Diverse landscape of dermatologic toxicities from small‐molecule inhibitor cancer therapy

Authors: Seervai, Riyad N. H., Cho, Woo Cheal, Chu, Emily Y., Marques‐Piubelli, Mario L., Ledesma, Debora A., Richards, Kristen, Heberton, Meghan M., Nelson, Kelly C., Nagarajan, Priyadharsini, Torres‐Cabala, Carlos A., Prieto, Victor G., Curry, Jonathan L.

Source: Journal of cutaneous pathology. 49(1):61-81

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100136531056.0x000001&indx=1&recIds=ETOCvdc_100136531056.0x000001

Hypertrophic lichenoid dermatitis immune‐related adverse event during combined immune checkpoint and exportin inhibitor therapy: A diagnostic pitfall for superficially invasive squamous cell carcinoma

Authors: Marques‐Piubelli, Mario L., Tetzlaff, Michael T., Nagarajan, Priyadharsini, Duke, Taylor C., Glitza Oliva, Isabella C., Ledesma, Debora A., Aung, Phyu P., Torres‐Cabala, Carlos A., Wistuba, Ignacio I., Prieto, Victor G., Nelson, Kelly C., Curry, Jonathan L.

Source: Journal of cutaneous pathology. 47(10):954-959

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100107459410.0x000001&indx=1&recIds=ETOCvdc_100107459410.0x000001

Apoptosis Pathway–Associated Proteins Are Frequently Expressed in Melanoma: A Study of 32 Cases With Focus on Acral Lentiginous Melanoma

Authors: Ledesma, Debora A., Marques-Piubelli, Mario L., Li-Ning-Tapia, Elsa, Hudgens, Courtney, Gu, Jun, Lazcano, Rossana, Casavilca-Zambrano, Sandro, Castillo, Miluska, Davies, Michael A., Hwu, Wen-Jen, Aung, Phyu P., Giubellino, Alessio, Curry, Jonathan L., Torres-Cabala, Carlos

Source: The American Journal of Dermatopathology; July 2024, Vol. 46 Issue: 7 p410-415, 6p

Nectin‐4 expression in a subset of cutaneous adnexal carcinomas: A potential target for therapy with enfortumab vedotin.

Authors: Cho, Woo Cheal, Saade, Rayan, Nagarajan, Priyadharsini, Aung, Phyu P., Milton, Denái R., Marques‐Piubelli, Mario L., Hudgens, Courtney, Ledesma, Debora, Nelson, Kelly, Ivan, Doina, Zhang, Miao, Torres‐Cabala, Carlos A., Campbell, Matthew, Alhalabi, Omar, Prieto, Victor G., Wistuba, Ignacio I., Esmaeli, Bita, Curry, Jonathan L.

Source: Journal of Cutaneous Pathology; May2024, Vol. 51 Issue 5, p360-367, 8p

Subject Terms: CARCINOMA, BENIGN tumors, SEBACEOUS gland diseases, TRANSITIONAL cell carcinoma, DUCTAL carcinoma, BREAST

Differential Upregulation of Th1/Th17-Associated Proteins and PD-L1 in Granulomatous Mycosis Fungoides.

Authors: Marques-Piubelli, Mario L., Navarrete, Jesus, Ledesma, Debora A., Hudgens, Courtney W., Lazcano, Rossana N., Alani, Ali, Huen, Auris, Duvic, Madeleine, Nagarajan, Priyadharsini, Aung, Phyu P., Wistuba, Ignacio I., Curry, Jonathan L., Miranda, Roberto N., Torres-Cabala, Carlos A.

Source: Cells (2073-4409); Mar2024, Vol. 13 Issue 5, p419, 12p

Subject Terms: MYCOSIS fungoides, PROGRAMMED death-ligand 1, IMMUNE checkpoint proteins, CELL transformation, SKIN diseases

Cellular and Molecular Mechanisms of Liver Fibrosis in Patients with NAFLD.

Authors: Sanchez, Jessica I., Parra, Edwin R., Jiao, Jingjing, Solis Soto, Luisa M., Ledesma, Debora A., Saldarriaga, Omar A., Stevenson, Heather L., Beretta, Laura

Source: Cancers; Jun2023, Vol. 15 Issue 11, p2871, 15p

Subject Terms: RNA analysis, DISEASE progression, BIOMARKERS, INTERLEUKINS, BIOPSY, STAINS & staining (Microscopy), ANALYSIS of variance, CONFIDENCE intervals, ONCOGENES, MULTIVARIATE analysis, CIRRHOSIS of the liver, FIBROSIS, NON-alcoholic fatty liver disease, MACROPHAGES, RISK assessment, SEVERITY of illness index, GENE expression profiling, RESEARCH funding, FACTOR analysis, DESCRIPTIVE statistics, FLUORESCENT antibody technique, IMMUNOGENETICS, CHEMOKINES, T cells, ANALYTICAL chemistry techniques, DATA analysis software, DISEASE risk factors

Geographic Terms: TEXAS

Incidence, timing, and predictors of CNS metastasis in patients (Pts) with clinically localized cutaneous melanoma (CM).

