Senescence induction dictates response to chemo- and immunotherapy in preclinical models of ovarian cancer

Authors: Paffenholz, Stella V., Salvagno, Camilla, Ho, Yu-Jui, Limjoco, Matthew, Baslan, Timour, Tian, Sha, Kulick, Amanda, de Stanchina, Elisa, Wilkinson, John E., Barriga, Francisco M., Zamarin, Dmitriy, Cubillos-Ruiz, Juan R., Leibold, Josef, Lowe, Scott W.

Source: Proceedings of the National Academy of Sciences of the United States of America, 2022 Feb 01. 119(5), 1-11.

Access URL: https://www.jstor.org/stable/27117752

Senescence-Induced Vascular Remodeling Creates Therapeutic Vulnerabilities in Pancreas Cancer

Authors: Ruscetti, Marcus, Morris, John P., IV, Mezzadra, Riccardo, Russell, James, Leibold, Josef, Romesser, Paul B., Simon, Janelle, Kulick, Amanda, Ho, Yu-jui, Fennell, Myles, Li, Jinyang, Norgard, Robert J., Wilkinson, John E., Alonso-Curbelo, Direna, Sridharan, Ramya, Heller, Daniel A., de Stanchina, Elisa, Stanger, Ben Z., Sherr, Charles J., Lowe, Scott W.

Source: In Cell 16 April 2020 181(2):424-441

The Oncogenic Action of NRF2 Depends on De-glycation by Fructosamine-3-Kinase

Authors: Sanghvi, Viraj R., Leibold, Josef, Mina, Marco, Mohan, Prathibha, Berishaj, Marjan, Li, Zhuoning, Miele, Matthew M., Lailler, Nathalie, Zhao, Chunying, de Stanchina, Elisa, Viale, Agnes, Akkari, Leila, Lowe, Scott W., Ciriello, Giovanni, Hendrickson, Ronald C., Wendel, Hans-Guido

Source: In Cell 8 August 2019 178(4):807-819

NK cell–mediated cytotoxicity contributes to tumor control by a cytostatic drug combination

Authors: Ruscetti, Marcus, Leibold, Josef, Bott, Matthew J., Fennell, Myles, Kulick, Amanda, Salgado, Nelson R., Chen, Chi-Chao, Ho, Yu-jui, Sanchez-Rivera, Francisco J., Feucht, Judith, Baslan, Timour, Tian, Sha, Chen, Hsuan-An, Romesser, Paul B., Poirier, John T., Rudin, Charles M., de Stanchina, Elisa, Manchado, Eusebio, Sherr, Charles J., Lowe, Scott W.

Source: Science, 2018 Dec . 362(6421), 1416-1422.

Access URL: https://www.jstor.org/stable/26569439

Immunotherapy in ovarian cancer: spatial functional genomics to unravel resistance mechanisms.

Authors: Rausch, Martina, Bartels, Karlotta, Leibold, Josef

Source: Signal Transduction & Targeted Therapy; 1/22/2025, Vol. 10 Issue 1, p1-3, 3p

Calibration of CAR activation potential directs alternative T cell fates and therapeutic potency

Authors: Feucht, Judith, Sun, Jie, Eyquem, Justin, Ho, Yu-Jui, Zhao, Zeguo, Leibold, Josef, Dobrin, Anton, Cabriolu, Annalisa, Hamieh, Mohamad, Sadelain, Michel

Source: Nature medicine. 25(1):82-88

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100102162117.0x000001&indx=1&recIds=ETOCvdc_100102162117.0x000001

Induction of Oxidative Stress Through Inhibition of Thioredoxin Reductase 1 Is an Effective Therapeutic Approach for Hepatocellular Carcinoma

Authors: Lee, Derek, Xu, Iris Ming‐Jing, Chiu, David Kung‐Chun, Leibold, Josef, Tse, Aki Pui‐Wah, Bao, Macus Hao‐Ran, Yuen, Vincent Wai‐Hin, Chan, Cerise Yuen‐Ki, Lai, Robin Kit‐Ho, Chin, Don Wai‐Ching, Chan, Daniel For‐Fan, Cheung, Tan‐To, Chok, Siu‐Ho, Wong, Chun‐Ming, Lowe, Scott W., Ng, Irene Oi‐Lin, Wong, Carmen Chak‐Lui

Source: Hepatology. 69(4):1768-1786

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100083096122.0x000001&indx=1&recIds=ETOCvdc_100083096122.0x000001

Senescence-Induced Vascular Remodeling Creates Therapeutic Vulnerabilities in Pancreas Cancer

Authors: Ruscetti, Marcus, Morris, John P., Mezzadra, Riccardo, Russell, James, Leibold, Josef, Romesser, Paul B., Simon, Janelle, Kulick, Amanda, Ho, Yu-jui, Fennell, Myles, Li, Jinyang, Norgard, Robert J., Wilkinson, John E., Alonso-Curbelo, Direna, Sridharan, Ramya, Heller, Daniel A., de Stanchina, Elisa, Stanger, Ben Z., Sherr, Charles J., Lowe, Scott W.

