Wogonin Inhibits Ovarian Cancer by Activating the AMPK‐TET2‐5hmC Axis.

Authors: Yang, Shu‐Yi, Jhang, Jing‐Siang, Huang, Wen‐Long, Tsai, Leah H. J., Tsai, Min‐Chia, Chan, Chin‐Pui, Lin, Ru‐Inn, Lin, Hon‐Yi, Li, Chin, Yeh, Chia‐Chou, Chan, Michael W. Y.

Source: Molecular Carcinogenesis; Mar2025, Vol. 64 Issue 3, p440-449, 10p

Targeting PADI2 as a potential therapeutic strategy against metastasis in oral cancer via suppressing EMT-mediated migration and invasion and CCL3/5-induced angiogenesis.

Authors: Hung, Shih-Kai, Yu, Chih-Chia, Lin, Hon-Yi, Chiou, Wen-Yen, Lee, Moon-Sing, Lin, Ru-Inn, Lu, Ming-Chi

Source: Clinical & Experimental Metastasis; Dec2024, Vol. 41 Issue 6, p925-935, 11p

Olaparib enhancing radiosensitization and anti-metastatic effect of oral cancer by targeting IL-17A signal.

Authors: Yu, Chih-Chia, Lin, Hon-Yi, Chan, Michael W.Y., Wu, Shu-Fen, Chiou, Wen-Yen, Lee, Moon-Sing, Chi, Chen-Lin, Lin, Ru-Inn, Hsu, Feng-Chun, Yang, Hsuan-Ju, Chen, Liang-Cheng, Chew, Chia-Hui, Hung, Shih-Kai

Source: Cancer Cell International; 11/11/2024, Vol. 24 Issue 1, p1-13, 13p

Subject Terms: ANTINEOPLASTIC agents, SQUAMOUS cell carcinoma, IONIZING radiation, OLAPARIB, TUMOR growth

Epigenetic modification in radiotherapy and immunotherapy for cancers.

Authors: Hung, Shih-Kai, Lee, Moon-Sing, Chiou, Wen-Yen, Liu, Dai-Wei, Yu, Chih-Chia, Chen, Liang-Cheng, Lin, Ru-Inn, Chew, Chia-Hui, Hsu, Feng-Chun, Yang, Hsuan-Ju, Chan, Michael W. Y., Lin, Hon-Yi

Source: Tzu Chi Medical Journal; Oct-Dec2024, Vol. 36 Issue 4, p396-406, 11p

Subject Terms: STEREOTACTIC radiotherapy, PROGNOSIS, RADIOTHERAPY complications, STEREOTACTIC radiosurgery, LIVER tumors

Transportin-SR2 Mediates Nuclear Import of Phosphorylated SR Proteins

Authors: Lai, Ming-Chih, Lin, Ru-Inn, Tarn, Woan-Yuh

Source: Proceedings of the National Academy of Sciences of the United States of America, 2001 Aug . 98(18), 10154-10159.

Access URL: https://www.jstor.org/stable/3056499

Cyproheptadine exhibits antitumor activity in urothelial carcinoma cells by targeting GSK3β to suppress mTOR and β-catenin signaling pathways

Authors: Hsieh, Hsiao-Yen, Shen, Cheng-Huang, Lin, Ru-Inn, Feng, Yu-Min, Huang, Shih-Yuan, Wang, Yuan-Hung, Wu, Shu-Fen, Hsu, Cheng-Da ^*, Chan, Michael W.Y. ^**

Source: In Cancer Letters 1 January 2016 370(1):56-65

Unexpected close surgical margin in resected buccal cancer: Very close margin and DAPK promoter hypermethylation predict poor clinical outcomes

Authors: Lin, Hon-Yi, Huang, Tze-Ta, Lee, Moon-Sing, Hung, Shih-Kai, Lin, Ru-Inn, Tseng, Chih-En, Chang, Shu-Mei, Chiou, Wen-Yen, Hsu, Feng-Chun, Hsu, Wen-Lin, Liu, Dai-Wei, Su, Yu-Chieh, Li, Szu-Chi, Chan, Michael W.Y.

Source: In Oral Oncology April 2013 49(4):336-344

IRAK2, an Immune and Radiation-Response Gene, Correlates with Advanced Disease Features but Predicts Higher Post-Irradiation Local Control in Non-Metastatic and Resected Oral Cancer Patients.

Authors: Yu, Chih-Chia, Lin, Hon-Yi, Hsieh, Chen-Hsi, Chan, Michael W. Y., Chiou, Wen-Yen, Lee, Moon-Sing, Chi, Chen-Lin, Lin, Ru-Inn, Hsu, Feng-Chun, Chen, Liang-Cheng, Chew, Chia-Hui, Yang, Hsuan-Ju, Hung, Shih-Kai

Source: International Journal of Molecular Sciences; Apr2023, Vol. 24 Issue 8, p6903, 12p

Subject Terms: ORAL cancer, CANCER patients, DOSE-response relationship (Radiation), GENE expression, SQUAMOUS cell carcinoma, GENES

Aberrant TGFβ/SMAD4 signaling contributes to epigenetic silencing of a putative tumor suppressor, RunX1T1 in ovarian cancer

Authors: Yeh, Kun-Tu, Chen, Tze-Ho, Yang, Hui-Wen, Chou, Jian-Liang, Chen, Lin-Yu, Yeh, Chia-Ming, Chen, Yu-Hsin, Lin, Ru-Inn, Su, Her-Young, Chen, Gary C.-W., Deatherage, Daniel E., Huang, Yi-Wen, Yan, Pearlly S., Lin, Huey-Jen, Nephew, Kenneth P., Huang, Tim H.-M., Lai, Hung-Cheng, Chan, Michael W.Y.

