuluaga-Idarraga, Lina M, Workman, Lesley J, Tarning, Joel, Stepniewska, Kasia, Guerin, Philippe J, Simpson, Julie A, Barnes, Karen I, Price, Ric N, Adhikari, Bipin, Alam, Mohammad Shafiul, Anstey, Nicholas M, Assefa, Ashenafi, Baird, J Kevin, Boyd, Sarah C, Chau, Nguyen H, Day, Nicholas PJ, Degaga, Tamiru Shibiru, Dondorp, Arjen M, Erhart, Annette, Ferreira, Marcelo U, Ghimire, Prakash, Khan, Wasif A, Ley, Benedikt, Mekuria, Asrat H, Mueller, Ivo, Naadim, Mohammad N, Nosten, Francois, Price, David J, Pukrittayakamee, Sasithon, Rowland, Mark, Sattabongkot, Jetsumon, SuarezKurtz, Guilherme, Sutanto, Inge, von Seidlein, Lorenz, William, Timothy, Woodrow, Charles J, Woyessa, Adugna

Source: The Lancet Child & Adolescent Health; November 2024, Vol. 8 Issue: 11 p798-808, 11p

MAM 2024: Malaria in a changing world.

Authors: Longley, Rhea J.^1,2,3 (AUTHOR) longley.r@wehi.edu.au, Malinga, Josephine^1,4 (AUTHOR) josephine.malinga@swisstph.ch, Hesping, Eva^1,2,5 (AUTHOR) hesping.e@wehi.edu.au, Sutanto, Edwin^1,6 (AUTHOR) e.sutanto@exeins.org, DonVito, Sophia M.^1,7 (AUTHOR) Sophia.Donvito1@lshtm.ac.uk, Kucharski, Michal^1,8,9 (AUTHOR) mkucharski@ntu.edu.sg, Oyong, Damian A.^1,10 (AUTHOR) damian.oyong@burnet.edu.au, Verhoef, Julie M.J.^1,11 (AUTHOR) Julie.Verhoef@radboudumc.nl, Du, Esrah^1,12 (AUTHOR) edu@g.harvard.edu, Villasis, Elizabeth^1,13,14 (AUTHOR) ELIZABETH.VILLASIS.M@upch.pe, Mwikali, Kioko^1,15 (AUTHOR) KMwikali@kemri-wellcome.org

Source: Trends in Parasitology. May2024, Vol. 40 Issue 5, p355-361. 7p.

Subject Terms: *MALARIA

Using serological diagnostics to characterize remaining high-incidence pockets of malaria in forest-fringe Cambodia.

Authors: Grimée, Mathilde, Tacoli, Costanza, Sandfort, Mirco, Obadia, Thomas, Taylor, Aimee R., Vantaux, Amélie, Robinson, Leanne J., Lek, Dysoley, Longley, Rhea J., Mueller, Ivo, Popovici, Jean, White, Michael T., Witkowski, Benoît

Source: Malaria Journal; 2/15/2024, Vol. 23 Issue 1, p1-12, 12p

Subject Terms: MALARIA, PLASMODIUM vivax, FACTOR analysis, SEROCONVERSION, SURVIVAL analysis (Biometry)

Geographic Terms: CAMBODIA

Sensitive detection of Plasmodium vivax malaria by the rotating-crystal magneto-optical method in Thailand.

Authors: Orbán, Ágnes¹ orbanag@gmail.com, Longley, Rhea J.^2,3,4, Sripoorote, Piyarat³, Maneechai, Nongnuj³, Nguitragool, Wang⁵, Butykai, Ádám¹, Mueller, Ivo^2,4,6, Sattabongkot, Jetsumon³, Karl, Stephan^7,8, Kézsmárki, István^1,9

Source: Scientific Reports. 9/17/2021, Vol. 11 Issue 1, p1-8. 8p.

