Alleviating misclassified germline variants in underrepresented populations: A strategy using popmax

Authors: Lee, Ning Yuan, Hum, Melissa, Wong, Matthew, Ong, Pei-Yi, Lee, Soo-Chin, Lee, Ann S.G.

Source: In Genetics in Medicine June 2024 26(6)

A glycolytic metabolite bypasses “two-hit” tumor suppression by BRCA2

Authors: Kong, Li Ren, Gupta, Komal, Wu, Andy Jialun, Perera, David, Ivanyi-Nagy, Roland, Ahmed, Syed Moiz, Tan, Tuan Zea, Tan, Shawn Lu-Wen, Fuddin, Alessandra, Sundaramoorthy, Elayanambi, Goh, Grace Shiqing, Wong, Regina Tong Xin, Costa, Ana S.H., Oddy, Callum, Wong, Hannan, Patro, C. Pawan K., Kho, Yun Suen, Huang, Xiao Zi, Choo, Joan, Shehata, Mona, Lee, Soo Chin, Goh, Boon Cher, Frezza, Christian, Pitt, Jason J., Venkitaraman, Ashok R.

Source: In Cell 25 April 2024 187(9):2269-2287

IFI16-dependent STING signaling is a crucial regulator of anti-HER2 immune response in HER2+ breast cancer

Authors: Ong, Li-Teng, Lee, Wee Chyan, Ma, Shijun, Oguz, Gokce, Niu, Zhitong, Bao, Yi, Yusuf, Mubaraka, Lee, Puay Leng, Goh, Jian Yuan, Wang, Panpan, Yong, Kylie Su Mei, Chen, Qingfeng, Wang, Wenyu, Ramasamy, Adaikalavan, Hoon, Dave S. B., Ditzel, Henrik J., Tan, Ern Yu, Lee, Soo Chin, Yu, Qiang

Source: Proceedings of the National Academy of Sciences of the United States of America, 2022 Aug 01. 119(31), 1-12.

Access URL: https://www.jstor.org/stable/27172157

Phase II study of trifluridine/tipiracil in metastatic breast cancers with or without prior exposure to fluoropyrimidines

Authors: Lim, Joline S.J., Ow, Samuel G.W., Wong, Andrea L.A., Lee, Matilda X.W., Chan, Gloria H.J., Low, Jia Li, Sundar, Raghav, Choo, Joan R.E., Chong, Wan Qin, Ang, Yvonne L.E., Tai, Bee Choo, Lee, Soo Chin

Source: In European Journal of Cancer November 2023 193

Booster doses of COVID-19 vaccines for patients with haematological and solid cancer: a systematic review and individual patient data meta-analysis

Authors: Mai, Aaron Shengting, Lee, Ainsley Ryan Yan Bin, Tay, Ryan Yong Kiat, Shapiro, Lauren, Thakkar, Astha, Halmos, Balazs, Grinshpun, Albert, Herishanu, Yair, Benjamini, Ohad, Tadmor, Tamar, Shroff, Rachna T., LaFleur, Bonnie J., Bhattacharya, Deepta, Peng, Siyu, Tey, Jeremy, Lee, Soo Chin, Chai, Louis Yi Ann, Soon, Yu Yang, Sundar, Raghav, Lee, Matilda Xinwei

Source: In European Journal of Cancer September 2022 172:65-75

Adjuvant Atezolizumab for Early Triple-Negative Breast Cancer: The ALEXANDRA/IMpassion030 Randomized Clinical Trial.

Authors: Ignatiadis, Michail, Bailey, Andrew, McArthur, Heather, El-abed, Sarra, de Azambuja, Evandro, Metzger, Otto, Chui, Stephen Y., Dieterich, Max, Perretti, Thomas, Shearer-Kang, Esther, Molinero, Luciana, Steger, Günther G., Jassem, Jacek, Lee, Soo Chin, Higgins, Michaela, Zarba, Jose, Schmidt, Marcus, Gomez, Henry, Guerrero Zotano, Angel, Moscetti, Luca

Source: JAMA: Journal of the American Medical Association; 4/1/2025, Vol. 333 Issue 13, p1150-1160, 11p

Safety and feasibility of concomitant scalp cooling and limb cryocompression to prevent paclitaxel-induced alopecia and neuropathy.

