Obesity-associated changes in molecular biology of primary breast cancer

Authors: Ha-Linh Nguyen, Tatjana Geukens, Marion Maetens, Samuel Aparicio, Ayse Bassez, Ake Borg, Jane Brock, Annegien Broeks, Carlos Caldas, Fatima Cardoso, Maxim De Schepper, Mauro Delorenzi, Caroline A. Drukker, Annuska M. Glas, Andrew R. Green, Edoardo Isnaldi, Jórunn Eyfjörð, Hazem Khout, Stian Knappskog, Savitri Krishnamurthy, Sunil R. Lakhani, Anita Langerod, John W. M. Martens, Amy E. McCart Reed, Leigh Murphy, Stefan Naulaerts, Serena Nik-Zainal, Ines Nevelsteen, Patrick Neven, Martine Piccart, Coralie Poncet, Kevin Punie, Colin Purdie, Emad A. Rakha, Andrea Richardson, Emiel Rutgers, Anne Vincent-Salomon, Peter T. Simpson, Marjanka K. Schmidt, Christos Sotiriou, Paul N. Span, Kiat Tee Benita Tan, Alastair Thompson, Stefania Tommasi, Karen Van Baelen, Marc Van de Vijver, Steven Van Laere, Laura van’t Veer, Giuseppe Viale, Alain Viari, Hanne Vos, Anke T. Witteveen, Hans Wildiers, Giuseppe Floris, Abhishek D. Garg, Ann Smeets, Diether Lambrechts, Elia Biganzoli, François Richard, Christine Desmedt

Source: Nature Communications, Vol 14, Iss 1, Pp 1-17 (2023)

Subject Terms: Science

File Description: electronic resource

Relation: https://doaj.org/toc/2041-1723

Access URL: https://doaj.org/article/449fce543ad84736bc9d60953aa2df60

Development and validation of a prognostic 15-gene signature for stratifying HER2+/ER+ breast cancer

Authors: Qian Liu, Shujun Huang, Danielle Desautels, Kirk J. McManus, Leigh Murphy, Pingzhao Hu

Source: Computational and Structural Biotechnology Journal, Vol 21, Iss , Pp 2940-2949 (2023)

Subject Terms: Breast cancer, Subtyping, Consensus clustering, Gene signature, Machine learning, Biotechnology, TP248.13-248.65

File Description: electronic resource

Relation: http://www.sciencedirect.com/science/article/pii/S2001037023001848; https://doaj.org/toc/2001-0370

Access URL: https://doaj.org/article/6158a5833f5544c2ae30439be64a9518

Data-driven identification of plasma metabolite clusters and metabolites of interest for potential detection of early-stage non-small cell lung cancer cases versus cancer-free controls

Authors: Julian O. Kim, Robert Balshaw, Connel Trevena, Shantanu Banerji, Leigh Murphy, David Dawe, Lawrence Tan, Sadeesh Srinathan, Gordon Buduhan, Biniam Kidane, Gefei Qing, Michael Domaratzki, Michel Aliani

Source: Cancer & Metabolism, Vol 10, Iss 1, Pp 1-13 (2022)

Subject Terms: Early-stage non-small cell lung cancer, Plasma metabolomics, Early detection, Non-targeted metabolomics, Neoplasms. Tumors. Oncology. Including cancer and carcinogens, RC254-282

File Description: electronic resource

Relation: https://doaj.org/toc/2049-3002

Access URL: https://doaj.org/article/de5caa2bb46646a385eb9236915ff104

Nuclear TIGAR mediates an epigenetic and metabolic autoregulatory loop via NRF2 in cancer therapeutic resistance

Authors: Hong Wang, Qianqian Wang, Guodi Cai, Zhijian Duan, Zoann Nugent, Jie Huang, Jianwei Zheng, Alexander D. Borowsky, Jian Jian Li, Peiqing Liu, Hsing-Jien Kung, Leigh Murphy, Hong-Wu Chen, Junjian Wang

Source: Acta Pharmaceutica Sinica B, Vol 12, Iss 4, Pp 1871-1884 (2022)

