Heterogeneous nuclear ribonucleoprotein F deficiency in mouse podocyte promotes podocytopathy mediated by methyltransferase-like 14 nuclear translocation resulting in Sirtuin 1 gene inhibition

Authors: Liao, Min-Chun, Lo, Chao-Sheng, Pang, Yu-Chao, Yang, Wen-Xia, Su, Ke, Zhao, Xin-Ping, Miyata, Kana N., Peng, Junzheng, Ingelfinger, Julie R., Chan, John S.D., Zhang, Shao-Ling

Source: In Translational Research May 2024 267:1-9

Comparison of the effects of insulin and SGLT2 inhibitor on the Renal Renin-Angiotensin system in type 1 diabetes mice

Authors: Miyata, Kana N., Zhao, Shuiling, Wu, Chin-Han, Lo, Chao-Sheng, Ghosh, Anindya, Chenier, Isabelle, Filep, Janos G., Ingelfinger, Julie R., Zhang, Shao-Ling, Chan, John S.D.

Source: In Diabetes Research and Clinical Practice April 2020 162

Increased urinary excretion of hedgehog interacting protein (uHhip) in early diabetic kidney disease

Authors: Miyata, Kana N., Zhao, Xin-Ping, Chang, Shiao-Ying, Liao, Min-Chun, Lo, Chao-Sheng, Chenier, Isabelle, Ethier, Jean, Cailhier, Jean-Francois, Lattouf, Jean-Baptiste, Troyanov, Stephan, Chiasson, Jean-Louis, Ingelfinger, Julie R., Chan, John S.D., Zhang, Shao-Ling

Source: In Translational Research March 2020 217:1-10

Heterogeneous Nuclear Ribonucleoprotein F Mediates Insulin Inhibition of Bcl2-Modifying Factor Expression and Tubulopathy in Diabetic Kidney

Authors: Ghosh, Anindya, Zhao, Shuiling, Lo, Chao-Sheng, Maachi, Hasna, Chenier, Isabelle, Lateef, Muhammad, Abdo, Shaaban, Filep, Janos, Ingelfinger, Julie, Zhang, Shao-Ling, Chan, John

Source: Scientific reports. 9(1):1-16

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100135419856.0x000001&indx=1&recIds=ETOCvdc_100135419856.0x000001

Tubular Deficiency of Heterogeneous Nuclear Ribonucleoprotein F Elevates Systolic Blood Pressure and Induces Glycosuria in Mice

Authors: Lo, Chao-Sheng, Miyata, Kana, Zhao, Shuiling, Ghosh, Anindya, Chang, Shiao-Ying, Chenier, Isabelle, Filep, Janos, Ingelfinger, Julie, Zhang, Shao-Ling, Chan, John

Source: Scientific reports. 9(1):1-14

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100190886366.0x000001&indx=1&recIds=ETOCvdc_100190886366.0x000001

Hedgehog Interacting Protein (Hhip) Regulates Insulin Secretion in Mice Fed High Fat Diets

Authors: Nchienzia, Henry, Liao, Min-Chun, Zhao, Xin-Ping, Chang, Shiao-Ying, Lo, Chao-Sheng, Chenier, Isabelle, Ingelfinger, Julie, Chan, John, Zhang, Shao-Ling

Source: Scientific reports. 9(1):1-12

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100185667455.0x000001&indx=1&recIds=ETOCvdc_100185667455.0x000001

Hedgehog Interacting Protein Promotes Fibrosis and Apoptosis in Glomerular Endothelial Cells in Murine Diabetes

Authors: Zhao, Xin-Ping, Chang, Shiao-Ying, Liao, Min-Chun, Lo, Chao-Sheng, Chenier, Isabelle, Luo, Hongyu, Chiasson, Jean-Louis, Ingelfinger, Julie, Chan, John, Zhang, Shao-Ling

Source: Scientific reports. 8(1):1-10

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100132427031.0x000001&indx=1&recIds=ETOCvdc_100132427031.0x000001

NRF2 Deficiency Attenuates Diabetic Kidney Disease in Db/Db Mice via Down-Regulation of Angiotensinogen, SGLT2, CD36, and FABP4 Expression and Lipid Accumulation in Renal Proximal Tubular Cells.

Authors: Su, Ke, Zhao, Shui-Ling, Yang, Wen-Xia, Lo, Chao-Sheng, Chenier, Isabelle, Liao, Min-Chun, Pang, Yu-Chao, Peng, Jun-Zheng, Miyata, Kana N., Cailhier, Jean-Francois, Ethier, Jean, Lattouf, Jean-Baptiste, Filep, Janos G., Ingelfinger, Julie R., Zhang, Shao-Ling, Chan, John S. D.

