Characterizing uveal melanoma patients with peritoneal metastases: A retrospective single-center analysis

Authors: Rosnev, Stanislav ^a, Peuker, Caroline A. ^{a, b}, Piwonski, Iris ^c, Ihlow, Jana ^{b, c}, Leyvraz, Serge ^a, Klingberg, Jonas ^a, Horst, David ^c, Joosten, Maria ^c, Möbs, Markus ^c, Joussen, Antonia M. ^d, de Bucourt, Maximilian ^e, Keilholz, Ulrich ^{f, g}, Keller, Ulrich ^{a, g, h}, Ochsenreither, Sebastian ^{a, f, g}, Rittig, Susanne M. ^{a, b, ⁎}

Source: In European Journal of Cancer 11 March 2025 218

A three-arm randomised phase II study of the MEK inhibitor selumetinib alone or in combination with paclitaxel in metastatic uveal melanoma

Authors: Sacco, Joseph J., Jackson, Richard, Corrie, Pippa, Danson, Sarah, Evans, T.R. Jeffry, Ochsenreither, Sebastian, Kumar, Satish, Goodman, Andrew, Larkin, James, Karydis, Ioannis, Steven, Neil, Lorigan, Paul, Plummer, Ruth, Patel, Poulam, Psarelli, Eftychia, Olsson-Brown, Anna, Shaw, Heather, Leyvraz, Serge, Handley, Louise, Rawcliffe, Charlotte, Nathan, Paul

Source: In European Journal of Cancer May 2024 202

Tumour mutational burden and survival with molecularly matched therapy

Authors: de Bortoli, Till, Benary, Manuela, Horak, Peter, Lamping, Mario, Stintzing, Sebastian, Tinhofer, Ingeborg, Leyvraz, Serge, Schäfer, Reinhold, Klauschen, Frederick, Keller, Ulrich, Stenzinger, Albrecht, Fröhling, Stefan, Kurzrock, Razelle, Keilholz, Ulrich, Rieke, Damian T., Jelas, Ivan

Source: In European Journal of Cancer September 2023 190

Support of a molecular tumour board by an evidence-based decision management system for precision oncology

Authors: Lamping, Mario, Benary, Manuela, Leyvraz, Serge, Messerschmidt, Clemens, Blanc, Eric, Kessler, Thomas, Schütte, Moritz, Lenze, Dido, Jöhrens, Korinna, Burock, Susen, Klinghammer, Konrad, Ochsenreither, Sebastian, Sers, Christine, Schäfer, Reinhold, Tinhofer, Ingeborg, Beule, Dieter, Klauschen, Frederick, Yaspo, Marie-Laure, Keilholz, Ulrich, Rieke, Damian T.

Source: In European Journal of Cancer March 2020 127:41-51

Base-excision repair pathway shapes 5-methylcytosine deamination signatures in pan-cancer genomes.

Authors: Silveira, André Bortolini, Houy, Alexandre, Ganier, Olivier, Özemek, Begüm, Vanhuele, Sandra, Vincent-Salomon, Anne, Cassoux, Nathalie, Mariani, Pascale, Pierron, Gaelle, Leyvraz, Serge, Rieke, Damian, Picca, Alberto, Bielle, Franck, Yaspo, Marie-Laure, Rodrigues, Manuel, Stern, Marc-Henri

Source: Nature Communications; 11/14/2024, Vol. 15 Issue 1, p1-17, 17p

A diagnostic challenge of KIT p.V559D and BRAF p.G469A mutations in a paragastric mass.

Authors: Habringer, Stefan, Ihlow, Jana, Kleo, Karsten, Klostermann, Anna, Schmidt, Max, Chai, Lidan, Knödler, Maren, Leyvraz, Serge, Sigler, Christian, Sinn, Bruno, Maschmeyer, Georg, Jegodka, Yvette, Benary, Manuela, Ott, Claus-Eric, Tinhofer, Ingeborg, Schäfer, Reinhold, Möbs, Markus, Keller, Ulrich, Keilholz, Ulrich, Rieke, Damian T

Source: Oncologist; Oct2024, Vol. 29 Issue 10, p908-912, 5p

Subject Terms: THERAPEUTIC use of antineoplastic agents, GASTROINTESTINAL tumors, CANCER invasiveness, DIFFERENTIAL diagnosis, COMPUTED tomography, TREATMENT effectiveness, TRANSFERASES, GENETIC mutation, GENETIC testing, GENOTYPES

Validation of a Prognostic Staging for Metastatic Uveal Melanoma: A Collaborative Study of the European Ophthalmic Oncology Group

