Salt‐inducible kinases are required for glucose uptake and insulin signaling in human adipocytes

Authors: Säll, Johanna, Lindahl, Maria, Fritzen, Andreas M., Fryklund, Claes, Kopietz, Franziska, Nyberg, Emma, Warvsten, Anna, Morén, Björn, Foretz, Marc, Kiens, Bente, Stenkula, Karin G., Göransson, Olga

Source: Obesity. 31(10):2515-2529

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100192846742.0x000001&indx=1&recIds=ETOCvdc_100192846742.0x000001

Xylooligosaccharides Increase Bifidobacteria and Lachnospiraceae in Mice on a High-Fat Diet, with a Concomitant Increase in Short-Chain Fatty Acids, Especially Butyric Acid

Authors: Berger, Karin, Burleigh, Stephen, Lindahl, Maria, Bhattacharya, Abhishek, Patil, Prachiti, Stålbrand, Henrik, Karlsson, Eva Nordberg, Hållenius, Frida, Nyman, Margareta, Adlercreutz, Patrick

Source: Journal of agricultural and food chemistry. 69(12):3617-3625

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCRN626372452&indx=1&recIds=ETOCRN626372452

Neuroplastin Modulates Anti-inflammatory Effects of MANF

Authors: Yagi, Takuya, Asada, Rie, Kanekura, Kohsuke, Eesmaa, Ave, Lindahl, Maria, Saarma, Mart, Urano, Fumihiko

Source: In iScience 18 December 2020 23(12)

Discovery of endoplasmic reticulum calcium stabilizers to rescue ER-stressed podocytes in nephrotic syndrome

Authors: Park, Sun-Ji, Kim, Yeawon, Yang, Shyh-Ming, Henderson, Mark J., Yang, Wei, Lindahl, Maria, Urano, Fumihiko, Chen, Ying Maggie

Source: Proceedings of the National Academy of Sciences of the United States of America, 2019 Jul 01. 116(28), 14154-14163.

Access URL: https://www.jstor.org/stable/26760999

Cerebral dopamine neurotrophic factor–deficiency leads to degeneration of enteric neurons and altered brain dopamine neuronal function in mice

Authors: Lindahl, Maria, Chalazonitis, Alcmène, Palm, Erik, Pakarinen, Emmi, Danilova, Tatiana, Pham, Tuan D., Setlik, Wanda, Rao, Meenakshi, Võikar, Vootele, Huotari, Jatta, Kopra, Jaakko, Andressoo, Jaan-Olle, Piepponen, Petteri T., Airavaara, Mikko, Panhelainen, Anne, Gershon, Michael D., Saarma, Mart

Source: In Neurobiology of Disease February 2020 134

Cerebral dopamine neurotrophic factor is essential for enteric neuronal development, maintenance, and regulation of gastrointestinal transit

Authors: Chalazonitis, Alcmène, Li, ZhiShan, Pham, Tuan D., Chen, Jason, Rao, Meenakshi, Lindholm, Päivi, Saarma, Mart, Lindahl, Maria, Gershon, Michael D.

Source: Journal of comparative neurology. 528(14):2420-2444

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100108109811.0x000001&indx=1&recIds=ETOCvdc_100108109811.0x000001

Stereocilia fusion pathology in the cochlear outer hair cells at the nanoscale level.

Authors: Ikäheimo, Kuu, Leinonen, Saija, Lankinen, Tuuli, Lindahl, Maria, Saarma, Mart, Pirvola, Ulla

Source: Journal of Physiology; Aug2024, Vol. 602 Issue 16, p3995-4025, 31p

Subject Terms: HAIR cells, MECHANOTRANSDUCTION (Cytology), DEAFNESS, LABORATORY mice, ENDOPLASMIC reticulum

Gfra1 Underexpression Causes Hirschsprung’s Disease and Associated Enterocolitis in Mice

Authors: Porokuokka, L. Lauriina, Virtanen, Heikki T., Lindén, Jere, Sidorova, Yulia, Danilova, Tatiana, Lindahl, Maria, Saarma, Mart, Andressoo, Jaan-Olle

Source: In Cellular and Molecular Gastroenterology and Hepatology 2019 7(3):655-678

MANF Promotes Differentiation and Migration of Neural Progenitor Cells with Potential Neural Regenerative Effects in Stroke

Authors: Tseng, Kuan-Yin, Anttila, Jenni E., Khodosevich, Konstantin, Tuominen, Raimo K., Lindahl, Maria, Domanskyi, Andrii, Airavaara, Mikko

Source: In Molecular Therapy 3 January 2018 26(1):238-255

Pancreatic β-cell protection from inflammatory stress by the endoplasmic reticulum proteins thrombospondin 1 and mesencephalic astrocyte-derived neutrotrophic factor (MANF)

Authors: Cunha, Daniel A., Cito, Monia, Grieco, Fabio Arturo, Cosentino, Cristina, Danilova, Tatiana, Ladrière, Laurence, Lindahl, Maria, Domanskyi, Andrii, Bugliani, Marco, Marchetti, Piero, Eizirik, Décio L., Cnop, Miriam

Source: In Journal of Biological Chemistry 8 September 2017 292(36):14977-14988

Regulation of Cell Fate Decision of Undifferentiated Spermatogonia by GDNF

Authors: Meng, Xiaojuan, Lindahl, Maria, Hyvönen, Mervi E., Parvinen, Martti, de Rooij, Dirk G., Hess, Michael W., Raatikainen-Ahokas, Anne, Sainio, Kirsi, Rauvala, Heikki, Lakso, Merja, Pichel, José G., Westphal, Heiner, Saarma, Mart, Sariola, Hannu

Source: Science, 2000 Feb . 287(5457), 1489-1493.

