mTORC1 restricts TFE3 activity by auto-regulating its presence on lysosomes

Authors: Zwakenberg, Susan, Westland, Denise, van Es, Robert M., Rehmann, Holger, Anink, Jasper, Ciapaite, Jolita, Bosma, Marjolein, Stelloo, Ellen, Liv, Nalan, Sobrevals Alcaraz, Paula, Verhoeven-Duif, Nanda M., Jans, Judith J.M., Vos, Harmjan R., Aronica, Eleonora, Zwartkruis, Fried J.T.

Source: In Molecular Cell 21 November 2024 84(22):4368-4384

Impaired LAIR-1-mediated immune control due to collagen degradation in fibrosis

Authors: Carvalheiro, Tiago, Marut, Wioleta, Pascoal Ramos, M. Inês, García, Samuel, Fleury, Devan, Affandi, Alsya J., Meijers, Aniek S., Giovannone, Barbara, Tieland, Ralph G., Elshof, Eline, Ottria, Andrea, Cossu, Marta, Meizlish, Matthew L., Veenendaal, Tineke, Ramanujam, Meera, Moreno-García, Miguel E., Klumperman, Judith, Liv, Nalan, Radstake, Timothy R.D.J., Meyaard, Linde

Source: In Journal of Autoimmunity June 2024 146

The potential and limitations of intrahepatic cholangiocyte organoids to study inborn errors of metabolism

Authors: Lehmann, Vivian, Schene, Imre F., Ardisasmita, Arif I., Liv, Nalan, Veenendaal, Tineke, Klumperman, Judith, Doef, Hubert P. J., Verkade, Henkjan J., Verstegen, Monique M. A., Laan, Luc J. W., Jans, Judith J. M., Verhoeven‐Duif, Nanda M., Hasselt, Peter M., Nieuwenhuis, Edward E. S., Spee, Bart, Fuchs, Sabine A.

Source: Journal of inherited metabolic disease. 45(2):353-365

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Bimodal endocytic probe for three-dimensional correlative light and electron microscopy

Authors: Fermie, Job, de Jager, Leanne, Foster, Helen E., Veenendaal, Tineke, de Heus, Cecilia, van Dijk, Suzanne, ten Brink, Corlinda, Oorschot, Viola, Yang, Lin, Li, Wei, Müller, Wally H., Howes, Stuart, Carter, Andrew P., Förster, Friedrich, Posthuma, George, Gerritsen, Hans C., Klumperman, Judith, Liv, Nalan

Source: In Cell Reports Methods 23 May 2022 2(5)

FER regulates endosomal recycling and is a predictor for adjuvant taxane benefit in breast cancer

Authors: Tavares, Sandra, Liv, Nalan, Pasolli, Milena, Opdam, Mark, Rätze, Max A.K., Saornil, Manuel, Sluimer, Lilian M., Hengeveld, Rutger C.C., van Es, Robert, van Werkhoven, Erik, Vos, Harmjan, Rehmann, Holger, Burgering, Boudewijn M.T., Oosterkamp, Hendrika M., Lens, Susanne M.A., Klumperman, Judith, Linn, Sabine C., Derksen, Patrick W.B.

Source: In Cell Reports 5 April 2022 39(1)

Organoid-based drug screening reveals neddylation as therapeutic target for malignant rhabdoid tumors

Authors: Calandrini, Camilla, van Hooff, Sander R., Paassen, Irene, Ayyildiz, Dilara, Derakhshan, Sepide, Dolman, M. Emmy M., Langenberg, Karin P.S., van de Ven, Marieke, de Heus, Cecilia, Liv, Nalan, Kool, Marcel, de Krijger, Ronald R., Tytgat, Godelieve A.M., van den Heuvel-Eibrink, Marry M., Molenaar, Jan J., Drost, Jarno

Source: In Cell Reports 24 August 2021 36(8)

Optimization of negative stage bias potential for faster imaging in large-scale electron microscopy

Authors: Lane, Ryan, Vos, Yoram, Wolters, Anouk H.G., Kessel, Luc van, Chen, S. Elisa, Liv, Nalan, Klumperman, Judith, Giepmans, Ben N.G., Hoogenboom, Jacob P.

Source: In Journal of Structural Biology: X 2021 5

Integrated super resolution fluorescence microscopy and transmission electron microscopy

Authors: Mohammadian, Sajjad, Agronskaia, Alexandra V, Blab, Gerhard A, van Donselaar, Elly G, de Heus, Cecilia, Liv, Nalan, Klumperman, Judith, Gerritsen, Hans C

Source: In Ultramicroscopy August 2020 215

Post‐Transcriptional Regulation of Rab7a in Lysosomal Positioning and Drug Resistance in Nutrient‐Limited Cancer Cells.

