Hurdles in new drug development in rheumatic diseases

Authors: Lavie, Frederic ^*, Rooney, Terence

Source: In Joint Bone Spine July 2024 91(4)

Patient Profiles in Randomized Controlled Trials Versus a Real-World Study in Psoriatic Arthritis: Scoping Review and Metaanalysis.

Authors: Alle, Gelsomina, Lopez-Medina, Clementina, Siebert, Stefan, Lavie, Frédéric, Noel, Wim, Smolen, Josef S., Gossec, Laure

Source: Journal of Rheumatology; Feb2025, Vol. 52 Issue 2, p138-144, 7p

Subject Terms: ANTIRHEUMATIC agents, BODY surface area, PSORIATIC arthritis, RANDOMIZED controlled trials, BIOTHERAPY

Treat to target versus standard of care for patients with Crohn's disease treated with ustekinumab (STARDUST): an open-label, multicentre, randomised phase 3b trial

Authors: Rocca, Rodolfo, Lopes, Susana, Caprioli, Flavio, Ardizzone, Sandro, Echarri Piudo, Ana, Gionchetti, Paolo, Roblin, Xavier, Seidler, Ursula, Andersson, David, Patel, Kamal, Desreumaux, Pierre, Saibeni, Simone, From, Gustav, Fedurco, Miroslav, Gregus, Milos, Bouhnik, Yoram, Luegering, Andreas, Cosintino, Rocco, Bunganic, Ivan, Ramos, Jaime, Aguas Peris, Mariam, Dewit, Olivier, Principi, Mariabeatrice, Wesley, Emma, Lago, Paula, Nancey, Stephane, Martín Arranz, María Dolores, Hindryckx, Pieter, Orlando, Ambrogio, Geccherle, Andrea, Annunziata, Maria Laura, Hayee, Bu'hussain, Balaz, Jozef, Portela, Francisco, Gilletta, Cyrielle, Kucharzik, Torsten, Mínguez, Miguel, Gisbert, Javier Pérez, Casbas, Ana Gutiérrez, Louis, Edouard, Marino, Marco, Parkes, Gareth, Cummings, Fraser, Jharap, Bindia, Kjeldsen, Jens, Correia, Luís, Ministro, Paula, Ebert, Matthias, Hertervig, Erik, Staessen, Dirk, Dutré, Joris, Colard, Arnaud, Morrison, Graham, Glerup, Henning, Dahlerup, Jens Frederik, Wolfhagen, Frank, Batovsky, Marian, Molnar, Martin, Kadleckova, Barbora, Caldeira, Paulo, Laharie, David, Hebuterne, Xavier, Bonaz, Bruno, Allez, Matthieu, Fischer, Andreas, Hinojosa Del Val, Joaquín Ernesto, Ciria, Miriam Mañosa, Herrera Justiniano, Jose Manuel, Soderman, Charlotte, Chandy, Rajiv, Mowat, Craig, Irving, Peter, Fallingborg, Jan, Matous, Jan, Douda, Tomas, Altwegg, Romain, Benitez, Jose Manuel, Arroyo Villarino, María Teresa, Capón, Jordi Guardiola, Vicenc, Daniel Ginard, Dewint, Pieter, Almer, Sven, Kindt, Sebastien, Danese, Silvio ^*, Vermeire, Severine, D'Haens, Geert, Panés, Julian, Dignass, Axel, Magro, Fernando, Nazar, Maciej, Le Bars, Manuela, Lahaye, Marjolein, Ni, Lioudmila, Bravata, Ivana, Lavie, Frederic, Daperno, Marco, Lukáš, Milan, Armuzzi, Alessandro, Löwenberg, Mark, Gaya, Daniel R, Peyrin-Biroulet, Laurent

Source: In The Lancet Gastroenterology & Hepatology April 2022 7(4):294-306

Guselkumab in Biologic-Naïve Patients with Active Psoriatic Arthritis in Russia: A Post Hoc Analysis of the DISCOVER-1 and -2 Randomized Clinical Trials.

Authors: Mease, Philip, Korotaeva, Tatiana, Shesternya, Pavel, Kokhan, Muza, Rukavitsyn, Anton, Vasilchenkov, Dmitry, Sharaf, Mohamed, Lavie, Frédéric, Deodhar, Atul

Source: Rheumatology & Therapy; Dec2024, Vol. 11 Issue 6, p1551-1567, 17p

Subject Terms: ANKYLOSING spondylitis, PATIENT reported outcome measures, PATIENT safety, CLINICAL trials, RHEUMATOLOGY

Sustained response to guselkumab regardless of baseline characteristics in patients with active psoriatic arthritis and inadequate response to TNF inhibitors: results from the phase 3b COSMOS clinical trial.

Authors: McInnes, Iain B., Sewerin, Philipp, Sharaf, Mohamed, Efficace, Michela, Lavie, Frédéric, Zimmermann, Miriam, Coates, Laura C.

