Limited Expansion of Human Hepatocytes in FAH/RAG2-Deficient Swine

Authors: Nelson, Erek David, Larson, Ellen, Joo, Dong Jin, Mao, Shennen, Glorioso, Jaime, Abu Rmilah, Anan, Zhou, Wei, Jia, Yao, Mounajjed, Taofic, Shi, Min, Bois, Melanie, Wood, Adam, Jin, Fang, Whitworth, Kristin, Wells, Kevin, Spate, Anna, Samuel, Melissa, Minshew, Anna, Walters, Eric, Rinaldo, Piero, Lillegard, Joseph B., Johnson, Aaron, Amiot, Bruce, Hickey, Raymond, Prather, Randall, Platt, Jeffrey L., Nyberg, Scott L.

Source: Tissue engineering.Part A. 28(3/4):150-160

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100141254402.0x000001&indx=1&recIds=ETOCvdc_100141254402.0x000001

Placental Location in Maternal-Fetal Surgery for Myelomeningocele

Authors: Lillegard, Joseph B., Eyerly-Webb, Stephanie A., Watson, David A., Bahtiyar, Mert Ozan, Bennett, Kelly A., Emery, Stephen P., Fisher, Allan J., Goldstein, Ruth B., Goodnight, William H., Lim, Foong-Yen, McCullough, Laurence B., Moehrlen, Ueli, Moldenhauer, Julie S., Moon-Grady, Anita J., Ruano, Rodrigo, Skupski, Daniel W., Treadwell, Marjorie C., Tsao, KuoJen, Wagner, Amy J., Zaretsky, Michael V.

Source: Fetal diagnosis and therapy. 49(3):117-124

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100150185850.0x000001&indx=1&recIds=ETOCvdc_100150185850.0x000001

Risk factors for perioperative hypothermia and infectious outcomes in gastroschisis patients

Authors: Bence, Christina M., Landisch, Rachel M., Wu, Ruizhe, Szabo, Aniko, McElhinney, Kathryn, Austin, Mary T., Fraser, Jason D., St. Peter, Shawn D., Joshi, Shilvi, Lillegard, Joseph B., Tay, Shirli, Warner, Brad W., Kim, Aimee G., Perrone, Erin E., Leys, Charles M., Kohler, Jonathan E., Wagner, Amy J.

Source: In Journal of Pediatric Surgery July 2021 56(7):1107-1112

Use of an adeno‐associated virus serotype Anc80 to provide durable cure of phenylketonuria in a mouse model

Authors: Kaiser, Robert A., Weber, Nicholas D., Trigueros‐Motos, Laia, Allen, Kari L., Martinez, Michael, Cao, William, VanLith, Caitlin J., Hillin, Lori G., Douar, Anne, González‐Aseguinolaza, Gloria, Aldabe, Rafael, Lillegard, Joseph B.

Source: Journal of inherited metabolic disease. 44(6):1369-1381

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100141220453.0x000001&indx=1&recIds=ETOCvdc_100141220453.0x000001

North American Fetal Therapy Network: Maternal Outcomes in Fetal Aqueductal Stenosis.

Authors: Emery, Stephen P., Lopa, Samia, Peterson, Erika, Miller, Jena L., Treadwell, Marjorie C., Gebb, Juliana, Galan, Henry, Bergh, Eric P., Criebaum, Amanda, McLennan, Amelia, Lillegard, Joseph B., Blumenfeld, Yair J., Turan, Ozhan M., Streitman, David C.

