Excessive Accumulation of Ca2 + in Mitochondria of Y522S-RYR1 Knock-in Mice: A Link Between Leak From the Sarcoplasmic Reticulum and Altered Redox State

Authors: Marta Canato, Paola Capitanio, Lina Cancellara, Luigi Leanza, Anna Raffaello, Denis Vecellio Reane, Lorenzo Marcucci, Antonio Michelucci, Feliciano Protasi, Carlo Reggiani

Source: Frontiers in Physiology, Vol 10 (2019)

Subject Terms: excitation–contraction coupling, mitochondria, reactive oxygen species, ryanodine receptor, malignant hyperthermia, Physiology, QP1-981

File Description: electronic resource

Relation: https://www.frontiersin.org/article/10.3389/fphys.2019.01142/full; https://doaj.org/toc/1664-042X

Access URL: https://doaj.org/article/95fb6d4c1e4747f793e73027fb9100f5