Intraperitoneal administration of mRNA encoding interleukin-12 for immunotherapy in peritoneal carcinomatosis

Authors: Leire Arrizabalaga, Claudia Augusta Di Trani, Myriam Fernández-Sendin, Ángela Bella, Joan Salvador Russo-Cabrera, Celia Gomar, Nuria Ardaiz, Virginia Belsue, José González-Gomariz, Sara Zalba, Adrián Gil-Korilis, Maria J. Garrido, Ignacio Melero, Fernando Aranda, Pedro Berraondo

Source: Journal of Nanobiotechnology, Vol 23, Iss 1, Pp 1-15 (2025)

Subject Terms: mRNA, Peritoneal carcinomatosis, Locoregional treatment, Interleukin-12, Cancer immunotherapy, Biotechnology, TP248.13-248.65, Medical technology, R855-855.5

File Description: electronic resource

Relation: https://doaj.org/toc/1477-3155

Access URL: https://doaj.org/article/10c4e219807749ea8785150005a379bb

Y90 Radiation Segmentectomy versus Microwave Ablation for Hepatocellular Carcinoma in Locations Suboptimal for Percutaneous Ablation

Authors: Olivia Kola, John A. Cieslak, Nirav Chauhan, Priya Gupta, Pratik Shukla, Abhishek Kumar

Source: The Arab Journal of Interventional Radiology, Vol 09, Iss 01, Pp 025-033 (2025)

Subject Terms: ablation, hepatocellular carcinoma, locoregional therapy, microwave ablation, Y-90, yttrium, Medical physics. Medical radiology. Nuclear medicine, R895-920

File Description: electronic resource

Relation: https://doaj.org/toc/2542-7075; https://doaj.org/toc/2542-7083

Access URL: https://doaj.org/article/770c966b93c64b7c8d6e794cc64ff171

Adding Dexmedetomidine to Methylene Blue in Thoracic Paravertebral Block for Video-Assisted Lobectomy: A Case Series Study

Authors: Coppolino F, Brunetti S, Bottazzo LM, Cosenza G, Sansone P, Fiore M, Passavanti MB, Pota V, Pace MC

Source: Local and Regional Anesthesia, Vol Volume 17, Pp 99-105 (2024)

Subject Terms: locoregional anesthesia, paravertebral block, post-operative pain, thoracic surgery, Anesthesiology, RD78.3-87.3

File Description: electronic resource

Relation: https://www.dovepress.com/adding-dexmedetomidine-to-methylene-blue-in-thoracic-paravertebral-blo-peer-reviewed-fulltext-article-LRA; https://doaj.org/toc/1178-7112

Access URL: https://doaj.org/article/f1a6f9f77fdc487ebd87dc2e7952cf42

Patterns of breast cancer locoregional relapse, metastasis, and subtypes in Ghana

Authors: Gloria Agyekum Boaitey, Rachel Martini, Brian Stonaker, Ernest Osei Bonsu, Ernest Adjei, Ishmael Kyei, Mavis Bobie Ansah, Lisa Newman, Christian Obirikorang, Melissa B. Davis, Linda Ahenkorah Fondjo

Source: BMC Cancer, Vol 24, Iss 1, Pp 1-10 (2024)

Subject Terms: Breast cancer, Locoregional relapse, Metastasis, Subtypes, LMIC, Neoplasms. Tumors. Oncology. Including cancer and carcinogens, RC254-282

File Description: electronic resource

Relation: https://doaj.org/toc/1471-2407

Access URL: https://doaj.org/article/01c0ebac86b948fe9b4cc1c6a25a2665

Impact of periodic neck ultrasonography on locoregional disease control in surveillance after total thyroidectomy for patients with low- and intermediate-risk papillary thyroid carcinoma: a propensity score-matched study

Authors: Takahiro Inaishi, Dai Takeuchi, Takahiro Ichikawa, Gai Inaguma, Atsushi Hashizume, Masaki Okazaki, Norikazu Masuda, Toyone Kikumori

Source: Endocrine Journal, Vol 71, Iss 12, Pp 1135-1143 (2024)

Subject Terms: locoregional recurrence, papillary thyroid carcinoma, surveillance, total thyroidectomy, ultrasonography, Diseases of the endocrine glands. Clinical endocrinology, RC648-665

File Description: electronic resource

Relation: https://www.jstage.jst.go.jp/article/endocrj/71/12/71_EJ24-0194/_html/-char/en; https://doaj.org/toc/1348-4540

Access URL: https://doaj.org/article/1cc0454a9e304c17af3fbbd7cfdfc921

Co-occurring mutations identify prognostic subgroups of microsatellite stable colorectal cancer