Subject Terms: TIGAR, NSD2, NRF2, Metabolism, Oxidative stress, Epigenetic reprogramming, Therapeutics. Pharmacology, RM1-950

File Description: electronic resource

Relation: http://www.sciencedirect.com/science/article/pii/S221138352100407X; https://doaj.org/toc/2211-3835

Access URL: https://doaj.org/article/538925d98d464283b8a69c88387e94f7

DNA methylation landscapes of 1538 breast cancers reveal a replication-linked clock, epigenomic instability and cis-regulation

Authors: Rajbir Nath Batra, Aviezer Lifshitz, Ana Tufegdzic Vidakovic, Suet-Feung Chin, Ankita Sati-Batra, Stephen-John Sammut, Elena Provenzano, H. Raza Ali, Ali Dariush, Alejandra Bruna, Leigh Murphy, Arnie Purushotham, Ian Ellis, Andrew Green, Francine E. Garrett-Bakelman, Chris Mason, Ari Melnick, Samuel A. J. R. Aparicio, Oscar M. Rueda, Amos Tanay, Carlos Caldas

Source: Nature Communications, Vol 12, Iss 1, Pp 1-13 (2021)

Subject Terms: Science

File Description: electronic resource

Relation: https://doaj.org/toc/2041-1723

Access URL: https://doaj.org/article/7832b4cd7ff242839e4e5e73265c879e

Computational Prediction of the Pathogenic Status of Cancer-Specific Somatic Variants

Authors: Nikta Feizi, Qian Liu, Leigh Murphy, Pingzhao Hu

Source: Frontiers in Genetics, Vol 12 (2022)

Subject Terms: somatic variants, computational classification, pathogenic status, breast cancer, survival analysis, Genetics, QH426-470

File Description: electronic resource

Relation: https://www.frontiersin.org/articles/10.3389/fgene.2021.805656/full; https://doaj.org/toc/1664-8021

Access URL: https://doaj.org/article/e61bdd07fdbd42879882b713492f4601

Comparative metabolomics studies of blood collected in streck and heparin tubes from lung cancer patients.

Authors: Erin Goldberg, Shiva Ievari-Shariati, Biniam Kidane, Julian Kim, Shantanu Banerji, Gefei Qing, Sadeesh Srinathan, Leigh Murphy, Michel Aliani

Source: PLoS ONE, Vol 16, Iss 4, p e0249648 (2021)

Subject Terms: Medicine, Science

File Description: electronic resource

Relation: https://doaj.org/toc/1932-6203

Access URL: https://doaj.org/article/c05025e0a90e4ff698bd8ef5500bdcc6

Claudin 1 Is Highly Upregulated by PKC in MCF7 Human Breast Cancer Cells and Correlates Positively with PKCε in Patient Biopsies

Authors: Anne A. Blanchard, Xiuli Ma, Nan Wang, Sabine Hombach-Klonisch, Carla Penner, Arzu Ozturk, Thomas Klonisch, Marshall Pitz, Leigh Murphy, Etienne Leygue, Yvonne Myal

Source: Translational Oncology, Vol 12, Iss 3, Pp 561-575 (2019)

Subject Terms: Neoplasms. Tumors. Oncology. Including cancer and carcinogens, RC254-282

File Description: electronic resource

Relation: http://www.sciencedirect.com/science/article/pii/S1936523318305758; https://doaj.org/toc/1936-5233

Access URL: https://doaj.org/article/d749761141ef4a0da9a809529ccffee2

Genes and functions from breast cancer signatures

Authors: Shujun Huang, Leigh Murphy, Wayne Xu

Source: BMC Cancer, Vol 18, Iss 1, Pp 1-15 (2018)

Subject Terms: Breast cancer, Multi-gene signature, Common gene, Common function, Neoplasms. Tumors. Oncology. Including cancer and carcinogens, RC254-282

File Description: electronic resource

Relation: http://link.springer.com/article/10.1186/s12885-018-4388-4; https://doaj.org/toc/1471-2407

Access URL: https://doaj.org/article/5f4cd1b41dde4dd69cb75cf753bc3597

The exploration of contrasting pathways in Triple Negative Breast Cancer (TNBC)