Authors: Kivelä, Tero T., Piperno-Neumann, Sophie, Desjardins, Laurence, Schmittel, Alexander, Bechrakis, Nikolaos, Midena, Edoardo, Leyvraz, Serge, Zografos, Leonidas, Grange, Jean-Daniel, Ract-Madoux, Guillaume, Marshall, Ernest, Damato, Bertil, Eskelin, Sebastian

Source: In American Journal of Ophthalmology August 2016 168:217-226

Radiotherapy for GIST progressing during or after tyrosine kinase inhibitor therapy: A prospective study

Authors: Joensuu, Heikki, Eriksson, Mikael, Collan, Juhani, Balk, Marja H., Leyvraz, Serge, Montemurro, Michael

Source: In Radiotherapy and Oncology August 2015 116(2):233-238

Clinical trial designs for rare diseases: Studies developed and discussed by the International Rare Cancers Initiative

Authors: Bogaerts, Jan, Sydes, Matthew R., Keat, Nicola, McConnell, Andrea, Benson, Al, Ho, Alan, Roth, Arnaud, Fortpied, Catherine, Eng, Cathy, Peckitt, Clare, Coens, Corneel, Pettaway, Curtis, Arnold, Dirk, Hall, Emma, Marshall, Ernie, Sclafani, Francesco, Hatcher, Helen, Earl, Helena, Ray-Coquard, Isabelle, Paul, James, Blay, Jean-Yves, Whelan, Jeremy, Panageas, Kathy, Wheatley, Keith, Harrington, Kevin, Licitra, Lisa, Billingham, Lucinda, Hensley, Martee, McCabe, Martin, Patel, Poulam M., Carvajal, Richard, Wilson, Richard, Glynne-Jones, Rob, McWilliams, Rob, Leyvraz, Serge, Rao, Sheela, Nicholson, Steve, Filiaci, Virginia, Negrouk, Anastassia, Lacombe, Denis, Dupont, Elisabeth, Pauporté, Iris, Welch, John J., Law, Kate, Trimble, Ted, Seymour, Matthew

Source: In European Journal of Cancer February 2015 51(3):271-281

Updated efficacy and safety of larotrectinib (laro) in patients (pts) with TRK fusion gastrointestinal (GI) cancer.

Authors: Shen, Lin¹ (AUTHOR), Andre, Thierry² (AUTHOR), Chung, Hyun Cheol Cheol³ (AUTHOR), Deeken, John F.⁴ (AUTHOR), Garralda, Elena⁵ (AUTHOR), Italiano, Antoine⁶ (AUTHOR), Leyvraz, Serge⁷ (AUTHOR), Liu, Tianshu⁸ (AUTHOR), Burcoveanu, Domnita-Ileana⁹ (AUTHOR), Grugel, Robin¹⁰ (AUTHOR), Mussi, Chiara E.¹¹ (AUTHOR), Xu, Rui-Hua¹² (AUTHOR), Hong, David S.¹³ (AUTHOR), Drilon, Alexander E.¹⁴ (AUTHOR), Berlin, Jordan¹⁵ (AUTHOR)

Source: Journal of Clinical Oncology. 2024 Supplement 3, Vol. 42, p109-109. 235p.

Larotrectinib efficacy and safety in adult patients with tropomyosin receptor kinase fusion sarcomas.

Authors: Kummar, Shivaani, Shen, Lin, Hong, David S., McDermott, Ray, Keedy, Vicki L., Casanova, Michela, Demetri, George D., Dowlati, Afshin, Melcón, Soledad Gallego, Lassen, Ulrik N., Leyvraz, Serge, Liu, Tianshu, Moreno, Victor, Patel, Jyoti, Patil, Tejas, Mallick, Atrayee Basu, Sousa, Nuno, Tahara, Makoto, Ziegler, David S., Norenberg, Ricarda

Source: Cancer (0008543X); Dec2023, Vol. 129 Issue 23, p3772-3782, 11p

Subject Terms: TROPOMYOSINS, PATIENT safety, SARCOMA, OSTEOSARCOMA, CHILD patients

EORTC Melanoma Group achievements

Authors: Testori, Alessandro, Suciu, Stefan, van Akkooi, Alexander C.J., Cook, Martin, Ghanem, Ghanem, Karra Gurunath, R., Keilholz, Ulrich, van Kempen, Leon, Leyvraz, Serge, Mihm, Martin, Newton-Bishop, Julia, Patel, Poulam, Robert, Caroline, Schadendorf, Dirk, de Schaetzen, Gaetan, Spatz, Alan, de Vries, Esther, Eggermont, Alexander M.M.