Authors: Luís Nunes, Jakob Mørkved Stenersen, Kushtrim Kryeziu, Tobias Sjöblom, Bengt Glimelius, Ragnhild A. Lothe, Anita Sveen

Source: Molecular Cancer, Vol 23, Iss 1, Pp 1-7 (2024)

Subject Terms: CRC, Locoregional, Metastatic, MSS, Survival, Prognosis, Neoplasms. Tumors. Oncology. Including cancer and carcinogens, RC254-282

File Description: electronic resource

Relation: https://doaj.org/toc/1476-4598

Access URL: https://doaj.org/article/77059ecf6491416ab78186162728bb5b

Electrochemotherapy in the Locoregional Treatment of Metastatic Colorectal Liver Metastases: A Systematic Review

Authors: Pierluigi Barbieri, Alessandro Posa, Valentina Lancellotta, David C. Madoff, Alessandro Maresca, Patrizia Cornacchione, Luca Tagliaferri, Roberto Iezzi

Source: Current Oncology, Vol 31, Iss 11, Pp 7403-7413 (2024)

Subject Terms: electrochemotherapy, colorectal cancer, liver metastases, locoregional therapy, Neoplasms. Tumors. Oncology. Including cancer and carcinogens, RC254-282

File Description: electronic resource

Relation: https://www.mdpi.com/1718-7729/31/11/546; https://doaj.org/toc/1198-0052; https://doaj.org/toc/1718-7729

Access URL: https://doaj.org/article/b00be8e24a014513b898826250cf2429

Erector spinae plane block for cancer pain relief: a systematic review

Authors: Paolo Capuano, Antonietta Alongi, Gaetano Burgio, Gennaro Martucci, Antonio Arcadipane, Andrea Cortegiani

Source: Journal of Anesthesia, Analgesia and Critical Care, Vol 4, Iss 1, Pp 1-14 (2024)

Subject Terms: Cancer pain, Fascial plane blocks, Chronic pain, Pain managment, Locoregional anesthesia, Anesthesiology, RD78.3-87.3, Medical emergencies. Critical care. Intensive care. First aid, RC86-88.9

File Description: electronic resource

Relation: https://doaj.org/toc/2731-3786

Access URL: https://doaj.org/article/73ef4c0e9dd84e8b82ed9cffa6da8b03

Combined Nabpaclitaxel pressurized intraPeritoneal aerosol chemotherapy with systemic Nabpaclitaxel-Gemcitabine chemotherapy for pancreatic cancer peritoneal metastases: protocol of single-arm, open-label, phase II trial (Nab-PIPAC trial)

Authors: Di Giorgio Andrea, Ferracci Federica, Bagalà Cinzia, Carbone Carmine, Salvatore Lisa, Strippoli Antonia, Attalla El Halabieh Miriam, Abatini Carlo, Alfieri Sergio, Pacelli Fabio, Tortora Giampaolo

Source: Pleura and Peritoneum, Vol 9, Iss 3, Pp 121-129 (2024)

Subject Terms: peritoneal metastasis, pancreatic cancer, pipac, bidirectional chemotherapy, combined chemotherapy, locoregional chemotherapy, Medicine, Specialties of internal medicine, RC581-951

File Description: electronic resource

Relation: https://doaj.org/toc/2364-768X

Access URL: https://doaj.org/article/da90453cd10640728db2ddd61a8f87c0

Postoperative tumor bed radiation versus T-shaped field radiation in the treatment of locally advanced thoracic esophageal squamous cell carcinoma: a phase IIb multicenter randomized controlled trial

Authors: Ya Zeng, Jiancheng Li, Jingjun Ye, Gaohua Han, Wenguang Luo, Chaoyang Wu, Songbing Qin, Wendong Gu, Shengguang Zhao, Yufei Zhao, Bing Xia, Zhengfei Zhu, Xianghui Du, Yuan Liu, Jun Liu, Hongxuan Li, Jiaming Wang, Jindong Guo, Wen Yu, Qin Zhang, Changlu Wang, Wentao Fang, Zhigang Li, Xiaolong Fu, Xuwei Cai

Source: BMC Medicine, Vol 22, Iss 1, Pp 1-11 (2024)

Subject Terms: Locally advanced esophageal squamous cell carcinoma, Postoperative radiotherapy, Radiation volume, Locoregional control, Survival outcomes, Medicine

File Description: electronic resource

Relation: https://doaj.org/toc/1741-7015

Access URL: https://doaj.org/article/9d5aa4332c824b0182aa7ab9431004ba

Skeletal Muscle Index Changes on Locoregional Treatment Application After FOLFIRINOX and Survival in Pancreatic Cancer