Subject Terms: *PLASMODIUM vivax, *MALARIA diagnosis, *TROPHOZOITES, *PARASITES

Geographic Terms: THAILAND

IgG Antibody Responses Are Preferential Compared With IgM for Use as Serological Markers for Detecting Recent Exposure to Plasmodium vivax Infection

Authors: Longley, Rhea J, White, Michael T, Brewster, Jessica, Liu, Zoe S J, Bourke, Caitlin, Takashima, Eizo, Harbers, Matthias, Tham, Wai-Hong, Healer, Julie, Chitnis, Chetan E, Monteiro, Wuelton, Lacerda, Marcus, Sattabongkot, Jetsumon, Tsuboi, Takafumi, Mueller, Ivo

Source: Open forum infectious diseases. 8(6)

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100132929429.0x000001&indx=1&recIds=ETOCvdc_100132929429.0x000001

The Threshold of Protection from Liver-Stage Malaria Relies on a Fine Balance between the Number of Infected Hepatocytes and Effector CD8^+ T Cells Present in the Liver

Authors: Spencer, Alexandra J., Longley, Rhea J., Gola, Anita, Ulaszewska, Marta, Lambe, Teresa, Hill, Adrian V. S.

Source: Journal of immunology. 198(5):2006-2016

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCRN610105967&indx=1&recIds=ETOCRN610105967

High Efficacy of Primaquine Treatment for Plasmodium vivax in Western Thailand

Authors: Longley, Rhea J., Sripoorote, Piyarat, Chobson, Pornpimol, Saeseu, Teerawat, Sukasem, Chonlaphat, Phuanukoonnon, Suparat, Nguitragool, Wang, Mueller, Ivo, Sattabongkot, Jetsumon

Source: American journal of tropical medicine and hygiene. 95(5):1086-1089

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCRN608733008&indx=1&recIds=ETOCRN608733008

Mixed Vector Immunization With Recombinant Adenovirus and MVA Can Improve Vaccine Efficacy While Decreasing Antivector Immunity

Authors: Reyes-Sandoval, Arturo, Rollier, Christine S, Milicic, Anita, Bauza, Karolis, Cottingham, Matthew G, Tang, Choon-Kit, Dicks, Matthew D, Wang, Dong, Longley, Rhea J, Wyllie, David H, Hill, Adrian VS

Source: In Molecular Therapy August 2012 20(8):1633-1647

Using Serological Markers for the Surveillance of Plasmodium vivax Malaria: A Scoping Review.

Authors: Kartal, Lejla, Mueller, Ivo, Longley, Rhea J.

Source: Pathogens; Jun2023, Vol. 12 Issue 6, p791, 19p

Subject Terms: PLASMODIUM vivax, MALARIA, SEROLOGY, MOLECULAR diagnosis, SEROPREVALENCE

Identification of novel Plasmodium vivax proteins associated with protection against clinical malaria.

Authors: Ramin Mazhari, Eizo Takashima, Longley, Rhea J., Ruybal-Pesantez, Shazia, White, Michael T., Kanoi, Bernard N., Hikaru Nagaoka, Kiniboro, Benson, Siba, Peter, Takafumi Tsuboi, Mueller, Ivo

Source: Frontiers in Cellular & Infection Microbiology; 1/25/2023, Vol. 13, p01-09, 9p

Subject Terms: PLASMODIUM vivax, LIPID transfer protein, MALARIA, CARRIER proteins, PROTEINS

Geographic Terms: PAPUA New Guinea

Plasmodium vivax and Plasmodium falciparum infection dynamics: re-infections, recrudescences and relapses

Authors: White, Michael T., Karl, Stephan, Koepfli, Cristian, Longley, Rhea J., Hofmann, Natalie E., Wampfler, Rahel, Felger, Ingrid, Smith, Tom, Nguitragool, Wang, Sattabongkot, Jetsumon, Robinson, Leanne, Ghani, Azra, Mueller, Ivo

Source: Malaria journal. 17(1)

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100127194137.0x000001&indx=1&recIds=ETOCvdc_100127194137.0x000001

Longitudinal IgG antibody responses to Plasmodium vivax blood-stage antigens during and after acute vivax malaria in individuals living in the Brazilian Amazon.

