Interaction between host G3BP and viral nucleocapsid protein regulates SARS-CoV-2 replication and pathogenicity

Authors: Yang, Zemin ^{1, 2, 13}, Johnson, Bryan A. ^{3, 4, 5, 13}, Meliopoulos, Victoria A. ⁶, Ju, Xiaohui ⁷, Zhang, Peipei ¹, Hughes, Michael P. ¹, Wu, Jinjun ^{1, 2}, Koreski, Kaitlin P. ¹, Clary, Jemma E. ¹, Chang, Ti-Cheng ⁸, Wu, Gang ⁸, Hixon, Jeff ⁹, Duffner, Jay ⁹, Wong, Kathy ⁹, Lemieux, Rene ⁹, Lokugamage, Kumari G. ³, Alvarado, R. Elias ³, Crocquet-Valdes, Patricia A. ¹⁰, Walker, David H. ¹⁰, Plante, Kenneth S. ^{3, 11}, Plante, Jessica A. ^{3, 11}, Weaver, Scott C. ^{3, 4, 11}, Kim, Hong Joo ¹, Meyers, Rachel ⁹, Schultz-Cherry, Stacey ⁶, Ding, Qiang ⁷, Menachery, Vineet D. ^{3, 11, ∗}, Taylor, J. Paul ^{1, 12, 14, ∗∗}

Source: In Cell Reports 26 March 2024 43(3)

QTQTN motif upstream of the furin-cleavage site plays a key role in SARS-CoV-2 infection and pathogenesis

Authors: Vu, Michelle N., Lokugamage, Kumari G., Plante, Jessica A., Scharton, Dionna, Bailey, Aaron O., Sotcheff, Stephanea, Swetnam, Daniele M., Johnson, Bryan A., Schindewolf, Craig, Alvarado, R. Elias, Crocquet-Valdes, Patricia A., Debbink, Kari, Weaver, Scott C., Walker, David H., Russell, William K., Routh, Andrew L., Plante, Kenneth S., Menachery, Vineet D.

Source: Proceedings of the National Academy of Sciences of the United States of America, 2022 Aug 01. 119(32), 1-7.

Access URL: https://www.jstor.org/stable/27171458

An Infectious cDNA Clone of SARS-CoV-2

Authors: Xie, Xuping, Muruato, Antonio, Lokugamage, Kumari G., Narayanan, Krishna, Zhang, Xianwen, Zou, Jing, Liu, Jianying, Schindewolf, Craig, Bopp, Nathen E., Aguilar, Patricia V., Plante, Kenneth S., Weaver, Scott C., Makino, Shinji, LeDuc, James W., Menachery, Vineet D., Shi, Pei-Yong

Source: In Cell Host & Microbe 13 May 2020 27(5):841-848

Interplay between coronavirus, a cytoplasmic RNA virus, and nonsense-mediated mRNA decay pathway

Authors: Wada, Masami, Lokugamage, Kumari G., Nakagawa, Keisuke, Narayanan, Krishna, Makino, Shinji

Source: Proceedings of the National Academy of Sciences of the United States of America, 2018 Oct . 115(43), E10157-E10166.

Access URL: https://www.jstor.org/stable/26532390

Coronavirus nonstructural protein 1: Common and distinct functions in the regulation of host and viral gene expression

Authors: Narayanan, Krishna, Ramirez, Sydney I., Lokugamage, Kumari G., Makino, Shinji

Source: In Virus Research 16 April 2015 202:89-100

Nucleocapsid mutations in SARS-CoV-2 augment replication and pathogenesis.

Authors: Johnson, Bryan A.¹, Zhou, Yiyang², Lokugamage, Kumari G.¹, Vu, Michelle N.¹, Bopp, Nathen³, Crocquet-Valdes, Patricia A.³, Kalveram, Birte¹, Schindewolf, Craig¹, Liu, Yang², Scharton, Dionna^1,4, Plante, Jessica A.^1,4, Xie, Xuping², Aguilar, Patricia^3,5, Weaver, Scott C.^1,4,5,6, Shi, Pei-Yong^2,4,5,6,7, Walker, David H.^3,5, Routh, Andrew L.^2,6, Plante, Kenneth S.^1,4, Menachery, Vineet D.^1,4,5, Vimenach@utmb.edu

Source: PLoS Pathogens; 6/21/2022, Vol. 18 Issue 6, p1-22, 22p

A nanoluciferase SARS-CoV-2 for rapid neutralization testing and screening of anti-infective drugs for COVID-19

Authors: Xie, Xuping, Muruato, Antonio E., Zhang, Xianwen, Lokugamage, Kumari G., Fontes-Garfias, Camila R., Zou, Jing, Liu, Jianying, Ren, Ping, Balakrishnan, Mini, Cihlar, Tomas, Tseng, Chien-Te K., Makino, Shinji, Menachery, Vineet D., Bilello, John P., Shi, Pei-Yong

Source: Nature communications. 11(1)

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100174469127.0x000001&indx=1&recIds=ETOCvdc_100174469127.0x000001

Mechanism of tripartite RNA genome packaging in Rift Valley fever virus

Authors: Terasaki, Kaori, Murakami, Shin, Lokugamage, Kumari G., Makino, Shinji, Palese, Peter

Source: Proceedings of the National Academy of Sciences of the United States of America, 2011 Jan 01. 108(2), 804-809.