Source: RMD Open; Oct2024, Vol. 10 Issue 4, p1-12, 12p

Physicians in the pharmaceutical industry: their roles, motivations, and perspectives

Authors: Sweiti, Hussein, Wiegand, Frank, Bug, Christoph, Vogel, Martin, Lavie, Frederic, Winiger-Candolfi, Ivo, Schuier, Maximilian

Source: In Drug Discovery Today September 2019 24(9):1865-1870

Early access to health products in France: Major advances of the French “Conseil stratégique des industries de santé” (CSIS) to be implemented (modalities, regulations, funding)

Authors: Boudali, Lotfi, Blin, Olivier, de Chalus, Thibault, Fruchet, Estelle, Grande, Mathilde, Grudé, Françoise, Hoog-Labouret, Natalie, Kauv, Céline, Lavie, Frédéric, Le Jeunne, Claire, Meillier, Fabrice, Pouletty-Lefebvre, Brigitte, Richard, Anne-Céline, Mazaleyrat, Benjamin, Monard, Adrien, Albin, Nicolas, Chassagnol, Frédéric, Bergmann, Jean-François

Source: In Therapies February 2019 74(1):103-117

Accès précoce aux produits de santé en France : des avancées majeures du CSIS (Conseil stratégique des industries de santé) à concrétiser (modalités, réglementations, financements)

Authors: Boudali, Lotfi, Blin, Olivier, de Chalus, Thibault, Fruchet, Estelle, Grande, Mathilde, Grudé, Françoise, Hoog-Labouret, Natalie, Kauv, Céline, Lavie, Frédéric, Le Jeunne, Claire, Meillier, Fabrice, Pouletty-Lefebvre, Brigitte, Richard, Anne-Céline, Mazaleyrat, Benjamin, Monard, Adrien, Albin, Nicolas, Chassagnol, Frédéric, Bergmann, Jean-François

Source: In Therapies February 2019 74(1):87-101

« L’IA va révolutionner la filière du médicament ».

Authors: Lavie, Frédéric¹

Source: Actulabo. 2/12/2025, Issue 473, p7-7. 1p.

Subject Terms: *Artificial intelligence, *Simulation methods & models, Biological systems, Drug development, Clinical trials

Geographic Terms: France

Prognosis and follow-up of psoriatic arthritis with peripheral joint involvement: Development of recommendations for clinical practice based on published evidence and expert opinion

Authors: Lavie, Frédéric, Salliot, Carine, Dernis, Emmanuelle, Claudepierre, Pascal, Schaeverbeke, Thierry, Tebib, Jacques, Goupille, Philippe, Cantagrel, Alain, Flipo, René-Marc, Gaudin, Philippe, Le Loët, Xavier, Maillefert, Jean-Francis, Paul, Carle, Saraux, Alain, Wendling, Daniel, Combe, Bernard

Source: In Joint Bone Spine October 2009 76(5):540-546

Diagnosis of peripheral psoriatic arthritis: Recommendations for clinical practice based on data from the literature and experts opinion

Authors: Salliot, Carine, Dernis, Emmanuelle, Lavie, Frédéric, Cantagrel, Alain, Gaudin, Philippe, Wendling, Daniel, Claudepierre, Pascal, Flipo, René-Marc, Goupille, Philippe-M., Le Loët, Xavier, Maillefert, Jean-François, Paul, Carle, Saraux, Alain, Schaeverbeke, Thierry, Tebib, Jacques, Combe, Bernard

Source: In Joint Bone Spine October 2009 76(5):532-539

Pharmacological treatment (biotherapy excluded) of peripheral psoriatic arthritis: Development of recommendations for clinical practice based on data from the literature and experts opinion

Authors: Dernis, Emmanuelle, Lavie, Frédéric, Salliot, Carine, Flipo, René-Marc, Saraux, Alain, Maillefert, Jean-Francis, Paul, Carle, Goupille, Philippe, Cantagrel, Alain, Claudepierre, Pascal, Gaudin, Philippe, Tebib, Jacques, Wendling, Daniel, Schaeverbeke, Thierry, Le Loët, Xavier, Combe, Bernard

Source: In Joint Bone Spine October 2009 76(5):524-531

Pharmacotherapy (excluding biotherapies) for ankylosing spondylitis: Development of recommendations for clinical practice based on published evidence and expert opinion

Authors: Lavie, Frédéric, Pavy, Stephan, Dernis, Emmanuelle, Goupille, Philippe, Cantagrel, Alain, Tebib, Jacques, Claudepierre, Pascal, Flipo, René Marc, Le Loët, Xavier, Maillefert, Jean-Francis, Mariette, Xavier, Saraux, Alain, Schaeverbeke, Thierry, Wendling, Daniel, Combe, Bernard

Source: In Joint Bone Spine 2007 74(4):346-352

Clinical and laboratory follow-up for treating and monitoring patients with ankylosing spondylitis: Development of recommendations for clinical practice based on published evidence and expert opinion

