Vascular Collagen Type-IV in Hypertension and Cerebral Small Vessel Disease

Authors: Kumar, Apoorva A., Yeo, Natalie, Whittaker, Max, Attra, Priya, Barrick, Thomas R., Bridges, Leslie R., Dickson, Dennis W., Esiri, Margaret M., Farris, Chad W., Graham, Delyth, Lin, Wen Lang, Meijles, Daniel N., Pereira, Anthony C., Perry, Gregory, Rosene, Douglas L., Shtaya, Anan B., Van Agtmael, Tom, Zamboni, Giovanna, Hainsworth, Atticus H.

Source: Stroke. 53(12):3696-3705

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100188617877.0x000001&indx=1&recIds=ETOCvdc_100188617877.0x000001

Mitophagy alterations in Alzheimer's disease are associated with granulovacuolar degeneration and early tau pathology

Authors: Hou, Xu, Watzlawik, Jens O., Cook, Casey, Liu, Chia‐Chen, Kang, Silvia S., Lin, Wen‐Lang, DeTure, Michael, Heckman, Michael G., Diehl, Nancy N., Al‐Shaikh, Fadi S. Hanna, Walton, Ronald L., Ross, Owen A., Melrose, Heather L., Ertekin‐Taner, Nilüfer, Bu, Guojun, Petrucelli, Leonard, Fryer, John D., Murray, Melissa E., Dickson, Dennis W., Fiesel, Fabienne C., Springer, Wolfdieter

Source: Alzheimer's & dementia. 17(3):417-430

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100121639067.0x000001&indx=1&recIds=ETOCvdc_100121639067.0x000001

Heterochromatin anomalies and double-stranded RNA accumulation underlie C9orf72 poly(PR) toxicity

Authors: Zhang, Yong-Jie, Guo, Lin, Gonzales, Patrick K., Gendron, Tania F., Wu, Yanwei, Jansen-West, Karen, O’Raw, Aliesha D., Pickles, Sarah R., Prudencio, Mercedes, Carlomagno, Yari, Gachechiladze, Mariam A., Ludwig, Connor, Tian, Ruilin, Chew, Jeannie, DeTure, Michael, Lin, Wen-Lang, Tong, Jimei, Daughrity, Lillian M., Yue, Mei, Song, Yuping, Andersen, Jonathan W., Castanedes-Casey, Monica, Kurti, Aishe, Datta, Abhishek, Antognetti, Giovanna, McCampbell, Alexander, Rademakers, Rosa, Oskarsson, Björn, Dickson, Dennis W., Kampmann, Martin, Ward, Michael E., Fryer, John D., Link, Christopher D., Shorter, James, Petrucelli, Leonard

Source: Science, 2019 Feb . 363(6428), 707-707.

Access URL: https://www.jstor.org/stable/26611683

Combining P301L and S320F tau variants produces a novel accelerated model of tauopathy

Authors: Koller, Emily J, Gonzalez De La Cruz, Elsa, Machula, Timothy, Ibanez, Kristen R, Lin, Wen-Lang, Williams, Tosha, Riffe, Cara J, Ryu, Daniel, Strang, Kevin H, Liu, Xuefei, Janus, Christopher, Golde, Todd E, Dickson, Dennis, Giasson, Benoit I, Chakrabarty, Paramita

Source: Human molecular genetics. 28(19):3255-3269

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100100510299.0x000001&indx=1&recIds=ETOCvdc_100100510299.0x000001

RAAV-based brain slice culture models of Alzheimer's and Parkinson's disease inclusion pathologies

Authors: Croft, Cara L., Cruz, Pedro E., Ryu, Daniel H., Ceballos-Diaz, Carolina, Strang, Kevin H., Woody, Brittany M., Lin, Wen-Lang, Deture, Michael, Rodríguez-Lebrón, Edgardo, Dickson, Dennis W.

Source: Journal of experimental medicine. 216(3):539-555

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCRN619232134&indx=1&recIds=ETOCRN619232134

Enhanced Neurofibrillary Degeneration in Transgenic Mice Expressing Mutant Tau and APP

Authors: Lewis, Jada, Dickson, Dennis W., Lin, Wen-Lang, Chisholm, Louise, Corral, Anthony, Jones, Graham, Yen, Shu-Hui, Sahara, Naruhiko, Skipper, Lisa, Yager, Debra, Eckman, Chris, Hardy, John, Hutton, Mike, McGowan, Eileen

Source: Science, 2001 Aug . 293(5534), 1487-1491.