Source: Fetal Diagnosis & Therapy; 2024, Vol. 51 Issue 6, p612-616, 5p

Subject Terms: CESAREAN section, PREMATURE labor, PREGNANCY complications, CEREBROSPINAL fluid, CENTRAL nervous system

Ex Vivo Cell Therapy by Ectopic Hepatocyte Transplantation Treats the Porcine Tyrosinemia Model of Acute Liver Failure

Authors: Nicolas, Clara T., Kaiser, Robert A., Hickey, Raymond D., Allen, Kari L., Du, Zeji, VanLith, Caitlin J., Guthman, Rebekah M., Amiot, Bruce, Suksanpaisan, Lukkana, Han, Bing, Francipane, Maria Giovanna, Cheikhi, Amin, Jiang, Huailei, Bansal, Aditya, Pandey, Mukesh K., Garg, Ishan, Lowe, Val, Bhagwate, Aditya, O’Brien, Daniel, Kocher, Jean-Pierre A., DeGrado, Timothy R., Nyberg, Scott L., Lagasse, Eric, Lillegard, Joseph B.

Source: In Molecular Therapy - Methods & Clinical Development 11 September 2020 18:738-750

The future of gene-targeted therapy for hereditary tyrosinemia type 1 as a lead indication among the inborn errors of metabolism

Authors: Thompson, Whitney S., Mondal, Gourish, Vanlith, Caitlin J., Kaiser, Robert A., Lillegard, Joseph B.

Source: Expert opinion on orphan drugs. 8(7):245-256

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100111085287.0x000001&indx=1&recIds=ETOCvdc_100111085287.0x000001

Continuous Fetal Cardiac Monitoring during Fetoscopic Myelomeningocele Repair and Relationship to Spectral Doppler Changes.

Authors: Eyerly-Webb, Stephanie A., Howley, Lisa, Brock, Clifton O., Lillegard, Joseph B., Fisher, James, Reynolds, Benjamin, Barthel, Emily F., Dion, Eric, Snowise, Saul

Source: Fetal Diagnosis & Therapy; 2024, Vol. 51 Issue 4, p357-364, 8p

Subject Terms: FETAL heart rate, FETAL surgery, LEFT ventricular dysfunction, DUCTUS arteriosus, TRICUSPID valve, FETAL echocardiography, DOPPLER echocardiography

Hepatocyte spheroids as an alternative to single cells for transplantation after ex vivo gene therapy in mice and pig models

Authors: Nicolas, Clara T., Hickey, Raymond D., Allen, Kari L., Du, Zeji, Guthman, Rebekah M., Kaiser, Robert A., Amiot, Bruce, Bansal, Aditya, Pandey, Mukesh K., Suksanpaisan, Lukkana, DeGrado, Timothy R, Nyberg, Scott L., Lillegard, Joseph B.

Source: In Surgery September 2018 164(3):473-481

Fetoscopy-Assisted Percutaneous Decompression of the Distal Trachea and Lungs Reverses Hydrops Fetalis and Fetal Distress in a Fetus with Laryngeal Atresia

Authors: Nicolas, Clara T., Lynch-Salamon, David, Bendel-Stenzel, Ellen, Tibesar, Robert, Luks, Francois, Eyerly-Webb, Stephanie, Lillegard, Joseph B.

Source: Fetal diagnosis and therapy. 46(1):75-80

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100085273615.0x000001&indx=1&recIds=ETOCvdc_100085273615.0x000001

Ex Vivo Hepatocyte Reprograming Promotes Homology‐Directed DNA Repair to Correct Metabolic Disease in Mice After Transplantation

Authors: VanLith, Caitlin J., Guthman, Rebekah M., Nicolas, Clara T., Allen, Kari L., Liu, Yuanhang, Chilton, Jennifer A., Tritz, Zachariah P., Nyberg, Scott L., Kaiser, Robert A., Lillegard, Joseph B., Hickey, Raymond D.

Source: Hepatology Communications. 3(4):558-573

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100090563428.0x000001&indx=1&recIds=ETOCvdc_100090563428.0x000001

Chronic Phenotype Characterization of a Large-Animal Model of Hereditary Tyrosinemia Type 1

Authors: Elgilani, Faysal, Mao, Shennen A., Glorioso, Jaime M., Yin, Meng, Iankov, Ianko D., Singh, Anisha, Amiot, Bruce, Rinaldo, Piero, Marler, Ronald J., Ehman, Richard L., Grompe, Markus, Lillegard, Joseph B., Hickey, Raymond D., Nyberg, Scott L.

