Photodynamic anti-cancer therapy and arachidonic acid metabolism: State of the art in 2024

Alternate Title: Thérapie photodynamique anti-cancéreuse et métabolisme de l’acide arachidonique : état de l’art en 2024 (French)

Authors: Wahnou, Hicham ^a, Limami, Youness ^b, Duval, Raphaël Emmanuel ^c, Ismail, Bassel ^d, Léger, David Yannick ^e, Sol, Vincent ^e, Liagre, Bertrand ^{e, ⁎, 1}

Source: In Annales Pharmaceutiques Françaises February 2025

Antitumoral activity of Caralluma europaea on colorectal and prostate cancer cell lines

Authors: Samiry, Inass, Pinon, Aline, Limami, Youness, Rais, Samira, Zaid, Younes, Oudghiri, Mounia, Liagre, Bertrand, Mtairag, El Mostafa

Source: Journal of toxicology and environmental health.Part A.Current issues. 86(7):230-240

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100177041662.0x000001&indx=1&recIds=ETOCvdc_100177041662.0x000001

PKC-Delta-Dependent Pathways Contribute to the Exacerbation of the Platelet Activity in Crohn's Disease

Authors: Limami, Youness, Senhaji, Nezha, Zaid, Nabil, Khalki, Loubna, Naya, Abdallah, Hajjaj-Hassouni, Najia, Jalali, Farid, Oudghiri, Mounia, Zaid, Younes

Source: Seminars in thrombosis and hemostasis. 48(2):246-250

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Gamma-Tocopherol: A Comprehensive Review of Its Antioxidant, Anti-Inflammatory, and Anticancer Properties.

Authors: Es-Sai, Basma, Wahnou, Hicham, Benayad, Salma, Rabbaa, Soufiane, Laaziouez, Yassir, El Kebbaj, Riad, Limami, Youness, Duval, Raphaël Emmanuel

Source: Molecules; Feb2025, Vol. 30 Issue 3, p653, 20p

Subject Terms: REACTIVE nitrogen species, TUMOR necrosis factors, REACTIVE oxygen species, PROSTATE cancer, OXIDATIVE stress, LUNGS

Curcumin-Based Nanoparticles: Advancements and Challenges in Tumor Therapy.

Authors: Wahnou, Hicham, El Kebbaj, Riad, Liagre, Bertrand, Sol, Vincent, Limami, Youness, Duval, Raphaël Emmanuel

Source: Pharmaceutics; Jan2025, Vol. 17 Issue 1, p114, 42p

Subject Terms: TREATMENT effectiveness, TURMERIC, INHIBITION of cellular proliferation, CANCER treatment, TUMOR treatment, CURCUMIN, BREAST

Ursolic Acid's Alluring Journey: One Triterpenoid vs. Cancer Hallmarks.

Authors: Limami, Youness^1,2 (AUTHOR) hwwahnou@gmail.com, Pinon, Aline³ (AUTHOR) aline.pinon@unilim.fr, Wahnou, Hicham² (AUTHOR) mounia.oudghiri@univh2c.ma, Oudghiri, Mounia² (AUTHOR), Liagre, Bertrand³ (AUTHOR) bertrand.liagre@unilim.fr, Simon, Alain³ (AUTHOR), Duval, Raphaël Emmanuel⁴ (AUTHOR) youness.limami@uhp.ac.ma

Source: Molecules. Dec2023, Vol. 28 Issue 23, p7897. 16p.

Subject Terms: *URSOLIC acid, *WNT signal transduction, *BREAST, *CELL growth, *CANCER cells, *ANTINEOPLASTIC agents, *CELLULAR signal transduction

Ibuprofen-loaded calcium phosphate granules: A new bone substitute for local relieving symptoms of osteoarthritis

Authors: Limami, Youness, Leger, David Yannick, Liagre, Bertrand, Pécout, Nathalie, Viana, Marylène

Source: In European Journal of Pharmaceutical Sciences 1 March 2021 158

Integrating ADMET, enrichment analysis, and molecular docking approach to elucidate the mechanism of Artemisia herba alba for the treatment of inflammatory bowel disease-associated arthritis.

