Ketogenic diet suppresses colorectal cancer through the gut microbiome long chain fatty acid stearate

Authors: Mina Tsenkova, Madita Brauer, Vitaly Igorevich Pozdeev, Marat Kasakin, Susheel Bhanu Busi, Maryse Schmoetten, Dean Cheung, Marianne Meyers, Fabien Rodriguez, Anthoula Gaigneaux, Eric Koncina, Cedric Gilson, Lisa Schlicker, Diran Herebian, Martine Schmitz, Laura de Nies, Ertan Mayatepek, Serge Haan, Carine de Beaufort, Thorsten Cramer, Johannes Meiser, Carole L. Linster, Paul Wilmes, Elisabeth Letellier

Source: Nature Communications, Vol 16, Iss 1, Pp 1-16 (2025)

Subject Terms: Science

File Description: electronic resource

Relation: https://doaj.org/toc/2041-1723

Access URL: https://doaj.org/article/d490addab34f41b4a092ad601a814f68

A multidimensional atlas of human glioblastoma-like organoids reveals highly coordinated molecular networks and effective drugs

Authors: Changwen Wang, Meng Sun, Chunxuan Shao, Lisa Schlicker, Yue Zhuo, Yassin Harim, Tianping Peng, Weili Tian, Nadja Stöffler, Martin Schneider, Dominic Helm, Youjun Chu, Beibei Fu, Xiaoliang Jin, Jan-Philipp Mallm, Moritz Mall, Yonghe Wu, Almut Schulze, Hai-Kun Liu

Source: npj Precision Oncology, Vol 8, Iss 1, Pp 1-21 (2024)

Subject Terms: Neoplasms. Tumors. Oncology. Including cancer and carcinogens, RC254-282

File Description: electronic resource

Relation: https://doaj.org/toc/2397-768X

Access URL: https://doaj.org/article/d63afc60087d40eba8fc806d9ff1af6b

LRP8‐mediated selenocysteine uptake is a targetable vulnerability in MYCN‐amplified neuroblastoma

Authors: Hamed Alborzinia, Zhiyi Chen, Umut Yildiz, Florencio Porto Freitas, Felix C E Vogel, Julianna Patricia Varga, Jasmin Batani, Christoph Bartenhagen, Werner Schmitz, Gabriele Büchel, Bernhard Michalke, Jashuo Zheng, Svenja Meierjohann, Enrico Girardi, Elisa Espinet, Andrés F Flórez, Ancely Ferreira dos Santos, Nesrine Aroua, Tasneem Cheytan, Julie Haenlin, Lisa Schlicker, Thamara N Xavier da Silva, Adriana Przybylla, Petra Zeisberger, Giulio Superti‐Furga, Martin Eilers, Marcus Conrad, Marietta Fabiano, Ulrich Schweizer, Matthias Fischer, Almut Schulze, Andreas Trumpp, José Pedro Friedmann Angeli

Source: EMBO Molecular Medicine, Vol 15, Iss 8, Pp 1-17 (2023)

Subject Terms: ferroptosis, neuroblastoma, selenocysteine, selenoprotein, synthetic lethality, Medicine (General), R5-920, Genetics, QH426-470

File Description: electronic resource

Relation: https://doaj.org/toc/1757-4676; https://doaj.org/toc/1757-4684

Access URL: https://doaj.org/article/f738f088a5b24d4d84df76ffa09916f9

Formate promotes invasion and metastasis in reliance on lipid metabolism

Authors: Catherine Delbrouck, Nicole Kiweler, Oleg Chen, Vitaly I. Pozdeev, Lara Haase, Laura Neises, Anaïs Oudin, Aymeric Fouquier d’Hérouël, Ruolin Shen, Lisa Schlicker, Rashi Halder, Antoine Lesur, Anne Schuster, Nadja I. Lorenz, Christian Jaeger, Maureen Feucherolles, Gilles Frache, Martyna Szpakowska, Andy Chevigne, Michael W. Ronellenfitsch, Etienne Moussay, Marie Piraud, Alexander Skupin, Almut Schulze, Simone P. Niclou, Elisabeth Letellier, Johannes Meiser