Authors: Ji Hye Min, Jeong Il Yu, Seong Hyun Kim, Young Kon Kim, Kangpyo Kim, Hee Chul Park, Joon Oh Park, Jung Yong Hong, Kyu Taek Lee, Kwang Hyuck Lee, Jong Kyun Lee, Joo Kyung Park, Jin Ho Choi, Jin Seok Heo, In Woong Han, Hongbeom Kim, Sang Hyun Shin, So Jung Yoon, Sook‐young Woo

Source: Journal of Cachexia, Sarcopenia and Muscle, Vol 16, Iss 1, Pp n/a-n/a (2025)

Subject Terms: FOLFIRINOX, locoregional treatments, pancreatic ductal adenocarcinoma, sarcopenia, skeletal‐muscle‐index changes, Diseases of the musculoskeletal system, RC925-935, Human anatomy, QM1-695

File Description: electronic resource

Relation: https://doaj.org/toc/2190-5991; https://doaj.org/toc/2190-6009

Access URL: https://doaj.org/article/a1b2087901cd4f6eb0306db5b495792d

Enhanced efficacy of immune checkpoint inhibitors combined locoregional therapy and tyrosine kinase inhibitors in the treatment of unresectable hepatocellular carcinoma: A single - center retrospective study

Authors: Junfeng Bu, Zihan Li, Die Hu, Ling Lan, Jiwei Huang, Xin Wang, Qiu Li, Jin Zhou, Yong Zeng

Source: Frontiers in Oncology, Vol 15 (2025)

Subject Terms: unresectable hepatocellular carcinoma, locoregional therapy, tyrosine kinase inhibitor, immune checkpoint inhibitor, system therapy, Neoplasms. Tumors. Oncology. Including cancer and carcinogens, RC254-282

File Description: electronic resource

Relation: https://www.frontiersin.org/articles/10.3389/fonc.2025.1554711/full; https://doaj.org/toc/2234-943X

Access URL: https://doaj.org/article/146ef65b8cc34da895b611a00d0894d9

The INFLUENCE 3.0 model: Updated predictions of locoregional recurrence and contralateral breast cancer, now also suitable for patients treated with neoadjuvant systemic therapy

Authors: M.C. Van Maaren, T.A. Hueting, D.J.P. van Uden, M. van Hezewijk, L. de Munck, M.A.M. Mureau, P.A. Seegers, Q.J.M. Voorham, M.K. Schmidt, G.S. Sonke, C.G.M. Groothuis-Oudshoorn, S. Siesling

Source: Breast, Vol 79, Iss , Pp 103829- (2025)

Subject Terms: Breast cancer, Follow-up, Surveillance, Prediction, Locoregional recurrence, Contralateral breast cancer, Neoplasms. Tumors. Oncology. Including cancer and carcinogens, RC254-282

File Description: electronic resource

Relation: http://www.sciencedirect.com/science/article/pii/S0960977624001607; https://doaj.org/toc/1532-3080

Access URL: https://doaj.org/article/2694b70dbad34b3ab649535c9ac0aeed

Suppression of MCP-1, IFN-γ and IL-6 production of HNSCC ex vivo by pembrolizumab added to docetaxel and cisplatin (TP) exceeding those of TP alone is linked to improved survival

Authors: Jana Wellhausen, Louisa Röhl, Michael Berszin, Irene Krücken, Veit Zebralla, Markus Pirlich, Matthaeus Stoehr, Susanne Wiegand, Andreas Dietz, Theresa Wald, Gunnar Wichmann

Source: Frontiers in Immunology, Vol 15 (2025)

Subject Terms: PD-1:PD-L1 immune-checkpoint inhibitor (ICI) pembrolizumab, local and locoregional advanced head and neck squamous cell carcinoma (HNSCC), neoadjuvant (induction) chemotherapy, predictive assay for chemoresponse-evaluation, biomarker research, monocyte chemoattractant protein 1 (MCP-1, Immunologic diseases. Allergy, RC581-607

File Description: electronic resource

Relation: https://www.frontiersin.org/articles/10.3389/fimmu.2024.1473897/full; https://doaj.org/toc/1664-3224

Access URL: https://doaj.org/article/def9c76c6fa549e2af7333622468b965

Immunotherapy combined with chemotherapy without locoregional radiotherapy in de novo metastatic nasopharyngeal carcinoma: two case reports and a literature review

Authors: Yingna Gao, Xiaoqiong Shi, Jianqiao He, Hui Yao, Guoning Yu, Lin Zhao, Yi Ma, Hongliang Zheng, Minhui Zhu, Caiyun Zhang

Source: Frontiers in Immunology, Vol 15 (2025)