Source: Epigenetics. 6(6):727-739

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100056844444.0x000001&indx=1&recIds=ETOCvdc_100056844444.0x000001

Identification of a nuclear localization signal in the polo box domain of Plk1

Authors: Lee, Moon-Sing, Huang, Yi-Han, Huang, Shu-Ping, Lin, Ru-Inn, Wu, Shu-Fen, Li, Chin

Source: In BBA - Molecular Cell Research 2009 1793(10):1571-1578

Phosphorylation of Y14 Modulates Its Interaction with Proteins Involved in mRNA Metabolism and Influences Its Methylation

Authors: Hsu, Ia-Wen ^{‡, 1}, Hsu, Min ^{‡, 1}, Li, Chin ^{‡, 2}, Chuang, Tzu-Wei ^{‡, §}, Lin, Ru-Inn ^{‡, 2}, Tarn, Woan-Yuh ^{‡, 3}

Source: In Journal of Biological Chemistry 14 October 2005 280(41):34507-34512

IRAK2, an IL1R/TLR Immune Mediator, Enhances Radiosensitivity via Modulating Caspase 8/3-Mediated Apoptosis in Oral Squamous Cell Carcinoma.

Authors: Yu, Chih-Chia, Chan, Michael W.Y., Lin, Hon-Yi, Chiou, Wen-Yen, Lin, Ru-Inn, Chen, Chien-An, Lee, Moon-Sing, Chi, Chen-Lin, Chen, Liang-Cheng, Huang, Li-Wen, Chew, Chia-Hui, Hsu, Feng-Chun, Yang, Hsuan-Ju, Hung, Shih-Kai

Source: Frontiers in Oncology; 6/23/2021, Vol. 11, p1-11, 11p

Subject Terms: SQUAMOUS cell carcinoma, CASPASES, IONIZING radiation, APOPTOSIS, CELL growth

Cyproheptadine, an epigenetic modifier, exhibits anti-tumor activity by reversing the epigenetic silencing of IRF6 in urothelial carcinoma.

Authors: Jou, Yeong-Chin, Lin, Guan-Ling, Lin, Hon-Yi, Huang, Wan-Hong, Chuang, Yu-Ming, Lin, Ru-Inn, Chen, Pie-Che, Wu, Shu-Fen, Shen, Cheng-Huang, Chan, Michael W. Y.

Source: Cancer Cell International; 4/19/2021, Vol. 21 Issue 1, p1-12, 12p

Subject Terms: TRANSITIONAL cell carcinoma, EPIGENETICS, TUMOR growth, CANCER invasiveness, WESTERN immunoblotting

A Human Importin-β Family Protein, Transportin-SR2, Interacts with the Phosphorylated RS Domain of SR Proteins

Authors: Lai, Ming-Chih ^‡, Lin, Ru-Inn ^‡, Huang, Shin-Yi ^‡, Tsai, Ching-Wei, Tarn, Woan-Yuh ^§

Source: In Journal of Biological Chemistry 17 March 2000 275(11):7950-7957

ZNF671 DNA methylation as a molecular predictor for the early recurrence of serous ovarian cancer.

Authors: Mase, Shoko, Shinjo, Keiko, Totani, Haruhito, Katsushima, Keisuke, Arakawa, Atsushi, Takahashi, Satoru, Lai, Hung‐Cheng, Lin, Ru‐Inn, Chan, Michael W. Y., Sugiura‐Ogasawara, Mayumi, Kondo, Yutaka

Source: Cancer Science; Mar2019, Vol. 110 Issue 3, p1105-1116, 12p

E2F6 functions as a competing endogenous RNA, and transcriptional repressor, to promote ovarian cancer stemness.

Authors: Cheng, Frank H. C., Lin, Hon‐Yi, Hwang, Tzy‐Wei, Chen, Yin‐Chen, Huang, Rui‐Lan, Chang, Chia‐Bin, Yang, Weiqin, Lin, Ru‐Inn, Lin, Ching‐Wen, Chen, Gary C. W., Mai, Shu‐Yuan, Lin, Jora M. J., Chuang, Yu‐Ming, Chou, Jian‐Liang, Kuo, Li‐Wei, Li, Chin, Cheng, Alfred S. L., Lai, Hung‐Cheng, Wu, Shu‐Fen, Tsai, Je‐Chiang

Source: Cancer Science; Mar2019, Vol. 110 Issue 3, p1085-1095, 11p

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