Authors: Wahnou, Hicham, Hmimid, Fouzia, Errami, Ahmed, Nait Irahal, Imane, Limami, Youness, Oudghiri, Mounia

Source: Journal of Toxicology & Environmental Health: Part A; 2024, Vol. 87 Issue 20, p836-854, 19p

Subject Terms: INFLAMMATORY bowel diseases, CINNAMIC acid, MOLECULAR docking, BIOACTIVE compounds, DRUG target, CHLOROGENIC acid

Oxford-AstraZeneca ChAdOx1 COVID-19 Vaccine Does Not Alter Platelet Aggregation

Authors: Limami, Youness, Khalki, Loubna, Zaid, Nabil, Khyatti, Meriem, Turk, Joumana, Ammara, Mounia, Mtairag, El, Oudghiri, Mounia, Naya, Abdallah, Taberkant, Mustapha, Zaid, Younes

Source: Seminars in thrombosis and hemostasis. 48(1):109-111

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100191788176.0x000001&indx=1&recIds=ETOCvdc_100191788176.0x000001

Platelets Can Associate With SARS-CoV-2 RNA and Are Hyperactivated in COVID-19

Authors: Zaid, Younes, Puhm, Florian, Allaeys, Isabelle, Naya, Abdallah, Oudghiri, Mounia, Khalki, Loubna, Limami, Youness, Zaid, Nabil, Sadki, Khalid, Ben El Haj, Rafiqua, Mahir, Wissal, Belayachi, Lamiae, Belefquih, Bouchra, Benouda, Amina, Cheikh, Amine, Langlois, Marc-André, Cherrah, Yahia, Flamand, Louis, Guessous, Fadila, Boilard, Eric

Source: Circulation research. 127(11):1404-1418

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100190150011.0x000001&indx=1&recIds=ETOCvdc_100190150011.0x000001

Current antiplatelet agents, new inhibitors and therapeutic targets

Authors: El Alaoui, Mustapha Zine, Guy, Alexandre, Khalki, Loubna, Limami, Youness, Benomar, Ali, Zaid, Nabil, Cherrah, Yahia, Cadi, Rachida, Zaid, Younes

Source: M/S. 36(4):348-357

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCRN623379703&indx=1&recIds=ETOCRN623379703

Antioxidant Effects of Cactus Seed Oil against Iron-Induced Oxidative Stress in Mouse Liver, Brain and Kidney.

Authors: Bouchab, Habiba, Ishaq, Abbas, Limami, Youness, Saretzki, Gabriele, Nasser, Boubker, El Kebbaj, Riad

Source: Molecules; Sep2024, Vol. 29 Issue 18, p4463, 15p

Subject Terms: RAPESEED oil, FERROUS sulfate, REACTIVE oxygen species, IRON overload, DNA damage

Synthesis and Antiproliferative Effect of 3,4,5-Trimethoxylated Chalcones on Colorectal and Prostatic Cancer Cells.

Authors: Letulle, Cécile, Toublet, François-Xavier, Pinon, Aline, Hba, Soufyane, Laurent, Aurélie, Sol, Vincent, Fagnère, Catherine, Rioux, Benjamin, Allais, Florent, Michallet, Sophie, Lafanechère, Laurence, Limami, Youness, Oudghiri, Mounia, Othman, Mohamed, Daïch, Adam, Liagre, Bertrand, Lawson, Ata Martin, Pouget, Christelle

Source: Pharmaceuticals (14248247); Sep2024, Vol. 17 Issue 9, p1207, 24p

Subject Terms: PROSTATE cancer, CHALCONES, CHROMONES, CANCER cells, COLORECTAL cancer, CHALCONE

Orbea variegata (L.) Haw in skin carcinogenesis: insights from an in vivo male Swiss mouse model study.