Authors: Shavira Narrandes, Shujun Huang, Leigh Murphy, Wayne Xu

Source: BMC Cancer, Vol 18, Iss 1, Pp 1-8 (2018)

Subject Terms: Triple Negative Breast Cancer, Pathway, Drug target, FOXM1, PPARα, Neoplasms. Tumors. Oncology. Including cancer and carcinogens, RC254-282

File Description: electronic resource

Relation: http://link.springer.com/article/10.1186/s12885-017-3939-4; https://doaj.org/toc/1471-2407

Access URL: https://doaj.org/article/9cab81983fba4662a044e16077ddfefb

The somatic mutation profiles of 2,433 breast cancers refine their genomic and transcriptomic landscapes

Authors: Bernard Pereira, Suet-Feung Chin, Oscar M. Rueda, Hans-Kristian Moen Vollan, Elena Provenzano, Helen A. Bardwell, Michelle Pugh, Linda Jones, Roslin Russell, Stephen-John Sammut, Dana W. Y. Tsui, Bin Liu, Sarah-Jane Dawson, Jean Abraham, Helen Northen, John F. Peden, Abhik Mukherjee, Gulisa Turashvili, Andrew R. Green, Steve McKinney, Arusha Oloumi, Sohrab Shah, Nitzan Rosenfeld, Leigh Murphy, David R. Bentley, Ian O. Ellis, Arnie Purushotham, Sarah E. Pinder, Anne-Lise Børresen-Dale, Helena M. Earl, Paul D. Pharoah, Mark T. Ross, Samuel Aparicio, Carlos Caldas

Source: Nature Communications, Vol 7, Iss 1, Pp 1-16 (2016)

Subject Terms: Science

File Description: electronic resource

Relation: https://doaj.org/toc/2041-1723

Access URL: https://doaj.org/article/6d0c8d9a2f0d4a168b5aa700c8e0ffba

Erratum: The somatic mutation profiles of 2,433 breast cancers refine their genomic and transcriptomic landscapes

Authors: Bernard Pereira, Suet-Feung Chin, Oscar M. Rueda, Hans-Kristian Moen Vollan, Elena Provenzano, Helen A. Bardwell, Michelle Pugh, Linda Jones, Roslin Russell, Stephen-John Sammut, Dana W. Y. Tsui, Bin Liu, Sarah-Jane Dawson, Jean Abraham, Helen Northen, John F. Peden, Abhik Mukherjee, Gulisa Turashvili, Andrew R. Green, Steve McKinney, Arusha Oloumi, Sohrab Shah, Nitzan Rosenfeld, Leigh Murphy, David R. Bentley, Ian O. Ellis, Arnie Purushotham, Sarah E. Pinder, Anne-Lise Børresen-Dale, Helena M. Earl, Paul D. Pharoah, Mark T. Ross, Samuel Aparicio, Carlos Caldas

Source: Nature Communications, Vol 7, Iss 1, Pp 1-1 (2016)

Subject Terms: Science

File Description: electronic resource

Relation: https://doaj.org/toc/2041-1723

Access URL: https://doaj.org/article/fc891aa190c54d0ab21e7f9f06b96eb9

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Estrogen receptors inhibit Smad3 transcriptional activity through Ap-1 transcription factors.

Authors: Tracy Cherlet, Leigh Murphy

Source: Molecular & Cellular Biochemistry; Dec2007, Vol. 306 Issue 1/2, p33-42, 10p

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How Do We Teach Them to Read If They Can’t Pay Attention? Change in Literacy Teaching Practice through Collaborative Learning

Authors: Shelley Leigh Murphy

Source: Language and Literacy: A Canadian Educational e-journal, Vol 17, Iss 1, Pp 83-105 (2015)

Subject Terms: literacy teaching, professional development, adhd, collaborative learning, elementary teaching, Theory and practice of education, LB5-3640, Language and Literature

File Description: electronic resource

Relation: https://journals.library.ualberta.ca/langandlit/index.php/langandlit/article/view/22177; https://doaj.org/toc/1496-0974

Access URL: https://doaj.org/article/043e2c9283704fe09d1a1475abf7ae6a