Novel epigenetic clock for fetal brain development predicts prenatal age for cellular stem cell models and derived neurons

Authors: Leonard C. Steg, Gemma L. Shireby, Jennifer Imm, Jonathan P. Davies, Alice Franklin, Robert Flynn, Seema C. Namboori, Akshay Bhinge, Aaron R. Jeffries, Joe Burrage, Grant W. A. Neilson, Emma M. Walker, Leo W. Perfect, Jack Price, Grainne McAlonan, Deepak P. Srivastava, Nicholas J. Bray, Emma L. Cope, Kimberley M. Jones, Nicholas D. Allen, Ehsan Pishva, Emma L. Dempster, Katie Lunnon, Jonathan Mill, Eilis Hannon

Source: Molecular Brain, Vol 14, Iss 1, Pp 1-11 (2021)

Subject Terms: Epigenetic clock, DNA methylation, Fetal, Neurodevelopment, Induced pluripotent stem cells, iPSC-derived neurons, Neurology. Diseases of the nervous system, RC346-429

File Description: electronic resource

Relation: https://doaj.org/toc/1756-6606

Access URL: https://doaj.org/article/18efbbb134be4d4aa4a20747dc35b350