Authors: Dernis, Emmanuelle, Lavie, Frédéric, Pavy, Stéphan, Wendling, Daniel, Flipo, René-Marc, Saraux, Alain, Cantagrel, Alain, Claudepierrre, Pascal, Goupille, Philippe, Le Loët, Xavier, Maillefert, Jean Francis, Mariette, Xavier, Schaeverbeke, Thierry, Tebib, Jacques, Combe, Bernard

Source: In Joint Bone Spine 2007 74(4):330-337

Imaging for the diagnosis and follow-up of ankylosing spondylitis: Development of recommendations for clinical practice based on published evidence and expert opinion

Authors: Pavy, Stephan, Dernis, Emmanuelle, Lavie, Frédéric, Maillefert, Jean-Francis, Mariette, Xavier, Schaeverbeke, Thierry, Cantagrel, Alain, Claudepierre, Pascal, Flipo, René-Marc, Goupille, Philippe, Le Loet, Xavier, Saraux, Alain, Tebib, Jacques, Wendling, Daniel, Combe, Bernard

Source: In Joint Bone Spine 2007 74(4):338-345

Les traitements médicamenteux (hors biothérapie) dans la prise en charge de patients atteints de rhumatisme psoriasique périphérique : élaboration de recommandations pour la pratique clinique, à partir d’une analyse systématique de la littérature et de l’opinion d’experts: Pharmacological treatment (biotherapy excluded) of peripheral psoriatic arthritis: development of recommendations for clinical practice based on data from the literature and experts opinion

Authors: Dernis, Emmanuelle, Lavie, Fréderic, Salliot, Carine, Flipo, René-Marc, Saraux, Alain, Maillefert, Jean-Francis, Paul, Carle, Goupille, Philippe, Cantagrel, Alain, Claudepierre, Pascal, Gaudin, Philippe, Tebib, Jacques, Wendling, Daniel, Schaeverbeke, Thierry, Le Loët, Xavier, Combe, Bernard

Source: In Revue du rhumatisme 2007 74 Supplement 2:31-38

Diagnostic du rhumatisme psoriasique de forme périphérique : élaboration de recommandations pour la pratique clinique, à partir d’une analyse systématique de la littérature et de l’opinion d’experts: Diagnosis of peripheral psoriatic arthritis: recommendations for clinical practice based on data from the literature and experts opinion

Authors: Salliot, Carine, Dernis, Emmanuelle, Lavie, Frédéric, Cantagrel, Alain, Gaudin, Philippe, Wendling, Daniel, Claudepierre, Pascal, Flipo, René-Marc, Goupille, Philippe, Le Loët, Xavier, Maillefert, Jean-François, Paul, Carle, Saraux, Alain, Schaeverbeke, Thierry, Tebib, Jacques, Combe, Bernard

Source: In Revue du rhumatisme 2007 74 Supplement 2:15-22

Pronostic et suivi du rhumatisme psoriasique de forme périphérique : élaboration de recommandations pour la pratique clinique, à partir d’une analyse systématique de la littérature et de l’opinion d’experts: Prognosis and follow-up of psoriatic arthritis with peripheral joint involvement: development of recommendations for clinical practice based on published evidence and expert opinion

Authors: Lavie, Frédéric, Salliot, Carine, Dernis, Emmanuelle, Claudepierre, Pascal, Schaeverbeke, Thierry, Tebib, Jacques, Goupille, Philippe, Cantagrel, Alain, Flipo, René Marc, Gaudin, Philippe, Le Loët, Xavier, Maillefert, Jean-Francis, Paul, Carle, Saraux, Alain, Wendling, Daniel, Combe, Bernard

Source: In Revue du rhumatisme 2007 74 Supplement 2:23-30

CD4 CD25 high regulatory T cells are not impaired in patients with primary Sjögren's syndrome

Authors: Gottenberg, Jacques-Eric, Lavie, Frédéric, Abbed, Karim, Gasnault, Jacques, Le Nevot, Emilie, Delfraissy, Jean-François, Taoufik, Yassine, Mariette, Xavier

Source: In Journal of Autoimmunity 2005 24(3):235-242

Mo1519: CLINICAL AND ENDOSCOPIC OUTCOMES WITH USTEKINUMAB IN PATIENTS WITH CROHN’S DISEASE: RESULTS FROM THE LONG-TERM EXTENSION PERIOD OF THE STARDUST TRIAL

Authors: Peyrin-Biroulet, Laurent, Vermeire, Séverine, D’Haens, Geert R., Panés, Julian, Dignass, Axel, Magro, Fernando, Nazar, Maciej, Bars, Manuela Le, Lahaye, Marjolein, Ni, Lioudmila, Bravata, Ivana, Lavie, Frederic, Daperno, Marco, Lukas, Milan, Armuzzi, Alessandro, Löwenberg, Mark, Gaya, Daniel R., Danese, Silvio

Source: In Gastroenterology May 2022 162(7) Supplement:S