Authors: Bandla, Aishwarya, Wong, Rachel, Santhanakrishnan, Priyadharshini, Magarajah, Gayathiri, Yee, Yang En, Ng, Wei Yen, Ow, Samuel, Chan, Gloria, Choo, Joan, Lim, Siew Eng, Wong, Andrea, Vijayan, Joy, Paxman, Richard, Lee, Yee Mei, Hui, Fu, Hairom, Zarinah, Ang, Emily, Loprinzi, Charles, Thakor, Nitish, Lee, Soo Chin

Source: Supportive Care in Cancer; Mar2025, Vol. 33 Issue 3, p1-9, 9p

Clinical best practices in optimal monitoring, early diagnosis, and effective management of antibody–drug conjugate-induced interstitial lung disease or pneumonitis: a multidisciplinary team approach in Singapore

Authors: Yong, Wei Peng, Teo, Felicia SW, Teo, Lynette LS, Ng, Matthew CH, Tan, Tira J., Low, Su Ying, Wong, Karmen, Ang, Peter, Choo, Su Pin, Lee, Kim Hua, Lee, Soo Chin

Source: Expert opinion on drug metabolism and toxicology. 18(12):805-815

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100182440961.0x000001&indx=1&recIds=ETOCvdc_100182440961.0x000001

Extracellular vesicles, the cornerstone of next-generation cancer diagnosis?

Authors: Weng, Jiayi, Xiang, Xiaoqiang, Ding, Lingwen, Wong, Andrea Li-Ann, Zeng, Qi, Sethi, Gautam, Wang, Lingzhi ^*, Lee, Soo Chin ^*, Goh, Boon Cher ^*

Source: In Seminars in Cancer Biology September 2021 74:105-120

Identifying Novel Susceptibility Genes for Colorectal Cancer Risk From a Transcriptome-Wide Association Study of 125,478 Subjects

Authors: Guo, Xingyi, Lin, Weiqiang, Wen, Wanqing, Huyghe, Jeroen, Bien, Stephanie, Cai, Qiuyin, Harrison, Tabitha, Chen, Zhishan, Qu, Conghui, Bao, Jiandong, Long, Jirong, Yuan, Yuan, Wang, Fangqin, Bai, Mengqiu, Abecasis, Goncalo R., Albanes, Demetrius, Berndt, Sonja I., Bézieau, Stéphane, Bishop, D. Timothy, Brenner, Hermann, Buch, Stephan, Burnett-Hartman, Andrea, Campbell, Peter T., Castellví-Bel, Sergi, Chan, Andrew T., Chang-Claude, Jenny, Chanock, Stephen J., Cho, Sang Hee, Conti, David V., Chapelle, Albert de la, Feskens, Edith J.M., Gallinger, Steven J., Giles, Graham G., Goodman, Phyllis J., Gsur, Andrea, Guinter, Mark, Gunter, Marc J., Hampe, Jochen, Hampel, Heather, Hayes, Richard B., Hoffmeister, Michael, Kampman, Ellen, Kang, Hyun Min, Keku, Temitope O., Kim, Hyeong Rok, Le Marchand, Loic, Lee, Soo Chin, Li, Christopher I., Li, Li, Lindblom, Annika, Lindor, Noralane, Milne, Roger L., Moreno, Victor, Murphy, Neil, Newcomb, Polly A., Nickerson, Deborah A., Offit, Kenneth, Pearlman, Rachel, Pharoah, Paul D.P., Platz, Elizabeth A., Potter, John D., Rennert, Gad, Sakoda, Lori C., Schafmayer, Clemens, Schmit, Stephanie L., Schoen, Robert E., Schumacher, Fredrick R., Slattery, Martha L., Su, Yu-Ru, Tangen, Catherine M., Ulrich, Cornelia M., van Duijnhoven, Franzel J.B., Van Guelpen, Bethany, Visvanathan, Kala, Vodicka, Pavel, Vodickova, Ludmila, Vymetalkova, Veronika, Wang, Xiaoliang, White, Emily, Wolk, Alicja, Woods, Michael O., Casey, Graham, Hsu, Li, Jenkins, Mark A., Gruber, Stephen B., Peters, Ulrike, Zheng, Wei

