Click chemistry functionalization of self‐assembling peptide hydrogels

Authors: Sharick, Joe T., Atieh, Angelina J., Gooch, Keith J., Leight, Jennifer L.

Source: Journal of biomedical materials research.Part A. 111(3):389-403

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100175820562.0x000001&indx=1&recIds=ETOCvdc_100175820562.0x000001

Oncogenic Functions of Alternatively Spliced MDM2-ALT2 Isoform in Retroperitoneal Liposarcoma.

Authors: de Faria, Fernanda Costas C., Khurshid, Safiya, Sarchet, Patricia, Tahara, Sayumi, Casadei, Lucia, Grignol, Valerie, Karna, Roma, Rentsch, Sydney, Sp, Nipin, Beane, Joal D., Mazzoccoli, Luciano, Montes, Matias, Nigita, Giovanni, Sharick, Joe T., Leight, Jennifer L., Calore, Federica, Chandler, Dawn S., Pollock, Raphael E.

Source: International Journal of Molecular Sciences; Dec2024, Vol. 25 Issue 24, p13516, 16p

Subject Terms: RETROPERITONEUM diseases, SARCOMA, LIPOSARCOMA, SURGICAL excision, CELL lines

Stromal PTEN Regulates Extracellular Matrix Organization in the Mammary Gland

Authors: Jones, Caitlin E., Hammer, Anisha M., Cho, YouJin, Sizemore, Gina M., Cukierman, Edna, Yee, Lisa D., Ghadiali, Samir N., Ostrowski, Michael C., Leight, Jennifer L.

Source: In Neoplasia January 2019 21(1):132-145

High-Throughput Three-Dimensional Hydrogel Cell Encapsulation Assay for Measuring Matrix Metalloproteinase Activity

Authors: Fakhouri, Abdulaziz S., Weist, Jessica L., Tomusko, Anthony R., Leight, Jennifer L.

Source: Assay and drug development technologies. 17(3):100-115

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100083621391.0x000001&indx=1&recIds=ETOCvdc_100083621391.0x000001

Work in Progress: Co-creation of Teaching Team Competencies and Values.

Authors: Leight, Jennifer L.¹, Hurtubise, Larry, Nocera, Tanya M.¹

Source: Proceedings of the ASEE Annual Conference & Exposition. 2024, p1-9. 9p.

Detection of proteolytic activity by covalent tethering of fluorogenic substrates in zymogram gels

Authors: Deshmukh, Ameya A, Weist, Jessica L, Leight, Jennifer L

Source: Biotechniques. 64(5):203-210

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100125683271.0x000001&indx=1&recIds=ETOCvdc_100125683271.0x000001

Multifunctional bioscaffolds for 3D culture of melanoma cells reveal increased MMP activity and migration with BRAF kinase inhibition

Authors: Leight, Jennifer L., Tokuda, Emi Y., Jones, Caitlin E., Lin, Austin J., Anseth, Kristi S.

Source: Proceedings of the National Academy of Sciences of the United States of America, 2015 Apr . 112(17), 5366-5371.

Access URL: https://www.jstor.org/stable/26462564

Modulation of matrix elasticity with PEG hydrogels to study melanoma drug responsiveness

Authors: Tokuda, Emi Y., Leight, Jennifer L., Anseth, Kristi S.

Source: In Biomaterials May 2014 35(14):4310-4318

Direct measurement of matrix metalloproteinase activity in 3D cellular microenvironments using a fluorogenic peptide substrate

Authors: Leight, Jennifer L., Alge, Daniel L., Maier, Andrew J., Anseth, Kristi S.

Source: In Biomaterials October 2013 34(30):7344-7352

In utero estrogenic endocrine disruption alters the stroma to increase extracellular matrix density and mammary gland stiffness

Authors: Wormsbaecher, Clarissa, Hindman, Andrea R., Avendano, Alex, Cortes-Medina, Marcos, Jones, Caitlin E., Bushman, Andrew, Onua, Lotanna, Kovalchin, Claire E., Murphy, Alina R., Helber, Hannah L., Shapiro, Ali, Voytovitch, Kyle, Kuang, Xingyan, Aguilar-Valenzuela, Renan, Leight, Jennifer L., Song, Jonathan W., Burd, Craig J.

Source: Breast cancer research. 22(1)

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100171990360.0x000001&indx=1&recIds=ETOCvdc_100171990360.0x000001

A 3D adrenocortical carcinoma tumor platform for preclinical modeling of drug response and matrix metalloproteinase activity.

Authors: Dedhia, Priya H., Sivakumar, Hemamylammal, Rodriguez, Marco A., Nairon, Kylie G., Zent, Joshua M., Zheng, Xuguang, Jones, Katie, Popova, Liudmila V., Leight, Jennifer L., Skardal, Aleksander

Source: Scientific Reports; 9/19/2023, Vol. 13 Issue 1, p1-12, 12p

Subject Terms: MATRIX metalloproteinases, CELL culture, PHYSIOLOGY, ANIMAL models in research, HUMAN biology, MICROFLUIDIC devices

Work in Progress: Co-creation of biomedical engineering teaching team competencies and values.

Authors: Leight, Jennifer L.¹, Hurtubise, Larry¹, Nocera, Tanya M.¹

Source: Proceedings of the ASEE Annual Conference & Exposition. 2023, p1-9. 9p.

Three dimensional models of dedifferentiated liposarcoma cell lines: scaffold-based and scaffold-free approaches.

Authors: Tahara, Sayumi, de Faria, Fernanda Costas C., Sarchet, Patricia, Calore, Federica, Sharick, Joe, Leight, Jennifer L., Casadei, Lucia, Pollock, Raphael E.

Source: Human Cell; May2023, Vol. 36 Issue 3, p1081-1089, 9p

Subject Terms: LIPOSARCOMA, CELL lines, CELL culture, WESTERN immunoblotting, EXTRACELLULAR matrix, SARCOMA

Demystifying the Effects of a Three‐Dimensional Microenvironment in Tissue Morphogenesis

Authors: Johnson, Kandice R. ^*, Leight, Jennifer L. ^*, Weaver, Valerie M.

Source: In Methods in Cell Biology 2007 83:547-583

Matrix compliance permits NF-κB activation to drive therapy resistance in breast cancer

Authors: Drain, Allison P., Zahir, Nastaran, Northey, Jason J., Zhang, Hui, Huang, Po-Jui, Maller, Ori, Lakins, Johnathon N., Yu, Xinmiao, Leight, Jennifer L., Alston-Mills, Brenda P.

Source: Journal of experimental medicine. 218(5):e20191360-e20191360

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCRN626499764&indx=1&recIds=ETOCRN626499764

Pten regulates collagen fibrillogenesis by fibroblasts through SPARC.

Authors: Jones, Caitlin E., Sharick, Joe T., Colbert, Sheila E., Shukla, Vasudha C., Zent, Joshua M., Ostrowski, Michael C., Ghadiali, Samir N., Sizemore, Steven T., Leight, Jennifer L.

Source: PLoS ONE; 2/3/2021, Vol. 16 Issue 2, p1-21, 21p

Subject Terms: COLLAGEN, MAMMARY glands, FIBROBLASTS, EXTRACELLULAR matrix, BREAST tumors, CANCER invasiveness

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Synthesis of Microgel Sensors for Spatial and Temporal Monitoring of Protease Activity

Authors: Shin, Della S., Tokuda, Emi Y., Leight, Jennifer L., Miksch, Connor E., Brown, Tobin E., Anseth, Kristi S.

Source: ACS Biomaterials Science & Engineering; 20240101, Issue: Preprints