Authors: Güleç Taşkıran, Aliye Ezgi, Hüsnügil, Hepşen H., Soltani, Zahra E., Oral, Göksu, Menemenli, Nazlı S., Hampel, Chuanpit, Huebner, Kerstin, Erlenbach‐Wuensch, Katharina, Sheraj, Ilir, Schneider‐Stock, Regine, Akyol, Aytekin, Liv, Nalan, Banerjee, Sreeparna

Source: Traffic; Sep2024, Vol. 25 Issue 9, p1-18, 18p

Subject Terms: DRUG resistance in cancer cells, CELL populations, CHORIOALLANTOIS, CELL survival, DRUG resistance

High accuracy, fiducial marker-based image registration of correlative microscopy images

Authors: Mohammadian, Sajjad, Fokkema, Jantina, Agronskaia, Alexandra, Liv, Nalan, Heus, Cecilia, Donselaar, Elly, Blab, Gerhard, Klumperman, Judith, Gerritsen, Hans

Source: Scientific reports. 9(1):1-10

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FAST-EM array tomography: a workflow for multibeam volume electron microscopy

Authors: Kievits, Arent J., Duinkerken, B. H. Peter, Lane, Ryan, de Heus, Cecilia, van Beijeren Bergen en Henegouwen, Daan, Höppener, Tibbe, Wolters, Anouk H. G., Liv, Nalan, Giepmans, Ben N. G., Hoogenboom, Jacob P.

Source: Methods in Microscopy; July 2024, Vol. 1 Issue: 1 p49-64, 16p

Fluorescently Labelled Silica Coated Gold Nanoparticles as Fiducial Markers for Correlative Light and Electron Microscopy

Authors: Fokkema, Jantina, Fermie, Job, Liv, Nalan, Heuvel, Dave, Konings, Tom, Blab, Gerhard, Meijerink, Andries, Klumperman, Judith, Gerritsen, Hans

Source: Scientific reports. 8(1):1-10

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Neurodegenerative VPS41 variants inhibit HOPS function and mTORC1‐dependent TFEB/TFE3 regulation

Authors: van der Welle, Reini E N, Jobling, Rebekah, Burns, Christian, Sanza, Paolo, van der Beek, Jan A, Fasano, Alfonso, Chen, Lan, Zwartkruis, Fried J, Zwakenberg, Susan, Griffin, Edward F, ten Brink, Corlinda, Veenendaal, Tineke, Liv, Nalan, van Ravenswaaij‐Arts, Conny M A, Lemmink, Henny H, Pfundt, Rolph, Blaser, Susan, Sepulveda, Carolina, Lozano, Andres M, Yoon, Grace, Santiago‐Sim, Teresa, Asensio, Cedric S, Caldwell, Guy A, Caldwell, Kim A, Chitayat, David, Klumperman, Judith

Source: EMBO molecular medicine. 13(5)

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An Organoid for Woven Bone

Authors: Akiva, Anat, Melke, Johanna, Ansari, Sana, Liv, Nalan, Meijden, Robin, Erp, Merijn, Zhao, Feihu, Stout, Merula, Nijhuis, Wouter H., Heus, Cilia, Muñiz Ortera, Claudia, Fermie, Job, Klumperman, Judith, Ito, Keita, Sommerdijk, Nico, Hofmann, Sandra

Source: Advanced functional materials. 31(17)

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EB1 and EB3 regulate microtubule minus end organization and Golgi morphology

Authors: Yang, Chao, Wu, Jingchao, de Heus, Cecilia, Grigoriev, Ilya, Liv, Nalan, Yao, Yao, Smal, Ihor, Meijering, Erik, Klumperman, Judith, Qi, Robert Z.

Source: Journal of cell biology. 216(10):3179-3198

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RUFY1 binds Arl8b and mediates endosome-to-TGN CI-M6PR retrieval for cargo sorting to lysosomes

Authors: Rawat, Shalini, Chatterjee, Dhruba, Marwaha, Rituraj, Charak, Gitanjali, Kumar, Gaurav, Shaw, Shrestha, Khatter, Divya, Sharma, Sheetal, de Heus, Cecilia, Liv, Nalan

Source: Journal of cell biology. 222(1):e202108001-e202108001

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Scanning electron microscopy of individual nanoparticle bio-markers in liquid

Authors: Liv, Nalan, Lazić, Ivan, Kruit, Pieter, Hoogenboom, Jacob P.

Source: In Ultramicroscopy August 2014 143:93-99

Loss of SMAD4 Alters BMP Signaling to Promote Colorectal Cancer Cell Metastasis via Activation of Rho and ROCK

Authors: Voorneveld, Philip W., Kodach, Liudmila L., Jacobs, Rutger J., Liv, Nalan, Zonnevylle, A. Christiaan, Hoogenboom, Jacob P., Biemond, Izak, Verspaget, Hein W., Hommes, Daniel W., de Rooij, Karien, van Noesel, Carel J.M., Morreau, Hans, van Wezel, Tom, Offerhaus, G. Johan A., van den Brink, Gijs R., Peppelenbosch, Maikel P., ten Dijke, Peter, Hardwick, James C.H.

Source: In Gastroenterology July 2014 147(1):196-208

Integrated optical and charged particle inspection apparatus

Chapter 12 - Functional characterization of endo-lysosomal compartments by correlative live-cell and volume electron microscopy

Authors: Liv, Nalan ^*, Fermie, Job, ten Brink, Corlinda B.M., de Heus, Cecilia, Klumperman, Judith

Source: In Methods in Cell Biology 2023 177:301-326