Access URL: https://www.jstor.org/stable/25770862

Chimeric coronavirus-like particles carrying severe acute respiratory syndrome coronavirus (SCoV) S protein protect mice against challenge with SCoV

Authors: Lokugamage, Kumari G., Yoshikawa-Iwata, Naoko, Ito, Naoto, Watts, Douglas M., Wyde, Philip R., Wang, Nan, Newman, Patrick, Kent Tseng, Chien-Te, Peters, C.J., Makino, Shinji

Source: In Vaccine 2008 26(6):797-808

Spike mutation D614G alters SARS-CoV-2 fitness.

Authors: Plante, Jessica A., Liu, Yang, Liu, Jianying, Xia, Hongjie, Johnson, Bryan A., Lokugamage, Kumari G., Zhang, Xianwen, Muruato, Antonio E., Zou, Jing, Fontes-Garfias, Camila R., Mirchandani, Divya, Scharton, Dionna, Bilello, John P., Ku, Zhiqiang, An, Zhiqiang, Kalveram, Birte, Freiberg, Alexander N., Menachery, Vineet D., Xie, Xuping, Plante, Kenneth S.

Source: Nature; 4/1/2021, Vol. 592 Issue 7852, p116-121, 6p

Loss of furin cleavage site attenuates SARS-CoV-2 pathogenesis.

Authors: Johnson, Bryan A., Xie, Xuping, Bailey, Adam L., Kalveram, Birte, Lokugamage, Kumari G., Muruato, Antonio, Zou, Jing, Zhang, Xianwen, Juelich, Terry, Smith, Jennifer K., Zhang, Lihong, Bopp, Nathen, Schindewolf, Craig, Vu, Michelle, Vanderheiden, Abigail, Winkler, Emma S., Swetnam, Daniele, Plante, Jessica A., Aguilar, Patricia, Plante, Kenneth S.

Source: Nature; 3/11/2021, Vol. 591 Issue 7849, p293-299, 7p

Engineering SARS-CoV-2 using a reverse genetic system.

Authors: Xie, Xuping, Lokugamage, Kumari G., Zhang, Xianwen, Vu, Michelle N., Muruato, Antonio E., Menachery, Vineet D., Shi, Pei-Yong

Source: Nature Protocols; Mar2021, Vol. 16 Issue 3, p1761-1784, 24p

Type I Interferon Susceptibility Distinguishes SARS-CoV-2 from SARS-CoV.

Authors: Lokugamage, Kumari G.¹, Hage, Adam¹, de Vries, Maren², Valero-Jimenez, Ana M.², Schindewolf, Craig¹, Dittmann, Meike², Rajsbaum, Ricardo^1,3, Menachery, Vineet D.^1,3 Vimenach@utmb.edu

Source: Journal of Virology. Dec2020, Vol. 94 Issue 23, p1-13. 13p.

Subject Terms: *SARS-CoV-2, *SARS virus, *COVID-19, *DNA replication, *VIRAL proteins, *TYPE I interferons, *INFLUENZA viruses

SARS Coronavirus nsp1 Protein Induces Template-Dependent Endonucleolytic Cleavage of mRNAs: Viral mRNAs Are Resistant to nsp1-Induced RNA Cleavage.

Authors: Cheng Huang¹, Lokugamage, Kumari G.¹, Rozovics, Janet M.², Narayanan, Krishna¹, Semler, Bert L.², Makino, Shinji¹ shmakino@utmb.edu

Source: PLoS Pathogens. Dec2011, Vol. 7 Issue 12, Special section p1-18. 18p. 8 Diagrams, 3 Graphs.

Subject Terms: *CORONAVIRUSES, *SARS disease, *PROTEINS, *ENDONUCLEASES, *MESSENGER RNA

A two-pronged strategy to suppress host protein synthesis by SARS coronavirus Nsp1 protein.

Authors: Kamitani, Wataru^1,2, Huang, Cheng¹, Narayanan, Krishna¹, Lokugamage, Kumari G¹, Makino, Shinji¹, shmakino@utmb.edu

Source: Nature Structural & Molecular Biology; Nov2009, Vol. 16 Issue 11, p1134-1140, 7p, 8 Graphs

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Author Correction: Spike mutation D614G alters SARS-CoV-2 fitness.

Authors: Plante, Jessica A., Liu, Yang, Liu, Jianying, Xia, Hongjie, Johnson, Bryan A., Lokugamage, Kumari G., Zhang, Xianwen, Muruato, Antonio E., Zou, Jing, Fontes-Garfias, Camila R., Mirchandani, Divya, Scharton, Dionna, Bilello, John P., Ku, Zhiqiang, An, Zhiqiang, Kalveram, Birte, Freiberg, Alexander N., Menachery, Vineet D., Xie, Xuping, Plante, Kenneth S.

Source: Nature; 7/1/2021, Vol. 595 Issue 7865, pE1-E1, 1p

Author Correction: A nanoluciferase SARS-CoV-2 for rapid neutralization testing and screening of anti-infective drugs for COVID-19.

Authors: Xie, Xuping, Muruato, Antonio E., Zhang, Xianwen, Lokugamage, Kumari G., Fontes-Garfias, Camila R., Zou, Jing, Liu, Jianying, Ren, Ping, Balakrishnan, Mini, Cihlar, Tomas, Tseng, Chien-Te K., Makino, Shinji, Menachery, Vineet D., Bilello, John P., Shi, Pei-Yong

Source: Nature Communications; 6/21/2021, Vol. 12 Issue 1, p1-1, 1p

Subject Terms: COVID-19, NEUTRALIZATION tests, SARS-CoV-2, LUCIFERASES