Access URL: https://www.jstor.org/stable/3074551

Unconventional neurotrophic factors CDNF and MANF: Structure, physiological functions and therapeutic potential

Authors: Lindahl, Maria, Saarma, Mart, Lindholm, Päivi

Source: In Neurobiology of Disease January 2017 97 Part B:90-102

MANF protects human pancreatic beta cells against stress-induced cell death

Authors: Hakonen, Elina, Chandra, Vikash, Fogarty, Christopher L., Yu, Nancy Yiu-Lin, Ustinov, Jarkko, Katayama, Shintaro, Galli, Emilia, Danilova, Tatiana, Lindholm, Päivi, Vartiainen, Aki, Einarsdottir, Elisabet, Krjutškov, Kaarel, Kere, Juha, Saarma, Mart, Lindahl, Maria, Otonkoski, Timo

Source: Diabetologia. 61(10):2202-2214

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100125287171.0x000001&indx=1&recIds=ETOCvdc_100125287171.0x000001

MANF protein expression is upregulated in immune cells in the ischemic human brain and systemic recombinant MANF delivery in rat ischemic stroke model demonstrates anti-inflammatory effects.

Authors: Anttila, Jenni E., Mattila, Olli S., Liew, Hock-Kean, Mätlik, Kert, Mervaala, Eero, Lindholm, Päivi, Lindahl, Maria, Lindsberg, Perttu J., Tseng, Kuan-Yin, Airavaara, Mikko

Source: Acta Neuropathologica Communications; 1/16/2024, Vol. 12 Issue 1, p1-24, 24p

Subject Terms: ISCHEMIC stroke, PROTEIN expression, NEURAL stem cells, CEREBRAL arteries, GENE expression, CEREBRAL ischemia, RATS

ApoA-I Milano stimulates lipolysis in adipose cells independently of cAMP/PKA activation

Authors: Lindahl, Maria ^{*, †}, Petrlova, Jitka ^*, Dalla-Riva, Jonathan ^*, Wasserstrom, Sebastian ^†, Rippe, Catarina ^§, Domingo-Espin, Joan ^*, Kotowska, Dorota ^†, Krupinska, Ewa ^*, Berggreen, Christine ^**, Jones, Helena A. ^††, Swärd, Karl ^§, Lagerstedt, Jens O. ^*, Göransson, Olga ^**, Stenkula, Karin G. ^†

Source: In Journal of Lipid Research December 2015 56(12):2248-2259

MANF stimulates autophagy and restores mitochondrial homeostasis to treat autosomal dominant tubulointerstitial kidney disease in mice.

Authors: Kim, Yeawon, Li, Chuang, Gu, Chenjian, Fang, Yili, Tycksen, Eric, Puri, Anuradhika, Pietka, Terri A., Sivapackiam, Jothilingam, Kidd, Kendrah, Park, Sun-Ji, Johnson, Bryce G., Kmoch, Stanislav, Duffield, Jeremy S., Bleyer, Anthony J., Jackrel, Meredith E., Urano, Fumihiko, Sharma, Vijay, Lindahl, Maria, Chen, Ying Maggie

Source: Nature Communications; 10/14/2023, Vol. 14 Issue 1, p1-22, 22p

Subject Terms: KIDNEY diseases, AUTOPHAGY, RENAL fibrosis, MITOCHONDRIA, KIDNEY physiology, HOMEOSTASIS

Deficiency of the ER-stress-regulator MANF triggers progressive outer hair cell death and hearing loss

Authors: Herranen, Anni, Ikäheimo, Kuu, Lankinen, Tuuli, Pakarinen, Emmi, Fritzsch, Bernd, Saarma, Mart, Lindahl, Maria, Pirvola, Ulla

Source: Cell death and disease. 11(2)

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100161846881.0x000001&indx=1&recIds=ETOCvdc_100161846881.0x000001

MANF Is Indispensable for the Proliferation and Survival of Pancreatic β Cells

Authors: Lindahl, Maria, Danilova, Tatiana, Palm, Erik, Lindholm, Päivi, Võikar, Vootele, Hakonen, Elina, Ustinov, Jarkko, Andressoo, Jaan-Olle, Harvey, Brandon K., Otonkoski, Timo, Rossi, Jari, Saarma, Mart

Source: Cell reports. 7(2):366-375

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100076778487.0x000001&indx=1&recIds=ETOCvdc_100076778487.0x000001

Persephin signaling through GFRα1: The potential for the treatment of Parkinson's disease

Authors: Sidorova, Yulia A., Mätlik, Kert, Paveliev, Mikhail, Lindahl, Maria, Piranen, Elisa, Milbrandt, Jeffrey, Arumäe, Urmas, Saarma, Mart, Bespalov, Maxim M.

Source: In Molecular and Cellular Neuroscience July 2010 44(3):223-232

NEUROTROPHIC FACTOR MANF AND USES THEREOF