Source: Cell Reports, Vol 42, Iss 9, Pp 113034- (2023)

Subject Terms: CP: Cancer, CP: Metabolism, Biology (General), QH301-705.5

File Description: electronic resource

Relation: http://www.sciencedirect.com/science/article/pii/S2211124723010458; https://doaj.org/toc/2211-1247

Access URL: https://doaj.org/article/d667e6854d774c98bcdedc3d5a151980

c-Myc plays a key role in IFN-γ-induced persistence of Chlamydia trachomatis

Authors: Nadine Vollmuth, Lisa Schlicker, Yongxia Guo, Pargev Hovhannisyan, Sudha Janaki-Raman, Naziia Kurmasheva, Werner Schmitz, Almut Schulze, Kathrin Stelzner, Karthika Rajeeve, Thomas Rudel

Source: eLife, Vol 11 (2022)

Subject Terms: Chlamydia trachomatis, persistence, c-Myc, interferon-gamma, Medicine, Science, Biology (General), QH301-705.5

File Description: electronic resource

Relation: https://elifesciences.org/articles/76721; https://doaj.org/toc/2050-084X

Access URL: https://doaj.org/article/b5901aba18994e7e8ed2c8f6ada5ed36

Systemic Lactate Acts as a Metabolic Buffer in Humans and Prevents Nutrient Overflow in the Postprandial Phase

Authors: Lisa Schlicker, Gang Zhao, Christian-Alexander Dudek, Hanny M. Boers, Michael Meyer-Hermann, Doris M. Jacobs, Karsten Hiller

Source: Frontiers in Nutrition, Vol 9 (2022)

Subject Terms: metabolic flux, glucose, wheat, stable isotope labeling, metabolic modeling, lactate, Nutrition. Foods and food supply, TX341-641

File Description: electronic resource

Relation: https://www.frontiersin.org/articles/10.3389/fnut.2022.785999/full; https://doaj.org/toc/2296-861X

Access URL: https://doaj.org/article/b6c629a3212640379415a8c6e083d9da

Plasma Metabolome Signature Indicative of BRCA1 Germline Status Independent of Cancer Incidence

Authors: Judith Penkert, Andre Märtens, Martin Seifert, Bernd Auber, Katja Derlin, Ursula Hille-Betz, Philipp Hörmann, Norman Klopp, Jana Prokein, Lisa Schlicker, Frank Wacker, Hannah Wallaschek, Brigitte Schlegelberger, Karsten Hiller, Tim Ripperger, Thomas Illig

Source: Frontiers in Oncology, Vol 11 (2021)

Subject Terms: breast cancer, plasma metabolome, BRCA1 germline mutation, energy metabolism, NAD+ balance, HIF1 alpha, Neoplasms. Tumors. Oncology. Including cancer and carcinogens, RC254-282

File Description: electronic resource

Relation: https://www.frontiersin.org/articles/10.3389/fonc.2021.627217/full; https://doaj.org/toc/2234-943X

Access URL: https://doaj.org/article/9309d18b7a0b491289529b4fa3c4cfa3

Postprandial Metabolic Effects of Fiber Mixes Revealed by in vivo Stable Isotope Labeling in Humans

Authors: Lisa Schlicker, Hanny M. Boers, Christian-Alexander Dudek, Gang Zhao, Arnab Barua, Jean-Pierre Trezzi, Michael Meyer-Hermann, Doris M. Jacobs, Karsten Hiller

Source: Metabolites, Vol 9, Iss 5, p 91 (2019)

Subject Terms: 13C-enrichment, GC-MS, wheat flour, guar gum, chickpea flour, metabolism, starch, Microbiology, QR1-502

File Description: electronic resource

Relation: https://www.mdpi.com/2218-1989/9/5/91; https://doaj.org/toc/2218-1989

Access URL: https://doaj.org/article/cad2f40f65cd417e8618644d556a86d9