Source: In Gastroenterology March 2021 160(4):1164-1178

Investigation into the origins of an ancient BRCA1 founder mutation identified among Chinese families in Singapore

Authors: Shaw, Tarryn, Chan, Sock Hoai, Teo, Jing Xian, Chong, Siao Ting, Li, Shao‐Tzu, Courtney, Eliza, Ishak, Diana, Sankar, Haresh, Ang, Zoe Li Ting, Chiang, Jianbang, Loh, Marie, Zhou, Li, Lee, Soo Chin, Yeh, Hui‐Yuan, Kolinjivadi, Arun Mouli, Lim, Weng Khong, Ngeow, Joanne

Source: International journal of cancer. 148(3):637-645

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100116450675.0x000001&indx=1&recIds=ETOCvdc_100116450675.0x000001

Scalp cooling therapy for chemotherapy-induced hair loss in patients with breast or gynecological cancers—an Asian tertiary institution experience.

Authors: Lee, Victor Guan Hui, Loh, Jerold, Hui, Fu, Sundar, Raghav, Tan, Belinda, Lee, Moy Chong, Lin, Hui Ying, Ong, Lay Ching, Visvanadan, Nisha, Ow, Samuel Guan Wei, Wong, Andrea Li Ann, Chan, Gloria Hui Jia, Lim, Siew Eng, Lim, Yi Wan, Tan, David Shao Peng, Ang, Yvonne, Choo, Joan, Lee, Matilda Xin Wei, Ngoi, Natalie Yan Li, Lee, Soo Chin

Source: Supportive Care in Cancer; Nov2024, Vol. 32 Issue 11, p1-7, 7p

Improving medication adherence with adjuvant aromatase inhibitor in women with breast cancer: A randomised controlled trial to evaluate the effect of short message service (SMS) reminder

Authors: Tan, Eng Hooi, Wong, Andrea Li Ann, Tan, Chuan Chien, Wong, Patrick, Tan, Sing Huang, Ang, Li En Yvonne, Lim, Siew Eng, Chong, Wan Qin, Ho, Jingshan, Lee, Soo Chin, Tai, Bee Choo

Source: In The Breast October 2020 53:77-84

Pertuzumab, trastuzumab, and docetaxel for HER2-positive metastatic breast cancer (CLEOPATRA): end-of-study results from a double-blind, randomised, placebo-controlled, phase 3 study

