Stereoisomers of cannabidiols and their pharmacological activities – A potentially novel direction for cannabinoids

Authors: Rao, Vajja Krishna ^a, Lewis-Bakker, Melissa M. ^a, Wasilewski, Ewa ^a, Clarke, Hance A. ^{b, c}, Kotra, Lakshmi P. ^{a, b, d, ⁎}

Source: In Bioorganic & Medicinal Chemistry 1 January 2025 117

A novel small molecule phagocytosis inhibitor, KB‐208, ameliorates ITP in mouse models with similar efficacy as IVIG.

Authors: Loriamini, Melika^1,2 (AUTHOR), Lewis‐Bakker, Melissa M.³ (AUTHOR), Binnington, Beth² (AUTHOR), Kotra, Lakshmi P.^3,4 (AUTHOR) lakshmi.kotra@uhn.ca, Branch, Donald R.^1,2,5 (AUTHOR) don.branch@utoronto.ca

Source: Transfusion. Dec2024, Vol. 64 Issue 12, p2233-2240. 8p.

Subject Terms: *DRUG discovery, *DRUG efficacy, *IDIOPATHIC thrombocytopenic purpura, *SMALL molecules, *BLOOD transfusion

Small Molecule Drugs That Inhibit Phagocytosis.

Authors: Loriamini, Melika^1,2 (AUTHOR), Lewis-Bakker, Melissa M.³ (AUTHOR), Frias Boligan, Kayluz¹ (AUTHOR), Wang, Siming³ (AUTHOR), Holton, Mairead B.¹ (AUTHOR), Kotra, Lakshmi P.^3,4 (AUTHOR) p.kotra@utoronto.ca, Branch, Donald R.^1,2,5,6 (AUTHOR) p.kotra@utoronto.ca

Source: Molecules. Jan2023, Vol. 28 Issue 2, p757. 15p.

Subject Terms: *SMALL molecules, *PHAGOCYTOSIS, *CHEMICAL libraries, *PHAGOCYTIC function tests, *DRUG discovery

062 - DELTA-9-TETRAHYDROCANNABINOL MODIFIES THE TRANCRIPTOMES OF JOINT-INNERVATING DORSAL ROOT GANGLIA CELLS AND THE SYSTEMIC METABOLOME IN MOUSE MODELS OF OA.

Authors: Maglaviceanu, Anca, Rockel, Jason S., Filippini, Helena F., Wasilewski, Ewa, Lewis-Bakker, Melissa M., Vohra, Shabana, Hueniken, Katrina, Espin-Garcia, Osvaldo, Pastrello, Chiara, Potla, Pratibha, Deng, Yangqing, Santos, Keemo Delos, Lively, Starlee, Looby, Nikita, Garcia, Johana, Tahiri, Evan P., Ravarian, Behdad, Wang, Jian, Fehlings, Michael, Gandhi, Rajiv

Source: Osteoarthritis & Cartilage; 2025 Supplement, Vol. 33, pS50-S51, 2p

047 - ORAL GAVAGE OF DELTA-9-TETRAHYDROCANNABINOL PROVIDES PAIN AND DISEASE MODIFICATION IN MOUSE MODELS OF KNEE OSTEOARTHRITIS

Authors: Maglaviceanu, Anca, Rockel, Jason S., Filippini, Helena F., Wasilewski, Ewa, Lewis-Bakker, Melissa M., Pastrello, Chiara, Gabrial, Sarah, Rossomacha, Evgeny, Garcia, Johana, Tahiri, Evan P., Mahomed, Nizar N., Jurisica, Igor, Leroux, Timothy, Clarke, Hance, Bonin, Robert P., Kotra, Lakshmi P., Kapoor, Mohit

Source: In Osteoarthritis and Cartilage April 2024 32 Supplement 1:S39-S39

3040 – DRUG DISCOVERY FOR INHIBITORS OF PHAGOCYTOSIS FOR USE IN IMMUNE CYTOPENIAS

Authors: Branch, Donald, Loriamini, Melika, Lewis-Bakker, Melissa, Boligan, Kayluz Frias, Kotra, Lakshmi

Source: In Experimental Hematology 2022 111 Supplement:S64-S65

Extractions of Medical Cannabis Cultivars and the Role of Decarboxylation in Optimal Receptor Responses.

Authors: Lewis-Bakker, Melissa M., Yang, Yi, Vyawahare, Rupali, Kotra, Lakshmi P.

Source: Cannabis & Cannabinoid Research; Sep2019, Vol. 4 Issue 3, p183-194, 12p

Bioactive Chemical Composition of Cannabis Extracts and Cannabinoid Receptors.

Authors: Yang, Yi, Vyawahare, Rupali, Lewis-Bakker, Melissa, Clarke, Hance A., Wong, Albert H. C., Kotra, Lakshmi P., Busardò, Francesco Paolo

Source: Molecules; Aug2020, Vol. 25 Issue 15, p3466, 1p

Subject Terms: CANNABINOID receptors, MEDICAL marijuana, PARTIAL least squares regression, SUPERCRITICAL carbon dioxide, ARCHAEOLOGICAL human remains

This result is not displayed to guests.
Login for full access.