Source: Antioxidants; Sep2023, Vol. 12 Issue 9, p1715, 20p

Subject Terms: NUCLEAR factor E2 related factor, DIABETIC nephropathies, ANGIOTENSINOGEN, SODIUM-glucose cotransporters

WCN24-2550 HETEROGENEOUS NUCLEAR RIBONUCLEOPROTEIN F DEFICIENCY IN MOUSE PODOCYTE PROMOTES PODOCYTOPATHY MEDIATED BY METHYLTRANSFERASE-LIKE 14 NUCLEAR TRANSLOCATION RESULTING IN SIRTUIN-1 GENE INHIBITION

Authors: Zhang, Shao-Ling ¹, Liao, Min-Chun ², Lo, Chao-Sheng ², Pang, Yu-Chao ², Yang, Weng-Xia ², Su, Ke ², Zhao, Xin-Ping ², Miyata, Kana Noshiro ³, Peng, Junzheng ², Ingelfinger, Julie R. ⁴, Chan, John S.D. ²

Source: In Kidney International Reports April 2024 9(4) Supplement:S329-S330

Cholesteryl ester transfer protein B1B1 genotype as a predictor of coronary artery disease in Taiwanese with type 2 diabetes mellitus

Authors: Hsieh, Ming-Chia, Tien, Kai-Jen, Chang, Shun-Jen, Lo, Chao-Sheng, Hsin, Shih-Chieh, Hsiao, Jeng-Yueh, Hsu, Shih-Chieh, Liang, Hui-Ting, Chen, Hung-Chun, Shin, Shyi-Jang, Lin, Shiu-Ru

Source: In Metabolism 2007 56(6):745-750

Deletion of heterogeneous nuclear ribonucleoprotein F in renal tubules downregulates SGLT2 expression and attenuates hyperfiltration and kidney injury in a mouse model of diabetes.

Authors: Miyata, Kana N., Lo, Chao-Sheng, Zhao, Shuiling, Zhao, Xin-Ping, Chenier, Isabelle, Yamashita, Michifumi, Filep, Janos G., Ingelfinger, Julie R., Zhang, Shao-Ling, Chan, John S. D.

Source: Diabetologia; Nov2021, Vol. 64 Issue 11, p2589-2601, 13p

Overexpression of Nrf2 in Renal Proximal Tubular Cells Stimulates Sodium-Glucose Cotransporter 2 Expression and Exacerbates Dysglycemia and Kidney Injury in Diabetic Mice.

Authors: Zhao, Shuiling¹ (AUTHOR), Lo, Chao-Sheng¹ (AUTHOR), Miyata, Kana N.¹ (AUTHOR), Ghosh, Anindya¹ (AUTHOR), Zhao, Xin-Ping¹ (AUTHOR), Chenier, Isabelle¹ (AUTHOR), Cailhier, Jean-Francois¹ (AUTHOR), Ethier, Jean¹ (AUTHOR), Lattouf, Jean-Baptiste¹ (AUTHOR), Filep, Janos G.² (AUTHOR), Ingelfinger, Julie R.³ (AUTHOR), Zhang, Shao-Ling¹ (AUTHOR) john.chan@umontreal.ca, Chan, John S.D.¹ (AUTHOR) shao.ling.zhang@umontreal.ca, Miyata, Kana⁴ (AUTHOR), Zhao, Xinping⁴ (AUTHOR)

Source: Diabetes. Jun2021, Vol. 70 Issue 6, p1388-1403. 16p.

Subject Terms: *KIDNEY injuries, *BLOOD sugar, *GLOMERULAR filtration rate, *MICE, *COMPLEMENTARY DNA, *DIABETES complications, *PROTEINS, *BIOCHEMISTRY, *DISEASE progression, *RESEARCH, *HYPERGLYCEMIA, *CELL culture, *ANIMAL experimentation, *RESEARCH methodology, *DIABETES, *KIDNEY tubules, *MEDICAL cooperation, *EVALUATION research, *PHENOMENOLOGY, *COMPARATIVE studies, *RESEARCH funding, *DIABETIC nephropathies

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AT2R deficiency mediated podocyte loss via activation of ectopic hedgehog interacting protein ( Hhip) gene expression.

Authors: Liao, Min‐Chun, Zhao, Xin‐Ping, Chang, Shiao‐Ying, Lo, Chao‐Sheng, Chenier, Isabelle, Takano, Tomoko, Ingelfinger, Julie R, Zhang, Shao‐Ling

Source: Journal of Pathology; Nov2017, Vol. 243 Issue 3, p279-293, 15p