Source: In EJC Supplements March 2012 10(1):112-119

Breast sarcomas: Current and future perspectives

Authors: Voutsadakis, Ioannis A., Zaman, Khalil, Leyvraz, Serge

Source: In The Breast 2011 20(3):199-204

Phase II study of weekly plitidepsin as second-line therapy for small cell lung cancer

Authors: Eisen, Tim, Thatcher, Nick, Leyvraz, Serge, Miller, Wilson H., Jr., Couture, Felix, Lorigan, Paul, Lüthi, François, Small, David, Tanovic, Adnan, O’Brien, Mary

Source: In Lung Cancer 2009 64(1):60-65

Epithelioid Soft Tissue Tumors

Authors: Dei Tos, A. Paolo, Wagner, Andrew J., Modena, Piergiorgio, Comandone, Alessandro, Leyvraz, Serge

Source: In Seminars in Oncology 2009 36(4):347-357

Genomic and transcriptomic landscape of conjunctival melanoma.

Authors: Cisarova, Katarina^1,2, Folcher, Marc^3,4, El Zaoui, Ikram¹, Pescini-Gobert, Rosanna¹, Peter, Virginie G.^2,3,4, Royer-Bertrand, Beryl¹, Zografos, Leonidas⁵, Schalenbourg, Ann⁵, Nicolas, Michael⁵, Rimoldi, Donata⁶, Leyvraz, Serge⁷, Riggi, Nicolò⁸, Moulin, Alexandre P.⁵, Rivolta, Carlo^2,3,4, carlo.rivolta@iob.ch

Source: PLoS Genetics; 12/31/2020, Vol. 16 Issue 12, p1-22, 22p

Challenges in the Diagnosis of NTRK Fusion-Positive Cancers

Authors: Gautschi, Oliver, Bubendorf, Lukas, Leyvraz, Serge, Menon, Roopika, Diebold, Joachim

Source: In Journal of Thoracic Oncology July 2020 15(7):e108-e110

Genetic abnormalities and survival in multiple myeloma: the experience of the Intergroupe Francophone du Myélome

Authors: Avet-Loiseau, Hervé ^*, Attal, Michel, Moreau, Philippe, Charbonnel, Catherine, Garban, Frédéric, Hulin, Cyrille, Leyvraz, Serge, Michallet, Mauricette, Yakoub-Agha, Ibrahim, Garderet, Laurent, Marit, Gérald, Michaux, Lucienne, Voillat, Laurent, Renaud, Marc, Grosbois, Bernard, Guillerm, Gaelle, Benboubker, Lotfi, Monconduit, Mathieu, Thieblemont, Catherine, Casassus, Philippe, Caillot, Denis, Stoppa, Anne-Marie, Sotto, Jean-Jacques, Wetterwald, Marc, Dumontet, Charles, Fuzibet, Jean-Gabriel, Azais, Isabelle, Dorvaux, Véronique, Zandecki, Marc, Bataille, Régis, Minvielle, Stéphane, Harousseau, Jean-Luc, Facon, Thierry, Mathiot, Claire

Source: In Blood 15 April 2007 109(8):3489-3495

Maintenance therapy with thalidomide improves survival in patients with multiple myeloma

Authors: Attal, Michel, Harousseau, Jean-Luc, Leyvraz, Serge, Doyen, Chantal, Hulin, Cyrille, Benboubker, Lofti, Agha, Ibrahim Yakoub, Bourhis, Jean-Henri, Garderet, Laurent, Pegourie, Brigitte, Dumontet, Charles, Renaud, Marc, Voillat, Laurent, Berthou, Christian, Marit, Gerald, Monconduit, Mathieu, Caillot, Denis, Grobois, Bernard, Avet-Loiseau, Herve, Moreau, Philippe, Facon, Thierry, for the Inter-Groupe Francophone du Myélome (IFM)

Source: In Blood 15 November 2006 108(10):3289-3294

KIT mutations and dose selection for imatinib in patients with advanced gastrointestinal stromal tumours

Authors: Debiec-Rychter, Maria, Sciot, Raf, Le Cesne, Axel, Schlemmer, Marcus, Hohenberger, Peter, van Oosterom, Allan T., Blay, Jean-Yves, Leyvraz, Serge, Stul, Michel, Casali, Paolo G., Zalcberg, John, Verweij, Jaap, Van Glabbeke, Martine, Hagemeijer, Anne, Judson, Ian

Source: In European Journal of Cancer 2006 42(8):1093-1103