Mutant FOXO1 controls an oncogenic network via enhancer accessibility

Authors: Layden, Hillary M. ¹, Ellis, Jacob D. ¹, Bomber, Monica L. ¹, Bartlett, Luke N. ¹, Hiebert, Scott W. ^{1, 2, 6, ∗}, Stengel, Kristy R. ^{3, 4, 5, ∗∗}

Source: In Cell Genomics 10 April 2024 4(4)

Chemical-genetics refines transcription factor regulatory circuits

Authors: Layden, Hillary M., Johnson, Anna E., Hiebert, Scott W.

Source: In Trends in Cancer January 2024 10(1):65-75

Human SMARCA5 is continuously required to maintain nucleosome spacing

Authors: Bomber, Monica L., Wang, Jing, Liu, Qi, Barnett, Kelly R., Layden, Hillary M., Hodges, Emily, Stengel, Kristy R., Hiebert, Scott W.

Source: In Molecular Cell 16 February 2023 83(4):507-522

PAX3-FOXO1 coordinates enhancer architecture, eRNA transcription, and RNA polymerase pause release at select gene targets

Authors: Zhang, Susu, Wang, Jing, Liu, Qi, McDonald, W. Hayes, Bomber, Monica L., Layden, Hillary M., Ellis, Jacob, Borinstein, Scott C., Hiebert, Scott W., Stengel, Kristy R.

Source: In Molecular Cell 1 December 2022 82(23):4428-4442

A protocol for rapid degradation of endogenous transcription factors in mammalian cells and identification of direct regulatory targets

Authors: Layden, Hillary M., Eleuteri, Nicholas A., Hiebert, Scott W., Stengel, Kristy R.

Source: In STAR Protocols 18 June 2021 2(2)

Jedi‐1/MEGF12‐mediated phagocytosis controls the pro‐neurogenic properties of microglia in the ventricular‐subventricular zone.

Authors: Morrison, Vivianne E, Houpert, Matthew G, Trapani, Jonathan B, Brockman, Asa A, Kingsley, Philip J, Katdare, Ketaki A., Layden, Hillary M, Hiebert, Scott W, Nguena‐Jones, Gabriela, Trevisan, Alexandra J, Maguire‐Zeiss, Kathleen A, Marnett, Lawrence J, Bix, Gregory J, Ihrie, Rebecca A, Carter, Bruce D

Source: Alzheimer's & Dementia: The Journal of the Alzheimer's Association; Dec2023 Supplement 13, Vol. 19, p1-2, 2p

Synergistic melanoma cell death mediated by inhibition of both MCL1 and BCL2 in high-risk tumors driven by NF1/PTEN loss

Authors: He, Shuning, Zimmerman, Mark W., Layden, Hillary M., Berezovskaya, Alla, Etchin, Julia, Martel, Megan W., Thurston, Grace, Jing, Chang-Bin, van Rooijen, Ellen, Kaufman, Charles K., Rodig, Scott J., Zon, Leonard I., Patton, E. Elizabeth, Mansour, Marc R., Look, A. Thomas

Source: Oncogene; September 2021, Vol. 40 Issue: 38 p5718-5729, 12p

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Synergy between loss of NF1 and overexpression of MYCN in neuroblastoma is mediated by the GAP- related domain.

Authors: Shuning He, Mansour, Marc R., Zimmerman, Mark W., Dong Hyuk Ki, Layden, Hillary M., Koshi Akahane, Gjini, Evisa, de Groh, Eric D., Perez-Atayde, Antonio R., Shizhen Zhu, Epstein, Jonathan A., Look, A. Thomas

Source: eLife; 2016, p1-20, 20p

Chemical-genetics refines transcription factor regulatory circuits

Authors: Layden, Hillary M., Johnson, Anna E., Hiebert, Scott W.

Source: Trends in Cancer; 20230101, Issue: Preprints

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