Source: In The American Journal of Pathology January 2017 187(1):33-41

Curative Ex Vivo Hepatocyte-Directed Gene Editing in a Mouse Model of Hereditary Tyrosinemia Type 1

Authors: VanLith, Caitlin, Guthman, Rebekah, Nicolas, Clara T., Allen, Kari, Du, Zeji, Joo, Dong Jin, Nyberg, Scott L., Lillegard, Joseph B., Hickey, Raymond D.

Source: Human gene therapy. 29(11):1315-1326

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100071775880.0x000001&indx=1&recIds=ETOCvdc_100071775880.0x000001

Fumarylacetoacetate hydrolase deficient pigs are a novel large animal model of metabolic liver disease

Authors: Hickey, Raymond D., Mao, Shennen A., Glorioso, Jaime, Lillegard, Joseph B., Fisher, James E., Amiot, Bruce, Rinaldo, Piero, Harding, Cary O., Marler, Ronald, Finegold, Milton J., Grompe, Markus, Nyberg, Scott L.

Source: In Stem Cell Research July 2014 13(1):144-153

Autologous blood patch for persistent air leak in children

Authors: Lillegard, Joseph B., Kennedy, Raelene D., Ishitani, Michael B., Zarroug, Abdalla E., Feltis, Brad

Source: In Journal of Pediatric Surgery September 2013 48(9):1862-1866

Role of Kupffer cells and toll-like receptor 4 in acetaminophen-induced acute liver failure

Authors: Fisher, James E., McKenzie, Travis J., Lillegard, Joseph B., Yu, Yue, Juskewitch, Justin E., Nedredal, Geir I., Brunn, Gregory J., Yi, Eunhee S., Malhi, Harmeet, Smyrk, Thomas C., Nyberg, Scott L.

Source: In Journal of Surgical Research March 2013 180(1):147-155

Hepatic Resection for the Carcinoid Syndrome in Patients with Severe Carcinoid Heart Disease: Does Valve Replacement Permit Safe Hepatic Resection?

Authors: Lillegard, Joseph B., Fisher, James E., Mckenzie, Travis J., Que, Florencia G., Farnell, Michael B., Kendrick, Michael L., Donohue, John H., Reid-Lombardo, Kaye, Schaff, Hartzell V., Connolly, Heidi M., Nagorney, David M.

Source: In Journal of the American College of Surgeons 2011 213(1):130-136

Recognition of Candida albicans by Mannan-Binding Lectin in vitro and in vivo

Authors: Lillegard, Joseph B., Sim, Robert B., Thorkildson, Peter, Gates, Marcellene A., Kozel, Thomas R.

Source: The Journal of Infectious Diseases, 2006 Jun 01. 193(11), 1589-1597.

Access URL: https://www.jstor.org/stable/30086617

Aldosteronomas—State of the Art

Authors: McKenzie, Travis J., Lillegard, Joseph B., Young, William F., Jr., Thompson, Geoffrey B.

Source: In Surgical Clinics of North America 2009 89(5):1241-1253

In vivo lentiviral vector gene therapy to cure hereditary tyrosinemia type 1 and prevent development of precancerous and cancerous lesions.

Authors: Nicolas, Clara T., VanLith, Caitlin J., Hickey, Raymond D., Du, Zeji, Hillin, Lori G., Guthman, Rebekah M., Cao, William J., Haugo, Benjamin, Lillegard, Annika, Roy, Diya, Bhagwate, Aditya, O'Brien, Daniel, Kocher, Jean-Pierre, Kaiser, Robert A., Russell, Stephen J., Lillegard, Joseph B.

Source: Nature Communications; 8/25/2022, Vol. 13 Issue 1, p1-15, 15p

Subject Terms: TRANSGENE expression, GENE therapy, HEPATIC fibrosis, PRECANCEROUS conditions, INBORN errors of metabolism, ANIMAL diseases