Authors: Agajanian, Richy, Ahmad, Rizvana, Aktas, Bahriye, Alencar, Victor Hugo, Amadori, Dino, Andrade, Jurandyr, André Franke, Fábio, Angiolini, Catia, Aogi, Kenjiro, Armor, Jess, Arpornwirat, Wichit, Assersohn, Laura, Audeh, William, Aulitzky, Walter, Azevedo, Sergio, Bartoli, Maria Alejandra, Batista Lopez, Norberto, Bianconi, María, Biganzoli, Laura, Birhiray, Ruemu, Bitina, Marianna, Blachy, Ron, Blackwell, Kimberly, Blanchard, Rita, Blanchet, Paulette, Boiangiu, Ion, Bower, Barbara, Brezden-Masley, Christine, Brufsky, Adam, Budde, Leanne, Caguioa, Priscilla, Calvo, Lourdes, Campone, Mario, Carroll, Robert R., Castro, Hugo, Chan, Valorie, Charu, Veena, Cinieri, Saverio, Clemens, Michael, Conejo, Emilio Alba, Côrtes, Eduardo, Coudert, Bruno, Cronemberger, Eduardo, Cubero, Daniel, Dakhil, Shaker, Daniel, Brooke, Davidson, Neville, De Fatima Gaui, Maria, De La Cruz, Susana, Del Pilar, Maria, Delgado, Gilson, Ellerton, John A., Estuardo, Cesar, Fehrenbacher, Louis, Ferrero, Jean-Marc, Flynn, Patrick J., Foszczynska-Kloda, Malgorzata, Franco, Sandra, Fujii, Hirofumi, Gallagher, Chris, Gamucci, Teresa, Giacomi, Nora, Gil I Gil, Miguel, Gonzalez Martin, Antonio, Gorbunova, Vera, Gotovkin, Eugeny, Green, Nathan, Grincuka, Elza, Grischke, Eva-Maria, Hansen, Vincent, Hargis, Jeffrey, Hauschild, Maik, Hegg, Roberto, Hendricks, Carolyn, Hermann, Robert, Hoff, Paulo, Horiguchi, Jun, Hornedo Muguiro, Javier, Iacobelli, Stefano, Inoue, Kenichi, Ismael, Gustavo, Itoh, Yoshinori, Iwata, Dr Hiroji, Jendiroba, Davi, Jochim, Rosa, Jones, Alison, Just, Marianne, Kallab, Andre, Karwal, Mark, Kashiwaba, Masahiro, Kato, Giraldo, Kaufman, Peter A., Kellokumpu-Lehtinen, Pirkko, Kirsch, Andreas, Kiselev, Igor, Klein, Paula, Kohno, Norio, Kopp, Mikhail, Kostovska-Maneva, Liljana, Kotliar, Mauricio, Kudaba, Iveta, Kümmel, Sherko, Kuroi, Katsumasa, Lacava, Juan, Latini, Luciano, Lee, Soo Chin, Lichinitser, Mikhail, Lobo, Christopher, Maintz, Christoph, Maneecahvakajorn, Jedzada, Marmé, Alexander, Martinez, Gloria, Masuda, Norikazu, Matwiejuk, Mario, Merculov, Vladimir, Michaelson, Richard, Miguel, Luis, Monroy, Hernandez, Montemurro, Filippo, Morales, Serafin, Moura, Rodrigo, Mueller, Volkmar, Mulatero, Clive, Nakagami, Kazuhiko, Nakayama, Takahiro, Neidhart, Jeff, Nguyen, An, Nishimura, Reiki, Ogata, Haruki, O'reilly, Susan, O'rourke, Timothy, Otero Reye, Douglas, Ouyang, Xuenong, Patel, Ravi, Patel, Taral, Pedrini, Jose Luiz, Pereira, Rodrigo, Perez, Alejandra, Peterson, Carol, Pienkowski, Tadeusz, Pinczowski, Helio, Polikoff, Jonathan, Polkowski, Wojciech, Price, Paola Edith, Prill, Sue, Priou, Frank, Purkalne, Gunta, Pyrhoenen, Seppo, Quackenbush, Robert, Rai, Yoshiaki, Ribelles, Nuria, Ro, Jungsil, Robinson, Anne, Robles, Robert, Rodriguez, Gladys, Roman, Laslo, Saji, Shigehira, Sanchez-Rovira, Pedro, Sato, Nobuaki, Schmidt, Marcus, Schumacher, Claudia, Senecal, Frank, Sharma, Priyanka, Shen, Zhenzhou, Shirinkin, Vadim, Simoncini, Edda, Sirisinha, Thitiya, Smith, Raymond, Sohn, Joo-Hyuk, Soldic, Zeljko, Soria, Tania, Spicer, Darcy, Srimuninnimit, Vichien, Sriuranpong, Virote, Staroslawska, Elzbieta, Stefanovski, Petar, Sunpaweravong, Patrapim, Taguchi, Julie, Takeda, Koji, Tellez-Trevilla, Gabriel, Thomas, Randall, Thomssen, Christoph, Toache, Zetina, Tokuda, Yutaka, Tomczak, Piotr, Tosello, Celia, Tsugawa, Koichiro, Tudtud, Dennis, Ueno, Takayuki, Van Eyll, Brigitte, Varela, Mirta, Vasev, Nikola, Vrbanec, Damir, Wang, Xiaojia, Wang, Liwei, Watanabe, Junichiro, Waterhouse, David, Wesenberg, Birgitta, Wheatley, Duncan, Wong, Zee Wan, Yadav, Sanjay, Yardley, Denise, Yau, Tsz-Kok, Yeo, Winnie, Ying, Cheng, Youn Oh, Do, Swain, Sandra M ^*, Miles, David, Kim, Sung-Bae, Im, Young-Hyuck, Im, Seock-Ah, Semiglazov, Vladimir, Ciruelos, Eva, Schneeweiss, Andreas, Loi, Sherene, Monturus, Estefanía, Clark, Emma, Knott, Adam, Restuccia, Eleonora, Benyunes, Mark C, Cortés, Javier