Authors: Chgari, Oumaima, Wahnou, Hicham, Ndayambaje, Martin, Moukhfi, Fatimazahra, Benkhnigue, Ouafae, Marnissi, Farida, Limami, Youness, Oudghiri, Mounia

Source: Journal of Toxicology & Environmental Health: Part A; 2024, Vol. 87 Issue 15, p630-645, 16p

Subject Terms: PHYTOCHEMICALS, LABORATORY mice, ASPARTATE aminotransferase, ANIMAL disease models, SAPONINS, NUCLEAR nonproliferation, HAWTHORNS, ORNAMENTAL plants

Sulfuric acid‐induced skin neoplasms in immunocompetent mice.

Authors: Chgari, Oumaima, Marnissi, Farida, Moukhfi, Fatimazahra, Ndayambaje, Martin, Wahnou, Hicham, Limami, Youness, Karkouri, Mehdi, Oudghiri, Mounia

Source: Experimental Dermatology; Aug2024, Vol. 33 Issue 8, p1-8, 8p

Subject Terms: SKIN tumors, HAIR follicles, SULFURIC acid, OXIDATIVE stress, IMMUNOHISTOCHEMISTRY

Resistance to ursolic acid-induced apoptosis through involvement of melanogenesis and COX-2/PGE2 pathways in human M4Beu melanoma cancer cells

Authors: Hassan, Lama, Pinon, Aline, Limami, Youness, Seeman, Josiane, Fidanzi-Dugas, Chloe, Martin, Frederique, Badran, Bassam, Simon, Alain, Liagre, Bertrand

Source: In Experimental Cell Research 1 July 2016 345(1):60-69

Flavonoids and Flavonoid-Based Nanoparticles for Osteoarthritis and Rheumatoid Arthritis Management.

Authors: Wahnou, Hicham¹ hwwahnou@gmail.com, Limami, Youness^1,2 hwwahnou@gmail.com, Oudghiri, Mounia¹ hwwahnou@gmail.com

Source: BioChem. Mar2024, Vol. 4 Issue 1, p38-61. 24p.

Subject Terms: *FLAVONOIDS, *NANOPARTICLES, *OSTEOARTHRITIS treatment, *RHEUMATOID arthritis treatment, *MEDICINAL plants

The Potential Role of Major Argan Oil Compounds as Nrf2 Regulators and Their Antioxidant Effects.

Authors: El Kebbaj, Riad, Bouchab, Habiba, Tahri-Joutey, Mounia, Rabbaa, Soufiane, Limami, Youness, Nasser, Boubker, Egbujor, Melford C., Tucci, Paolo, Andreoletti, Pierre, Saso, Luciano, Cherkaoui-Malki, Mustapha

Source: Antioxidants; Mar2024, Vol. 13 Issue 3, p344, 21p

Subject Terms: NUCLEAR factor E2 related factor, OXIDOREDUCTASES, NAD (Coenzyme)

Geographic Terms: MOROCCO

Exploring the multifaceted effects of Ammi visnaga: subchronic toxicity, antioxidant capacity, immunomodulatory, and anti-inflammatory activities.

Authors: Ndayambaje, Martin, Wahnou, Hicham, Sow, Marieme, Chgari, Oumaima, Habyarimana, Thierry, Karkouri, Mehdi, Limami, Youness, Naya, Abdallah, Oudghiri, Mounia

Source: Journal of Toxicology & Environmental Health: Part A; 2024, Vol. 87 Issue 4, p150-165, 16p

Subject Terms: PHYTOCHEMICALS, OXIDANT status, LEUKOCYTE count, ANTI-inflammatory agents, MOLECULAR docking, IMMUNOGLOBULINS, LABORATORY mice

Natural Chalcones and Derivatives in Colon Cancer: Pre-Clinical Challenges and the Promise of Chalcone-Based Nanoparticles.

Authors: Hba, Soufyane, Ghaddar, Suzan, Wahnou, Hicham, Pinon, Aline, El Kebbaj, Riad, Pouget, Christelle, Sol, Vincent, Liagre, Bertrand, Oudghiri, Mounia, Limami, Youness

Source: Pharmaceutics; Dec2023, Vol. 15 Issue 12, p2718, 20p

Subject Terms: COLON cancer, CHALCONES, CHALCONE, DRUG delivery systems, NANOPARTICLES