Authors: Hasanov, Merve, Milton, Denai R., Patel, Sapna Pradyuman, Tawbi, Hussein Abdul-Hassan, Glitza, Isabella Claudia, Ferguson, Sherise D., Ledesma, Debora Alexandra, Torres-Cabala, Carlos A., Lazar, Alexander J., Burton, Elizabeth M., Gershenwald, Jeffrey E., Haydu, Lauren Elaine, Davies, Michael A.

Source: Journal of clinical oncology. 39(15 suppl):9580-9580

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100173224047.0x000001&indx=1&recIds=ETOCvdc_100173224047.0x000001

CD73 expression defines immune, molecular, and clinicopathological subgroups of lung adenocarcinoma.

Authors: Rocha, Pedro, Salazar, Ruth, Zhang, Jiexin, Ledesma, Debora, Solorzano, Jose L., Mino, Barbara, Villalobos, Pamela, Dejima, Hitoshi, Douse, Dzifa Y., Diao, Lixia, Mitchell, Kyle Gregory, Le, Xiuning, Zhang, Jianjun, Weissferdt, Annikka, Parra-Cuentas, Edwin, Cascone, Tina, Rice, David C., Sepesi, Boris, Kalhor, Neda, Moran, Cesar

Source: Cancer Immunology, Immunotherapy; Jul2021, Vol. 70 Issue 7, p1965-1976, 12p

Subject Terms: PROTEIN expression, IMMUNOSUPPRESSION, BIOMARKERS, ADENOCARCINOMA, IMMUNE checkpoint inhibitors, LUNGS

Correction to: CD73 expression defines immune, molecular, and clinicopathological subgroups of lung adenocarcinoma.

Authors: Rocha, Pedro, Salazar, Ruth, Zhang, Jiexin, Ledesma, Debora, Solorzano, Jose L., Mino, Barbara, Villalobos, Pamela, Dejima, Hitoshi, Douse, Dzifa Y., Diao, Lixia, Mitchell, Kyle Gregory, Le, Xiuning, Zhang, Jianjun, Weissferdt, Annikka, Parra-Cuentas, Edwin, Cascone, Tina, Rice, David C., Sepesi, Boris, Kalhor, Neda, Moran, Cesar

Source: Cancer Immunology, Immunotherapy; Jul2021, Vol. 70 Issue 7, p1977-1978, 2p

Subject Terms: ADENOCARCINOMA, LUNGS

Intestinal toxicity to CTLA-4 blockade driven by IL-6 and myeloid infiltration

Authors: Zhou, Yifan, Medik, Yusra B., Patel, Bhakti, Zamler, Daniel B., Chen, Sijie, Chapman, Thomas, Schneider, Sarah, Park, Elizabeth M., Babcock, Rachel L., Chrisikos, Taylor T., Kahn, Laura M., Dyevoich, Allison M., Pineda, Josue E., Wong, Matthew C., Mishra, Aditya K., Cass, Samuel H., Cogdill, Alexandria P., Johnson, Daniel H., Johnson, Sarah B., Wani, Khalida, Ledesma, Debora A., Hudgens, Courtney W., Wang, Jingjing, Wadud Khan, Md Abdul, Peterson, Christine B., Joon, Aron Y., Peng, Weiyi, Li, Haiyan S., Arora, Reetakshi, Tang, Ximing, Raso, Maria Gabriela, Zhang, Xuegong, Foo, Wai Chin, Tetzlaff, Michael T., Diehl, Gretchen E., Clise-Dwyer, Karen, Whitley, Elizabeth M., Gubin, Matthew M., Allison, James P., Hwu, Patrick, Ajami, Nadim J., Diab, Adi, Wargo, Jennifer A., Watowich, Stephanie S.

Source: The Journal of Experimental Medicine; February 2023, Vol. 220 Issue: 2 pe20221333-e20221333, 1p

48218 Preclinical modeling of BRAF(V600E)/PTEN-/- melanoma leptomeningeal disease (LMD) to assess intrathecal checkpoint blockade.

Authors: Guerrieri, Renato A.¹, Fischer, Grant M.¹, Knighton, Barbara G.¹, Hudgens, Courtney W.¹, Ledesma, Debora A.¹, Davies, Michael A.¹, Ferguson, Sherise D.¹

Source: Journal of Clinical & Translational Science; 2021 Supplement, Vol. 5, p88-88, 1p