Histamine H4 receptor antagonists for the treatment of inflammatory disorders

Authors: Liu, Wai L.

Source: In Drug Discovery Today August 2014 19(8):1222-1225

Preclinical Evaluation of an Inhibitor of Cytosolic Phospholipase A2α for the Treatment of Asthma

Authors: Hewson, Christopher A. ^*, Patel, Sheena, Calzetta, Luigino, Campwala, Hinnah, Havard, Suzanne, Luscombe, Emma, Clarke, Philip A., Peachell, Peter T., Matera, Maria G., Cazzola, Mario, Page, Clive, Abraham, William M., Williams, Cara M., Clark, James D., Liu, Wai L., Clarke, Nicholas P., Yeadon, Michael

Source: In The Journal of Pharmacology and Experimental Therapeutics March 2012 340(3):656-665

Challenges of drug discovery in novel target space. The discovery and evaluation of PF-3893787: A novel histamine H4 receptor antagonist

Authors: Mowbray, Charles E., Bell, Andrew S., Clarke, Nicholas P., Collins, Michelle, Jones, Rhys M., Lane, Charlotte A.L., Liu, Wai L., Newman, Sandra D., Paradowski, Michael, Schenck, Emanuel J., Selby, Mathew D., Swain, Nigel A., Williams, David H.

Source: In Bioorganic & Medicinal Chemistry Letters 2011 21(21):6596-6602

Discovery of a series of potent and selective human H4 antagonists using ligand efficiency and libraries to explore structure–activity relationship (SAR)

Authors: Masood, M. Abid, Selby, Matthew D., Bell, Andrew S., Mansfield, Andrew C., Gardner, Mark, Smith, Graham F., Lane, Charlotte, Kenyon-Edwards, Helen, Osborne, Rachel, Jones, Rhys M., Liu, Wai L., Brown, Christopher D., Clarke, Nicholas, Perrucio, Francesca, Mowbray, Charles E.

Source: In Bioorganic & Medicinal Chemistry Letters 2011 21(21):6591-6595

This result is not displayed to guests.
Login for full access.

This result is not displayed to guests.
Login for full access.

This result is not displayed to guests.
Login for full access.

Gene Expression and Immunolocalization of 15-Lipoxygenase Isozymes in the Airway Mucosa of Smokers with Chronic Bronchitis.

Authors: Jie Zhu, Kilty, Iain, Granger, Helen, Gamble, Elizabeth, Yu Sheng Qiu, Hattotuwa, Keith, Elston, Will, Liu, Wai L., Oliva, Alessandro, Pauwels, Romain A., Kips, Johan C., De Rose, Virginia, Barnes, Neil, Yeadon, Michael, Jenkinson, Stephen, Jeffery, Peter K.

Source: American Journal of Respiratory Cell & Molecular Biology; 2002, Vol. 27 Issue 6, p666-677, 12p, 7 Color Photographs, 3 Charts, 4 Graphs

CNS-Sparing Histamine H 3 Receptor Antagonist as a Candidate to Prevent the Diabetes-Associated Gastrointestinal Symptoms.

Authors: Rosa, Arianna Carolina, Nardini, Patrizia, Sgambellone, Silvia, Gurrieri, Maura, Spampinato, Simona Federica, Dell'Accio, Alfonso, Chazot, Paul L, Obara, Ilona, Liu, Wai L, Pini, Alessandro

Source: Biomolecules (2218-273X); Feb2022, Vol. 12 Issue 2, p184, 1p

Subject Terms: HISTAMINE receptors, HISTAMINE, ANTIHISTAMINES, GLYCEMIC control, AUTONOMIC nervous system, ETIOLOGY of diabetes, SYMPTOMS, SUBMUCOUS plexus