Spinal delivery of an AAV-vector stably expressing the VDAC1 mitochondrial protein restores cellular respiration in an ALS model mouse

Authors: Magrì, Andrea, Lipari, Cristiana, Battiato, Giuseppe, Caruso, Pietro, Infantino, Iolanda, Nibali, Stefano Conti, Messina, Angela

Source: In BBA - Bioenergetics 1 September 2024 1865 Supplement

Voltage Dependent Anion selective Channel 3 (VDAC3) protects mitochondria from oxidative stress

Authors: Reina, Simona, Nibali, Stefano Conti, Tommasello, Marianna F., Lipari, Cristiana, Infantino, Iolanda, Battiato, Giuseppe, Guarino, Francesca, Magrì, Andrea, Messina, Angela, De Pinto, Vito

Source: Biochimica et biophysica acta. 1863(S)

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100168840161.0x000001&indx=1&recIds=ETOCvdc_100168840161.0x000001

AAV-mediated upregulation of VDAC1 rescues the mitochondrial respiration and sirtuins expression in a SOD1 mouse model of inherited ALS.

Authors: Magrì, Andrea, Lipari, Cristiana Lucia Rita, Caccamo, Antonella, Battiato, Giuseppe, Conti Nibali, Stefano, De Pinto, Vito, Guarino, Francesca, Messina, Angela

Source: Cell Death Discovery; 4/16/2024, Vol. 10 Issue 1, p1-10, 10p

VDAC1 Knockout Affects Mitochondrial Oxygen Consumption Triggering a Rearrangement of ETC by Impacting on Complex I Activity.

Authors: Magrì, Andrea, Cubisino, Salvatore Antonio Maria, Battiato, Giuseppe, Lipari, Cristiana Lucia Rita, Conti Nibali, Stefano, Saab, Miriam Wissam, Pittalà, Alessandra, Amorini, Angela Maria, De Pinto, Vito, Messina, Angela

Source: International Journal of Molecular Sciences; Feb2023, Vol. 24 Issue 4, p3687, 16p

Subject Terms: OXYGEN consumption, MITOCHONDRIA, MITOCHONDRIAL membranes, ELECTRON transport, CELL metabolism, RESPIRATION

α-Synuclein A53T Promotes Mitochondrial Proton Gradient Dissipation and Depletion of the Organelle Respiratory Reserve in a Neuroblastoma Cell Line.

Authors: Risiglione, Pierpaolo, Cubisino, Salvatore Antonio Maria, Lipari, Cristiana Lucia Rita, De Pinto, Vito, Messina, Angela, Magrì, Andrea

Source: Life (2075-1729); Jun2022, Vol. 12 Issue 6, p894, 10p

Subject Terms: ALPHA-synuclein, CELL lines, MITOCHONDRIA, PARKINSON'S disease, NEUROBLASTOMA, MITOCHONDRIAL membranes, ORGANELLES, PLANT mitochondria