MicroRNA-31-3p Is Involved in Substance P (SP)-Associated Inflammation in Human Colonic Epithelial Cells and Experimental Colitis

Authors: Fang, Kai, Law, Ivy Ka Man, Padua, David, Sideri, Aristea, Huang, Vanessa, Kevil, Christopher G., Iliopoulos, Dimitrios, Pothoulakis, Charalabos

Source: In The American Journal of Pathology March 2018 188(3):586-599

Diminished Expression of Corticotropin-Releasing Hormone Receptor 2 in Human Colon Cancer Promotes Tumor Growth and Epithelial-to-Mesenchymal Transition via Persistent Interleukin-6/Stat3 Signaling

Authors: Rodriguez, Jorge A., Huerta-Yepez, Sara, Law, Ivy Ka Man, Baay-Guzman, Guillermina J., Tirado-Rodriguez, Belen, Hoffman, Jill M., Iliopoulos, Dimitrios, Hommes, Daniel W., Verspaget, Hein W., Chang, Lin, Pothoulakis, Charalabos, Baritaki, Stavroula

Source: In Cellular and Molecular Gastroenterology and Hepatology November 2015 1(6):610-630

Identification of a Novel Substance P–Neurokinin-1 Receptor MicroRNA-221-5p Inflammatory Network in Human Colonic Epithelial Cells

Authors: Fang, Kai, Sideri, Aristea, Law, Ivy Ka Man, Bakirtzi, Kyriaki, Polytarchou, Christos, Iliopoulos, Dimitrios, Pothoulakis, Charalabos

Source: In Cellular and Molecular Gastroenterology and Hepatology September 2015 1(5):503-515

362 MIR-24-3P REGULATION OF CELL SURVIVAL MODULATES EPITHELIAL RECOVERY AFTER COLITIS

Authors: Rankin, Carl R., Soroosh, Artin, Fang, Kai, Hoffman, Jill M., Law, Ivy Ka Man, Lokhandwala, Zulfiqar A., Padua, David, Pothoulakis, Charalabos

Source: Gastroenterology. 160(6):S-69-S-69

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100140882103.0x000001&indx=1&recIds=ETOCvdc_100140882103.0x000001

360 SP/NK1R SIGNALING REGULATES POSTTRANSCRIPTIONAL MODIFICATION AND EXOSOMAL SORTING OF MIR-21 IN HUMAN COLONIC EPITHELIAL CELLS VIA ADORA2B RECEPTOR STIMULATION

Authors: Wani, Sameena, Law, Ivy Ka Man, Pothoulakis, Charalabos

Source: Gastroenterology. 160(6):S-68-S-68

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100140882156.0x000001&indx=1&recIds=ETOCvdc_100140882156.0x000001

The Neurotensin–HIF-1α–VEGFα Axis Orchestrates Hypoxia, Colonic Inflammation, and Intestinal Angiogenesis

Authors: Bakirtzi, Kyriaki, West, Gail, Fiocchi, Claudio, Law, Ivy Ka Man, Iliopoulos, Dimitrios, Pothoulakis, Charalabos

Source: In The American Journal of Pathology December 2014 184(12):3405-3414

Neurotensin Promotes the Development of Colitis and Intestinal Angiogenesis via Hif-1α-miR-210 Signaling

Authors: Bakirtzi, Kyriaki, Law, Ivy Ka Man, Xue, Xiang, Iliopoulos, Dimitrios, Shah, Yatrik M., Pothoulakis, Charalabos

Source: Journal of immunology. 196(10):4311-4321

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCRN606080291&indx=1&recIds=ETOCRN606080291

636 UNRAVELLING THE MOLECULAR MECHANISM RESPONSIBLE FOR THE SELECTIVE SORTING OF MICRORNA-21 INTO THE SUBSTANCE PINDUCED COLONIC EPITHELIAL EXOSOMES

Authors: wani, sameena, Law, Ivy Ka Man, Pothoulakis, Charalabos

Source: Gastroenterology. 158(6):S-137-S-137

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100131779171.0x000001&indx=1&recIds=ETOCvdc_100131779171.0x000001

639 NEUROTENSIN (NT) SIGNALING-ASSOCIATED LONG NON-CODING RNA (LNCRNA) UCA1 IS A MEDIATOR OF HYPOXIC RESPONSE IN HUMAN COLONOCYTES

Authors: Law, Ivy Ka Man, wani, sameena, Pothoulakis, Charalabos

Source: Gastroenterology. 158(6):S-137-S-137

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100131779149.0x000001&indx=1&recIds=ETOCvdc_100131779149.0x000001

1098 COLONIC EPITHELIAL CELL-SPECIFIC AFTIPHILIN (AFTPH) REGULATES ACTIN ORGANIZATION THROUGH REGULATING F-ACTIN/G-ACTIN RATIO IN VITRO AND INTESTINAL LENGTH IN VIVO

Authors: Law, Ivy Ka Man, Rankin, Carl R., Pothoulakis, Charalabos

Source: Gastroenterology. 158(6):S-213-S-213

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100131771803.0x000001&indx=1&recIds=ETOCvdc_100131771803.0x000001