Access URL: https://www.jstor.org/stable/3084438

Age- and disease-dependent increase of the mitophagy marker phospho-ubiquitin in normal aging and Lewy body disease

Authors: Hou, Xu, Fiesel, Fabienne C., Truban, Dominika, Castanedes Casey, Monica, Lin, Wen-lang, Soto, Alexandra I., Tacik, Pawel, Rousseau, Linda G., Diehl, Nancy N., Heckman, Michael G., Lorenzo-Betancor, Oswaldo, Ferrer, Isidre, Arbelo, José M., Steele, John C., Farrer, Matthew J., Cornejo-Olivas, Mario, Torres, Luis, Mata, Ignacio F., Graff-Radford, Neill R., Wszolek, Zbigniew K., Ross, Owen A., Murray, Melissa E., Dickson, Dennis W., Springer, Wolfdieter

Source: Autophagy. 14(8):1404-1418

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100067457396.0x000001&indx=1&recIds=ETOCvdc_100067457396.0x000001

ALS/FTD Mutation-Induced Phase Transition of FUS Liquid Droplets and Reversible Hydrogels into Irreversible Hydrogels Impairs RNP Granule Function

Authors: Murakami, Tetsuro, Qamar, Seema, Lin, Julie Qiaojin, Schierle, Gabriele S. Kaminski, Rees, Eric, Miyashita, Akinori, Costa, Ana R., Dodd, Roger B., Chan, Fiona T.S., Michel, Claire H., Kronenberg-Versteeg, Deborah, Li, Yi, Yang, Seung-Pil, Wakutani, Yosuke, Meadows, William, Ferry, Rodylyn Rose, Dong, Liang, Tartaglia, Gian Gaetano, Favrin, Giorgio, Lin, Wen-Lang, Dickson, Dennis W., Zhen, Mei, Ron, David, Schmitt-Ulms, Gerold, Fraser, Paul E., Shneider, Neil A., Holt, Christine, Vendruscolo, Michele, Kaminski, Clemens F., St George-Hyslop, Peter

Source: In Neuron 18 November 2015 88(4):678-690

A Novel Tau Mutation in Exon 12, p.Q336H, Causes Hereditary Pick Disease

Authors: Tacik, Pawel, DeTure, Michael, Hinkle, Kelly M., Lin, Wen-Lang, Sanchez-Contreras, Monica, Carlomagno, Yari, Pedraza, Otto, Rademakers, Rosa, Ross, Owen A., Wszolek, Zbigniew K., Dickson, Dennis W.

Source: Journal of neuropathology and experimental neurology. 74(11):1042-1052

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCETOCvdc_100030242488.0x000001&indx=1&recIds=ETOCETOCvdc_100030242488.0x000001

Age-related decline in white matter integrity in a mouse model of tauopathy: an in vivo diffusion tensor magnetic resonance imaging study

Authors: Sahara, Naruhiko, Perez, Pablo D., Lin, Wen-Lang, Dickson, Dennis W., Ren, Yan, Zeng, Huadong, Lewis, Jada, Febo, Marcelo

Source: In Neurobiology of Aging June 2014 35(6):1364-1374

Vascular Collagen Type-IV in Hypertension and Cerebral Small Vessel Disease.

Authors: Kumar, Apoorva A., Yeo, Natalie, Whittaker, Max, Attra, Priya, Barrick, Thomas R., Bridges, Leslie R., Dickson, Dennis W., Esiri, Margaret M., Farris, Chad W., Graham, Delyth, Lin, Wen Lang, Meijles, Daniel N., Pereira, Anthony C., Perry, Gregory, Rosene, Douglas L., Shtaya, Anan B., Van Agtmael, Tom, Zamboni, Giovanna, Hainsworth, Atticus H.

Source: Stroke (00392499); Dec2023, Vol. 54 Issue 12, p3696-3705, 10p

Aberrant Cleavage of TDP-43 Enhances Aggregation and Cellular Toxicity

Authors: Zhang, Yong-Jie, Xu, Ya-Fei, Cook, Casey, Gendron, Tania F., Roettges, Paul, Link, Christopher D., Lin, Wen-Lang, Tong, Jimei, Castanedes-Casey, Monica, Ash, Peter, Gass, Jennifer, Rangachari, Vijayaraghavan, Buratti, Emanuele, Baralle, Francisco, Golde, Todd E., Dickson, Dennis W., Petrucelli, Leonard, Snyder, Solomon H.