Authors: Tashi, Tenzin, Upadhye, Aditi, Kundu, Prasun, Wu, Chunxiang, Menant, Sébastien, Soares, Roberta Reis, Ferreira, Marcelo U., Longley, Rhea J., Mueller, Ivo, Hoang, Quyen Q., Tham, Wai-Hong, Rayner, Julian C., Scopel, Kézia KG, Lima-Junior, Josué C., Tran, Tuan M.

Source: PLoS Neglected Tropical Diseases; 11/23/2022, Vol. 16 Issue 11, p1-16, 16p

Subject Terms: ANTIBODY formation, PLASMODIUM vivax, MALARIA, IMMUNOGLOBULIN G, ANTIGENS, TRYPANOSOMA

Geographic Terms: BRAZIL

Evaluating the technical feasibility of serological testing and treatment for Plasmodium vivaxin mobile at-risk of malaria Cambodian populations

Authors: Tacoli, Costanza, Thin, Sopheany, Ea, Malen, Khim, Nimol, Orban, Agnes, Lek, Dysoley, Longley, Rhea J., White, Michael, Robinson, Leanne J., Witkowski, Benoit, Mueller, Ivo, Popovici, Jean

Source: The Lancet Regional Health - Western Pacific; 20250101, Issue: Preprints

Naturally acquired antibody responses to more than 300 Plasmodium vivax proteins in three geographic regions.

Authors: Longley, Rhea J.^1,2,3, White, Michael T.^1,4, Takashima, Eizo⁵, Morita, Masayuki⁵, Kanoi, Bernard N.⁵, Li Wai Suen, Connie S. N.^1,2, Betuela, Inoni⁶, Kuehn, Andrea⁷, Sripoorote, Piyarat³, Franca, Camila T.^1,2, Siba, Peter⁶, Robinson, Leanne J.^1,2,6, Lacerda, Marcus^8,9, Sattabongkot, Jetsumon³, Tsuboi, Takafumi⁵, Mueller, Ivo^1,2,10 ivomueller@fastmail.fm

Source: PLoS Neglected Tropical Diseases. 9/11/2017, Vol. 11 Issue 9, p1-15. 15p.

Subject Terms: *PLASMODIUM vivax, *MALARIA treatment, *DIAGNOSIS

Geographic Terms: THAILAND, BRAZIL, PAPUA New Guinea

Asymptomatic Plasmodium vivax infections induce robust IgG responses to multiple blood-stage proteins in a low-transmission region of western Thailand.

Authors: Longley, Rhea J.^1,2,3, França, Camila T.^1,3, White, Michael T.^1,4, Kumpitak, Chalermpon², Sa-angchai, Patiwat⁵, Gruszczyk, Jakub¹, Hostetler, Jessica B.^6,7, Yadava, Anjali⁸, King, Christopher L.⁹, Fairhurst, Rick M.⁷, Rayner, Julian C.⁶, Wai-Hong Tham^1,3, Wang Nguitragool¹⁰, Sattabongkot, Jetsumon², Mueller, Ivo^1,3,11,12 ivomueller@fastmail.fm

Source: Malaria Journal. 4/28/2017, Vol. 16, p1-13. 13p. 2 Charts, 3 Graphs, 1 Map.

Subject Terms: *PLASMODIUM vivax, *INFECTION, *IMMUNOGLOBULIN G, *HUMORAL immunity, *IMMUNE response

Assessment of IgG3 as a serological exposure marker for Plasmodium vivax in areas with moderate-high malaria transmission intensity.

Authors: Yanie Tayipto, Rosado, Jason, Gamboa, Dionicia, White, Michael T., Kiniboro, Benson, Healer, Julie, Opi, D. Herbert, Beeson, James G., Takashima, Eizo, Tsuboi, Takafumi, Harbers, Matthias, Robinson, Leanne, Mueller, Ivo, Longley, Rhea J.

Source: Frontiers in Cellular & Infection Microbiology; 8/9/2022, Vol. 12, p1-14, 14p

Subject Terms: PLASMODIUM vivax, ANTIBODY formation, IMMUNOGLOBULIN G, MALARIA, IMMUNOGLOBULINS, ANTIGENS