Source: In The Lancet Oncology April 2020 21(4):519-530

Next Generation Sequencing Reveals Novel Mutations in Mismatch Repair Genes and Other Cancer Predisposition Genes in Asian Patients with Suspected Lynch Syndrome

Authors: Ow, Samuel G.W., Tan, Kar Tong, Yang, Henry, Yap, Hui-Ling, Sapari, Nur Sabrina Binte, Ong, Pei Yi, Soong, Richie, Lee, Soo-Chin

Source: In Clinical Colorectal Cancer December 2019 18(4):e324-e334

Using next-generation sequencing (NGS) platform to diagnose pathogenic germline BRCA1/2 mutations from archival tumor specimens

Authors: Ong, Pei Yi, Poon, Song Ling, Tan, Kien Thiam, Putti, Thomas Choudary, Ow, Samuel Guan Wei, Chen, Shu-Jen, Chen, Chien-Hong, Lee, Soo-Chin

Source: In Gynecologic Oncology November 2019 155(2):275-279

Targeting Cell Metabolism as Cancer Therapy

Authors: Ngoi, Natalie Y.L., Eu, Jie Qing, Hirpara, Jayshree, Wang, Lingzhi, Lim, Joline S.J., Lee, Soo-Chin, Lim, Yaw-Chyn, Pervaiz, Shazib, Goh, Boon Cher, Wong, Andrea L.A.

Source: Antioxidants & redox signaling. 32(5):285-308

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100098721225.0x000001&indx=1&recIds=ETOCvdc_100098721225.0x000001

Safety and tolerability of cryocompression as a method of enhanced limb hypothermia to reduce taxane-induced peripheral neuropathy

Authors: Bandla, Aishwarya, Tan, Stacey, Kumarakulasinghe, Nesaretnam Barr, Huang, Yiqing, Ang, Sally, Magarajah, Gayathiri, Hairom, Zarinah, Lim, Joline Si Jing, Wong, Alvin, Chan, Gloria, Ngoi, Natalie, Ang, Emily, Lee, Yee Mei, Chan, Amanda, Lee, Soo-Chin, Thakor, Nitish, Wilder-Smith, Einar, Sundar, Raghav

Source: Supportive care in cancer. 28(8):3691-3699

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100168136006.0x000001&indx=1&recIds=ETOCvdc_100168136006.0x000001

A phase 3 study (PATHWAY) of palbociclib plus tamoxifen in patients with HR-positive/HER2-negative advanced breast cancer.

Authors: Noguchi, Emi, Yamanaka, Takashi, Mukai, Hirofumi, Yamamoto, Naohito, Chung, Chi-Feng, Lu, Yen-Shen, Chang, Dwan-Ying, Sohn, Joohyuk, Kim, Gun Min, Lee, Kyung-Hun, Lee, Soo-Chin, Iwasa, Tsutomu, Iwata, Hiroji, Watanabe, Kenichi, Jung, Kyung Hae, Tanabe, Yuko, Kang, Seok Yun, Yasojima, Hiroyuki, Aogi, Kenjiro, Tokunaga, Eriko

Source: NPJ Breast Cancer; 8/22/2024, Vol. 10 Issue 1, p1-10, 10p

A phase Ib/II study of pacritinib, an interleukin 1 receptor associated kinase 1 (IRAK1) inhibitor, in patients (pts) with solid tumors harboring the 1q21.3 copy number amplification (CNA).

Authors: Lim, Joline Si Jing, Aau, Mei Yee, Yeong, Joe, Goh, Boon Cher, Yong, Wei Peng, Soo, Ross A., Wong, Andrea, Tan, David Shao Peng, Chee, Cheng Ean, Sundar, Raghav, Jeyasekharan, Anand Devaprasath, Wong, Calista, Chen, Polly Leilei, Liu, Hai Yan, Yu, Qiang, Tam, Wai Leong, Lee, Soo-Chin

Source: Journal of Clinical Oncology; 2024 Supplement, Vol. 42, p43-43, 15p