Source: Proceedings of the National Academy of Sciences of the United States of America, 2009 May 01. 106(18), 7607-7612.

Access URL: https://www.jstor.org/stable/40483320

Accelerated Lipofuscinosis and Ubiquitination in Granulin Knockout Mice Suggest a Role for Progranulin in Successful Aging

Authors: Ahmed, Zeshan, Sheng, Hong, Xu, Ya-fei, Lin, Wen-Lang, Innes, Amy E., Gass, Jennifer, Yu, Xin, Hou, Harold, Chiba, Shuichi, Yamanouchi, Keitaro, Leissring, Malcolm, Petrucelli, Leonard, Nishihara, Masugi, Hutton, Michael L., McGowan, Eileen, Dickson, Dennis W., Lewis, Jada

Source: In The American Journal of Pathology 2010 177(1):311-324

Overexpression of Wild-Type Murine Tau Results in Progressive Tauopathy and Neurodegeneration

Authors: Adams, Stephanie J., Crook, Richard J.P., DeTure, Michael, Randle, Suzanne J., Innes, Amy E., Yu, Xin Z., Lin, Wen-Lang, Dugger, Brittany N., McBride, Melinda, Hutton, Mike, Dickson, Dennis W., McGowan, Eileen

Source: In The American Journal of Pathology 2009 175(4):1598-1609

Tau gene transfer, but not alpha-synuclein, induces both progressive dopamine neuron degeneration and rotational behavior in the rat

Authors: Klein, Ronald L., Dayton, Robert D., Lin, Wen-Lang, Dickson, Dennis W.

Source: In Neurobiology of Disease 2005 20(1):64-73

Aβ42 Is Essential for Parenchymal and Vascular Amyloid Deposition in Mice

Authors: McGowan, Eileen ^*, Pickford, Fiona, Kim, Jungsu, Onstead, Luisa, Eriksen, Jason, Yu, Cindy, Skipper, Lisa, Murphy, M. Paul, Beard, Jenny, Das, Pritam, Jansen, Karen, DeLucia, Michael, Lin, Wen-Lang, Dolios, Georgia, Wang, Rong, Eckman, Christopher B., Dickson, Dennis W., Hutton, Mike, Hardy, John, Golde, Todd ^*

Source: In Neuron 2005 47(2):191-199

Raft-like membrane domains contain enzymatic activities involved in the synthesis of mammalian glycosylphosphatidylinositol anchor intermediates

Authors: Pielsticker, Liza K., Mann, Karl J., Lin, Wen-Lang, Sevlever, Daniel

Source: In Biochemical and Biophysical Research Communications 2005 330(1):163-171

p62 Pathology Model in the Rat Substantia Nigra with Filamentous Inclusions and Progressive Neurodegeneration.

Authors: Jackson, Kasey L.¹, Lin, Wen-Lang², Miriyala, Sumitra³, Dayton, Robert D.¹, Panchatcharam, Manikandan³, McCarthy, Kevin J.^3,4, Castanedes-Casey, Monica², Dickson, Dennis W.², Klein, Ronald L.¹ Klein@lsuhsc.edu

Source: PLoS ONE. 1/11/2017, Vol. 12 Issue 1, p1-17. 17p.

Subject Terms: *NEURODEGENERATION, *NUCLEOPORINS, *INCLUSION body myositis, *SUBSTANTIA nigra, *LABORATORY rats

Apoptosis in oligodendrocytes is associated with axonal degeneration in P301L tau mice

Authors: Zehr, Cindy, Lewis, Jada, McGowan, Eileen, Crook, Julia, Lin, Wen-Lang, Godwin, Kate, Knight, Joshua, Dickson, Dennis W, Hutton, Mike ^*

Source: In Neurobiology of Disease 2004 15(3):553-562

Rapid Neurofibrillary Tangle Formation after Localized Gene Transfer of Mutated Tau

Authors: Klein, Ronald L., Lin, Wen-Lang, Dickson, Dennis W., Lewis, Jada, Hutton, Michael, Duff, Karen, Meyer, Edwin M., King, Michael A.

Source: In The American Journal of Pathology 2004 164(1):347-353