Source: Cell. 184(18):4838-4839

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100164564765.0x000001&indx=1&recIds=ETOCvdc_100164564765.0x000001

Base editing sensor libraries for high-throughput engineering and functional analysis of cancer-associated single nucleotide variants.

Authors: Sánchez-Rivera, Francisco J., Diaz, Bianca J., Kastenhuber, Edward R., Schmidt, Henri, Katti, Alyna, Kennedy, Margaret, Tem, Vincent, Ho, Yu-Jui, Leibold, Josef, Paffenholz, Stella V., Barriga, Francisco M., Chu, Kevan, Goswami, Sukanya, Wuest, Alexandra N., Simon, Janelle M., Tsanov, Kaloyan M., Chakravarty, Debyani, Zhang, Hongxin, Leslie, Christina S., Lowe, Scott W.

Source: Nature Biotechnology; Jun2022, Vol. 40 Issue 6, p862-873, 12p

Publisher Correction: Calibration of CAR activation potential directs alternative T cell fates and therapeutic potency

Authors: Feucht, Judith, Sun, Jie, Eyquem, Justin, Ho, Yu-Jui, Zhao, Zeguo, Leibold, Josef, Dobrin, Anton, Cabriolu, Annalisa, Hamieh, Mohamad, Sadelain, Michel

Source: Nature medicine. 25(3):530-530

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100127961199.0x000001&indx=1&recIds=ETOCvdc_100127961199.0x000001

Senolytic CAR T cells reverse senescence-associated pathologies.

Authors: Amor, Corina, Feucht, Judith, Leibold, Josef, Ho, Yu-Jui, Zhu, Changyu, Alonso-Curbelo, Direna, Mansilla-Soto, Jorge, Boyer, Jacob A., Li, Xiang, Giavridis, Theodoros, Kulick, Amanda, Houlihan, Shauna, Peerschke, Ellinor, Friedman, Scott L., Ponomarev, Vladimir, Piersigilli, Alessandra, Sadelain, Michel, Lowe, Scott W.

Source: Nature; 7/2/2020, Vol. 583 Issue 7814, p127-132, 6p, 12 Color Photographs, 1 Diagram, 2 Graphs

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Author Correction: Senolytic CAR T cells reverse senescence-associated pathologies.

Authors: Amor, Corina, Feucht, Judith, Leibold, Josef, Ho, Yu-Jui, Zhu, Changyu, Alonso-Curbelo, Direna, Mansilla-Soto, Jorge, Boyer, Jacob A., Li, Xiang, Giavridis, Theodoros, Kulick, Amanda, Houlihan, Shauna, Peerschke, Ellinor, Friedman, Scott L., Ponomarev, Vladimir, Piersigilli, Alessandra, Sadelain, Michel, Lowe, Scott W.

Source: Nature; Mar2024, Vol. 627 Issue 8004, pE9-E9, 1p

Calibrated CAR Activation Potential Directs Alternative T Cell Fates and Therapeutic Potency

Authors: Feucht, Judith ^*, Sun, Jie ^*, Eyquem, Justin ^*, Ho, Yu-Jui ^*, Zhao, Zeguo ^*, Leibold, Josef ^*, Dobrin, Anton ^*, Cabriolu, Annalisa ^*, Hamieh, Mohamad ^*, Sadelain, Michel

Source: In Blood 29 November 2018 132 Supplement 1:1412-1412

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Stocherkahnfahrer mit Ikterus. (German)

Alternate Title: Punt-driver with jaundice. (English)

Authors: Leibold, Josef, Fusco, Stefano, Feucht, Judith, Artunc, Ferruh, Malek, Nisar, Bitzer, Michael

Source: DMW: Deutsche Medizinische Wochenschrift; 2014, Vol. 139 Issue 1, p1-31, 31p

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