Elafin inhibits obesity, hyperglycemia, and liver steatosis in high-fat diet-treated male mice

Authors: Wang, Jiani, Ortiz, Christina, Fontenot, Lindsey, Mukhopadhyay, Riya, Xie, Ying, Law, Ivy Ka Man, Shih, David Q., Mattai, S. Anjani, Li, Zhaoping, Koon, Hon Wai

Source: Scientific reports. 10(1)

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100174702755.0x000001&indx=1&recIds=ETOCvdc_100174702755.0x000001

Neurotensin-induced Proinflammatory Signaling in Human Colonocytes Is Regulated by β-Arrestins and Endothelin-converting Enzyme-1-dependent Endocytosis and Resensitization of Neurotensin Receptor 1

Authors: Law, Ivy Ka Man, Murphy, Jane E., Bakirtzi, Kyriaki, Bunnett, Nigel W., Pothoulakis, Charalabos

Source: In Journal of Biological Chemistry 27 April 2012 287(18):15066-15075

361 AFTIPHILIN-MEDIATED PARACELLULAR FLUX AND MYOSIN LIGHT CHAIN KINASE ACTIVATION REGULATES COLONIC EPITHELIAL CELL PERMEABILITY IN VITRO

Authors: Law, Ivy Ka Man, Rankin, Carl R., Fang, Kai, Pothoulakis, Charalabos

Source: Gastroenterology. 160(6):S-68-S-69

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100140882109.0x000001&indx=1&recIds=ETOCvdc_100140882109.0x000001

Mo1104 – The Trans-Golgi Network Protein Aftiphilin Regulates Colonic Epithelial Cell Migration and is Crucial to Embryonic Development

Authors: Law, Ivy Ka Man, Pothoulakis, Charalabos

Source: Gastroenterology. 156(6):S-708-S-708

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100080553644.0x000001&indx=1&recIds=ETOCvdc_100080553644.0x000001

Tu1211 AN ANTISENSE OLIGONUCLEOTIDE FOR MICRORNA-24-3P EXHIBITS SAFE AND EFFICIENT KNOCKDOWN ABILITY IN VITRO AND IN VIVO AND INHIBITS TRINITROBENZENE SULFONIC ACID (TNBS) COLITIS

Authors: Soroosh, Artin, Rankin, Carl R., Fang, Kai, Lokhandwala, Zulfiqar A., Law, Ivy Ka Man, Patel, Ami, Bui, Diane, Iliopoulos, Dimitrios, Padua, David, Pothoulakis, Charalabos

Source: Gastroenterology. 158(6):S-1019-S-1020

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100129191106.0x000001&indx=1&recIds=ETOCvdc_100129191106.0x000001

Mo1117 – Gavage As-Mir-214-3P Reduces Inflammation in Experimental Colitis

Authors: Fang, Kai, Law, Ivy Ka Man, Neman, Sophia, Iliopoulos, Dimitrios, Pothoulakis, Charalabos

Source: Gastroenterology. 156(6):S-711-S-712

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100080553505.0x000001&indx=1&recIds=ETOCvdc_100080553505.0x000001

985 - Human Long Non-Coding RNA (LNCRNA) CCAT1 and UCA1 Regulate Proinflammatory Response and Cell Migration in Human and Mouse Intestinal Epithelial Cells

Authors: Law, Ivy Ka Man, Padua, David M., Iliopoulos, Dimitrios, Pothoulakis, Charalabos

Source: Gastroenterology. 154(6):S-183-S-184

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100085558900.0x000001&indx=1&recIds=ETOCvdc_100085558900.0x000001

Long Non-Coding RNA (LNCRNA) Profiling Reveals Overexpression of UCA1 and CCAT1 in Human Colonocytes Stimulated by Neurotensin and in Colonic Mucosal Tissues from Ulcerative Colitis (UC) Patients

Authors: Law, Ivy Ka Man, Padua, David M., Iliopoulos, Dimitrios, Pothoulakis, Charalabos

Source: Gastroenterology. 152(5):S143-S144

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100054022294.0x000001&indx=1&recIds=ETOCvdc_100054022294.0x000001

P127 THE TRANS-GOLGI NETWORK PROTEIN AFTIPHILIN REGULATES COLONIC EPITHELIAL CELL MIGRATION AND IS CRUCIAL TO EMBRYONIC DEVELOPMENT

Authors: Law, Ivy Ka Man, Pothoulakis, Charalabos

Source: Inflammatory bowel diseases. 25(1):S61-S61

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100086098517.0x000001&indx=1&recIds=ETOCvdc_100086098517.0x000001

Role and mechanisms of exosomal miRNAs in IBD pathophysiology.

Authors: Wani, Sameena¹, Law, Ivy Ka Man¹, Pothoulakis, Charalabos¹ cpothoulakis@mdenet.ucla.edu

Source: American Journal of Physiology: Gastrointestinal & Liver Physiology. Dec2020, Vol. 319 Issue 6, p646-654. 9p.

Subject Terms: *MICRORNA, *SECRETORY granules, *INFLAMMATORY bowel diseases, *NON-coding RNA, *PATHOLOGICAL physiology, *PLANT gene silencing