Subject Terms: immunotherapy, chemotherapy, de novo metastatic nasopharyngeal carcinoma (dmNPC), Epstein-Barr virus (EBV), locoregional radiotherapy, Immunologic diseases. Allergy, RC581-607

File Description: electronic resource

Relation: https://www.frontiersin.org/articles/10.3389/fimmu.2024.1467355/full; https://doaj.org/toc/1664-3224

Access URL: https://doaj.org/article/d0691304a86f46699e2038979340ca8b

Prognosis prediction of α-FAtE score for locoregional immunotherapy in hepatocellular carcinoma

Authors: Zehao Zheng, Renguo Guan, Rongce Zhao, Junyu Gan, Xinhao Xiong, Jing-wen Zou, Shaohua Li, Qiaoxuan Wang, Wei Wei, Jie Mei, Rongping Guo

Source: Frontiers in Immunology, Vol 15 (2025)

Subject Terms: hepatocellular carcinoma, locoregional therapy, immunotherapy, alpha-fetoprotein, alkaline phosphatase, eosinophil, Immunologic diseases. Allergy, RC581-607

File Description: electronic resource

Relation: https://www.frontiersin.org/articles/10.3389/fimmu.2024.1496095/full; https://doaj.org/toc/1664-3224

Access URL: https://doaj.org/article/43905b2a02bf4e4e8b5035ad308cc818

Is postoperative radiotherapy effective in patients with completely resected pathologic stage IIIA(N2) non-small cell lung cancer? High-risk populations should consider it

Authors: Shu-Xian Zhang, Chen-Chen Zhang, Run-Ping Hou, Xu-Wei Cai, Jun Liu, Wen Yu, Qin Zhang, Jin-Dong Guo, Chang-Lu Wang, Hong-Xuan Li, Zheng-Fei Zhu, Xiao-Long Fu, Wen Feng

Source: Clinical and Translational Radiation Oncology, Vol 50, Iss , Pp 100889- (2025)

Subject Terms: Non-small cell lung cancer, Stage IIIA(N2), Postoperative radiotherapy, High risk of locoregional recurrence, Medical physics. Medical radiology. Nuclear medicine, R895-920, Neoplasms. Tumors. Oncology. Including cancer and carcinogens, RC254-282

File Description: electronic resource

Relation: http://www.sciencedirect.com/science/article/pii/S2405630824001666; https://doaj.org/toc/2405-6308

Access URL: https://doaj.org/article/6c63a7c22d084f47bb37a7af914544bb

An Optimal Strategy for Individualized Drug Delivery Therapy: A Molecular Communication Inspired Waveform Design Perspective

Authors: Wang, Dongze, Sun, Yue, Xiao, Yue, Chen, Yifan

Source: 2021 43rd Annual International Conference of the IEEE Engineering in Medicine & Biology Society (EMBC) Engineering in Medicine & Biology Society (EMBC), 2021 43rd Annual International Conference of the IEEE. :866-869 Nov, 2021

Relation: 2021 43rd Annual International Conference of the IEEE Engineering in Medicine & Biology Society (EMBC)

Portal vein tumor thrombosis in hepatocellular carcinoma patients: Is it the end?

Authors: Walaa Abdelhamed, Hend Shousha, Mohamed El-Kassas

Source: Liver Research, Vol 8, Iss 3, Pp 141-151 (2024)

Subject Terms: Hepatocellular carcinoma (HCC), Portal vein tumor thrombosis (PVTT), Staging, Systemic therapies, Locoregional treatment, Immunotherapy, Diseases of the digestive system. Gastroenterology, RC799-869

File Description: electronic resource

Relation: http://www.sciencedirect.com/science/article/pii/S2542568424000436; https://doaj.org/toc/2542-5684

Access URL: https://doaj.org/article/0a485adec1b34749b96133a23bf52e4f

Cure can be achieved by conversion to microwave ablation following atezolizumab-bevacizumab therapy in unresectable hepatocellular carcinoma

Authors: Rene John D. Febro, Engelbert Simon S. Perillo, Akemi A. Kimura, Stephen N. Wong

Source: Journal of Liver Cancer, Vol 24, Iss 2, Pp 234-242 (2024)

Subject Terms: microwave ablation, tyrosine kinase inhibitors, immune checkpoint inhibitors, locoregional therapy, combination, Internal medicine, RC31-1245

File Description: electronic resource

Relation: http://www.e-jlc.org/upload/pdf/jlc-2024-05-23.pdf; https://doaj.org/toc/2288-8128; https://doaj.org/toc/2383-5001

Access URL: https://doaj.org/article/69487178e5e144bca20b5eb2227d0134