Targeting purine synthesis in ASS1-expressing tumors enhances the response to immune checkpoint inhibitors

Authors: Keshet, Rom, Lee, Joo Sang, Adler, Lital, Iraqi, Muhammed, Ariav, Yarden, Lim, Lisha Qiu Jin, Lerner, Shaul, Rabinovich, Shiran, Oren, Roni, Katzir, Rotem, Weiss Tishler, Hila, Stettner, Noa, Goldman, Omer, Landesman, Hadas, Galai, Sivan, Kuperman, Yael, Kuznetsov, Yuri, Brandis, Alexander, Mehlman, Tevi, Malitsky, Sergey, Itkin, Maxim, Koehler, S. Eleonore, Zhao, Yongmei, Talsania, Keyur, Shen, Tsai-wei, Peled, Nir, Ulitsky, Igor, Porgador, Angel, Ruppin, Eytan, Erez, Ayelet

Source: Nature cancer. 1(9):894-908

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100172462850.0x000001&indx=1&recIds=ETOCvdc_100172462850.0x000001

A secretion-enhancing cis regulatory targeting element (SECReTE) involved in mRNA localization and protein synthesis.

Authors: Cohen-Zontag, Osnat¹, Baez, Camila¹, Lim, Lisha Qiu Jin¹, Olender, Tsviya¹, Schirman, Dvir¹, Dahary, Dvir¹, Pilpel, Yitzhak¹, Gerst, Jeffrey E.¹

Source: PLoS Genetics; 7/1/2019, Vol. 15 Issue 7, p1-36, 36p